Position statement of the Spanish Association of Paediatrics-Spanish Society of Paediatric Infectious Diseases (AEP-SEIP) on the treatment of Multidrug-resistant bacterial infections
A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococ...
Ausführliche Beschreibung
Autor*in: |
David Aguilera-Alonso [verfasserIn] Luis Escosa-García [verfasserIn] Walter Alfredo Goycochea-Valdivia [verfasserIn] Pere Soler-Palacín [verfasserIn] Jesús Saavedra-Lozano [verfasserIn] Carlos Rodrigo [verfasserIn] Emilia Cercenado [verfasserIn] José Tomás Ramos [verfasserIn] Fernando Baquero-Artigao [verfasserIn] |
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E-Artikel |
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Sprache: |
Spanisch |
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2019 |
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Übergeordnetes Werk: |
In: Anales de Pediatría (English Edition) - Elsevier, 2021, 91(2019), 5, Seite 351.e1-351.e13 |
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Übergeordnetes Werk: |
volume:91 ; year:2019 ; number:5 ; pages:351.e1-351.e13 |
Links: |
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DOI / URN: |
10.1016/j.anpede.2019.08.004 |
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Katalog-ID: |
DOAJ055683096 |
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520 | |a A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. | ||
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10.1016/j.anpede.2019.08.004 doi (DE-627)DOAJ055683096 (DE-599)DOAJ2ab9d3f4137749999e496ed03a5ed2f1 DE-627 ger DE-627 rakwb spa RJ1-570 David Aguilera-Alonso verfasserin aut Position statement of the Spanish Association of Paediatrics-Spanish Society of Paediatric Infectious Diseases (AEP-SEIP) on the treatment of Multidrug-resistant bacterial infections 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. Bacterias multirresistentes β-lactamasas de espectro extendido β-lactamasas AmpC Carbapenemasas Staphylococcus aureus resistente a meticilina Pediatrics Luis Escosa-García verfasserin aut Walter Alfredo Goycochea-Valdivia verfasserin aut Pere Soler-Palacín verfasserin aut Jesús Saavedra-Lozano verfasserin aut Carlos Rodrigo verfasserin aut Emilia Cercenado verfasserin aut José Tomás Ramos verfasserin aut Fernando Baquero-Artigao verfasserin aut In Anales de Pediatría (English Edition) Elsevier, 2021 91(2019), 5, Seite 351.e1-351.e13 (DE-627)833145525 (DE-600)2830901-7 23412879 nnns volume:91 year:2019 number:5 pages:351.e1-351.e13 https://doi.org/10.1016/j.anpede.2019.08.004 kostenfrei https://doaj.org/article/2ab9d3f4137749999e496ed03a5ed2f1 kostenfrei http://www.sciencedirect.com/science/article/pii/S2341287919301723 kostenfrei https://doaj.org/toc/2341-2879 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 91 2019 5 351.e1-351.e13 |
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10.1016/j.anpede.2019.08.004 doi (DE-627)DOAJ055683096 (DE-599)DOAJ2ab9d3f4137749999e496ed03a5ed2f1 DE-627 ger DE-627 rakwb spa RJ1-570 David Aguilera-Alonso verfasserin aut Position statement of the Spanish Association of Paediatrics-Spanish Society of Paediatric Infectious Diseases (AEP-SEIP) on the treatment of Multidrug-resistant bacterial infections 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. Bacterias multirresistentes β-lactamasas de espectro extendido β-lactamasas AmpC Carbapenemasas Staphylococcus aureus resistente a meticilina Pediatrics Luis Escosa-García verfasserin aut Walter Alfredo Goycochea-Valdivia verfasserin aut Pere Soler-Palacín verfasserin aut Jesús Saavedra-Lozano verfasserin aut Carlos Rodrigo verfasserin aut Emilia Cercenado verfasserin aut José Tomás Ramos verfasserin aut Fernando Baquero-Artigao verfasserin aut In Anales de Pediatría (English Edition) Elsevier, 2021 91(2019), 5, Seite 351.e1-351.e13 (DE-627)833145525 (DE-600)2830901-7 23412879 nnns volume:91 year:2019 number:5 pages:351.e1-351.e13 https://doi.org/10.1016/j.anpede.2019.08.004 kostenfrei https://doaj.org/article/2ab9d3f4137749999e496ed03a5ed2f1 kostenfrei http://www.sciencedirect.com/science/article/pii/S2341287919301723 kostenfrei https://doaj.org/toc/2341-2879 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 91 2019 5 351.e1-351.e13 |
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10.1016/j.anpede.2019.08.004 doi (DE-627)DOAJ055683096 (DE-599)DOAJ2ab9d3f4137749999e496ed03a5ed2f1 DE-627 ger DE-627 rakwb spa RJ1-570 David Aguilera-Alonso verfasserin aut Position statement of the Spanish Association of Paediatrics-Spanish Society of Paediatric Infectious Diseases (AEP-SEIP) on the treatment of Multidrug-resistant bacterial infections 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. Bacterias multirresistentes β-lactamasas de espectro extendido β-lactamasas AmpC Carbapenemasas Staphylococcus aureus resistente a meticilina Pediatrics Luis Escosa-García verfasserin aut Walter Alfredo Goycochea-Valdivia verfasserin aut Pere Soler-Palacín verfasserin aut Jesús Saavedra-Lozano verfasserin aut Carlos Rodrigo verfasserin aut Emilia Cercenado verfasserin aut José Tomás Ramos verfasserin aut Fernando Baquero-Artigao verfasserin aut In Anales de Pediatría (English Edition) Elsevier, 2021 91(2019), 5, Seite 351.e1-351.e13 (DE-627)833145525 (DE-600)2830901-7 23412879 nnns volume:91 year:2019 number:5 pages:351.e1-351.e13 https://doi.org/10.1016/j.anpede.2019.08.004 kostenfrei https://doaj.org/article/2ab9d3f4137749999e496ed03a5ed2f1 kostenfrei http://www.sciencedirect.com/science/article/pii/S2341287919301723 kostenfrei https://doaj.org/toc/2341-2879 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 91 2019 5 351.e1-351.e13 |
