Subtrochanteric Femoral Fracture in a Patient with Osteopetrosis: Treated with Internal Fixation and Complicated by Intraoperative Femoral Neck Fracture
Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Repu...
Ausführliche Beschreibung
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| Autor*in: |
Hua X [verfasserIn] Liu Z [verfasserIn] Wang X [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020 |
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In: International Journal of General Medicine - Dove Medical Press, 2008, (2020), Seite 1551-1557 |
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year:2020 ; pages:1551-1557 |
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| 520 | |a Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw | ||
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(DE-627)DOAJ055114989 (DE-599)DOAJ73385d2981114b87bcc4cfd05172df08 DE-627 ger DE-627 rakwb eng R5-920 Hua X verfasserin aut Subtrochanteric Femoral Fracture in a Patient with Osteopetrosis: Treated with Internal Fixation and Complicated by Intraoperative Femoral Neck Fracture 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw osteopetrosis autosomal dominant osteopetrosis subtrochanteric fracture dynamic hip screw Medicine (General) Liu Z verfasserin aut Wang X verfasserin aut In International Journal of General Medicine Dove Medical Press, 2008 (2020), Seite 1551-1557 (DE-627)578539691 (DE-600)2452220-X 11787074 nnns year:2020 pages:1551-1557 https://doaj.org/article/73385d2981114b87bcc4cfd05172df08 kostenfrei https://www.dovepress.com/subtrochanteric-femoral-fracture-in-a-patient-with-osteopetrosis-treat-peer-reviewed-article-IJGM kostenfrei https://doaj.org/toc/1178-7074 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2020 1551-1557 |
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(DE-627)DOAJ055114989 (DE-599)DOAJ73385d2981114b87bcc4cfd05172df08 DE-627 ger DE-627 rakwb eng R5-920 Hua X verfasserin aut Subtrochanteric Femoral Fracture in a Patient with Osteopetrosis: Treated with Internal Fixation and Complicated by Intraoperative Femoral Neck Fracture 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw osteopetrosis autosomal dominant osteopetrosis subtrochanteric fracture dynamic hip screw Medicine (General) Liu Z verfasserin aut Wang X verfasserin aut In International Journal of General Medicine Dove Medical Press, 2008 (2020), Seite 1551-1557 (DE-627)578539691 (DE-600)2452220-X 11787074 nnns year:2020 pages:1551-1557 https://doaj.org/article/73385d2981114b87bcc4cfd05172df08 kostenfrei https://www.dovepress.com/subtrochanteric-femoral-fracture-in-a-patient-with-osteopetrosis-treat-peer-reviewed-article-IJGM kostenfrei https://doaj.org/toc/1178-7074 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2020 1551-1557 |
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(DE-627)DOAJ055114989 (DE-599)DOAJ73385d2981114b87bcc4cfd05172df08 DE-627 ger DE-627 rakwb eng R5-920 Hua X verfasserin aut Subtrochanteric Femoral Fracture in a Patient with Osteopetrosis: Treated with Internal Fixation and Complicated by Intraoperative Femoral Neck Fracture 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw osteopetrosis autosomal dominant osteopetrosis subtrochanteric fracture dynamic hip screw Medicine (General) Liu Z verfasserin aut Wang X verfasserin aut In International Journal of General Medicine Dove Medical Press, 2008 (2020), Seite 1551-1557 (DE-627)578539691 (DE-600)2452220-X 11787074 nnns year:2020 pages:1551-1557 https://doaj.org/article/73385d2981114b87bcc4cfd05172df08 kostenfrei https://www.dovepress.com/subtrochanteric-femoral-fracture-in-a-patient-with-osteopetrosis-treat-peer-reviewed-article-IJGM kostenfrei https://doaj.org/toc/1178-7074 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2020 1551-1557 |
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(DE-627)DOAJ055114989 (DE-599)DOAJ73385d2981114b87bcc4cfd05172df08 DE-627 ger DE-627 rakwb eng R5-920 Hua X verfasserin aut Subtrochanteric Femoral Fracture in a Patient with Osteopetrosis: Treated with Internal Fixation and Complicated by Intraoperative Femoral Neck Fracture 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw osteopetrosis autosomal dominant osteopetrosis subtrochanteric fracture dynamic hip screw Medicine (General) Liu Z verfasserin aut Wang X verfasserin aut In International Journal of General Medicine Dove Medical Press, 2008 (2020), Seite 1551-1557 (DE-627)578539691 (DE-600)2452220-X 11787074 nnns year:2020 pages:1551-1557 https://doaj.org/article/73385d2981114b87bcc4cfd05172df08 kostenfrei https://www.dovepress.com/subtrochanteric-femoral-fracture-in-a-patient-with-osteopetrosis-treat-peer-reviewed-article-IJGM kostenfrei https://doaj.org/toc/1178-7074 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2020 1551-1557 |
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(DE-627)DOAJ055114989 (DE-599)DOAJ73385d2981114b87bcc4cfd05172df08 DE-627 ger DE-627 rakwb eng R5-920 Hua X verfasserin aut Subtrochanteric Femoral Fracture in a Patient with Osteopetrosis: Treated with Internal Fixation and Complicated by Intraoperative Femoral Neck Fracture 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw osteopetrosis autosomal dominant osteopetrosis subtrochanteric fracture dynamic hip screw Medicine (General) Liu Z verfasserin aut Wang X verfasserin aut In International Journal of General Medicine Dove Medical Press, 2008 (2020), Seite 1551-1557 (DE-627)578539691 (DE-600)2452220-X 11787074 nnns year:2020 pages:1551-1557 https://doaj.org/article/73385d2981114b87bcc4cfd05172df08 kostenfrei https://www.dovepress.com/subtrochanteric-femoral-fracture-in-a-patient-with-osteopetrosis-treat-peer-reviewed-article-IJGM kostenfrei https://doaj.org/toc/1178-7074 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2020 1551-1557 |
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Subtrochanteric Femoral Fracture in a Patient with Osteopetrosis: Treated with Internal Fixation and Complicated by Intraoperative Femoral Neck Fracture |
| abstract |
Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw |
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Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw |
| abstract_unstemmed |
Xing Hua,1 Zhenyu Liu,2 Xinjia Wang3 1Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 2Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of China; 3Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, People’s Republic of ChinaCorrespondence: Xinjia Wang Email docxjwang163.comObjective: Osteopetrosis (OP) is a rare, heritable skeletal disorder that is caused by osteoclast dysfunction, leading to failure of bone resorption and increased bone density. The fragility of such dense bone may result in an increased incidence of fractures. Furthermore, surgery in patients with OP is associated with increased technical difficulty and a higher risk of complications.Case Report: We report a case of a 20-year-old woman with autosomal dominant OP who developed a subtrochanteric femoral fracture. The fracture was treated by open reduction and internal fixation using a dynamic hip screw. Although technical difficulties were experienced and an intraoperative femoral neck fracture occurred, the surgical outcome was satisfactory. Union of the fractures was visible on radiographs obtained 12 months postoperatively. At 2 years postoperatively, the patient was completely free of any complications resulting from her injury and treatment.Conclusion: Open reduction and internal fixation may be an effective option for fractures in patients with OP. Orthopedic surgeons should be aware that the increased density and stiffness of osteopetrotic bone increases the risks of intraoperative technical difficulties, iatrogenic fractures, and postoperative complications.Kgeywords: osteopetrosis, autosomal dominant osteopetrosis, subtrochanteric fracture, dynamic hip screw |
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