Thermofluidic chip containing virtual thermal wells

The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific ad...
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Autor*in:	Andrew J. Ferguson [verfasserIn] Matthew J. Hayes [verfasserIn] Blair C. Kirkpatrick [verfasserIn] Yen-chun Lin [verfasserIn] Vijay Narayan [verfasserIn] Albert Prak [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device

Übergeordnetes Werk:	In: Engineering Biology - Wiley, 2020, (2019)
Übergeordnetes Werk:	year:2019

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1049/enb.2018.5010

Katalog-ID:	DOAJ052441512

Internformat


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650		4	\|a molecular biophysics
650		4	\|a thermofluidic chip
650		4	\|a virtual thermal wells
650		4	\|a microscale islands
650		4	\|a controlled temperature
650		4	\|a open fluidic environment
650		4	\|a authors
650		4	\|a thermally controlled dna synthesis
650		4	\|a site-specific temperature control
650		4	\|a site-specific addressability
650		4	\|a thermal well concept
650		4	\|a prototype thermal array device
653		0	\|a Biology (General)
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publishDate	2019
allfields	10.1049/enb.2018.5010 doi (DE-627)DOAJ052441512 (DE-599)DOAJc133d3bd47da4d4080cc3a40b8610c92 DE-627 ger DE-627 rakwb eng QH301-705.5 Andrew J. Ferguson verfasserin aut Thermofluidic chip containing virtual thermal wells 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device. microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device Biology (General) Matthew J. Hayes verfasserin aut Blair C. Kirkpatrick verfasserin aut Yen-chun Lin verfasserin aut Vijay Narayan verfasserin aut Albert Prak verfasserin aut Albert Prak verfasserin aut In Engineering Biology Wiley, 2020 (2019) (DE-627)897218361 (DE-600)2904872-2 23986182 nnns year:2019 https://doi.org/10.1049/enb.2018.5010 kostenfrei https://doaj.org/article/c133d3bd47da4d4080cc3a40b8610c92 kostenfrei https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5010 kostenfrei https://doaj.org/toc/2398-6182 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019
spelling	10.1049/enb.2018.5010 doi (DE-627)DOAJ052441512 (DE-599)DOAJc133d3bd47da4d4080cc3a40b8610c92 DE-627 ger DE-627 rakwb eng QH301-705.5 Andrew J. Ferguson verfasserin aut Thermofluidic chip containing virtual thermal wells 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device. microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device Biology (General) Matthew J. Hayes verfasserin aut Blair C. Kirkpatrick verfasserin aut Yen-chun Lin verfasserin aut Vijay Narayan verfasserin aut Albert Prak verfasserin aut Albert Prak verfasserin aut In Engineering Biology Wiley, 2020 (2019) (DE-627)897218361 (DE-600)2904872-2 23986182 nnns year:2019 https://doi.org/10.1049/enb.2018.5010 kostenfrei https://doaj.org/article/c133d3bd47da4d4080cc3a40b8610c92 kostenfrei https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5010 kostenfrei https://doaj.org/toc/2398-6182 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019
allfields_unstemmed	10.1049/enb.2018.5010 doi (DE-627)DOAJ052441512 (DE-599)DOAJc133d3bd47da4d4080cc3a40b8610c92 DE-627 ger DE-627 rakwb eng QH301-705.5 Andrew J. Ferguson verfasserin aut Thermofluidic chip containing virtual thermal wells 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device. microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device Biology (General) Matthew J. Hayes verfasserin aut Blair C. Kirkpatrick verfasserin aut Yen-chun Lin verfasserin aut Vijay Narayan verfasserin aut Albert Prak verfasserin aut Albert Prak verfasserin aut In Engineering Biology Wiley, 2020 (2019) (DE-627)897218361 (DE-600)2904872-2 23986182 nnns year:2019 https://doi.org/10.1049/enb.2018.5010 kostenfrei https://doaj.org/article/c133d3bd47da4d4080cc3a40b8610c92 kostenfrei https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5010 kostenfrei https://doaj.org/toc/2398-6182 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019
allfieldsGer	10.1049/enb.2018.5010 doi (DE-627)DOAJ052441512 (DE-599)DOAJc133d3bd47da4d4080cc3a40b8610c92 DE-627 ger DE-627 rakwb eng QH301-705.5 Andrew J. Ferguson verfasserin aut Thermofluidic chip containing virtual thermal wells 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device. microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device Biology (General) Matthew J. Hayes verfasserin aut Blair C. Kirkpatrick verfasserin aut Yen-chun Lin verfasserin aut Vijay Narayan verfasserin aut Albert Prak verfasserin aut Albert Prak verfasserin aut In Engineering Biology Wiley, 2020 (2019) (DE-627)897218361 (DE-600)2904872-2 23986182 nnns year:2019 https://doi.org/10.1049/enb.2018.5010 kostenfrei https://doaj.org/article/c133d3bd47da4d4080cc3a40b8610c92 kostenfrei https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5010 kostenfrei https://doaj.org/toc/2398-6182 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019
