Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran
Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Sou...
Ausführliche Beschreibung
Autor*in: |
Miaad K Alkhudhairy [verfasserIn] Morteza Saki [verfasserIn] Sakineh Seyed–Mohammadi [verfasserIn] Nabi Jomehzadeh [verfasserIn] Saeed Khoshnood [verfasserIn] Mina Moradzadeh [verfasserIn] Sajjad Yazdansetad [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Übergeordnetes Werk: |
In: Journal of Acute Disease - Wolters Kluwer Medknow Publications, 2016, 8(2019), 3, Seite 113-117 |
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Übergeordnetes Werk: |
volume:8 ; year:2019 ; number:3 ; pages:113-117 |
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Link aufrufen |
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DOI / URN: |
10.4103/2221-6189.259110 |
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Katalog-ID: |
DOAJ052203859 |
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520 | |a Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. | ||
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10.4103/2221-6189.259110 doi (DE-627)DOAJ052203859 (DE-599)DOAJa568f168fe184f1eb084003ebdb7d0e4 DE-627 ger DE-627 rakwb eng RC86-88.9 Miaad K Alkhudhairy verfasserin aut Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. Escherichia coli Urinary tract infection Integrons IntI1 Medical emergencies. Critical care. Intensive care. First aid Morteza Saki verfasserin aut Sakineh Seyed–Mohammadi verfasserin aut Nabi Jomehzadeh verfasserin aut Saeed Khoshnood verfasserin aut Mina Moradzadeh verfasserin aut Sajjad Yazdansetad verfasserin aut In Journal of Acute Disease Wolters Kluwer Medknow Publications, 2016 8(2019), 3, Seite 113-117 (DE-627)775904619 (DE-600)2747536-0 25895516 nnns volume:8 year:2019 number:3 pages:113-117 https://doi.org/10.4103/2221-6189.259110 kostenfrei https://doaj.org/article/a568f168fe184f1eb084003ebdb7d0e4 kostenfrei http://www.jadweb.org/article.asp?issn=2221-6189;year=2019;volume=8;issue=3;spage=113;epage=117;aulast=Alkhudhairy kostenfrei https://doaj.org/toc/2221-6189 Journal toc kostenfrei https://doaj.org/toc/2589-5516 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 3 113-117 |
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10.4103/2221-6189.259110 doi (DE-627)DOAJ052203859 (DE-599)DOAJa568f168fe184f1eb084003ebdb7d0e4 DE-627 ger DE-627 rakwb eng RC86-88.9 Miaad K Alkhudhairy verfasserin aut Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. Escherichia coli Urinary tract infection Integrons IntI1 Medical emergencies. Critical care. Intensive care. First aid Morteza Saki verfasserin aut Sakineh Seyed–Mohammadi verfasserin aut Nabi Jomehzadeh verfasserin aut Saeed Khoshnood verfasserin aut Mina Moradzadeh verfasserin aut Sajjad Yazdansetad verfasserin aut In Journal of Acute Disease Wolters Kluwer Medknow Publications, 2016 8(2019), 3, Seite 113-117 (DE-627)775904619 (DE-600)2747536-0 25895516 nnns volume:8 year:2019 number:3 pages:113-117 https://doi.org/10.4103/2221-6189.259110 kostenfrei https://doaj.org/article/a568f168fe184f1eb084003ebdb7d0e4 kostenfrei http://www.jadweb.org/article.asp?issn=2221-6189;year=2019;volume=8;issue=3;spage=113;epage=117;aulast=Alkhudhairy kostenfrei https://doaj.org/toc/2221-6189 Journal toc kostenfrei https://doaj.org/toc/2589-5516 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 3 113-117 |
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10.4103/2221-6189.259110 doi (DE-627)DOAJ052203859 (DE-599)DOAJa568f168fe184f1eb084003ebdb7d0e4 DE-627 ger DE-627 rakwb eng RC86-88.9 Miaad K Alkhudhairy verfasserin aut Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. Escherichia coli Urinary tract infection Integrons IntI1 Medical emergencies. Critical care. Intensive care. First aid Morteza Saki verfasserin aut Sakineh Seyed–Mohammadi verfasserin aut Nabi Jomehzadeh verfasserin aut Saeed Khoshnood verfasserin aut Mina Moradzadeh verfasserin aut Sajjad Yazdansetad verfasserin aut In Journal of Acute Disease Wolters Kluwer Medknow Publications, 2016 8(2019), 3, Seite 113-117 (DE-627)775904619 (DE-600)2747536-0 25895516 nnns volume:8 year:2019 number:3 pages:113-117 https://doi.org/10.4103/2221-6189.259110 kostenfrei https://doaj.org/article/a568f168fe184f1eb084003ebdb7d0e4 kostenfrei http://www.jadweb.org/article.asp?issn=2221-6189;year=2019;volume=8;issue=3;spage=113;epage=117;aulast=Alkhudhairy kostenfrei https://doaj.org/toc/2221-6189 Journal toc kostenfrei https://doaj.org/toc/2589-5516 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 3 113-117 |
