Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era

Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends...
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Autor*in:	Gabby Elbaz-Greener [verfasserIn] Guy Rozen [verfasserIn] Fabio Kusniec [verfasserIn] Ibrahim Marai [verfasserIn] Shemy Carasso [verfasserIn] Dennis T. Ko [verfasserIn] Harindra C. Wijeysundera [verfasserIn] Ronny Alcalai [verfasserIn] David Planer [verfasserIn] Offer Amir [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis

Übergeordnetes Werk:	In: Frontiers in Cardiovascular Medicine - Frontiers Media S.A., 2015, 8(2021)
Übergeordnetes Werk:	volume:8 ; year:2021

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fcvm.2021.680123

Katalog-ID:	DOAJ051590646

Internformat


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520			\|a Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR.
650		4	\|a aortic valve replacement
650		4	\|a TAVR
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650		4	\|a surgical aortic valve implantation
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650		4	\|a aortic stenosis
653		0	\|a Diseases of the circulatory (Cardiovascular) system
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700	0		\|a Guy Rozen \|e verfasserin \|4 aut
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700	0		\|a Ibrahim Marai \|e verfasserin \|4 aut
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700	0		\|a Shemy Carasso \|e verfasserin \|4 aut
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700	0		\|a Dennis T. Ko \|e verfasserin \|4 aut
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allfields	10.3389/fcvm.2021.680123 doi (DE-627)DOAJ051590646 (DE-599)DOAJc5ce641f191c429484ada705fc483000 DE-627 ger DE-627 rakwb eng RC666-701 Gabby Elbaz-Greener verfasserin aut Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR. aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis Diseases of the circulatory (Cardiovascular) system Gabby Elbaz-Greener verfasserin aut Gabby Elbaz-Greener verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Fabio Kusniec verfasserin aut Fabio Kusniec verfasserin aut Ibrahim Marai verfasserin aut Ibrahim Marai verfasserin aut Shemy Carasso verfasserin aut Shemy Carasso verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Ronny Alcalai verfasserin aut David Planer verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut In Frontiers in Cardiovascular Medicine Frontiers Media S.A., 2015 8(2021) (DE-627)793951607 (DE-600)2781496-8 2297055X nnns volume:8 year:2021 https://doi.org/10.3389/fcvm.2021.680123 kostenfrei https://doaj.org/article/c5ce641f191c429484ada705fc483000 kostenfrei https://www.frontiersin.org/articles/10.3389/fcvm.2021.680123/full kostenfrei https://doaj.org/toc/2297-055X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021
spelling	10.3389/fcvm.2021.680123 doi (DE-627)DOAJ051590646 (DE-599)DOAJc5ce641f191c429484ada705fc483000 DE-627 ger DE-627 rakwb eng RC666-701 Gabby Elbaz-Greener verfasserin aut Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR. aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis Diseases of the circulatory (Cardiovascular) system Gabby Elbaz-Greener verfasserin aut Gabby Elbaz-Greener verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Fabio Kusniec verfasserin aut Fabio Kusniec verfasserin aut Ibrahim Marai verfasserin aut Ibrahim Marai verfasserin aut Shemy Carasso verfasserin aut Shemy Carasso verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Ronny Alcalai verfasserin aut David Planer verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut In Frontiers in Cardiovascular Medicine Frontiers Media S.A., 2015 8(2021) (DE-627)793951607 (DE-600)2781496-8 2297055X nnns volume:8 year:2021 https://doi.org/10.3389/fcvm.2021.680123 kostenfrei https://doaj.org/article/c5ce641f191c429484ada705fc483000 kostenfrei https://www.frontiersin.org/articles/10.3389/fcvm.2021.680123/full kostenfrei https://doaj.org/toc/2297-055X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021
