Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)

Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze g...
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Gespeichert in:

Autor*in:	Andrielle Wouters Kuhn [verfasserIn] Marília Tedesco [verfasserIn] Aline Augusti Boligon [verfasserIn] Viviane Dal-Souto Frescura [verfasserIn] Margareth Linde Athayde [verfasserIn] Solange Bosio Tedesco [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	P. longipes/efeito antiproliferativo P. longipes/potencial genotóxico P. longipes/análise cromatográfica Teste de Allium cepa/genotoxicidade

Übergeordnetes Werk:	In: Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo, 2010, 51(2015), 3, Seite 533-540
Übergeordnetes Werk:	volume:51 ; year:2015 ; number:3 ; pages:533-540

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1590/S1984-82502015000300005

Katalog-ID:	DOAJ049556487

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spelling	10.1590/S1984-82502015000300005 doi (DE-627)DOAJ049556487 (DE-599)DOAJc3c2d124e30e4e72a5b23463348896bd DE-627 ger DE-627 rakwb eng RS1-441 Andrielle Wouters Kuhn verfasserin aut Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo) 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. Only extracts from the Santa Maria sample exhibited genotoxic potential. P. longipes/efeito antiproliferativo P. longipes/potencial genotóxico P. longipes/análise cromatográfica Teste de Allium cepa/genotoxicidade Pharmacy and materia medica Marília Tedesco verfasserin aut Aline Augusti Boligon verfasserin aut Viviane Dal-Souto Frescura verfasserin aut Margareth Linde Athayde verfasserin aut Solange Bosio Tedesco verfasserin aut In Brazilian Journal of Pharmaceutical Sciences Universidade de São Paulo, 2010 51(2015), 3, Seite 533-540 (DE-627)72781057X (DE-600)2685807-1 21759790 nnns volume:51 year:2015 number:3 pages:533-540 https://doi.org/10.1590/S1984-82502015000300005 kostenfrei https://doaj.org/article/c3c2d124e30e4e72a5b23463348896bd kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300533&lng=en&tlng=en kostenfrei https://doaj.org/toc/2175-9790 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 51 2015 3 533-540
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allfieldsGer	10.1590/S1984-82502015000300005 doi (DE-627)DOAJ049556487 (DE-599)DOAJc3c2d124e30e4e72a5b23463348896bd DE-627 ger DE-627 rakwb eng RS1-441 Andrielle Wouters Kuhn verfasserin aut Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo) 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. Only extracts from the Santa Maria sample exhibited genotoxic potential. P. longipes/efeito antiproliferativo P. longipes/potencial genotóxico P. longipes/análise cromatográfica Teste de Allium cepa/genotoxicidade Pharmacy and materia medica Marília Tedesco verfasserin aut Aline Augusti Boligon verfasserin aut Viviane Dal-Souto Frescura verfasserin aut Margareth Linde Athayde verfasserin aut Solange Bosio Tedesco verfasserin aut In Brazilian Journal of Pharmaceutical Sciences Universidade de São Paulo, 2010 51(2015), 3, Seite 533-540 (DE-627)72781057X (DE-600)2685807-1 21759790 nnns volume:51 year:2015 number:3 pages:533-540 https://doi.org/10.1590/S1984-82502015000300005 kostenfrei https://doaj.org/article/c3c2d124e30e4e72a5b23463348896bd kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300533&lng=en&tlng=en kostenfrei https://doaj.org/toc/2175-9790 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 51 2015 3 533-540
allfieldsSound	10.1590/S1984-82502015000300005 doi (DE-627)DOAJ049556487 (DE-599)DOAJc3c2d124e30e4e72a5b23463348896bd DE-627 ger DE-627 rakwb eng RS1-441 Andrielle Wouters Kuhn verfasserin aut Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo) 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. Only extracts from the Santa Maria sample exhibited genotoxic potential. P. longipes/efeito antiproliferativo P. longipes/potencial genotóxico P. longipes/análise cromatográfica Teste de Allium cepa/genotoxicidade Pharmacy and materia medica Marília Tedesco verfasserin aut Aline Augusti Boligon verfasserin aut Viviane Dal-Souto Frescura verfasserin aut Margareth Linde Athayde verfasserin aut Solange Bosio Tedesco verfasserin aut In Brazilian Journal of Pharmaceutical Sciences Universidade de São Paulo, 2010 51(2015), 3, Seite 533-540 (DE-627)72781057X (DE-600)2685807-1 21759790 nnns volume:51 year:2015 number:3 pages:533-540 https://doi.org/10.1590/S1984-82502015000300005 kostenfrei https://doaj.org/article/c3c2d124e30e4e72a5b23463348896bd kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300533&lng=en&tlng=en kostenfrei https://doaj.org/toc/2175-9790 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 51 2015 3 533-540
