Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis

In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasoun...
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Autor*in:	Po-Ke Hsu [verfasserIn] Li-Sha Wu [verfasserIn] Hsu-Heng Yen [verfasserIn] Hsiu Ping Huang [verfasserIn] Yang-Yuan Chen [verfasserIn] Pei-Yuan Su [verfasserIn] Wei-Wen Su [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	attenuation imaging ultrasound liver steatosis

Übergeordnetes Werk:	In: Journal of Clinical Medicine - MDPI AG, 2013, 10(2021), 5, p 965
Übergeordnetes Werk:	volume:10 ; year:2021 ; number:5, p 965

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/jcm10050965

Katalog-ID:	DOAJ056636695

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allfields	10.3390/jcm10050965 doi (DE-627)DOAJ056636695 (DE-599)DOAJ7f715da3813549a096b480e39f45bab3 DE-627 ger DE-627 rakwb eng Po-Ke Hsu verfasserin aut Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice. attenuation imaging ultrasound liver steatosis Medicine R Li-Sha Wu verfasserin aut Hsu-Heng Yen verfasserin aut Hsiu Ping Huang verfasserin aut Yang-Yuan Chen verfasserin aut Pei-Yuan Su verfasserin aut Wei-Wen Su verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 5, p 965 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:5, p 965 https://doi.org/10.3390/jcm10050965 kostenfrei https://doaj.org/article/7f715da3813549a096b480e39f45bab3 kostenfrei https://www.mdpi.com/2077-0383/10/5/965 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 5, p 965
spelling	10.3390/jcm10050965 doi (DE-627)DOAJ056636695 (DE-599)DOAJ7f715da3813549a096b480e39f45bab3 DE-627 ger DE-627 rakwb eng Po-Ke Hsu verfasserin aut Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice. attenuation imaging ultrasound liver steatosis Medicine R Li-Sha Wu verfasserin aut Hsu-Heng Yen verfasserin aut Hsiu Ping Huang verfasserin aut Yang-Yuan Chen verfasserin aut Pei-Yuan Su verfasserin aut Wei-Wen Su verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 5, p 965 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:5, p 965 https://doi.org/10.3390/jcm10050965 kostenfrei https://doaj.org/article/7f715da3813549a096b480e39f45bab3 kostenfrei https://www.mdpi.com/2077-0383/10/5/965 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 5, p 965
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allfieldsGer	10.3390/jcm10050965 doi (DE-627)DOAJ056636695 (DE-599)DOAJ7f715da3813549a096b480e39f45bab3 DE-627 ger DE-627 rakwb eng Po-Ke Hsu verfasserin aut Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice. attenuation imaging ultrasound liver steatosis Medicine R Li-Sha Wu verfasserin aut Hsu-Heng Yen verfasserin aut Hsiu Ping Huang verfasserin aut Yang-Yuan Chen verfasserin aut Pei-Yuan Su verfasserin aut Wei-Wen Su verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 5, p 965 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:5, p 965 https://doi.org/10.3390/jcm10050965 kostenfrei https://doaj.org/article/7f715da3813549a096b480e39f45bab3 kostenfrei https://www.mdpi.com/2077-0383/10/5/965 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 5, p 965
allfieldsSound	10.3390/jcm10050965 doi (DE-627)DOAJ056636695 (DE-599)DOAJ7f715da3813549a096b480e39f45bab3 DE-627 ger DE-627 rakwb eng Po-Ke Hsu verfasserin aut Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice. attenuation imaging ultrasound liver steatosis Medicine R Li-Sha Wu verfasserin aut Hsu-Heng Yen verfasserin aut Hsiu Ping Huang verfasserin aut Yang-Yuan Chen verfasserin aut Pei-Yuan Su verfasserin aut Wei-Wen Su verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 5, p 965 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:5, p 965 https://doi.org/10.3390/jcm10050965 kostenfrei https://doaj.org/article/7f715da3813549a096b480e39f45bab3 kostenfrei https://www.mdpi.com/2077-0383/10/5/965 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 5, p 965
language	English
source	In Journal of Clinical Medicine 10(2021), 5, p 965 volume:10 year:2021 number:5, p 965
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author	Po-Ke Hsu
spellingShingle	Po-Ke Hsu misc attenuation imaging misc ultrasound misc liver steatosis misc Medicine misc R Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis
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topic_title	Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis attenuation imaging ultrasound liver steatosis
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title	Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis
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title_full	Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis
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title_sort	attenuation imaging with ultrasound as a novel evaluation method for liver steatosis
title_auth	Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis
abstract	In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice.
abstractGer	In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice.
abstract_unstemmed	In recent years, ultrasound attenuation imaging (ATI) has emerged as a new method to detect liver steatosis. However, thus far, no studies have confirmed the clinical utility of this technology. Using a retrospective database analysis of 28 patients with chronic liver disease who underwent ultrasound liver biopsy and ATI, we compared the presence and degree of steatosis measured by ATI with the results obtained through liver biopsy. The area under the receiver operating characteristic curve (AUROC) of the ATI for differentiating between normal and hepatic steatosis was 0.97 (95% confidence interval: 0.83–1.00). The AUROC of the ATI was 0.99 (95% confidence interval: 0.86–1.00) in grade ≥2 liver steatosis and 0.97 (95% confidence interval: 0.82–1.00) in grade 3. ATI showed good consistency and accuracy for the steatosis grading of liver biopsy. Therefore, ATI represents a novel diagnostic measurement to support the diagnosis of liver steatosis in non-invasive clinical practice.
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title_short	Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis
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