Sex differences in patients undergoing transcatheter aortic valve replacement in Asia

Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex di...
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Autor*in:	Mao Chen [verfasserIn] Wei-Hsian Yin [verfasserIn] Hsien-Li Kao [verfasserIn] Mao-Shin Lin [verfasserIn] Paul T L Chiam [verfasserIn] Michael K Y Lee [verfasserIn] Fabio Enrique Posas [verfasserIn] Mann Chandavimol [verfasserIn] Wacin Buddhari [verfasserIn] Timothy C Dy [verfasserIn] Ngoc Quang Nguyen [verfasserIn] Won Jang Kim [verfasserIn] Kiyuk Chang [verfasserIn] Yat-Yin Lam [verfasserIn] Hung Manh Pham [verfasserIn] Shaiful Azmi Yahaya [verfasserIn] Kay Woon Ho [verfasserIn] Wenzhi Pan [verfasserIn] Xian-bao Liu [verfasserIn] Jian'an Wang [verfasserIn] Hyo Soo Kim [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Übergeordnetes Werk:	In: Open Heart - BMJ Publishing Group, 2014, 8(2021), 1
Übergeordnetes Werk:	volume:8 ; year:2021 ; number:1

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1136/openhrt-2020-001541

Katalog-ID:	DOAJ058484655

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520			\|a Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival.
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allfields	10.1136/openhrt-2020-001541 doi (DE-627)DOAJ058484655 (DE-599)DOAJ1e30b983038f446eba1b5b67a8f4813a DE-627 ger DE-627 rakwb eng RC666-701 Mao Chen verfasserin aut Sex differences in patients undergoing transcatheter aortic valve replacement in Asia 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival. Diseases of the circulatory (Cardiovascular) system Wei-Hsian Yin verfasserin aut Hsien-Li Kao verfasserin aut Mao-Shin Lin verfasserin aut Paul T L Chiam verfasserin aut Michael K Y Lee verfasserin aut Fabio Enrique Posas verfasserin aut Mann Chandavimol verfasserin aut Wacin Buddhari verfasserin aut Timothy C Dy verfasserin aut Ngoc Quang Nguyen verfasserin aut Won Jang Kim verfasserin aut Kiyuk Chang verfasserin aut Yat-Yin Lam verfasserin aut Hung Manh Pham verfasserin aut Shaiful Azmi Yahaya verfasserin aut Kay Woon Ho verfasserin aut Wenzhi Pan verfasserin aut Xian-bao Liu verfasserin aut Jian'an Wang verfasserin aut Hyo Soo Kim verfasserin aut In Open Heart BMJ Publishing Group, 2014 8(2021), 1 (DE-627)775235482 (DE-600)2747269-3 20533624 nnns volume:8 year:2021 number:1 https://doi.org/10.1136/openhrt-2020-001541 kostenfrei https://doaj.org/article/1e30b983038f446eba1b5b67a8f4813a kostenfrei https://openheart.bmj.com/content/8/1/e001541.full kostenfrei https://doaj.org/toc/2053-3624 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 1
spelling	10.1136/openhrt-2020-001541 doi (DE-627)DOAJ058484655 (DE-599)DOAJ1e30b983038f446eba1b5b67a8f4813a DE-627 ger DE-627 rakwb eng RC666-701 Mao Chen verfasserin aut Sex differences in patients undergoing transcatheter aortic valve replacement in Asia 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival. Diseases of the circulatory (Cardiovascular) system Wei-Hsian Yin verfasserin aut Hsien-Li Kao verfasserin aut Mao-Shin Lin verfasserin aut Paul T L Chiam verfasserin aut Michael K Y Lee verfasserin aut Fabio Enrique Posas verfasserin aut Mann Chandavimol verfasserin aut Wacin Buddhari verfasserin aut Timothy C Dy verfasserin aut Ngoc Quang Nguyen verfasserin aut Won Jang Kim verfasserin aut Kiyuk Chang verfasserin aut Yat-Yin Lam verfasserin aut Hung Manh Pham verfasserin aut Shaiful Azmi Yahaya verfasserin aut Kay Woon Ho verfasserin aut Wenzhi Pan verfasserin aut Xian-bao Liu verfasserin aut Jian'an Wang verfasserin aut Hyo Soo Kim verfasserin aut In Open Heart BMJ Publishing Group, 2014 8(2021), 1 (DE-627)775235482 (DE-600)2747269-3 20533624 nnns volume:8 year:2021 number:1 https://doi.org/10.1136/openhrt-2020-001541 kostenfrei https://doaj.org/article/1e30b983038f446eba1b5b67a8f4813a kostenfrei https://openheart.bmj.com/content/8/1/e001541.full kostenfrei https://doaj.org/toc/2053-3624 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 1
