CD11c immunopositive cells in the human fetal vermiform appendix

Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. T...
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Autor*in:	Radenković Goran [verfasserIn] Petrović Vladimir [verfasserIn] Nedin-Ranković Gorana [verfasserIn] Denčić Tijana [verfasserIn] Živković Vladimir [verfasserIn] Jocić Miodrag [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch ; srp

Erschienen:	2021

Schlagwörter:	fetus appendix dendritic cells leukocytes biomarkers antigens cd11

Übergeordnetes Werk:	In: Vojnosanitetski Pregled - Military Health Department, Ministry of Defance, Serbia, 2012, 78(2021), 8, Seite 882-886
Übergeordnetes Werk:	volume:78 ; year:2021 ; number:8 ; pages:882-886

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.2298/VSP191126148R

Katalog-ID:	DOAJ05079860X

Internformat


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520			\|a Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration.
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700	0		\|a Petrović Vladimir \|e verfasserin \|4 aut
700	0		\|a Nedin-Ranković Gorana \|e verfasserin \|4 aut
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700	0		\|a Živković Vladimir \|e verfasserin \|4 aut
700	0		\|a Jocić Miodrag \|e verfasserin \|4 aut
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912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
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912			\|a GBV_ILN_2190
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912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
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allfields	10.2298/VSP191126148R doi (DE-627)DOAJ05079860X (DE-599)DOAJc3a8b18018454135abc0ff04aa1a31c7 DE-627 ger DE-627 rakwb eng srp R5-920 Radenković Goran verfasserin aut CD11c immunopositive cells in the human fetal vermiform appendix 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration. fetus appendix dendritic cells leukocytes biomarkers antigens cd11 Medicine (General) Petrović Vladimir verfasserin aut Nedin-Ranković Gorana verfasserin aut Denčić Tijana verfasserin aut Živković Vladimir verfasserin aut Jocić Miodrag verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 78(2021), 8, Seite 882-886 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:78 year:2021 number:8 pages:882-886 https://doi.org/10.2298/VSP191126148R kostenfrei https://doaj.org/article/c3a8b18018454135abc0ff04aa1a31c7 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900148R.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 78 2021 8 882-886
spelling	10.2298/VSP191126148R doi (DE-627)DOAJ05079860X (DE-599)DOAJc3a8b18018454135abc0ff04aa1a31c7 DE-627 ger DE-627 rakwb eng srp R5-920 Radenković Goran verfasserin aut CD11c immunopositive cells in the human fetal vermiform appendix 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration. fetus appendix dendritic cells leukocytes biomarkers antigens cd11 Medicine (General) Petrović Vladimir verfasserin aut Nedin-Ranković Gorana verfasserin aut Denčić Tijana verfasserin aut Živković Vladimir verfasserin aut Jocić Miodrag verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 78(2021), 8, Seite 882-886 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:78 year:2021 number:8 pages:882-886 https://doi.org/10.2298/VSP191126148R kostenfrei https://doaj.org/article/c3a8b18018454135abc0ff04aa1a31c7 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900148R.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 78 2021 8 882-886
allfields_unstemmed	10.2298/VSP191126148R doi (DE-627)DOAJ05079860X (DE-599)DOAJc3a8b18018454135abc0ff04aa1a31c7 DE-627 ger DE-627 rakwb eng srp R5-920 Radenković Goran verfasserin aut CD11c immunopositive cells in the human fetal vermiform appendix 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration. fetus appendix dendritic cells leukocytes biomarkers antigens cd11 Medicine (General) Petrović Vladimir verfasserin aut Nedin-Ranković Gorana verfasserin aut Denčić Tijana verfasserin aut Živković Vladimir verfasserin aut Jocić Miodrag verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 78(2021), 8, Seite 882-886 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:78 year:2021 number:8 pages:882-886 https://doi.org/10.2298/VSP191126148R kostenfrei https://doaj.org/article/c3a8b18018454135abc0ff04aa1a31c7 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900148R.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 78 2021 8 882-886
allfieldsGer	10.2298/VSP191126148R doi (DE-627)DOAJ05079860X (DE-599)DOAJc3a8b18018454135abc0ff04aa1a31c7 DE-627 ger DE-627 rakwb eng srp R5-920 Radenković Goran verfasserin aut CD11c immunopositive cells in the human fetal vermiform appendix 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration. fetus appendix dendritic cells leukocytes biomarkers antigens cd11 Medicine (General) Petrović Vladimir verfasserin aut Nedin-Ranković Gorana verfasserin aut Denčić Tijana verfasserin aut Živković Vladimir verfasserin aut Jocić Miodrag verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 78(2021), 8, Seite 882-886 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:78 year:2021 number:8 pages:882-886 https://doi.org/10.2298/VSP191126148R kostenfrei https://doaj.org/article/c3a8b18018454135abc0ff04aa1a31c7 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900148R.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 78 2021 8 882-886