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10.1016/j.anpede.2019.08.004 doi (DE-627)DOAJ055683096 (DE-599)DOAJ2ab9d3f4137749999e496ed03a5ed2f1 DE-627 ger DE-627 rakwb spa RJ1-570 David Aguilera-Alonso verfasserin aut Position statement of the Spanish Association of Paediatrics-Spanish Society of Paediatric Infectious Diseases (AEP-SEIP) on the treatment of Multidrug-resistant bacterial infections 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. Bacterias multirresistentes β-lactamasas de espectro extendido β-lactamasas AmpC Carbapenemasas Staphylococcus aureus resistente a meticilina Pediatrics Luis Escosa-García verfasserin aut Walter Alfredo Goycochea-Valdivia verfasserin aut Pere Soler-Palacín verfasserin aut Jesús Saavedra-Lozano verfasserin aut Carlos Rodrigo verfasserin aut Emilia Cercenado verfasserin aut José Tomás Ramos verfasserin aut Fernando Baquero-Artigao verfasserin aut In Anales de Pediatría (English Edition) Elsevier, 2021 91(2019), 5, Seite 351.e1-351.e13 (DE-627)833145525 (DE-600)2830901-7 23412879 nnns volume:91 year:2019 number:5 pages:351.e1-351.e13 https://doi.org/10.1016/j.anpede.2019.08.004 kostenfrei https://doaj.org/article/2ab9d3f4137749999e496ed03a5ed2f1 kostenfrei http://www.sciencedirect.com/science/article/pii/S2341287919301723 kostenfrei https://doaj.org/toc/2341-2879 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 91 2019 5 351.e1-351.e13 |
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David Aguilera-Alonso Luis Escosa-García Walter Alfredo Goycochea-Valdivia Pere Soler-Palacín Jesús Saavedra-Lozano Carlos Rodrigo Emilia Cercenado José Tomás Ramos Fernando Baquero-Artigao |
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position statement of the spanish association of paediatrics-spanish society of paediatric infectious diseases (aep-seip) on the treatment of multidrug-resistant bacterial infections |
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Position statement of the Spanish Association of Paediatrics-Spanish Society of Paediatric Infectious Diseases (AEP-SEIP) on the treatment of Multidrug-resistant bacterial infections |
abstract |
A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. |
abstractGer |
A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. |
abstract_unstemmed |
A progressive increase in the incidence of infections caused by multidrug-resistant microorganisms is being reported. Among these resistant microorganisms, the main threats are extended-spectrum β-lactamase-, AmpC-, and carbapenemase-producing Gram-negative bacilli, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. To address this important problem, it is essential to establish pediatric Antimicrobial Stewardship programs, perform active epidemiological surveillance and develop an adequate infection control policy. The therapeutic approach of these infections is often complex, frequently requiring antibiotics with less experience in children. In this position document made by the Spanish Association of Pediatrics and the Spanish Society of Pediatric Infectious Diseases, the epidemiology and treatment of these infections are reviewed according to the best available evidence. Resumen: En los últimos años se ha evidenciado un incremento en la incidencia de infecciones por bacterias multirresistentes. Las principales amenazas son los bacilos gramnegativos productores de β-lactamasas de espectro extendido (BLEE), AmpC o carbapenemasas, Staphylococcus aureus resistente a meticilina y Enterococcus faecium resistente a vancomicina. Para hacer frente a este problema, es fundamental establecer programas de optimización en el uso de antimicrobianos (PROA) específicos para pediatría, realizar una vigilancia epidemiológica activa y desarrollar una adecuada política de control de infecciones. Su abordaje terapéutico es a menudo complejo y multidisciplinar, precisando frecuentemente el uso de antibióticos con menor experiencia. En este documento de posicionamiento, elaborado por la Asociación Española de Pediatría y la Sociedad Española de Infectología Pediátrica, se revisa la epidemiologia y el tratamiento de estas infecciones siguiendo la mejor evidencia disponible. |
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Position statement of the Spanish Association of Paediatrics-Spanish Society of Paediatric Infectious Diseases (AEP-SEIP) on the treatment of Multidrug-resistant bacterial infections |
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https://doi.org/10.1016/j.anpede.2019.08.004 https://doaj.org/article/2ab9d3f4137749999e496ed03a5ed2f1 http://www.sciencedirect.com/science/article/pii/S2341287919301723 https://doaj.org/toc/2341-2879 |
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Luis Escosa-García Walter Alfredo Goycochea-Valdivia Pere Soler-Palacín Jesús Saavedra-Lozano Carlos Rodrigo Emilia Cercenado José Tomás Ramos Fernando Baquero-Artigao |
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