Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test

Punica granatum L., locally known as romanzeira, is native to Asia but found throughout Brazil. P. granatum is used for treating inflammatory, infectious and respiratory diseases. The aim of this study was to evaluate the chromatography and genotoxicity of an aqueous extract of P. granatum (pomegran...
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Gespeichert in:

Autor*in:	Andrielle Wouters Kuhn [verfasserIn] Marília Tedesco [verfasserIn] Aline Augusti Boligon [verfasserIn] Margareth Linde Athayde [verfasserIn] Haywood Dail Laughinghouse IV [verfasserIn] Solange Bosio Tedesco [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Punica granatum L./fitoquímica Punica granatum L./genotoxicidade Punica granatum L./análise cromatográfica Plantas medicinais Romã

Übergeordnetes Werk:	In: Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo, 2010, 51(2015), 1, Seite 241-248
Übergeordnetes Werk:	volume:51 ; year:2015 ; number:1 ; pages:241-248

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1590/S1984-82502015000100024

Katalog-ID:	DOAJ048802352

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callnumber-first	R - Medicine
author	Andrielle Wouters Kuhn
spellingShingle	Andrielle Wouters Kuhn misc RS1-441 misc Punica granatum L./fitoquímica misc Punica granatum L./genotoxicidade misc Punica granatum L./análise cromatográfica misc Plantas medicinais misc Romã misc Pharmacy and materia medica Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test
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topic_title	RS1-441 Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test Punica granatum L./fitoquímica Punica granatum L./genotoxicidade Punica granatum L./análise cromatográfica Plantas medicinais Romã
topic	misc RS1-441 misc Punica granatum L./fitoquímica misc Punica granatum L./genotoxicidade misc Punica granatum L./análise cromatográfica misc Plantas medicinais misc Romã misc Pharmacy and materia medica
topic_unstemmed	misc RS1-441 misc Punica granatum L./fitoquímica misc Punica granatum L./genotoxicidade misc Punica granatum L./análise cromatográfica misc Plantas medicinais misc Romã misc Pharmacy and materia medica
topic_browse	misc RS1-441 misc Punica granatum L./fitoquímica misc Punica granatum L./genotoxicidade misc Punica granatum L./análise cromatográfica misc Plantas medicinais misc Romã misc Pharmacy and materia medica
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title	Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test
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title_full	Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test
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title_sort	chromatographic analysis and antiproliferative potential of aqueous extracts of punica granatum fruit peels using the allium cepa test
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title_auth	Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test
abstract	Punica granatum L., locally known as romanzeira, is native to Asia but found throughout Brazil. P. granatum is used for treating inflammatory, infectious and respiratory diseases. The aim of this study was to evaluate the chromatography and genotoxicity of an aqueous extract of P. granatum (pomegranate) fruit peel using the Allium cepa L. test. The experiment set-up entailed 7 treatments: T1-distilled water, T2-tea 5 g.L-1, T3-tea 10 g.L-1, T4-glyphosate at 9.6%, T5-glyphosate with subsequent recovery in distilled water, T6-glyphosate with subsequent recovery in tea 5 g.L-1 and T7-glyphosate with subsequent recovery in tea 10 g.L-1. The rootlets were collected and fixed in ethanol:acetic acid (3:1) for 24 hours, then stored in 70% ethanol under refrigeration. Analysis was performed using high performance liquid chromatography for the quantification of the extracted phenolic compounds. Gallic acid, catechin, caffeic acid, and rutin were abundant in the extracts of P. granatum. The extracts were found to exhibit antiproliferative potential but not antimutagenic or genotoxic activity.
abstractGer	Punica granatum L., locally known as romanzeira, is native to Asia but found throughout Brazil. P. granatum is used for treating inflammatory, infectious and respiratory diseases. The aim of this study was to evaluate the chromatography and genotoxicity of an aqueous extract of P. granatum (pomegranate) fruit peel using the Allium cepa L. test. The experiment set-up entailed 7 treatments: T1-distilled water, T2-tea 5 g.L-1, T3-tea 10 g.L-1, T4-glyphosate at 9.6%, T5-glyphosate with subsequent recovery in distilled water, T6-glyphosate with subsequent recovery in tea 5 g.L-1 and T7-glyphosate with subsequent recovery in tea 10 g.L-1. The rootlets were collected and fixed in ethanol:acetic acid (3:1) for 24 hours, then stored in 70% ethanol under refrigeration. Analysis was performed using high performance liquid chromatography for the quantification of the extracted phenolic compounds. Gallic acid, catechin, caffeic acid, and rutin were abundant in the extracts of P. granatum. The extracts were found to exhibit antiproliferative potential but not antimutagenic or genotoxic activity.
abstract_unstemmed	Punica granatum L., locally known as romanzeira, is native to Asia but found throughout Brazil. P. granatum is used for treating inflammatory, infectious and respiratory diseases. The aim of this study was to evaluate the chromatography and genotoxicity of an aqueous extract of P. granatum (pomegranate) fruit peel using the Allium cepa L. test. The experiment set-up entailed 7 treatments: T1-distilled water, T2-tea 5 g.L-1, T3-tea 10 g.L-1, T4-glyphosate at 9.6%, T5-glyphosate with subsequent recovery in distilled water, T6-glyphosate with subsequent recovery in tea 5 g.L-1 and T7-glyphosate with subsequent recovery in tea 10 g.L-1. The rootlets were collected and fixed in ethanol:acetic acid (3:1) for 24 hours, then stored in 70% ethanol under refrigeration. Analysis was performed using high performance liquid chromatography for the quantification of the extracted phenolic compounds. Gallic acid, catechin, caffeic acid, and rutin were abundant in the extracts of P. granatum. The extracts were found to exhibit antiproliferative potential but not antimutagenic or genotoxic activity.
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title_short	Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test
url	https://doi.org/10.1590/S1984-82502015000100024 https://doaj.org/article/ce3d71f247c1407faa524d1d562cbc10 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100241&lng=en&tlng=en https://doaj.org/toc/2175-9790
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up_date	2024-07-03T19:46:13.642Z
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P. granatum is used for treating inflammatory, infectious and respiratory diseases. The aim of this study was to evaluate the chromatography and genotoxicity of an aqueous extract of P. granatum (pomegranate) fruit peel using the Allium cepa L. test. The experiment set-up entailed 7 treatments: T1-distilled water, T2-tea 5 g.L-1, T3-tea 10 g.L-1, T4-glyphosate at 9.6%, T5-glyphosate with subsequent recovery in distilled water, T6-glyphosate with subsequent recovery in tea 5 g.L-1 and T7-glyphosate with subsequent recovery in tea 10 g.L-1. The rootlets were collected and fixed in ethanol:acetic acid (3:1) for 24 hours, then stored in 70% ethanol under refrigeration. Analysis was performed using high performance liquid chromatography for the quantification of the extracted phenolic compounds. Gallic acid, catechin, caffeic acid, and rutin were abundant in the extracts of P. granatum. 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Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test

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