Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis
Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough cul...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Moyurakhi Gogoi [verfasserIn] Manuj K Das [verfasserIn] Jayanta Kumar Das [verfasserIn] Nabanita Barman [verfasserIn] Pankaj Das [verfasserIn] Utpala Devi [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2021 |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
In: Journal of Clinical and Diagnostic Research - JCDR Research and Publications Private Limited, 2009, 15(2021), 4, Seite DC13-DC18 |
|---|---|
| Übergeordnetes Werk: |
volume:15 ; year:2021 ; number:4 ; pages:DC13-DC18 |
| Links: |
Link aufrufen |
|---|
| DOI / URN: |
10.7860/JCDR/2021/47750.14824 |
|---|
| Katalog-ID: |
DOAJ058594663 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ058594663 | ||
| 003 | DE-627 | ||
| 005 | 20230308225333.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230228s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.7860/JCDR/2021/47750.14824 |2 doi | |
| 035 | |a (DE-627)DOAJ058594663 | ||
| 035 | |a (DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 0 | |a Moyurakhi Gogoi |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. | ||
| 650 | 4 | |a antibiotic susceptibility test | |
| 650 | 4 | |a phylogenesis | |
| 650 | 4 | |a streptococcus agalactiae | |
| 650 | 4 | |a urinary tract infections | |
| 653 | 0 | |a Medicine | |
| 653 | 0 | |a R | |
| 700 | 0 | |a Manuj K Das |e verfasserin |4 aut | |
| 700 | 0 | |a Jayanta Kumar Das |e verfasserin |4 aut | |
| 700 | 0 | |a Nabanita Barman |e verfasserin |4 aut | |
| 700 | 0 | |a Pankaj Das |e verfasserin |4 aut | |
| 700 | 0 | |a Utpala Devi |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Journal of Clinical and Diagnostic Research |d JCDR Research and Publications Private Limited, 2009 |g 15(2021), 4, Seite DC13-DC18 |w (DE-627)789478048 |w (DE-600)2775283-5 |x 0973709X |7 nnns |
| 773 | 1 | 8 | |g volume:15 |g year:2021 |g number:4 |g pages:DC13-DC18 |
| 856 | 4 | 0 | |u https://doi.org/10.7860/JCDR/2021/47750.14824 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9 |z kostenfrei |
| 856 | 4 | 0 | |u https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2249-782X |y Journal toc |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/0973-709X |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 912 | |a GBV_ILN_20 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_23 | ||
| 912 | |a GBV_ILN_24 | ||
| 912 | |a GBV_ILN_39 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_60 | ||
| 912 | |a GBV_ILN_62 | ||
| 912 | |a GBV_ILN_63 | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a GBV_ILN_69 | ||
| 912 | |a GBV_ILN_73 | ||
| 912 | |a GBV_ILN_74 | ||
| 912 | |a GBV_ILN_95 | ||
| 912 | |a GBV_ILN_105 | ||
| 912 | |a GBV_ILN_110 | ||
| 912 | |a GBV_ILN_151 | ||
| 912 | |a GBV_ILN_161 | ||
| 912 | |a GBV_ILN_170 | ||
| 912 | |a GBV_ILN_206 | ||
| 912 | |a GBV_ILN_213 | ||
| 912 | |a GBV_ILN_230 | ||
| 912 | |a GBV_ILN_285 | ||
| 912 | |a GBV_ILN_293 | ||
| 912 | |a GBV_ILN_602 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2009 | ||
| 912 | |a GBV_ILN_2011 | ||
| 912 | |a GBV_ILN_2014 | ||
| 912 | |a GBV_ILN_2055 | ||
| 912 | |a GBV_ILN_2111 | ||
| 912 | |a GBV_ILN_4012 | ||
| 912 | |a GBV_ILN_4037 | ||
| 912 | |a GBV_ILN_4112 | ||
| 912 | |a GBV_ILN_4125 | ||
| 912 | |a GBV_ILN_4126 | ||
| 912 | |a GBV_ILN_4249 | ||
| 912 | |a GBV_ILN_4305 | ||
| 912 | |a GBV_ILN_4306 | ||
| 912 | |a GBV_ILN_4307 | ||
| 912 | |a GBV_ILN_4313 | ||
| 912 | |a GBV_ILN_4322 | ||
| 912 | |a GBV_ILN_4323 | ||
| 912 | |a GBV_ILN_4324 | ||
| 912 | |a GBV_ILN_4325 | ||
| 912 | |a GBV_ILN_4338 | ||
| 912 | |a GBV_ILN_4367 | ||
| 912 | |a GBV_ILN_4700 | ||
| 951 | |a AR | ||
| 952 | |d 15 |j 2021 |e 4 |h DC13-DC18 | ||
| author_variant |
m g mg m k d mkd j k d jkd n b nb p d pd u d ud |
|---|---|
| matchkey_str |
article:0973709X:2021----::rubtetccuclnsnteeiatatfrgatoefodbuahsacruaigeoyesset |
| hierarchy_sort_str |
2021 |
| publishDate |
2021 |
| allfields |
