Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis
Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Rep...
Ausführliche Beschreibung
Autor*in: |
Alberto Abrate [verfasserIn] Andrea Gregori [verfasserIn] Alchiede Simonato [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Übergeordnetes Werk: |
In: Asian Journal of Urology - Elsevier, 2016, 6(2019), 3, Seite 230-241 |
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Übergeordnetes Werk: |
volume:6 ; year:2019 ; number:3 ; pages:230-241 |
Links: |
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DOI / URN: |
10.1016/j.ajur.2019.01.001 |
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Katalog-ID: |
DOAJ054634024 |
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520 | |a Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty | ||
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10.1016/j.ajur.2019.01.001 doi (DE-627)DOAJ054634024 (DE-599)DOAJ168326b7b2a245ca82bf13c5e43c480c DE-627 ger DE-627 rakwb eng RC870-923 Alberto Abrate verfasserin aut Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty Diseases of the genitourinary system. Urology Andrea Gregori verfasserin aut Alchiede Simonato verfasserin aut In Asian Journal of Urology Elsevier, 2016 6(2019), 3, Seite 230-241 (DE-627)833508512 (DE-600)2831144-9 22143882 nnns volume:6 year:2019 number:3 pages:230-241 https://doi.org/10.1016/j.ajur.2019.01.001 kostenfrei https://doaj.org/article/168326b7b2a245ca82bf13c5e43c480c kostenfrei http://www.sciencedirect.com/science/article/pii/S2214388219300013 kostenfrei https://doaj.org/toc/2214-3882 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2019 3 230-241 |
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10.1016/j.ajur.2019.01.001 doi (DE-627)DOAJ054634024 (DE-599)DOAJ168326b7b2a245ca82bf13c5e43c480c DE-627 ger DE-627 rakwb eng RC870-923 Alberto Abrate verfasserin aut Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty Diseases of the genitourinary system. Urology Andrea Gregori verfasserin aut Alchiede Simonato verfasserin aut In Asian Journal of Urology Elsevier, 2016 6(2019), 3, Seite 230-241 (DE-627)833508512 (DE-600)2831144-9 22143882 nnns volume:6 year:2019 number:3 pages:230-241 https://doi.org/10.1016/j.ajur.2019.01.001 kostenfrei https://doaj.org/article/168326b7b2a245ca82bf13c5e43c480c kostenfrei http://www.sciencedirect.com/science/article/pii/S2214388219300013 kostenfrei https://doaj.org/toc/2214-3882 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2019 3 230-241 |
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10.1016/j.ajur.2019.01.001 doi (DE-627)DOAJ054634024 (DE-599)DOAJ168326b7b2a245ca82bf13c5e43c480c DE-627 ger DE-627 rakwb eng RC870-923 Alberto Abrate verfasserin aut Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty Diseases of the genitourinary system. Urology Andrea Gregori verfasserin aut Alchiede Simonato verfasserin aut In Asian Journal of Urology Elsevier, 2016 6(2019), 3, Seite 230-241 (DE-627)833508512 (DE-600)2831144-9 22143882 nnns volume:6 year:2019 number:3 pages:230-241 https://doi.org/10.1016/j.ajur.2019.01.001 kostenfrei https://doaj.org/article/168326b7b2a245ca82bf13c5e43c480c kostenfrei http://www.sciencedirect.com/science/article/pii/S2214388219300013 kostenfrei https://doaj.org/toc/2214-3882 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2019 3 230-241 |
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10.1016/j.ajur.2019.01.001 doi (DE-627)DOAJ054634024 (DE-599)DOAJ168326b7b2a245ca82bf13c5e43c480c DE-627 ger DE-627 rakwb eng RC870-923 Alberto Abrate verfasserin aut Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty Diseases of the genitourinary system. Urology Andrea Gregori verfasserin aut Alchiede Simonato verfasserin aut In Asian Journal of Urology Elsevier, 2016 6(2019), 3, Seite 230-241 (DE-627)833508512 (DE-600)2831144-9 22143882 nnns volume:6 year:2019 number:3 pages:230-241 https://doi.org/10.1016/j.ajur.2019.01.001 kostenfrei https://doaj.org/article/168326b7b2a245ca82bf13c5e43c480c kostenfrei http://www.sciencedirect.com/science/article/pii/S2214388219300013 kostenfrei https://doaj.org/toc/2214-3882 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2019 3 230-241 |
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10.1016/j.ajur.2019.01.001 doi (DE-627)DOAJ054634024 (DE-599)DOAJ168326b7b2a245ca82bf13c5e43c480c DE-627 ger DE-627 rakwb eng RC870-923 Alberto Abrate verfasserin aut Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty Diseases of the genitourinary system. Urology Andrea Gregori verfasserin aut Alchiede Simonato verfasserin aut In Asian Journal of Urology Elsevier, 2016 6(2019), 3, Seite 230-241 (DE-627)833508512 (DE-600)2831144-9 22143882 nnns volume:6 year:2019 number:3 pages:230-241 https://doi.org/10.1016/j.ajur.2019.01.001 kostenfrei https://doaj.org/article/168326b7b2a245ca82bf13c5e43c480c kostenfrei http://www.sciencedirect.com/science/article/pii/S2214388219300013 kostenfrei https://doaj.org/toc/2214-3882 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2019 3 230-241 |
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Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis |
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Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty |
abstractGer |
Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty |
abstract_unstemmed |
Objective: To evaluate the functional results and complications of the lingual mucosal graft (LMG) urethroplasty and to sum up the current state of the art of this surgical technique. Methods: A systematic search of PubMed and Scopus electronic databases was performed, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies involving male patients treated with LMG urethroplasty for urethral stricture were included. Complete protocol is available at http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017080121. A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft (BMG) was performed, calculating the odds ratio (OR) and 95% confidence interval (CI). Results: Twenty original articles were included in the qualitative analysis. Strictures of 1.5–16.5 cm have been treated with LMG urethroplasty, due to the improvement of harvesting technique and very low rate of long-term oral complications. Very good functional results have been reported by different authors for LMG urethroplasty, with lower rate of oral complications than BMG. The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty |
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The meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty, respectively. An OR of 1.65 (95% CI [0.95–2.87], I2 = 0%) and 0.18 (95% CI [0.03–1.26], I2 = 68%) were found for LMG vs. BMG urethroplasty, in terms of success and oral complication rate, respectively. Conclusion: LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good results. Oral complications are temporary and minimally disabling, basically less than those for BMG, and depend mainly on the graft extent. Keywords: Lingual mucosal graft, Meta-analysis, Systematic review, Urethral stricture, Urethroplasty</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Diseases of the genitourinary system. 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