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callnumber-first	R - Medicine
author	Andrielle Wouters Kuhn
spellingShingle	Andrielle Wouters Kuhn misc RS1-441 misc P. longipes/efeito antiproliferativo misc P. longipes/potencial genotóxico misc P. longipes/análise cromatográfica misc Teste de Allium cepa/genotoxicidade misc Pharmacy and materia medica Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)
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topic_title	RS1-441 Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo) P. longipes/efeito antiproliferativo P. longipes/potencial genotóxico P. longipes/análise cromatográfica Teste de Allium cepa/genotoxicidade
topic	misc RS1-441 misc P. longipes/efeito antiproliferativo misc P. longipes/potencial genotóxico misc P. longipes/análise cromatográfica misc Teste de Allium cepa/genotoxicidade misc Pharmacy and materia medica
topic_unstemmed	misc RS1-441 misc P. longipes/efeito antiproliferativo misc P. longipes/potencial genotóxico misc P. longipes/análise cromatográfica misc Teste de Allium cepa/genotoxicidade misc Pharmacy and materia medica
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title	Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)
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title_full	Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)
author_sort	Andrielle Wouters Kuhn
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title_sort	genotoxic and chromatographic analyses of aqueous extracts of peltodon longipes kunth ex benth. (hortelã-do-campo)
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title_auth	Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)
abstract	Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. Only extracts from the Santa Maria sample exhibited genotoxic potential.
abstractGer	Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. Only extracts from the Santa Maria sample exhibited genotoxic potential.
abstract_unstemmed	Peltodon longipes is used as a stimulant and emmenagogue. The objective of this study was to perform genotoxic and chromatographic analyses of the extracts of two samples of P. longipes, collected from the cities of Santa Maria and Tupanciretã, RS, Brazil. The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. Only extracts from the Santa Maria sample exhibited genotoxic potential.
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title_short	Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)
url	https://doi.org/10.1590/S1984-82502015000300005 https://doaj.org/article/c3c2d124e30e4e72a5b23463348896bd http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300533&lng=en&tlng=en https://doaj.org/toc/2175-9790
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up_date	2024-07-03T23:52:06.436Z
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The Allium cepa assay was used to analyze genotoxicity while high-performance liquid chromatography was employed to determine phenolic compounds. The genotoxicity experiment consisted of nine groups each comprising four A. cepa bulbs. Bulb roots were developed in distilled water and then transferred for the treatments, for 24 hours, and the negative control remained in water. The treatments were: aqueous extracts at concentrations of 5 and 15 g L-1 for each sample, plus four groups treated with 1% glyphosate, one of which was used as a positive control and the other three for testing DNA damage recovery using water and the extracts of P. longipes from Santa Maria. All extracts of P. longipes exhibited anti-proliferative potential, although the effect was significantly greater for the extracts from the Tupanciretã sample. This sample also contained the highest amount of rosmarinic acid and kaempferol, which may confer the effects found in these extracts. 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Genotoxic and chromatographic analyses of aqueous extracts of Peltodon longipes Kunth ex Benth. (hortelã-do-campo)

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