Adipokines, diabetes and atherosclerosis: an inflammatory association
Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, includi...
Ausführliche Beschreibung
Autor*in: |
Leandro Ceotto Freitas Lima [verfasserIn] Valdir de Andrade Barga [verfasserIn] Maria edo Socorro de França Silva [verfasserIn] Josiane de Campos Cruz [verfasserIn] Sérgio Henrique Sousa Santos [verfasserIn] Matheus Morais de Oliveira Monteiro [verfasserIn] Camille M Balarini [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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Übergeordnetes Werk: |
In: Frontiers in Physiology - Frontiers Media S.A., 2011, 6(2015) |
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Übergeordnetes Werk: |
volume:6 ; year:2015 |
Links: |
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DOI / URN: |
10.3389/fphys.2015.00304 |
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Katalog-ID: |
DOAJ048647551 |
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10.3389/fphys.2015.00304 doi (DE-627)DOAJ048647551 (DE-599)DOAJ8c7f60a81750460490a461d8c2d855ca DE-627 ger DE-627 rakwb eng QP1-981 Leandro Ceotto Freitas Lima verfasserin aut Adipokines, diabetes and atherosclerosis: an inflammatory association 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. Adipokines Adiponectin Atherosclerosis Obesity diabetes TNFα Physiology Valdir de Andrade Barga verfasserin aut Maria edo Socorro de França Silva verfasserin aut Josiane de Campos Cruz verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Matheus Morais de Oliveira Monteiro verfasserin aut Camille M Balarini verfasserin aut Camille M Balarini verfasserin aut In Frontiers in Physiology Frontiers Media S.A., 2011 6(2015) (DE-627)631498788 (DE-600)2564217-0 1664042X nnns volume:6 year:2015 https://doi.org/10.3389/fphys.2015.00304 kostenfrei https://doaj.org/article/8c7f60a81750460490a461d8c2d855ca kostenfrei http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00304/full kostenfrei https://doaj.org/toc/1664-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2015 |
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10.3389/fphys.2015.00304 doi (DE-627)DOAJ048647551 (DE-599)DOAJ8c7f60a81750460490a461d8c2d855ca DE-627 ger DE-627 rakwb eng QP1-981 Leandro Ceotto Freitas Lima verfasserin aut Adipokines, diabetes and atherosclerosis: an inflammatory association 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. Adipokines Adiponectin Atherosclerosis Obesity diabetes TNFα Physiology Valdir de Andrade Barga verfasserin aut Maria edo Socorro de França Silva verfasserin aut Josiane de Campos Cruz verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Matheus Morais de Oliveira Monteiro verfasserin aut Camille M Balarini verfasserin aut Camille M Balarini verfasserin aut In Frontiers in Physiology Frontiers Media S.A., 2011 6(2015) (DE-627)631498788 (DE-600)2564217-0 1664042X nnns volume:6 year:2015 https://doi.org/10.3389/fphys.2015.00304 kostenfrei https://doaj.org/article/8c7f60a81750460490a461d8c2d855ca kostenfrei http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00304/full kostenfrei https://doaj.org/toc/1664-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2015 |
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10.3389/fphys.2015.00304 doi (DE-627)DOAJ048647551 (DE-599)DOAJ8c7f60a81750460490a461d8c2d855ca DE-627 ger DE-627 rakwb eng QP1-981 Leandro Ceotto Freitas Lima verfasserin aut Adipokines, diabetes and atherosclerosis: an inflammatory association 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. Adipokines Adiponectin Atherosclerosis Obesity diabetes TNFα Physiology Valdir de Andrade Barga verfasserin aut Maria edo Socorro de França Silva verfasserin aut Josiane de Campos Cruz verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Matheus Morais de Oliveira Monteiro verfasserin aut Camille M Balarini verfasserin aut Camille M Balarini verfasserin aut In Frontiers in Physiology Frontiers Media S.A., 2011 6(2015) (DE-627)631498788 (DE-600)2564217-0 1664042X nnns volume:6 year:2015 https://doi.org/10.3389/fphys.2015.00304 kostenfrei https://doaj.org/article/8c7f60a81750460490a461d8c2d855ca kostenfrei http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00304/full kostenfrei https://doaj.org/toc/1664-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2015 |
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10.3389/fphys.2015.00304 doi (DE-627)DOAJ048647551 (DE-599)DOAJ8c7f60a81750460490a461d8c2d855ca DE-627 ger DE-627 rakwb eng QP1-981 Leandro Ceotto Freitas Lima verfasserin aut Adipokines, diabetes and atherosclerosis: an inflammatory association 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. Adipokines Adiponectin Atherosclerosis Obesity diabetes TNFα Physiology Valdir de Andrade Barga verfasserin aut Maria edo Socorro de França Silva verfasserin aut Josiane de Campos Cruz verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Sérgio Henrique Sousa Santos verfasserin aut Matheus Morais de Oliveira Monteiro verfasserin aut Camille M Balarini verfasserin aut Camille M Balarini verfasserin aut In Frontiers in Physiology Frontiers Media S.A., 2011 6(2015) (DE-627)631498788 (DE-600)2564217-0 1664042X nnns volume:6 year:2015 https://doi.org/10.3389/fphys.2015.00304 kostenfrei https://doaj.org/article/8c7f60a81750460490a461d8c2d855ca kostenfrei http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00304/full kostenfrei https://doaj.org/toc/1664-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2015 |
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Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. |
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Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. |
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Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. |
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|
score |
7.398505 |