10.7860/JCDR/2021/47750.14824 doi (DE-627)DOAJ058594663 (DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9 DE-627 ger DE-627 rakwb eng Moyurakhi Gogoi verfasserin aut Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. antibiotic susceptibility test phylogenesis streptococcus agalactiae urinary tract infections Medicine R Manuj K Das verfasserin aut Jayanta Kumar Das verfasserin aut Nabanita Barman verfasserin aut Pankaj Das verfasserin aut Utpala Devi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 15(2021), 4, Seite DC13-DC18 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:15 year:2021 number:4 pages:DC13-DC18 https://doi.org/10.7860/JCDR/2021/47750.14824 kostenfrei https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9 kostenfrei https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2021 4 DC13-DC18 |
| spelling |
10.7860/JCDR/2021/47750.14824 doi (DE-627)DOAJ058594663 (DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9 DE-627 ger DE-627 rakwb eng Moyurakhi Gogoi verfasserin aut Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. antibiotic susceptibility test phylogenesis streptococcus agalactiae urinary tract infections Medicine R Manuj K Das verfasserin aut Jayanta Kumar Das verfasserin aut Nabanita Barman verfasserin aut Pankaj Das verfasserin aut Utpala Devi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 15(2021), 4, Seite DC13-DC18 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:15 year:2021 number:4 pages:DC13-DC18 https://doi.org/10.7860/JCDR/2021/47750.14824 kostenfrei https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9 kostenfrei https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2021 4 DC13-DC18 |
| allfields_unstemmed |
10.7860/JCDR/2021/47750.14824 doi (DE-627)DOAJ058594663 (DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9 DE-627 ger DE-627 rakwb eng Moyurakhi Gogoi verfasserin aut Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. antibiotic susceptibility test phylogenesis streptococcus agalactiae urinary tract infections Medicine R Manuj K Das verfasserin aut Jayanta Kumar Das verfasserin aut Nabanita Barman verfasserin aut Pankaj Das verfasserin aut Utpala Devi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 15(2021), 4, Seite DC13-DC18 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:15 year:2021 number:4 pages:DC13-DC18 https://doi.org/10.7860/JCDR/2021/47750.14824 kostenfrei https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9 kostenfrei https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2021 4 DC13-DC18 |
| allfieldsGer |
10.7860/JCDR/2021/47750.14824 doi (DE-627)DOAJ058594663 (DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9 DE-627 ger DE-627 rakwb eng Moyurakhi Gogoi verfasserin aut Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. antibiotic susceptibility test phylogenesis streptococcus agalactiae urinary tract infections Medicine R Manuj K Das verfasserin aut Jayanta Kumar Das verfasserin aut Nabanita Barman verfasserin aut Pankaj Das verfasserin aut Utpala Devi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 15(2021), 4, Seite DC13-DC18 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:15 year:2021 number:4 pages:DC13-DC18 https://doi.org/10.7860/JCDR/2021/47750.14824 kostenfrei https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9 kostenfrei https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2021 4 DC13-DC18 |
| allfieldsSound |
10.7860/JCDR/2021/47750.14824 doi (DE-627)DOAJ058594663 (DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9 DE-627 ger DE-627 rakwb eng Moyurakhi Gogoi verfasserin aut Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. antibiotic susceptibility test phylogenesis streptococcus agalactiae urinary tract infections Medicine R Manuj K Das verfasserin aut Jayanta Kumar Das verfasserin aut Nabanita Barman verfasserin aut Pankaj Das verfasserin aut Utpala Devi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 15(2021), 4, Seite DC13-DC18 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:15 year:2021 number:4 pages:DC13-DC18 https://doi.org/10.7860/JCDR/2021/47750.14824 kostenfrei https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9 kostenfrei https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2021 4 DC13-DC18 |
| language |
English |
| source |
In Journal of Clinical and Diagnostic Research 15(2021), 4, Seite DC13-DC18 volume:15 year:2021 number:4 pages:DC13-DC18 |
| sourceStr |
In Journal of Clinical and Diagnostic Research 15(2021), 4, Seite DC13-DC18 volume:15 year:2021 number:4 pages:DC13-DC18 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