allfields_unstemmed	10.1136/openhrt-2020-001541 doi (DE-627)DOAJ058484655 (DE-599)DOAJ1e30b983038f446eba1b5b67a8f4813a DE-627 ger DE-627 rakwb eng RC666-701 Mao Chen verfasserin aut Sex differences in patients undergoing transcatheter aortic valve replacement in Asia 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival. Diseases of the circulatory (Cardiovascular) system Wei-Hsian Yin verfasserin aut Hsien-Li Kao verfasserin aut Mao-Shin Lin verfasserin aut Paul T L Chiam verfasserin aut Michael K Y Lee verfasserin aut Fabio Enrique Posas verfasserin aut Mann Chandavimol verfasserin aut Wacin Buddhari verfasserin aut Timothy C Dy verfasserin aut Ngoc Quang Nguyen verfasserin aut Won Jang Kim verfasserin aut Kiyuk Chang verfasserin aut Yat-Yin Lam verfasserin aut Hung Manh Pham verfasserin aut Shaiful Azmi Yahaya verfasserin aut Kay Woon Ho verfasserin aut Wenzhi Pan verfasserin aut Xian-bao Liu verfasserin aut Jian'an Wang verfasserin aut Hyo Soo Kim verfasserin aut In Open Heart BMJ Publishing Group, 2014 8(2021), 1 (DE-627)775235482 (DE-600)2747269-3 20533624 nnns volume:8 year:2021 number:1 https://doi.org/10.1136/openhrt-2020-001541 kostenfrei https://doaj.org/article/1e30b983038f446eba1b5b67a8f4813a kostenfrei https://openheart.bmj.com/content/8/1/e001541.full kostenfrei https://doaj.org/toc/2053-3624 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 1
allfieldsGer	10.1136/openhrt-2020-001541 doi (DE-627)DOAJ058484655 (DE-599)DOAJ1e30b983038f446eba1b5b67a8f4813a DE-627 ger DE-627 rakwb eng RC666-701 Mao Chen verfasserin aut Sex differences in patients undergoing transcatheter aortic valve replacement in Asia 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival. Diseases of the circulatory (Cardiovascular) system Wei-Hsian Yin verfasserin aut Hsien-Li Kao verfasserin aut Mao-Shin Lin verfasserin aut Paul T L Chiam verfasserin aut Michael K Y Lee verfasserin aut Fabio Enrique Posas verfasserin aut Mann Chandavimol verfasserin aut Wacin Buddhari verfasserin aut Timothy C Dy verfasserin aut Ngoc Quang Nguyen verfasserin aut Won Jang Kim verfasserin aut Kiyuk Chang verfasserin aut Yat-Yin Lam verfasserin aut Hung Manh Pham verfasserin aut Shaiful Azmi Yahaya verfasserin aut Kay Woon Ho verfasserin aut Wenzhi Pan verfasserin aut Xian-bao Liu verfasserin aut Jian'an Wang verfasserin aut Hyo Soo Kim verfasserin aut In Open Heart BMJ Publishing Group, 2014 8(2021), 1 (DE-627)775235482 (DE-600)2747269-3 20533624 nnns volume:8 year:2021 number:1 https://doi.org/10.1136/openhrt-2020-001541 kostenfrei https://doaj.org/article/1e30b983038f446eba1b5b67a8f4813a kostenfrei https://openheart.bmj.com/content/8/1/e001541.full kostenfrei https://doaj.org/toc/2053-3624 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 1
allfieldsSound	10.1136/openhrt-2020-001541 doi (DE-627)DOAJ058484655 (DE-599)DOAJ1e30b983038f446eba1b5b67a8f4813a DE-627 ger DE-627 rakwb eng RC666-701 Mao Chen verfasserin aut Sex differences in patients undergoing transcatheter aortic valve replacement in Asia 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival. Diseases of the circulatory (Cardiovascular) system Wei-Hsian Yin verfasserin aut Hsien-Li Kao verfasserin aut Mao-Shin Lin verfasserin aut Paul T L Chiam verfasserin aut Michael K Y Lee verfasserin aut Fabio Enrique Posas verfasserin aut Mann Chandavimol verfasserin aut Wacin Buddhari verfasserin aut Timothy C Dy verfasserin aut Ngoc Quang Nguyen verfasserin aut Won Jang Kim verfasserin aut Kiyuk Chang verfasserin aut Yat-Yin Lam verfasserin aut Hung Manh Pham verfasserin aut Shaiful Azmi Yahaya verfasserin aut Kay Woon Ho verfasserin aut Wenzhi Pan verfasserin aut Xian-bao Liu verfasserin aut Jian'an Wang verfasserin aut Hyo Soo Kim verfasserin aut In Open Heart BMJ Publishing Group, 2014 8(2021), 1 (DE-627)775235482 (DE-600)2747269-3 20533624 nnns volume:8 year:2021 number:1 https://doi.org/10.1136/openhrt-2020-001541 kostenfrei https://doaj.org/article/1e30b983038f446eba1b5b67a8f4813a kostenfrei https://openheart.bmj.com/content/8/1/e001541.full kostenfrei https://doaj.org/toc/2053-3624 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 1
language	English
source	In Open Heart 8(2021), 1 volume:8 year:2021 number:1
sourceStr	In Open Heart 8(2021), 1 volume:8 year:2021 number:1
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Diseases of the circulatory (Cardiovascular) system
isfreeaccess_bool	true
container_title	Open Heart
