Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity

It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Yue-Chiun Li [verfasserIn] Nguyen Thi Ngan [verfasserIn] Kun-Ching Cheng [verfasserIn] Tsong-Long Hwang [verfasserIn] Tran Dinh Thang [verfasserIn] Nguyen Ngoc Tuan [verfasserIn] Mei-Lin Yang [verfasserIn] Ping-Chung Kuo [verfasserIn] Tian-Shung Wu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	anti-inflammatory superoxide anion generation elastase release

Übergeordnetes Werk:	In: Molecules - MDPI AG, 2003, 26(2021), 23, p 7311
Übergeordnetes Werk:	volume:26 ; year:2021 ; number:23, p 7311

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/molecules26237311

Katalog-ID:	DOAJ051473259

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ051473259
003	DE-627
005	20240412130315.0
007	cr uuu---uuuuu
008	230227s2021 xx \|\|\|\|\|o 00\| \|\|eng c
024	7		\|a 10.3390/molecules26237311 \|2 doi
035			\|a (DE-627)DOAJ051473259
035			\|a (DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
050		0	\|a QD241-441
100	0		\|a Yue-Chiun Li \|e verfasserin \|4 aut
245	1	0	\|a Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity
264		1	\|c 2021
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods.
650		4	\|a <i<Trametes cubensis</i<
650		4	\|a <i<Trametes suaveolens</i<
650		4	\|a anti-inflammatory
650		4	\|a superoxide anion generation
650		4	\|a elastase release
653		0	\|a Organic chemistry
700	0		\|a Nguyen Thi Ngan \|e verfasserin \|4 aut
700	0		\|a Kun-Ching Cheng \|e verfasserin \|4 aut
700	0		\|a Tsong-Long Hwang \|e verfasserin \|4 aut
700	0		\|a Tran Dinh Thang \|e verfasserin \|4 aut
700	0		\|a Nguyen Ngoc Tuan \|e verfasserin \|4 aut
700	0		\|a Mei-Lin Yang \|e verfasserin \|4 aut
700	0		\|a Ping-Chung Kuo \|e verfasserin \|4 aut
700	0		\|a Tian-Shung Wu \|e verfasserin \|4 aut
773	0	8	\|i In \|t Molecules \|d MDPI AG, 2003 \|g 26(2021), 23, p 7311 \|w (DE-627)311313132 \|w (DE-600)2008644-1 \|x 14203049 \|7 nnns
773	1	8	\|g volume:26 \|g year:2021 \|g number:23, p 7311
856	4	0	\|u https://doi.org/10.3390/molecules26237311 \|z kostenfrei
856	4	0	\|u https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925 \|z kostenfrei
856	4	0	\|u https://www.mdpi.com/1420-3049/26/23/7311 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1420-3049 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 26 \|j 2021 \|e 23, p 7311

