New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure
Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐...
Ausführliche Beschreibung
Autor*in: |
Mizuyoshi Nagai [verfasserIn] Tomonori Itoh [verfasserIn] Masaru Ishida [verfasserIn] Tetsuya Fusazaki [verfasserIn] Takashi Komatsu [verfasserIn] Motoyuki Nakamura [verfasserIn] Yoshihiro Morino [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2019 |
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Übergeordnetes Werk: |
In: Journal of Arrhythmia - Wiley, 2017, 35(2019), 2, Seite 182-189 |
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Übergeordnetes Werk: |
volume:35 ; year:2019 ; number:2 ; pages:182-189 |
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Link aufrufen |
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DOI / URN: |
10.1002/joa3.12154 |
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Katalog-ID: |
DOAJ053913353 |
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520 | |a Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. | ||
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700 | 0 | |a Yoshihiro Morino |e verfasserin |4 aut | |
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10.1002/joa3.12154 doi (DE-627)DOAJ053913353 (DE-599)DOAJ966122cca49949e0b78054a904677db5 DE-627 ger DE-627 rakwb eng RC666-701 Mizuyoshi Nagai verfasserin aut New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. acute coronary syndrome atrial fibrillation CHADS2 score mortality new‐onset atrial fibrillation Diseases of the circulatory (Cardiovascular) system Tomonori Itoh verfasserin aut Masaru Ishida verfasserin aut Tetsuya Fusazaki verfasserin aut Takashi Komatsu verfasserin aut Motoyuki Nakamura verfasserin aut Yoshihiro Morino verfasserin aut In Journal of Arrhythmia Wiley, 2017 35(2019), 2, Seite 182-189 (DE-627)733750141 (DE-600)2696593-8 18832148 nnns volume:35 year:2019 number:2 pages:182-189 https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/article/966122cca49949e0b78054a904677db5 kostenfrei https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/toc/1880-4276 Journal toc kostenfrei https://doaj.org/toc/1883-2148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2019 2 182-189 |
spelling |
10.1002/joa3.12154 doi (DE-627)DOAJ053913353 (DE-599)DOAJ966122cca49949e0b78054a904677db5 DE-627 ger DE-627 rakwb eng RC666-701 Mizuyoshi Nagai verfasserin aut New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. acute coronary syndrome atrial fibrillation CHADS2 score mortality new‐onset atrial fibrillation Diseases of the circulatory (Cardiovascular) system Tomonori Itoh verfasserin aut Masaru Ishida verfasserin aut Tetsuya Fusazaki verfasserin aut Takashi Komatsu verfasserin aut Motoyuki Nakamura verfasserin aut Yoshihiro Morino verfasserin aut In Journal of Arrhythmia Wiley, 2017 35(2019), 2, Seite 182-189 (DE-627)733750141 (DE-600)2696593-8 18832148 nnns volume:35 year:2019 number:2 pages:182-189 https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/article/966122cca49949e0b78054a904677db5 kostenfrei https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/toc/1880-4276 Journal toc kostenfrei https://doaj.org/toc/1883-2148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2019 2 182-189 |
allfields_unstemmed |
10.1002/joa3.12154 doi (DE-627)DOAJ053913353 (DE-599)DOAJ966122cca49949e0b78054a904677db5 DE-627 ger DE-627 rakwb eng RC666-701 Mizuyoshi Nagai verfasserin aut New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. acute coronary syndrome atrial fibrillation CHADS2 score mortality new‐onset atrial fibrillation Diseases of the circulatory (Cardiovascular) system Tomonori Itoh verfasserin aut Masaru Ishida verfasserin aut Tetsuya Fusazaki verfasserin aut Takashi Komatsu verfasserin aut Motoyuki Nakamura verfasserin aut Yoshihiro Morino verfasserin aut In Journal of Arrhythmia Wiley, 2017 35(2019), 2, Seite 182-189 (DE-627)733750141 (DE-600)2696593-8 18832148 nnns volume:35 year:2019 number:2 pages:182-189 https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/article/966122cca49949e0b78054a904677db5 kostenfrei https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/toc/1880-4276 Journal toc kostenfrei https://doaj.org/toc/1883-2148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2019 2 182-189 |
