Challenges of drug-resistant malaria

Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combi...
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Autor*in:	Sinha Shweta [verfasserIn] Medhi Bikash [verfasserIn] Sehgal Rakesh [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Malaria Drug Resistance Nanotechnology RNAi Stem cell Peptides

Übergeordnetes Werk:	In: Parasite - EDP Sciences, 2015, 21, p 61(2014)
Übergeordnetes Werk:	volume:21, p 61 ; year:2014

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1051/parasite/2014059

Katalog-ID:	DOAJ05633639X

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allfields	10.1051/parasite/2014059 doi (DE-627)DOAJ05633639X (DE-599)DOAJe43c9352c1194c24ae8f943ddba4f5a2 DE-627 ger DE-627 rakwb eng RC109-216 Sinha Shweta verfasserin aut Challenges of drug-resistant malaria 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combination therapies and other malaria control strategies, the confirmation of artemisinin resistance on the Cambodia–Thailand border threatened all the previous success. This review addresses the global scenario of antimalarial resistance and factors associated with it, with the main emphasis on futuristic approaches like nanotechnology and stem cell therapy that may impede resistant malaria, along with novel medications which are preparing to enter the global antimalarial market. These novel studies are likely to escalate over the coming years and will hopefully help to reduce the burden of malaria. Malaria Drug Resistance Nanotechnology RNAi Stem cell Peptides Infectious and parasitic diseases Medhi Bikash verfasserin aut Sehgal Rakesh verfasserin aut In Parasite EDP Sciences, 2015 21, p 61(2014) (DE-627)527642398 (DE-600)2278575-9 17761042 nnns volume:21, p 61 year:2014 https://doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/article/e43c9352c1194c24ae8f943ddba4f5a2 kostenfrei http://dx.doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/toc/1776-1042 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21, p 61 2014
spelling	10.1051/parasite/2014059 doi (DE-627)DOAJ05633639X (DE-599)DOAJe43c9352c1194c24ae8f943ddba4f5a2 DE-627 ger DE-627 rakwb eng RC109-216 Sinha Shweta verfasserin aut Challenges of drug-resistant malaria 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combination therapies and other malaria control strategies, the confirmation of artemisinin resistance on the Cambodia–Thailand border threatened all the previous success. This review addresses the global scenario of antimalarial resistance and factors associated with it, with the main emphasis on futuristic approaches like nanotechnology and stem cell therapy that may impede resistant malaria, along with novel medications which are preparing to enter the global antimalarial market. These novel studies are likely to escalate over the coming years and will hopefully help to reduce the burden of malaria. Malaria Drug Resistance Nanotechnology RNAi Stem cell Peptides Infectious and parasitic diseases Medhi Bikash verfasserin aut Sehgal Rakesh verfasserin aut In Parasite EDP Sciences, 2015 21, p 61(2014) (DE-627)527642398 (DE-600)2278575-9 17761042 nnns volume:21, p 61 year:2014 https://doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/article/e43c9352c1194c24ae8f943ddba4f5a2 kostenfrei http://dx.doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/toc/1776-1042 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21, p 61 2014
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allfieldsGer	10.1051/parasite/2014059 doi (DE-627)DOAJ05633639X (DE-599)DOAJe43c9352c1194c24ae8f943ddba4f5a2 DE-627 ger DE-627 rakwb eng RC109-216 Sinha Shweta verfasserin aut Challenges of drug-resistant malaria 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combination therapies and other malaria control strategies, the confirmation of artemisinin resistance on the Cambodia–Thailand border threatened all the previous success. This review addresses the global scenario of antimalarial resistance and factors associated with it, with the main emphasis on futuristic approaches like nanotechnology and stem cell therapy that may impede resistant malaria, along with novel medications which are preparing to enter the global antimalarial market. These novel studies are likely to escalate over the coming years and will hopefully help to reduce the burden of malaria. Malaria Drug Resistance Nanotechnology RNAi Stem cell Peptides Infectious and parasitic diseases Medhi Bikash verfasserin aut Sehgal Rakesh verfasserin aut In Parasite EDP Sciences, 2015 21, p 61(2014) (DE-627)527642398 (DE-600)2278575-9 17761042 nnns volume:21, p 61 year:2014 https://doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/article/e43c9352c1194c24ae8f943ddba4f5a2 kostenfrei http://dx.doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/toc/1776-1042 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21, p 61 2014
allfieldsSound	10.1051/parasite/2014059 doi (DE-627)DOAJ05633639X (DE-599)DOAJe43c9352c1194c24ae8f943ddba4f5a2 DE-627 ger DE-627 rakwb eng RC109-216 Sinha Shweta verfasserin aut Challenges of drug-resistant malaria 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combination therapies and other malaria control strategies, the confirmation of artemisinin resistance on the Cambodia–Thailand border threatened all the previous success. This review addresses the global scenario of antimalarial resistance and factors associated with it, with the main emphasis on futuristic approaches like nanotechnology and stem cell therapy that may impede resistant malaria, along with novel medications which are preparing to enter the global antimalarial market. These novel studies are likely to escalate over the coming years and will hopefully help to reduce the burden of malaria. Malaria Drug Resistance Nanotechnology RNAi Stem cell Peptides Infectious and parasitic diseases Medhi Bikash verfasserin aut Sehgal Rakesh verfasserin aut In Parasite EDP Sciences, 2015 21, p 61(2014) (DE-627)527642398 (DE-600)2278575-9 17761042 nnns volume:21, p 61 year:2014 https://doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/article/e43c9352c1194c24ae8f943ddba4f5a2 kostenfrei http://dx.doi.org/10.1051/parasite/2014059 kostenfrei https://doaj.org/toc/1776-1042 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21, p 61 2014
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title_sort	challenges of drug-resistant malaria
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title_auth	Challenges of drug-resistant malaria
abstract	Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combination therapies and other malaria control strategies, the confirmation of artemisinin resistance on the Cambodia–Thailand border threatened all the previous success. This review addresses the global scenario of antimalarial resistance and factors associated with it, with the main emphasis on futuristic approaches like nanotechnology and stem cell therapy that may impede resistant malaria, along with novel medications which are preparing to enter the global antimalarial market. These novel studies are likely to escalate over the coming years and will hopefully help to reduce the burden of malaria.
abstractGer	Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combination therapies and other malaria control strategies, the confirmation of artemisinin resistance on the Cambodia–Thailand border threatened all the previous success. This review addresses the global scenario of antimalarial resistance and factors associated with it, with the main emphasis on futuristic approaches like nanotechnology and stem cell therapy that may impede resistant malaria, along with novel medications which are preparing to enter the global antimalarial market. These novel studies are likely to escalate over the coming years and will hopefully help to reduce the burden of malaria.
abstract_unstemmed	Over the past six decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern. Despite the remarkable progress that has been made in recent years in reducing the mortality rate to about 30% with the scaling-up of vector control, introduction of artemisinin-based combination therapies and other malaria control strategies, the confirmation of artemisinin resistance on the Cambodia–Thailand border threatened all the previous success. This review addresses the global scenario of antimalarial resistance and factors associated with it, with the main emphasis on futuristic approaches like nanotechnology and stem cell therapy that may impede resistant malaria, along with novel medications which are preparing to enter the global antimalarial market. These novel studies are likely to escalate over the coming years and will hopefully help to reduce the burden of malaria.
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