allfields_unstemmed	10.3389/fcvm.2021.680123 doi (DE-627)DOAJ051590646 (DE-599)DOAJc5ce641f191c429484ada705fc483000 DE-627 ger DE-627 rakwb eng RC666-701 Gabby Elbaz-Greener verfasserin aut Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR. aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis Diseases of the circulatory (Cardiovascular) system Gabby Elbaz-Greener verfasserin aut Gabby Elbaz-Greener verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Fabio Kusniec verfasserin aut Fabio Kusniec verfasserin aut Ibrahim Marai verfasserin aut Ibrahim Marai verfasserin aut Shemy Carasso verfasserin aut Shemy Carasso verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Ronny Alcalai verfasserin aut David Planer verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut In Frontiers in Cardiovascular Medicine Frontiers Media S.A., 2015 8(2021) (DE-627)793951607 (DE-600)2781496-8 2297055X nnns volume:8 year:2021 https://doi.org/10.3389/fcvm.2021.680123 kostenfrei https://doaj.org/article/c5ce641f191c429484ada705fc483000 kostenfrei https://www.frontiersin.org/articles/10.3389/fcvm.2021.680123/full kostenfrei https://doaj.org/toc/2297-055X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021
allfieldsGer	10.3389/fcvm.2021.680123 doi (DE-627)DOAJ051590646 (DE-599)DOAJc5ce641f191c429484ada705fc483000 DE-627 ger DE-627 rakwb eng RC666-701 Gabby Elbaz-Greener verfasserin aut Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR. aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis Diseases of the circulatory (Cardiovascular) system Gabby Elbaz-Greener verfasserin aut Gabby Elbaz-Greener verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Fabio Kusniec verfasserin aut Fabio Kusniec verfasserin aut Ibrahim Marai verfasserin aut Ibrahim Marai verfasserin aut Shemy Carasso verfasserin aut Shemy Carasso verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Ronny Alcalai verfasserin aut David Planer verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut In Frontiers in Cardiovascular Medicine Frontiers Media S.A., 2015 8(2021) (DE-627)793951607 (DE-600)2781496-8 2297055X nnns volume:8 year:2021 https://doi.org/10.3389/fcvm.2021.680123 kostenfrei https://doaj.org/article/c5ce641f191c429484ada705fc483000 kostenfrei https://www.frontiersin.org/articles/10.3389/fcvm.2021.680123/full kostenfrei https://doaj.org/toc/2297-055X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021
allfieldsSound	10.3389/fcvm.2021.680123 doi (DE-627)DOAJ051590646 (DE-599)DOAJc5ce641f191c429484ada705fc483000 DE-627 ger DE-627 rakwb eng RC666-701 Gabby Elbaz-Greener verfasserin aut Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR. aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis Diseases of the circulatory (Cardiovascular) system Gabby Elbaz-Greener verfasserin aut Gabby Elbaz-Greener verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Guy Rozen verfasserin aut Fabio Kusniec verfasserin aut Fabio Kusniec verfasserin aut Ibrahim Marai verfasserin aut Ibrahim Marai verfasserin aut Shemy Carasso verfasserin aut Shemy Carasso verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Dennis T. Ko verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Harindra C. Wijeysundera verfasserin aut Ronny Alcalai verfasserin aut David Planer verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut Offer Amir verfasserin aut In Frontiers in Cardiovascular Medicine Frontiers Media S.A., 2015 8(2021) (DE-627)793951607 (DE-600)2781496-8 2297055X nnns volume:8 year:2021 https://doi.org/10.3389/fcvm.2021.680123 kostenfrei https://doaj.org/article/c5ce641f191c429484ada705fc483000 kostenfrei https://www.frontiersin.org/articles/10.3389/fcvm.2021.680123/full kostenfrei https://doaj.org/toc/2297-055X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021
language	English
source	In Frontiers in Cardiovascular Medicine 8(2021) volume:8 year:2021
sourceStr	In Frontiers in Cardiovascular Medicine 8(2021) volume:8 year:2021
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis Diseases of the circulatory (Cardiovascular) system
isfreeaccess_bool	true
container_title	Frontiers in Cardiovascular Medicine
authorswithroles_txt_mv	Gabby Elbaz-Greener @@aut@@ Guy Rozen @@aut@@ Fabio Kusniec @@aut@@ Ibrahim Marai @@aut@@ Shemy Carasso @@aut@@ Dennis T. Ko @@aut@@ Harindra C. Wijeysundera @@aut@@ Ronny Alcalai @@aut@@ David Planer @@aut@@ Offer Amir @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	793951607
id	DOAJ051590646
language_de	englisch
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callnumber-first	R - Medicine
author	Gabby Elbaz-Greener
spellingShingle	Gabby Elbaz-Greener misc RC666-701 misc aortic valve replacement misc TAVR misc transcatheter and surgical aortic valve replacement misc surgical aortic valve implantation misc transcatheter aortic replacement misc aortic stenosis misc Diseases of the circulatory (Cardiovascular) system Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era