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10.1002/joa3.12154 doi (DE-627)DOAJ053913353 (DE-599)DOAJ966122cca49949e0b78054a904677db5 DE-627 ger DE-627 rakwb eng RC666-701 Mizuyoshi Nagai verfasserin aut New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. acute coronary syndrome atrial fibrillation CHADS2 score mortality new‐onset atrial fibrillation Diseases of the circulatory (Cardiovascular) system Tomonori Itoh verfasserin aut Masaru Ishida verfasserin aut Tetsuya Fusazaki verfasserin aut Takashi Komatsu verfasserin aut Motoyuki Nakamura verfasserin aut Yoshihiro Morino verfasserin aut In Journal of Arrhythmia Wiley, 2017 35(2019), 2, Seite 182-189 (DE-627)733750141 (DE-600)2696593-8 18832148 nnns volume:35 year:2019 number:2 pages:182-189 https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/article/966122cca49949e0b78054a904677db5 kostenfrei https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/toc/1880-4276 Journal toc kostenfrei https://doaj.org/toc/1883-2148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2019 2 182-189 |
allfieldsSound |
10.1002/joa3.12154 doi (DE-627)DOAJ053913353 (DE-599)DOAJ966122cca49949e0b78054a904677db5 DE-627 ger DE-627 rakwb eng RC666-701 Mizuyoshi Nagai verfasserin aut New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. acute coronary syndrome atrial fibrillation CHADS2 score mortality new‐onset atrial fibrillation Diseases of the circulatory (Cardiovascular) system Tomonori Itoh verfasserin aut Masaru Ishida verfasserin aut Tetsuya Fusazaki verfasserin aut Takashi Komatsu verfasserin aut Motoyuki Nakamura verfasserin aut Yoshihiro Morino verfasserin aut In Journal of Arrhythmia Wiley, 2017 35(2019), 2, Seite 182-189 (DE-627)733750141 (DE-600)2696593-8 18832148 nnns volume:35 year:2019 number:2 pages:182-189 https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/article/966122cca49949e0b78054a904677db5 kostenfrei https://doi.org/10.1002/joa3.12154 kostenfrei https://doaj.org/toc/1880-4276 Journal toc kostenfrei https://doaj.org/toc/1883-2148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2019 2 182-189 |
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Mizuyoshi Nagai misc RC666-701 misc acute coronary syndrome misc atrial fibrillation misc CHADS2 score misc mortality misc new‐onset atrial fibrillation misc Diseases of the circulatory (Cardiovascular) system New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure |
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RC666-701 New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure acute coronary syndrome atrial fibrillation CHADS2 score mortality new‐onset atrial fibrillation |
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New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure |
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New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure |
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Mizuyoshi Nagai Tomonori Itoh Masaru Ishida Tetsuya Fusazaki Takashi Komatsu Motoyuki Nakamura Yoshihiro Morino |
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new‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure |
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New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure |
abstract |
Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. |
abstractGer |
Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. |
abstract_unstemmed |
Abstract Background The purpose of this study was to evaluate the prognostic value of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS). Methods A total 648 of consecutive ACS patients were divided into non‐AF and all‐AF groups. The all‐AF group was further subdivided into new‐onset AF and pre‐existing AF groups. We compared prognosis among these groups using the Cox regression analysis. Results The mean follow‐up period was 1.4 ± 1.2 years. Overall patient numbers were 538 in non‐AF and 110 in all‐AF groups (67 in new‐onset AF and 43 in pre‐existing AF). Seventy‐eight all‐cause deaths and 42 cardiac deaths were observed. New‐onset AF had a worse prognosis than the other groups in the Kaplan‐Meier analysis (P = 0.025) after observation. Cox regression analysis indicated no significant difference for all‐cause death among the three groups. The hazard ratio of congestive heart failure requiring hospitalization was significantly higher in the all‐AF and new‐onset AF group than in the non‐AF group. Multivariate logistic regression analysis revealed that renal dysfunction, peripheral arterial disease, Killip classification ≥2, and left ventricular ejection fraction (LVEF) were independent predictors of all‐cause death. The new‐onset AF group had the highest prevalence of Killip classification ≥2 and the lowest LVEF. Conclusion In our study, AF was not an independent predictor of all‐cause death, but new‐onset AF may be associated with worse prognosis and future heart failure. |
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New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure |
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