Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana

Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary hea...
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Autor*in:	Kwame Opare-Asamoah [verfasserIn] George Asumeng Koffuor [verfasserIn] Alhassan Abdul-Mumin [verfasserIn] Baba Mohammed Sulemana [verfasserIn] Majeed Saeed [verfasserIn] Lawrence Quaye [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress

Übergeordnetes Werk:	In: Journal of Research in Pharmacy Practice - Wolters Kluwer Medknow Publications, 2019, 10(2021), 1, Seite 30-37
Übergeordnetes Werk:	volume:10 ; year:2021 ; number:1 ; pages:30-37

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.4103/jrpp.JRPP_20_118

Katalog-ID:	DOAJ053043596

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520			\|a Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU.
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allfields	10.4103/jrpp.JRPP_20_118 doi (DE-627)DOAJ053043596 (DE-599)DOAJfee53598107c484eb14dfc116e1b2354 DE-627 ger DE-627 rakwb eng RS1-441 Kwame Opare-Asamoah verfasserin aut Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU. gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress Pharmacy and materia medica George Asumeng Koffuor verfasserin aut Alhassan Abdul-Mumin verfasserin aut Baba Mohammed Sulemana verfasserin aut Majeed Saeed verfasserin aut Lawrence Quaye verfasserin aut In Journal of Research in Pharmacy Practice Wolters Kluwer Medknow Publications, 2019 10(2021), 1, Seite 30-37 (DE-627)769222064 (DE-600)2734861-1 2279042X nnns volume:10 year:2021 number:1 pages:30-37 https://doi.org/10.4103/jrpp.JRPP_20_118 kostenfrei https://doaj.org/article/fee53598107c484eb14dfc116e1b2354 kostenfrei http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=1;spage=30;epage=37;aulast=Opare-Asamoah kostenfrei https://doaj.org/toc/2319-9644 Journal toc kostenfrei https://doaj.org/toc/2279-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 1 30-37
spelling	10.4103/jrpp.JRPP_20_118 doi (DE-627)DOAJ053043596 (DE-599)DOAJfee53598107c484eb14dfc116e1b2354 DE-627 ger DE-627 rakwb eng RS1-441 Kwame Opare-Asamoah verfasserin aut Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU. gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress Pharmacy and materia medica George Asumeng Koffuor verfasserin aut Alhassan Abdul-Mumin verfasserin aut Baba Mohammed Sulemana verfasserin aut Majeed Saeed verfasserin aut Lawrence Quaye verfasserin aut In Journal of Research in Pharmacy Practice Wolters Kluwer Medknow Publications, 2019 10(2021), 1, Seite 30-37 (DE-627)769222064 (DE-600)2734861-1 2279042X nnns volume:10 year:2021 number:1 pages:30-37 https://doi.org/10.4103/jrpp.JRPP_20_118 kostenfrei https://doaj.org/article/fee53598107c484eb14dfc116e1b2354 kostenfrei http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=1;spage=30;epage=37;aulast=Opare-Asamoah kostenfrei https://doaj.org/toc/2319-9644 Journal toc kostenfrei https://doaj.org/toc/2279-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 1 30-37
allfields_unstemmed	10.4103/jrpp.JRPP_20_118 doi (DE-627)DOAJ053043596 (DE-599)DOAJfee53598107c484eb14dfc116e1b2354 DE-627 ger DE-627 rakwb eng RS1-441 Kwame Opare-Asamoah verfasserin aut Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU. gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress Pharmacy and materia medica George Asumeng Koffuor verfasserin aut Alhassan Abdul-Mumin verfasserin aut Baba Mohammed Sulemana verfasserin aut Majeed Saeed verfasserin aut Lawrence Quaye verfasserin aut In Journal of Research in Pharmacy Practice Wolters Kluwer Medknow Publications, 2019 10(2021), 1, Seite 30-37 (DE-627)769222064 (DE-600)2734861-1 2279042X nnns volume:10 year:2021 number:1 pages:30-37 https://doi.org/10.4103/jrpp.JRPP_20_118 kostenfrei https://doaj.org/article/fee53598107c484eb14dfc116e1b2354 kostenfrei http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=1;spage=30;epage=37;aulast=Opare-Asamoah kostenfrei https://doaj.org/toc/2319-9644 Journal toc kostenfrei https://doaj.org/toc/2279-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 1 30-37
allfieldsGer	10.4103/jrpp.JRPP_20_118 doi (DE-627)DOAJ053043596 (DE-599)DOAJfee53598107c484eb14dfc116e1b2354 DE-627 ger DE-627 rakwb eng RS1-441 Kwame Opare-Asamoah verfasserin aut Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU. gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress Pharmacy and materia medica George Asumeng Koffuor verfasserin aut Alhassan Abdul-Mumin verfasserin aut Baba Mohammed Sulemana verfasserin aut Majeed Saeed verfasserin aut Lawrence Quaye verfasserin aut In Journal of Research in Pharmacy Practice Wolters Kluwer Medknow Publications, 2019 10(2021), 1, Seite 30-37 (DE-627)769222064 (DE-600)2734861-1 2279042X nnns volume:10 year:2021 number:1 pages:30-37 https://doi.org/10.4103/jrpp.JRPP_20_118 kostenfrei https://doaj.org/article/fee53598107c484eb14dfc116e1b2354 kostenfrei http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=1;spage=30;epage=37;aulast=Opare-Asamoah kostenfrei https://doaj.org/toc/2319-9644 Journal toc kostenfrei https://doaj.org/toc/2279-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 1 30-37