Indexfelder

author_variant	y c l ycl n t n ntn k c c kcc t l h tlh t d t tdt n n t nnt m l y mly p c k pck t s w tsw
matchkey_str	article:14203049:2021----::osiunsrmhfutnbdeoirmtsuessadtaeesaelninitaadh
hierarchy_sort_str	2021
callnumber-subject-code	QD
publishDate	2021
allfields	10.3390/molecules26237311 doi (DE-627)DOAJ051473259 (DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925 DE-627 ger DE-627 rakwb eng QD241-441 Yue-Chiun Li verfasserin aut Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods. <i<Trametes cubensis</i< <i<Trametes suaveolens</i< anti-inflammatory superoxide anion generation elastase release Organic chemistry Nguyen Thi Ngan verfasserin aut Kun-Ching Cheng verfasserin aut Tsong-Long Hwang verfasserin aut Tran Dinh Thang verfasserin aut Nguyen Ngoc Tuan verfasserin aut Mei-Lin Yang verfasserin aut Ping-Chung Kuo verfasserin aut Tian-Shung Wu verfasserin aut In Molecules MDPI AG, 2003 26(2021), 23, p 7311 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:26 year:2021 number:23, p 7311 https://doi.org/10.3390/molecules26237311 kostenfrei https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925 kostenfrei https://www.mdpi.com/1420-3049/26/23/7311 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2021 23, p 7311
spelling	10.3390/molecules26237311 doi (DE-627)DOAJ051473259 (DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925 DE-627 ger DE-627 rakwb eng QD241-441 Yue-Chiun Li verfasserin aut Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods. <i<Trametes cubensis</i< <i<Trametes suaveolens</i< anti-inflammatory superoxide anion generation elastase release Organic chemistry Nguyen Thi Ngan verfasserin aut Kun-Ching Cheng verfasserin aut Tsong-Long Hwang verfasserin aut Tran Dinh Thang verfasserin aut Nguyen Ngoc Tuan verfasserin aut Mei-Lin Yang verfasserin aut Ping-Chung Kuo verfasserin aut Tian-Shung Wu verfasserin aut In Molecules MDPI AG, 2003 26(2021), 23, p 7311 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:26 year:2021 number:23, p 7311 https://doi.org/10.3390/molecules26237311 kostenfrei https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925 kostenfrei https://www.mdpi.com/1420-3049/26/23/7311 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2021 23, p 7311
allfields_unstemmed	10.3390/molecules26237311 doi (DE-627)DOAJ051473259 (DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925 DE-627 ger DE-627 rakwb eng QD241-441 Yue-Chiun Li verfasserin aut Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods. <i<Trametes cubensis</i< <i<Trametes suaveolens</i< anti-inflammatory superoxide anion generation elastase release Organic chemistry Nguyen Thi Ngan verfasserin aut Kun-Ching Cheng verfasserin aut Tsong-Long Hwang verfasserin aut Tran Dinh Thang verfasserin aut Nguyen Ngoc Tuan verfasserin aut Mei-Lin Yang verfasserin aut Ping-Chung Kuo verfasserin aut Tian-Shung Wu verfasserin aut In Molecules MDPI AG, 2003 26(2021), 23, p 7311 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:26 year:2021 number:23, p 7311 https://doi.org/10.3390/molecules26237311 kostenfrei https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925 kostenfrei https://www.mdpi.com/1420-3049/26/23/7311 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2021 23, p 7311
allfieldsGer	10.3390/molecules26237311 doi (DE-627)DOAJ051473259 (DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925 DE-627 ger DE-627 rakwb eng QD241-441 Yue-Chiun Li verfasserin aut Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods. <i<Trametes cubensis</i< <i<Trametes suaveolens</i< anti-inflammatory superoxide anion generation elastase release Organic chemistry Nguyen Thi Ngan verfasserin aut Kun-Ching Cheng verfasserin aut Tsong-Long Hwang verfasserin aut Tran Dinh Thang verfasserin aut Nguyen Ngoc Tuan verfasserin aut Mei-Lin Yang verfasserin aut Ping-Chung Kuo verfasserin aut Tian-Shung Wu verfasserin aut In Molecules MDPI AG, 2003 26(2021), 23, p 7311 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:26 year:2021 number:23, p 7311 https://doi.org/10.3390/molecules26237311 kostenfrei https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925 kostenfrei https://www.mdpi.com/1420-3049/26/23/7311 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2021 23, p 7311
allfieldsSound	10.3390/molecules26237311 doi (DE-627)DOAJ051473259 (DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925 DE-627 ger DE-627 rakwb eng QD241-441 Yue-Chiun Li verfasserin aut Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods. <i<Trametes cubensis</i< <i<Trametes suaveolens</i< anti-inflammatory superoxide anion generation elastase release Organic chemistry Nguyen Thi Ngan verfasserin aut Kun-Ching Cheng verfasserin aut Tsong-Long Hwang verfasserin aut Tran Dinh Thang verfasserin aut Nguyen Ngoc Tuan verfasserin aut Mei-Lin Yang verfasserin aut Ping-Chung Kuo verfasserin aut Tian-Shung Wu verfasserin aut In Molecules MDPI AG, 2003 26(2021), 23, p 7311 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:26 year:2021 number:23, p 7311 https://doi.org/10.3390/molecules26237311 kostenfrei https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925 kostenfrei https://www.mdpi.com/1420-3049/26/23/7311 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2021 23, p 7311
language	English