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topic_title	RC666-701 Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era aortic valve replacement TAVR transcatheter and surgical aortic valve replacement surgical aortic valve implantation transcatheter aortic replacement aortic stenosis
topic	misc RC666-701 misc aortic valve replacement misc TAVR misc transcatheter and surgical aortic valve replacement misc surgical aortic valve implantation misc transcatheter aortic replacement misc aortic stenosis misc Diseases of the circulatory (Cardiovascular) system
topic_unstemmed	misc RC666-701 misc aortic valve replacement misc TAVR misc transcatheter and surgical aortic valve replacement misc surgical aortic valve implantation misc transcatheter aortic replacement misc aortic stenosis misc Diseases of the circulatory (Cardiovascular) system
topic_browse	misc RC666-701 misc aortic valve replacement misc TAVR misc transcatheter and surgical aortic valve replacement misc surgical aortic valve implantation misc transcatheter aortic replacement misc aortic stenosis misc Diseases of the circulatory (Cardiovascular) system
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title	Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era
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title_full	Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era
author_sort	Gabby Elbaz-Greener
journal	Frontiers in Cardiovascular Medicine
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author_browse	Gabby Elbaz-Greener Guy Rozen Fabio Kusniec Ibrahim Marai Shemy Carasso Dennis T. Ko Harindra C. Wijeysundera Ronny Alcalai David Planer Offer Amir
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doi_str_mv	10.3389/fcvm.2021.680123
author2-role	verfasserin
title_sort	comparing trajectory of surgical aortic valve replacement in the early vs. late transcatheter aortic valve replacement era
callnumber	RC666-701
title_auth	Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era
abstract	Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR.
abstractGer	Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR.
abstract_unstemmed	Background: Traditionally, the only effective treatment for aortic stenosis was surgical aortic valve replacement (SAVR). Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011 and provided a critical alternative therapy. Our aims were to investigate the trends in the utilization of SAVR in the early vs. late TAVR era and to assess SAVR and TAVR outcomes.Methods: Using the 2011–2017 National Inpatient Sample database, we identified hospitalizations for patients with a most responsible diagnosis of aortic stenosis during which an aortic valve replacement (AVR) was performed, either SAVR or TAVR. Patients' sociodemographic and clinical characteristics, procedure complications, length of stay, and mortality were analyzed. Multivariable analyses were performed to identify predictors of in-hospital mortality. Piecewise regression analyses were performed to assess temporal trends in SAVR and TAVR utilization.Results: A total of 542,734 AVR procedures were analyzed. The utilization of SAVR was steady until 2014 with a significant downward trend in the following years 2015–2017 (P = 0.026). In contrast, a steady upward trend was observed in the TAVR procedure with a significant increase during the years 2015–2017 (P = 0.006). Higher in-hospital mortality was observed in SAVR patients. The mortality rate declined from 2011 to 2017 in a significantly higher proportion in the TAVR compared with the SAVR group.Conclusion: Utilization of SAVR showed a downward trend during the late TAVR era (2015–2017), and TAVR utilization demonstrated a steady upward trend during the years 2011–2017. Higher in-hospital mortality was recorded in patients who underwent SAVR.
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title_short	Comparing Trajectory of Surgical Aortic Valve Replacement in the Early vs. Late Transcatheter Aortic Valve Replacement Era
url	https://doi.org/10.3389/fcvm.2021.680123 https://doaj.org/article/c5ce641f191c429484ada705fc483000 https://www.frontiersin.org/articles/10.3389/fcvm.2021.680123/full https://doaj.org/toc/2297-055X
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author2	Gabby Elbaz-Greener Guy Rozen Fabio Kusniec Ibrahim Marai Shemy Carasso Dennis T. Ko Harindra C. Wijeysundera Ronny Alcalai David Planer Offer Amir
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up_date	2024-07-03T21:13:15.702Z
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