allfieldsSound	10.4103/jrpp.JRPP_20_118 doi (DE-627)DOAJ053043596 (DE-599)DOAJfee53598107c484eb14dfc116e1b2354 DE-627 ger DE-627 rakwb eng RS1-441 Kwame Opare-Asamoah verfasserin aut Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU. gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress Pharmacy and materia medica George Asumeng Koffuor verfasserin aut Alhassan Abdul-Mumin verfasserin aut Baba Mohammed Sulemana verfasserin aut Majeed Saeed verfasserin aut Lawrence Quaye verfasserin aut In Journal of Research in Pharmacy Practice Wolters Kluwer Medknow Publications, 2019 10(2021), 1, Seite 30-37 (DE-627)769222064 (DE-600)2734861-1 2279042X nnns volume:10 year:2021 number:1 pages:30-37 https://doi.org/10.4103/jrpp.JRPP_20_118 kostenfrei https://doaj.org/article/fee53598107c484eb14dfc116e1b2354 kostenfrei http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=1;spage=30;epage=37;aulast=Opare-Asamoah kostenfrei https://doaj.org/toc/2319-9644 Journal toc kostenfrei https://doaj.org/toc/2279-042X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 1 30-37
language	English
source	In Journal of Research in Pharmacy Practice 10(2021), 1, Seite 30-37 volume:10 year:2021 number:1 pages:30-37
sourceStr	In Journal of Research in Pharmacy Practice 10(2021), 1, Seite 30-37 volume:10 year:2021 number:1 pages:30-37
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress Pharmacy and materia medica
isfreeaccess_bool	true
container_title	Journal of Research in Pharmacy Practice
authorswithroles_txt_mv	Kwame Opare-Asamoah @@aut@@ George Asumeng Koffuor @@aut@@ Alhassan Abdul-Mumin @@aut@@ Baba Mohammed Sulemana @@aut@@ Majeed Saeed @@aut@@ Lawrence Quaye @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	769222064
id	DOAJ053043596
language_de	englisch
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callnumber-first	R - Medicine
author	Kwame Opare-Asamoah
spellingShingle	Kwame Opare-Asamoah misc RS1-441 misc gentamicin misc neonatal intensive care unit misc neonates misc preterm delivery misc respiratory distress misc Pharmacy and materia medica Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana
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topic_title	RS1-441 Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana gentamicin neonatal intensive care unit neonates preterm delivery respiratory distress
topic	misc RS1-441 misc gentamicin misc neonatal intensive care unit misc neonates misc preterm delivery misc respiratory distress misc Pharmacy and materia medica
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title	Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana
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title_full	Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana
author_sort	Kwame Opare-Asamoah
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author_browse	Kwame Opare-Asamoah George Asumeng Koffuor Alhassan Abdul-Mumin Baba Mohammed Sulemana Majeed Saeed Lawrence Quaye
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title_sort	clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in ghana
callnumber	RS1-441
title_auth	Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana
abstract	Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU.
abstractGer	Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU.
abstract_unstemmed	Objective: Neonates are more susceptible to infections, as well as medication toxicities. This study, therefore, sought to describe the clinical characteristics, medication prescription pattern, and treatment outcomes for neonates admitted to the neonatal intensive care unit (NICU) of a tertiary health-care facility in Ghana. Methods: A retrospective cross-sectional study was conducted to ascertain clinical records, conditions for admission, spectrum of medications prescribed, and treatment outcomes from neonatal patient folders. Findings: Of 667 folders reviewed (51.4% males and 48.6% female), 61.8% were preterm (mean gestational age: 34.2 ± 3.6 weeks), 64.6% had low birth weight (LBW) (mean birth weight: 2.1 ± 0.9 kg), 90.6% were delivered through spontaneous vaginal delivery, and 57.4% delivered at the tertiary health-care facility. Of the 667 neonates, 70%, 27.1%, and 2.9% were queried with one, two, or three medical conditions, respectively. Respiratory distress, preterm, and pyrexia were common single queried conditions (88.5%). LBW, hypothermia, and single queried medical conditions were associated (P ≤ 0.0001) with preterm male neonates. The mean duration of stay of preterm neonates was 3.5 ± 3.2 days (term babies: 1–2 days [P = 0.0085]). Of 1,565 medications prescribed to the 667 neonates, 67.5% were antibacterial, with gentamicin (53.0%) being the most prescribed. 98.4% of neonates were prescribed at least one medication (i.e., 67.5% were prescribed antibacterial medications, 14.6% supplements, 11.0% bronchodilators, and 7.0% antiseizure); mean medication combination 2.6 ± 0.8 per neonate. Majority (75.4%) of the cases reviewed had treatment success. Conclusion : Respiratory distress and preterm deliveries are predominant presenting conditions, with antibacterial medication, mainly gentamicin and ampicillin, on prescription. Treatment success is significantly high at the NICU.
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title_short	Clinical characteristics, medication prescription pattern, and treatment outcomes at the neonatal intensive care unit of a tertiary health-care facility in Ghana
url	https://doi.org/10.4103/jrpp.JRPP_20_118 https://doaj.org/article/fee53598107c484eb14dfc116e1b2354 http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=1;spage=30;epage=37;aulast=Opare-Asamoah https://doaj.org/toc/2319-9644 https://doaj.org/toc/2279-042X
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author2	George Asumeng Koffuor Alhassan Abdul-Mumin Baba Mohammed Sulemana Majeed Saeed Lawrence Quaye
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up_date	2024-07-03T15:28:38.951Z
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