source	In Molecules 26(2021), 23, p 7311 volume:26 year:2021 number:23, p 7311
sourceStr	In Molecules 26(2021), 23, p 7311 volume:26 year:2021 number:23, p 7311
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	<i<Trametes cubensis</i< <i<Trametes suaveolens</i< anti-inflammatory superoxide anion generation elastase release Organic chemistry
isfreeaccess_bool	true
container_title	Molecules
authorswithroles_txt_mv	Yue-Chiun Li @@aut@@ Nguyen Thi Ngan @@aut@@ Kun-Ching Cheng @@aut@@ Tsong-Long Hwang @@aut@@ Tran Dinh Thang @@aut@@ Nguyen Ngoc Tuan @@aut@@ Mei-Lin Yang @@aut@@ Ping-Chung Kuo @@aut@@ Tian-Shung Wu @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	311313132
id	DOAJ051473259
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ051473259</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240412130315.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230227s2021 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/molecules26237311</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ051473259</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QD241-441</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Yue-Chiun Li</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a"><i<Trametes cubensis</i<</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a"><i<Trametes suaveolens</i<</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">anti-inflammatory</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">superoxide anion generation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">elastase release</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Organic chemistry</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nguyen Thi Ngan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kun-Ching Cheng</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tsong-Long Hwang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tran Dinh Thang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nguyen Ngoc Tuan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mei-Lin Yang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ping-Chung Kuo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tian-Shung Wu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Molecules</subfield><subfield code="d">MDPI AG, 2003</subfield><subfield code="g">26(2021), 23, p 7311</subfield><subfield code="w">(DE-627)311313132</subfield><subfield code="w">(DE-600)2008644-1</subfield><subfield code="x">14203049</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:26</subfield><subfield code="g">year:2021</subfield><subfield code="g">number:23, p 7311</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/molecules26237311</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/1420-3049/26/23/7311</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1420-3049</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">26</subfield><subfield code="j">2021</subfield><subfield code="e">23, p 7311</subfield></datafield></record></collection>
callnumber-first	Q - Science
author	Yue-Chiun Li
spellingShingle	Yue-Chiun Li misc QD241-441 misc <i<Trametes cubensis</i< misc <i<Trametes suaveolens</i< misc anti-inflammatory misc superoxide anion generation misc elastase release misc Organic chemistry Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity
authorStr	Yue-Chiun Li
ppnlink_with_tag_str_mv	@@773@@(DE-627)311313132
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	QD241-441
illustrated	Not Illustrated
issn	14203049
topic_title	QD241-441 Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity <i<Trametes cubensis</i< <i<Trametes suaveolens</i< anti-inflammatory superoxide anion generation elastase release
topic	misc QD241-441 misc <i<Trametes cubensis</i< misc <i<Trametes suaveolens</i< misc anti-inflammatory misc superoxide anion generation misc elastase release misc Organic chemistry
topic_unstemmed	misc QD241-441 misc <i<Trametes cubensis</i< misc <i<Trametes suaveolens</i< misc anti-inflammatory misc superoxide anion generation misc elastase release misc Organic chemistry
topic_browse	misc QD241-441 misc <i<Trametes cubensis</i< misc <i<Trametes suaveolens</i< misc anti-inflammatory misc superoxide anion generation misc elastase release misc Organic chemistry
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Molecules
hierarchy_parent_id	311313132
hierarchy_top_title	Molecules
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)311313132 (DE-600)2008644-1
title	Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity
ctrlnum	(DE-627)DOAJ051473259 (DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925
title_full	Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity
author_sort	Yue-Chiun Li
journal	Molecules
journalStr	Molecules
callnumber-first-code	Q
lang_code	eng
isOA_bool	true
recordtype	marc
publishDateSort	2021
contenttype_str_mv	txt
author_browse	Yue-Chiun Li Nguyen Thi Ngan Kun-Ching Cheng Tsong-Long Hwang Tran Dinh Thang Nguyen Ngoc Tuan Mei-Lin Yang Ping-Chung Kuo Tian-Shung Wu
container_volume	26
class	QD241-441
format_se	Elektronische Aufsätze
author-letter	Yue-Chiun Li
doi_str_mv	10.3390/molecules26237311
author2-role	verfasserin
title_sort	constituents from the fruiting bodies of <i<trametes cubensis</i< and <i<trametes suaveolens</i< in vietnam and their anti-inflammatory bioactivity
