Characterization of <i<Citrus</i<<i<nobilis</i< Peel Methanolic Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity
Currently, the potential utilization of fruits and vegetable waste as a source of micronutrients and antioxidants has increased. The present study, therefore, aimed to determine the antimicrobial and anti-inflammatory activities of <i<Citrus nobilis</i< peel extract. A modified solvent e...
Ausführliche Beschreibung
Autor*in: |
Anjali Malik [verfasserIn] Agnieszka Najda [verfasserIn] Aarti Bains [verfasserIn] Renata Nurzyńska-Wierdak [verfasserIn] Prince Chawla [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Übergeordnetes Werk: |
In: Molecules - MDPI AG, 2003, 26(2021), 14, p 4310 |
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Übergeordnetes Werk: |
volume:26 ; year:2021 ; number:14, p 4310 |
Links: |
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DOI / URN: |
10.3390/molecules26144310 |
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Katalog-ID: |
DOAJ052733319 |
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10.3390/molecules26144310 doi (DE-627)DOAJ052733319 (DE-599)DOAJf9f9787a143c47ebabccb943aa10b813 DE-627 ger DE-627 rakwb eng QD241-441 Anjali Malik verfasserin aut Characterization of <i<Citrus</i<<i<nobilis</i< Peel Methanolic Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Currently, the potential utilization of fruits and vegetable waste as a source of micronutrients and antioxidants has increased. The present study, therefore, aimed to determine the antimicrobial and anti-inflammatory activities of <i<Citrus nobilis</i< peel extract. A modified solvent evaporation technique was employed for peel extract preparation. For effective utilization of the natural product, quantitative analysis of phenolic compounds was carried out using liquid chromatography and mass spectroscopy technique. Phenolic and flavonoids were present in high amounts, while β-carotene and lycopene were present in vestigial amounts. The antimicrobial efficiency of peel extract was evaluated against four bacterial strains including <i<Staphylococcus aureus</i< (MTCC 3160), <i<Klebsiella pneumoniae</i< (MTCC 3384), <i<Pseudomonas aeruginosa</i< (MTCC 2295), and <i<Salmonella typhimurium</i< (MTCC 1254), and one fungal strain <i<Candida albicans</i< (MTCC 183), and zone of inhibition was comparable to the positive control streptomycin and amphotericin B, respectively. The extract of <i<Citrus nobilis</i< peels showed effective anti-inflammatory activity during human red blood cell membrane stabilization (HRBC) and albumin denaturation assay. The extracts also exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity ranging from 53.46 to 81.13%. Therefore, the obtained results suggest that <i<Citrus nobilis</i< peel could be used as an excellent source of polyphenols and transformed into value-added products. <i<Citrus nobilis</i< peel methanolic extract antibacterial activity antifungal activity anti-inflammatory activity DPPH Organic chemistry Agnieszka Najda verfasserin aut Aarti Bains verfasserin aut Renata Nurzyńska-Wierdak verfasserin aut Prince Chawla verfasserin aut In Molecules MDPI AG, 2003 26(2021), 14, p 4310 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:26 year:2021 number:14, p 4310 https://doi.org/10.3390/molecules26144310 kostenfrei https://doaj.org/article/f9f9787a143c47ebabccb943aa10b813 kostenfrei https://www.mdpi.com/1420-3049/26/14/4310 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2021 14, p 4310 |
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10.3390/molecules26144310 doi (DE-627)DOAJ052733319 (DE-599)DOAJf9f9787a143c47ebabccb943aa10b813 DE-627 ger DE-627 rakwb eng QD241-441 Anjali Malik verfasserin aut Characterization of <i<Citrus</i<<i<nobilis</i< Peel Methanolic Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Currently, the potential utilization of fruits and vegetable waste as a source of micronutrients and antioxidants has increased. The present study, therefore, aimed to determine the antimicrobial and anti-inflammatory activities of <i<Citrus nobilis</i< peel extract. A modified solvent evaporation technique was employed for peel extract preparation. For effective utilization of the natural product, quantitative analysis of phenolic compounds was carried