authorswithroles_txt_mv	Mao Chen @@aut@@ Wei-Hsian Yin @@aut@@ Hsien-Li Kao @@aut@@ Mao-Shin Lin @@aut@@ Paul T L Chiam @@aut@@ Michael K Y Lee @@aut@@ Fabio Enrique Posas @@aut@@ Mann Chandavimol @@aut@@ Wacin Buddhari @@aut@@ Timothy C Dy @@aut@@ Ngoc Quang Nguyen @@aut@@ Won Jang Kim @@aut@@ Kiyuk Chang @@aut@@ Yat-Yin Lam @@aut@@ Hung Manh Pham @@aut@@ Shaiful Azmi Yahaya @@aut@@ Kay Woon Ho @@aut@@ Wenzhi Pan @@aut@@ Xian-bao Liu @@aut@@ Jian'an Wang @@aut@@ Hyo Soo Kim @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	775235482
id	DOAJ058484655
language_de	englisch
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Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p&lt;0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. 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callnumber-first	R - Medicine
author	Mao Chen
spellingShingle	Mao Chen misc RC666-701 misc Diseases of the circulatory (Cardiovascular) system Sex differences in patients undergoing transcatheter aortic valve replacement in Asia
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topic_title	RC666-701 Sex differences in patients undergoing transcatheter aortic valve replacement in Asia
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title	Sex differences in patients undergoing transcatheter aortic valve replacement in Asia
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title_full	Sex differences in patients undergoing transcatheter aortic valve replacement in Asia
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journal	Open Heart
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author_browse	Mao Chen Wei-Hsian Yin Hsien-Li Kao Mao-Shin Lin Paul T L Chiam Michael K Y Lee Fabio Enrique Posas Mann Chandavimol Wacin Buddhari Timothy C Dy Ngoc Quang Nguyen Won Jang Kim Kiyuk Chang Yat-Yin Lam Hung Manh Pham Shaiful Azmi Yahaya Kay Woon Ho Wenzhi Pan Xian-bao Liu Jian'an Wang Hyo Soo Kim
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doi_str_mv	10.1136/openhrt-2020-001541
author2-role	verfasserin
title_sort	sex differences in patients undergoing transcatheter aortic valve replacement in asia
callnumber	RC666-701
title_auth	Sex differences in patients undergoing transcatheter aortic valve replacement in Asia
abstract	Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival.
abstractGer	Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival.
abstract_unstemmed	Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p<0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements (11.2% vs 9.0%, p=0.52) were also similar as was 1-year survival (women vs men: 85.6% vs 88.2%, p=0.25). The only predictors of 30-day mortality were major vascular injury in women and age in men.Conclusions Asian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival.
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title_short	Sex differences in patients undergoing transcatheter aortic valve replacement in Asia
url	https://doi.org/10.1136/openhrt-2020-001541 https://doaj.org/article/1e30b983038f446eba1b5b67a8f4813a https://openheart.bmj.com/content/8/1/e001541.full https://doaj.org/toc/2053-3624
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author2	Wei-Hsian Yin Hsien-Li Kao Mao-Shin Lin Paul T L Chiam Michael K Y Lee Fabio Enrique Posas Mann Chandavimol Wacin Buddhari Timothy C Dy Ngoc Quang Nguyen Won Jang Kim Kiyuk Chang Yat-Yin Lam Hung Manh Pham Shaiful Azmi Yahaya Kay Woon Ho Wenzhi Pan Xian-bao Liu Jian'an Wang Hyo Soo Kim
author2Str	Wei-Hsian Yin Hsien-Li Kao Mao-Shin Lin Paul T L Chiam Michael K Y Lee Fabio Enrique Posas Mann Chandavimol Wacin Buddhari Timothy C Dy Ngoc Quang Nguyen Won Jang Kim Kiyuk Chang Yat-Yin Lam Hung Manh Pham Shaiful Azmi Yahaya Kay Woon Ho Wenzhi Pan Xian-bao Liu Jian'an Wang Hyo Soo Kim
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up_date	2024-07-03T18:16:29.895Z
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Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p&lt;0.01); however, 30-day stroke and mortality (women vs men: 1.5% vs 1.6%, p=0.95% and 4.3% vs 3.4%, p=0.48) were similar. 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Sex differences in patients undergoing transcatheter aortic valve replacement in Asia

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