Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures

Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Shikha Gupta [verfasserIn] Supriya Sampley [verfasserIn] Suneet Kathuria [verfasserIn] Sunil Katyal [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	Adjuvants bupivacaine fentanyl intrathecal low dose spinal sufentanil

Übergeordnetes Werk:	In: Journal of Anaesthesiology Clinical Pharmacology - Wolters Kluwer Medknow Publications, 2006, 29(2013), 4, Seite 509-515
Übergeordnetes Werk:	volume:29 ; year:2013 ; number:4 ; pages:509-515

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.4103/0970-9185.119158

Katalog-ID:	DOAJ054699355

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520			\|a Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl.
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allfields	10.4103/0970-9185.119158 doi (DE-627)DOAJ054699355 (DE-599)DOAJa447c88e3a1d4e86a65bd48e77d80d83 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Shikha Gupta verfasserin aut Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl. Adjuvants bupivacaine fentanyl intrathecal low dose spinal sufentanil Anesthesiology Pharmacy and materia medica Supriya Sampley verfasserin aut Suneet Kathuria verfasserin aut Sunil Katyal verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 29(2013), 4, Seite 509-515 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:29 year:2013 number:4 pages:509-515 https://doi.org/10.4103/0970-9185.119158 kostenfrei https://doaj.org/article/a447c88e3a1d4e86a65bd48e77d80d83 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=4;spage=509;epage=515;aulast=Gupta kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 29 2013 4 509-515
spelling	10.4103/0970-9185.119158 doi (DE-627)DOAJ054699355 (DE-599)DOAJa447c88e3a1d4e86a65bd48e77d80d83 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Shikha Gupta verfasserin aut Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl. Adjuvants bupivacaine fentanyl intrathecal low dose spinal sufentanil Anesthesiology Pharmacy and materia medica Supriya Sampley verfasserin aut Suneet Kathuria verfasserin aut Sunil Katyal verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 29(2013), 4, Seite 509-515 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:29 year:2013 number:4 pages:509-515 https://doi.org/10.4103/0970-9185.119158 kostenfrei https://doaj.org/article/a447c88e3a1d4e86a65bd48e77d80d83 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=4;spage=509;epage=515;aulast=Gupta kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 29 2013 4 509-515
allfields_unstemmed	10.4103/0970-9185.119158 doi (DE-627)DOAJ054699355 (DE-599)DOAJa447c88e3a1d4e86a65bd48e77d80d83 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Shikha Gupta verfasserin aut Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl. Adjuvants bupivacaine fentanyl intrathecal low dose spinal sufentanil Anesthesiology Pharmacy and materia medica Supriya Sampley verfasserin aut Suneet Kathuria verfasserin aut Sunil Katyal verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 29(2013), 4, Seite 509-515 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:29 year:2013 number:4 pages:509-515 https://doi.org/10.4103/0970-9185.119158 kostenfrei https://doaj.org/article/a447c88e3a1d4e86a65bd48e77d80d83 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=4;spage=509;epage=515;aulast=Gupta kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 29 2013 4 509-515
allfieldsGer	10.4103/0970-9185.119158 doi (DE-627)DOAJ054699355 (DE-599)DOAJa447c88e3a1d4e86a65bd48e77d80d83 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Shikha Gupta verfasserin aut Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl. Adjuvants bupivacaine fentanyl intrathecal low dose spinal sufentanil Anesthesiology Pharmacy and materia medica Supriya Sampley verfasserin aut Suneet Kathuria verfasserin aut Sunil Katyal verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 29(2013), 4, Seite 509-515 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:29 year:2013 number:4 pages:509-515 https://doi.org/10.4103/0970-9185.119158 kostenfrei https://doaj.org/article/a447c88e3a1d4e86a65bd48e77d80d83 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=4;spage=509;epage=515;aulast=Gupta kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 29 2013 4 509-515
allfieldsSound	10.4103/0970-9185.119158 doi (DE-627)DOAJ054699355 (DE-599)DOAJa447c88e3a1d4e86a65bd48e77d80d83 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Shikha Gupta verfasserin aut Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl. Adjuvants bupivacaine fentanyl intrathecal low dose spinal sufentanil Anesthesiology Pharmacy and materia medica Supriya Sampley verfasserin aut Suneet Kathuria verfasserin aut Sunil Katyal verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 29(2013), 4, Seite 509-515 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:29 year:2013 number:4 pages:509-515 https://doi.org/10.4103/0970-9185.119158 kostenfrei https://doaj.org/article/a447c88e3a1d4e86a65bd48e77d80d83 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=4;spage=509;epage=515;aulast=Gupta kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 29 2013 4 509-515
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author	Shikha Gupta
spellingShingle	Shikha Gupta misc RD78.3-87.3 misc RS1-441 misc Adjuvants misc bupivacaine misc fentanyl misc intrathecal misc low dose spinal misc sufentanil misc Anesthesiology misc Pharmacy and materia medica Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures
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topic_title	RD78.3-87.3 RS1-441 Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures Adjuvants bupivacaine fentanyl intrathecal low dose spinal sufentanil
topic	misc RD78.3-87.3 misc RS1-441 misc Adjuvants misc bupivacaine misc fentanyl misc intrathecal misc low dose spinal misc sufentanil misc Anesthesiology misc Pharmacy and materia medica
topic_unstemmed	misc RD78.3-87.3 misc RS1-441 misc Adjuvants misc bupivacaine misc fentanyl misc intrathecal misc low dose spinal misc sufentanil misc Anesthesiology misc Pharmacy and materia medica
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title	Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures
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title_sort	intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures
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title_auth	Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures
abstract	Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl.
abstractGer	Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl.
abstract_unstemmed	Context: Opioids are being increasingly used these days as adjuvants to local anesthetics in spinal anesthesia. Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. Conclusions: Spinal anesthesia for endoscopic urological procedures in elderly patients using low dose bupivacaine (5 mg) combined with 10 μg sufentanil is associated with a lower incidence of hemodynamic instability, better quality and prolonged duration as compared to that by adding 25 μg fentanyl.
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title_short	Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures
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author2	Supriya Sampley Suneet Kathuria Sunil Katyal
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ppnlink	518957225
callnumber-subject	RD - Surgery
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doi_str	10.4103/0970-9185.119158
callnumber-a	RD78.3-87.3
up_date	2024-07-04T00:14:54.376Z
_version_	1803605344914505728
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Aim: The aim of this study is to compare the effects of adding sufentanil or fentanyl to low dose bupivacaine in spinal anesthesia for endoscopic urological procedures. Settings and Design: Prospective, randomized, double-blind study. Materials and Methods: A total of 90 elective endoscopic urological surgery patients, 40-80 years old, received spinal anesthesia with 7.5 mg hyperbaric bupivacaine 0.5% (Group A) or by adding sufentanil 10 g (Group B) or fentanyl 25 g (Group C) to 5 mg hyperbaric bupivacaine 0.5%. These groups were compared in terms of the quality of spinal anesthesia as well as analgesia. Statistical analysis used: Analysis of variance and Chi-square test. Results: The onset of sensory and motor blockade was significantly rapid in Group A as compared with Groups B and C. The maximum upper level of sensory block was higher in Group A patients than Groups B and C patients. Quality of analgesia was significantly better and prolonged in sufentanil group as compared with other two groups. Motor block was more intense and prolonged in Group A as compared with Groups B and C patients. Request for post-operative analgesic was significantly delayed in Group B patients. 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Intrathecal sufentanil or fentanyl as adjuvants to low dose bupivacaine in endoscopic urological procedures

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