out using liquid chromatography and mass spectroscopy technique. Phenolic and flavonoids were present in high amounts, while β-carotene and lycopene were present in vestigial amounts. The antimicrobial efficiency of peel extract was evaluated against four bacterial strains including <i<Staphylococcus aureus</i< (MTCC 3160), <i<Klebsiella pneumoniae</i< (MTCC 3384), <i<Pseudomonas aeruginosa</i< (MTCC 2295), and <i<Salmonella typhimurium</i< (MTCC 1254), and one fungal strain <i<Candida albicans</i< (MTCC 183), and zone of inhibition was comparable to the positive control streptomycin and amphotericin B, respectively. The extract of <i<Citrus nobilis</i< peels showed effective anti-inflammatory activity during human red blood cell membrane stabilization (HRBC) and albumin denaturation assay. The extracts also exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity ranging from 53.46 to 81.13%. Therefore, the obtained results suggest that <i<Citrus nobilis</i< peel could be used as an excellent source of polyphenols and transformed into value-added products. <i<Citrus nobilis</i< peel methanolic extract antibacterial activity antifungal activity anti-inflammatory activity DPPH Organic chemistry Agnieszka Najda verfasserin aut Aarti Bains verfasserin aut Renata Nurzyńska-Wierdak verfasserin aut Prince Chawla verfasserin aut In Molecules MDPI AG, 2003 26(2021), 14, p 4310 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:26 year:2021 number:14, p 4310 https://doi.org/10.3390/molecules26144310 kostenfrei https://doaj.org/article/f9f9787a143c47ebabccb943aa10b813 kostenfrei https://www.mdpi.com/1420-3049/26/14/4310 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2021 14, p 4310 |
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2021-01-01T00:00:00Z |
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QD241-441 Characterization of <i<Citrus</i<<i<nobilis</i< Peel Methanolic Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity <i<Citrus nobilis</i< peel methanolic extract antibacterial activity antifungal activity anti-inflammatory activity DPPH |
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characterization of <i<citrus</i<<i<nobilis</i< peel methanolic extract for antioxidant, antimicrobial, and anti-inflammatory activity |
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Characterization of <i<Citrus</i<<i<nobilis</i< Peel Methanolic Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity |
abstract |
Currently, the potential utilization of fruits and vegetable waste as a source of micronutrients and antioxidants has increased. The present study, therefore, aimed to determine the antimicrobial and anti-inflammatory activities of <i<Citrus nobilis</i< peel extract. A modified solvent evaporation technique was employed for peel extract preparation. For effective utilization of the natural product, quantitative analysis of phenolic compounds was carried out using liquid chromatography and mass spectroscopy technique. Phenolic and flavonoids were present in high amounts, while β-carotene and lycopene were present in vestigial amounts. The antimicrobial efficiency of peel extract was evaluated against four bacterial strains including <i<Staphylococcus aureus</i< (MTCC 3160), <i<Klebsiella pneumoniae</i< (MTCC 3384), <i<Pseudomonas aeruginosa</i< (MTCC 2295), and <i<Salmonella typhimurium</i< (MTCC 1254), and one fungal strain <i<Candida albicans</i< (MTCC 183), and zone of inhibition was comparable to the positive control streptomycin and amphotericin B, respectively. The extract of <i<Citrus nobilis</i< peels showed effective anti-inflammatory activity during human red blood cell membrane stabilization (HRBC) and albumin denaturation assay. The extracts also exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity ranging from 53.46 to 81.13%. Therefore, the obtained results suggest that <i<Citrus nobilis</i< peel could be used as an excellent source of polyphenols and transformed into value-added products. |
abstractGer |