allfieldsSound	10.1049/enb.2018.5010 doi (DE-627)DOAJ052441512 (DE-599)DOAJc133d3bd47da4d4080cc3a40b8610c92 DE-627 ger DE-627 rakwb eng QH301-705.5 Andrew J. Ferguson verfasserin aut Thermofluidic chip containing virtual thermal wells 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device. microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device Biology (General) Matthew J. Hayes verfasserin aut Blair C. Kirkpatrick verfasserin aut Yen-chun Lin verfasserin aut Vijay Narayan verfasserin aut Albert Prak verfasserin aut Albert Prak verfasserin aut In Engineering Biology Wiley, 2020 (2019) (DE-627)897218361 (DE-600)2904872-2 23986182 nnns year:2019 https://doi.org/10.1049/enb.2018.5010 kostenfrei https://doaj.org/article/c133d3bd47da4d4080cc3a40b8610c92 kostenfrei https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5010 kostenfrei https://doaj.org/toc/2398-6182 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019
language	English
source	In Engineering Biology (2019) year:2019
sourceStr	In Engineering Biology (2019) year:2019
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device Biology (General)
isfreeaccess_bool	true
container_title	Engineering Biology
authorswithroles_txt_mv	Andrew J. Ferguson @@aut@@ Matthew J. Hayes @@aut@@ Blair C. Kirkpatrick @@aut@@ Yen-chun Lin @@aut@@ Vijay Narayan @@aut@@ Albert Prak @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
hierarchy_top_id	897218361
id	DOAJ052441512
language_de	englisch
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callnumber-first	Q - Science
author	Andrew J. Ferguson
spellingShingle	Andrew J. Ferguson misc QH301-705.5 misc microfluidics misc temperature control misc dna misc molecular biophysics misc thermofluidic chip misc virtual thermal wells misc microscale islands misc controlled temperature misc open fluidic environment misc authors misc thermally controlled dna synthesis misc site-specific temperature control misc site-specific addressability misc thermal well concept misc prototype thermal array device misc Biology (General) Thermofluidic chip containing virtual thermal wells
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topic_title	QH301-705.5 Thermofluidic chip containing virtual thermal wells microfluidics temperature control dna molecular biophysics thermofluidic chip virtual thermal wells microscale islands controlled temperature open fluidic environment authors thermally controlled dna synthesis site-specific temperature control site-specific addressability thermal well concept prototype thermal array device
topic	misc QH301-705.5 misc microfluidics misc temperature control misc dna misc molecular biophysics misc thermofluidic chip misc virtual thermal wells misc microscale islands misc controlled temperature misc open fluidic environment misc authors misc thermally controlled dna synthesis misc site-specific temperature control misc site-specific addressability misc thermal well concept misc prototype thermal array device misc Biology (General)
topic_unstemmed	misc QH301-705.5 misc microfluidics misc temperature control misc dna misc molecular biophysics misc thermofluidic chip misc virtual thermal wells misc microscale islands misc controlled temperature misc open fluidic environment misc authors misc thermally controlled dna synthesis misc site-specific temperature control misc site-specific addressability misc thermal well concept misc prototype thermal array device misc Biology (General)
topic_browse	misc QH301-705.5 misc microfluidics misc temperature control misc dna misc molecular biophysics misc thermofluidic chip misc virtual thermal wells misc microscale islands misc controlled temperature misc open fluidic environment misc authors misc thermally controlled dna synthesis misc site-specific temperature control misc site-specific addressability misc thermal well concept misc prototype thermal array device misc Biology (General)
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title	Thermofluidic chip containing virtual thermal wells
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title_sort	thermofluidic chip containing virtual thermal wells
callnumber	QH301-705.5
title_auth	Thermofluidic chip containing virtual thermal wells
abstract	The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device.
abstractGer	The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device.
abstract_unstemmed	The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site-specific temperature control enables site-specific addressability of chemical reactions, for example, related to the phosphoramidite cycle. Here, the authors discuss the principle of the chip, supporting the thermal well concept by means of simulations as well as by showing a prototype thermal array device.
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title_short	Thermofluidic chip containing virtual thermal wells
url	https://doi.org/10.1049/enb.2018.5010 https://doaj.org/article/c133d3bd47da4d4080cc3a40b8610c92 https://digital-library.theiet.org/content/journals/10.1049/enb.2018.5010 https://doaj.org/toc/2398-6182
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up_date	2024-07-04T01:04:37.819Z
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