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10.4103/2221-6189.259110 doi (DE-627)DOAJ052203859 (DE-599)DOAJa568f168fe184f1eb084003ebdb7d0e4 DE-627 ger DE-627 rakwb eng RC86-88.9 Miaad K Alkhudhairy verfasserin aut Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. Escherichia coli Urinary tract infection Integrons IntI1 Medical emergencies. Critical care. Intensive care. First aid Morteza Saki verfasserin aut Sakineh Seyed–Mohammadi verfasserin aut Nabi Jomehzadeh verfasserin aut Saeed Khoshnood verfasserin aut Mina Moradzadeh verfasserin aut Sajjad Yazdansetad verfasserin aut In Journal of Acute Disease Wolters Kluwer Medknow Publications, 2016 8(2019), 3, Seite 113-117 (DE-627)775904619 (DE-600)2747536-0 25895516 nnns volume:8 year:2019 number:3 pages:113-117 https://doi.org/10.4103/2221-6189.259110 kostenfrei https://doaj.org/article/a568f168fe184f1eb084003ebdb7d0e4 kostenfrei http://www.jadweb.org/article.asp?issn=2221-6189;year=2019;volume=8;issue=3;spage=113;epage=117;aulast=Alkhudhairy kostenfrei https://doaj.org/toc/2221-6189 Journal toc kostenfrei https://doaj.org/toc/2589-5516 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 3 113-117 |
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10.4103/2221-6189.259110 doi (DE-627)DOAJ052203859 (DE-599)DOAJa568f168fe184f1eb084003ebdb7d0e4 DE-627 ger DE-627 rakwb eng RC86-88.9 Miaad K Alkhudhairy verfasserin aut Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. Escherichia coli Urinary tract infection Integrons IntI1 Medical emergencies. Critical care. Intensive care. First aid Morteza Saki verfasserin aut Sakineh Seyed–Mohammadi verfasserin aut Nabi Jomehzadeh verfasserin aut Saeed Khoshnood verfasserin aut Mina Moradzadeh verfasserin aut Sajjad Yazdansetad verfasserin aut In Journal of Acute Disease Wolters Kluwer Medknow Publications, 2016 8(2019), 3, Seite 113-117 (DE-627)775904619 (DE-600)2747536-0 25895516 nnns volume:8 year:2019 number:3 pages:113-117 https://doi.org/10.4103/2221-6189.259110 kostenfrei https://doaj.org/article/a568f168fe184f1eb084003ebdb7d0e4 kostenfrei http://www.jadweb.org/article.asp?issn=2221-6189;year=2019;volume=8;issue=3;spage=113;epage=117;aulast=Alkhudhairy kostenfrei https://doaj.org/toc/2221-6189 Journal toc kostenfrei https://doaj.org/toc/2589-5516 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 3 113-117 |
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Miaad K Alkhudhairy Morteza Saki Sakineh Seyed–Mohammadi Nabi Jomehzadeh Saeed Khoshnood Mina Moradzadeh Sajjad Yazdansetad |
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Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran |
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Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. |
abstractGer |
Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. |
abstract_unstemmed |
Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia coli strains were collected from patients with urinary tract infection in Ahvaz, Southwest of Iran. Antibiotic susceptibility testing was performed. The presence of intI1, intI2, and intI3 genes was determined by polymerase chain reaction. Results: Antibiotic susceptibility testing disclosed the highest resistance rate to ampicillin (91.7%) followed by trimethoprim/sulfamethoxazole (65.8%), and ceftazidime (56.7%). The imipenem susceptibility rate was 91.7%. IntIl and intI2 were identified in 74 (61.6%) and 8 (6.6%) of Escherichia coli strains, respectively, but intI3 was not found in any isolates. The presence of integrons was significantly associated with resistance to ampicillin, trimethoprim/ sulfamethoxazole, ceftazidime, and ciprofloxacin antibiotics (P<0.05). Conclusions: The high resistant Escherichia coli isolates harboring class 1 integrons (intI1) were detected in patients with urinary tract infection in our region. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains. |
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Integron frequency of Escherichia coli strains from patients with urinary tract infection in Southwest of Iran |
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https://doi.org/10.4103/2221-6189.259110 https://doaj.org/article/a568f168fe184f1eb084003ebdb7d0e4 http://www.jadweb.org/article.asp?issn=2221-6189;year=2019;volume=8;issue=3;spage=113;epage=117;aulast=Alkhudhairy https://doaj.org/toc/2221-6189 https://doaj.org/toc/2589-5516 |
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