Currently, the potential utilization of fruits and vegetable waste as a source of micronutrients and antioxidants has increased. The present study, therefore, aimed to determine the antimicrobial and anti-inflammatory activities of <i<Citrus nobilis</i< peel extract. A modified solvent evaporation technique was employed for peel extract preparation. For effective utilization of the natural product, quantitative analysis of phenolic compounds was carried out using liquid chromatography and mass spectroscopy technique. Phenolic and flavonoids were present in high amounts, while β-carotene and lycopene were present in vestigial amounts. The antimicrobial efficiency of peel extract was evaluated against four bacterial strains including <i<Staphylococcus aureus</i< (MTCC 3160), <i<Klebsiella pneumoniae</i< (MTCC 3384), <i<Pseudomonas aeruginosa</i< (MTCC 2295), and <i<Salmonella typhimurium</i< (MTCC 1254), and one fungal strain <i<Candida albicans</i< (MTCC 183), and zone of inhibition was comparable to the positive control streptomycin and amphotericin B, respectively. The extract of <i<Citrus nobilis</i< peels showed effective anti-inflammatory activity during human red blood cell membrane stabilization (HRBC) and albumin denaturation assay. The extracts also exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity ranging from 53.46 to 81.13%. Therefore, the obtained results suggest that <i<Citrus nobilis</i< peel could be used as an excellent source of polyphenols and transformed into value-added products. |
abstract_unstemmed |
Currently, the potential utilization of fruits and vegetable waste as a source of micronutrients and antioxidants has increased. The present study, therefore, aimed to determine the antimicrobial and anti-inflammatory activities of <i<Citrus nobilis</i< peel extract. A modified solvent evaporation technique was employed for peel extract preparation. For effective utilization of the natural product, quantitative analysis of phenolic compounds was carried out using liquid chromatography and mass spectroscopy technique. Phenolic and flavonoids were present in high amounts, while β-carotene and lycopene were present in vestigial amounts. The antimicrobial efficiency of peel extract was evaluated against four bacterial strains including <i<Staphylococcus aureus</i< (MTCC 3160), <i<Klebsiella pneumoniae</i< (MTCC 3384), <i<Pseudomonas aeruginosa</i< (MTCC 2295), and <i<Salmonella typhimurium</i< (MTCC 1254), and one fungal strain <i<Candida albicans</i< (MTCC 183), and zone of inhibition was comparable to the positive control streptomycin and amphotericin B, respectively. The extract of <i<Citrus nobilis</i< peels showed effective anti-inflammatory activity during human red blood cell membrane stabilization (HRBC) and albumin denaturation assay. The extracts also exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity ranging from 53.46 to 81.13%. Therefore, the obtained results suggest that <i<Citrus nobilis</i< peel could be used as an excellent source of polyphenols and transformed into value-added products. |
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Characterization of <i<Citrus</i<<i<nobilis</i< Peel Methanolic Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity |
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The present study, therefore, aimed to determine the antimicrobial and anti-inflammatory activities of <i<Citrus nobilis</i< peel extract. A modified solvent evaporation technique was employed for peel extract preparation. For effective utilization of the natural product, quantitative analysis of phenolic compounds was carried out using liquid chromatography and mass spectroscopy technique. Phenolic and flavonoids were present in high amounts, while β-carotene and lycopene were present in vestigial amounts. The antimicrobial efficiency of peel extract was evaluated against four bacterial strains including <i<Staphylococcus aureus</i< (MTCC 3160), <i<Klebsiella pneumoniae</i< (MTCC 3384), <i<Pseudomonas aeruginosa</i< (MTCC 2295), and <i<Salmonella typhimurium</i< (MTCC 1254), and one fungal strain <i<Candida albicans</i< (MTCC 183), and zone of inhibition was comparable to the positive control streptomycin and amphotericin B, respectively. The extract of <i<Citrus nobilis</i< peels showed effective anti-inflammatory activity during human red blood cell membrane stabilization (HRBC) and albumin denaturation assay. The extracts also exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity ranging from 53.46 to 81.13%. 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