callnumber	QD241-441
title_auth	Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity
abstract	It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods.
abstractGer	It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods.
abstract_unstemmed	It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	23, p 7311
title_short	Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity
url	https://doi.org/10.3390/molecules26237311 https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925 https://www.mdpi.com/1420-3049/26/23/7311 https://doaj.org/toc/1420-3049
remote_bool	true
author2	Nguyen Thi Ngan Kun-Ching Cheng Tsong-Long Hwang Tran Dinh Thang Nguyen Ngoc Tuan Mei-Lin Yang Ping-Chung Kuo Tian-Shung Wu
author2Str	Nguyen Thi Ngan Kun-Ching Cheng Tsong-Long Hwang Tran Dinh Thang Nguyen Ngoc Tuan Mei-Lin Yang Ping-Chung Kuo Tian-Shung Wu
ppnlink	311313132
callnumber-subject	QD - Chemistry
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.3390/molecules26237311
callnumber-a	QD241-441
up_date	2024-07-03T20:33:22.053Z
_version_	1803591406903623680
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ051473259</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240412130315.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230227s2021 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/molecules26237311</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ051473259</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ5cdcb596dd1349e7b352d41ca7628925</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QD241-441</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Yue-Chiun Li</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">It is reported that various fungi have been used for medicine and edible foods. The tropical <i<Trametes</i< genus is popular and well-known in Vietnam for its health effects and bioactivities. In this study, the fruiting bodies of the edible fungi <i<T. cubensis</i< and <i<T. suaveolens</i< were collected in Vietnam. The preliminary bioactivity screening data indicated that the methanol extracts of the fruiting bodies of <i<T. cubensis</i< and <i<T. suaveolens</i< displayed significant inhibition of superoxide anion generation and elastase release in human neutrophils. Therefore, the isolation and characterization were performed on these two species by a combination of chromatographic methods and spectrometric analysis. In total, twenty-four compounds were identified, and among these (<b<1–3</b<) were characterized by 1D-, 2D-NMR, and HRMS analytical data. In addition, the anti-inflammatory potentials of some purified compounds were examined by the cellular model for the inhibition of superoxide anion generation and elastase release in human neutrophils. Among the isolated compounds, (<b<5</b<,<b<14</b<), and (<b<19</b<) displayed significant anti-inflammatory potential. As the results suggest, the extracts and isolated compounds from <i<T. cubensis</i< and <i<T. suaveolens</i< are potential candidates for the further development of new anti-inflammatory lead drugs or natural healthy foods.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a"><i<Trametes cubensis</i<</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a"><i<Trametes suaveolens</i<</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">anti-inflammatory</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">superoxide anion generation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">elastase release</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Organic chemistry</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nguyen Thi Ngan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kun-Ching Cheng</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tsong-Long Hwang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tran Dinh Thang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nguyen Ngoc Tuan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mei-Lin Yang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ping-Chung Kuo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tian-Shung Wu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Molecules</subfield><subfield code="d">MDPI AG, 2003</subfield><subfield code="g">26(2021), 23, p 7311</subfield><subfield code="w">(DE-627)311313132</subfield><subfield code="w">(DE-600)2008644-1</subfield><subfield code="x">14203049</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:26</subfield><subfield code="g">year:2021</subfield><subfield code="g">number:23, p 7311</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/molecules26237311</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/5cdcb596dd1349e7b352d41ca7628925</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/1420-3049/26/23/7311</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1420-3049</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">26</subfield><subfield code="j">2021</subfield><subfield code="e">23, p 7311</subfield></datafield></record></collection>
score	7.40007

Nicht das Richtige dabei?

Schreiben Sie uns!

Constituents from the Fruiting Bodies of <i<Trametes cubensis</i< and <i<Trametes suaveolens</i< in Vietnam and Their Anti-Inflammatory Bioactivity

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?