allfieldsSound	10.2298/VSP191126148R doi (DE-627)DOAJ05079860X (DE-599)DOAJc3a8b18018454135abc0ff04aa1a31c7 DE-627 ger DE-627 rakwb eng srp R5-920 Radenković Goran verfasserin aut CD11c immunopositive cells in the human fetal vermiform appendix 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration. fetus appendix dendritic cells leukocytes biomarkers antigens cd11 Medicine (General) Petrović Vladimir verfasserin aut Nedin-Ranković Gorana verfasserin aut Denčić Tijana verfasserin aut Živković Vladimir verfasserin aut Jocić Miodrag verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 78(2021), 8, Seite 882-886 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:78 year:2021 number:8 pages:882-886 https://doi.org/10.2298/VSP191126148R kostenfrei https://doaj.org/article/c3a8b18018454135abc0ff04aa1a31c7 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900148R.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 78 2021 8 882-886
language	English
source	In Vojnosanitetski Pregled 78(2021), 8, Seite 882-886 volume:78 year:2021 number:8 pages:882-886
sourceStr	In Vojnosanitetski Pregled 78(2021), 8, Seite 882-886 volume:78 year:2021 number:8 pages:882-886
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	fetus appendix dendritic cells leukocytes biomarkers antigens cd11 Medicine (General)
isfreeaccess_bool	true
container_title	Vojnosanitetski Pregled
authorswithroles_txt_mv	Radenković Goran @@aut@@ Petrović Vladimir @@aut@@ Nedin-Ranković Gorana @@aut@@ Denčić Tijana @@aut@@ Živković Vladimir @@aut@@ Jocić Miodrag @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	474382613
id	DOAJ05079860X
language_de	englisch
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A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. 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callnumber-first	R - Medicine
author	Radenković Goran
spellingShingle	Radenković Goran misc R5-920 misc fetus misc appendix misc dendritic cells misc leukocytes misc biomarkers misc antigens misc cd11 misc Medicine (General) CD11c immunopositive cells in the human fetal vermiform appendix
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topic_title	R5-920 CD11c immunopositive cells in the human fetal vermiform appendix fetus appendix dendritic cells leukocytes biomarkers antigens cd11
topic	misc R5-920 misc fetus misc appendix misc dendritic cells misc leukocytes misc biomarkers misc antigens misc cd11 misc Medicine (General)
topic_unstemmed	misc R5-920 misc fetus misc appendix misc dendritic cells misc leukocytes misc biomarkers misc antigens misc cd11 misc Medicine (General)
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title	CD11c immunopositive cells in the human fetal vermiform appendix
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title_full	CD11c immunopositive cells in the human fetal vermiform appendix
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author_browse	Radenković Goran Petrović Vladimir Nedin-Ranković Gorana Denčić Tijana Živković Vladimir Jocić Miodrag
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title_sort	cd11c immunopositive cells in the human fetal vermiform appendix
callnumber	R5-920
title_auth	CD11c immunopositive cells in the human fetal vermiform appendix
abstract	Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration.
abstractGer	Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration.
abstract_unstemmed	Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora. It also has a role in the normal development of gut-associated lymphatic tissue. The aim of this study was to examine the distribution of dendritic cell marker C D11c in the human fetal vermiform appendix from the 13th to the 23rd week of development. Methods. The material in this study consisted of 28 human fetal vermiform appendixes from the 13th to the 23rd week of gestagion. The tissue samples were routinely processed to obtain paraffin blocks, and 5 μm thick tissue sections were stained with hematoxylin and eosin, and with rabbit monoclonal antibody against CD11c antigen and mouse monoclonal antibody against desmin. Results. The first CD11c immunopositive cells appear in the 14th week of development. They are present in the mucosa/submucosa and are interconnected via their cytoplasmic processes. Around these cells, a small number of lymphocytes can be seen. The first lymphoid aggregations appear in the 16th week of development, and lymphocytes are organized around the network made of CD11c immunopositive cells. From the 18th week of development, the lymphoid aggregations are organized in the form of primary lymphoid follicles, containing an extensive network made of CD11c immunopositive cells. Conclusion. CD11c immunopositive cells appear first in the process of primary lymphoid follicle generation and have a role in forming a lattice which will serve as the basis for lymphocyte migration.
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title_short	CD11c immunopositive cells in the human fetal vermiform appendix
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CD11c immunopositive cells in the human fetal vermiform appendix

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