antibiotic susceptibility test phylogenesis streptococcus agalactiae urinary tract infections Medicine R |
| isfreeaccess_bool |
true |
| container_title |
Journal of Clinical and Diagnostic Research |
| authorswithroles_txt_mv |
Moyurakhi Gogoi @@aut@@ Manuj K Das @@aut@@ Jayanta Kumar Das @@aut@@ Nabanita Barman @@aut@@ Pankaj Das @@aut@@ Utpala Devi @@aut@@ |
| publishDateDaySort_date |
2021-01-01T00:00:00Z |
| hierarchy_top_id |
789478048 |
| id |
DOAJ058594663 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ058594663</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230308225333.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.7860/JCDR/2021/47750.14824</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ058594663</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Moyurakhi Gogoi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">antibiotic susceptibility test</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">phylogenesis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">streptococcus agalactiae</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">urinary tract infections</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Manuj K Das</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jayanta Kumar Das</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nabanita Barman</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Pankaj Das</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Utpala Devi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of Clinical and Diagnostic Research</subfield><subfield code="d">JCDR Research and Publications Private Limited, 2009</subfield><subfield code="g">15(2021), 4, Seite DC13-DC18</subfield><subfield code="w">(DE-627)789478048</subfield><subfield code="w">(DE-600)2775283-5</subfield><subfield code="x">0973709X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:15</subfield><subfield code="g">year:2021</subfield><subfield code="g">number:4</subfield><subfield code="g">pages:DC13-DC18</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.7860/JCDR/2021/47750.14824</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2249-782X</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/0973-709X</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">15</subfield><subfield code="j">2021</subfield><subfield code="e">4</subfield><subfield code="h">DC13-DC18</subfield></datafield></record></collection>
|
| author |
Moyurakhi Gogoi |
| spellingShingle |
Moyurakhi Gogoi misc antibiotic susceptibility test misc phylogenesis misc streptococcus agalactiae misc urinary tract infections misc Medicine misc R Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis |
| authorStr |
Moyurakhi Gogoi |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)789478048 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut |
| collection |
DOAJ |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
0973709X |
| topic_title |
Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis antibiotic susceptibility test phylogenesis streptococcus agalactiae urinary tract infections |
| topic |
misc antibiotic susceptibility test misc phylogenesis misc streptococcus agalactiae misc urinary tract infections misc Medicine misc R |
| topic_unstemmed |
misc antibiotic susceptibility test misc phylogenesis misc streptococcus agalactiae misc urinary tract infections misc Medicine misc R |
| topic_browse |
misc antibiotic susceptibility test misc phylogenesis misc streptococcus agalactiae misc urinary tract infections misc Medicine misc R |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Journal of Clinical and Diagnostic Research |
| hierarchy_parent_id |
789478048 |
| hierarchy_top_title |
Journal of Clinical and Diagnostic Research |
| isfreeaccess_txt |
true |
| familylinks_str_mv |
(DE-627)789478048 (DE-600)2775283-5 |
| title |
Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis |
| ctrlnum |
(DE-627)DOAJ058594663 (DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9 |
| title_full |
Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis |
| author_sort |
Moyurakhi Gogoi |
| journal |
Journal of Clinical and Diagnostic Research |
| journalStr |
Journal of Clinical and Diagnostic Research |
| lang_code |
eng |
| isOA_bool |
true |
| recordtype |
marc |
| publishDateSort |
2021 |
| contenttype_str_mv |
txt |
| author_browse |
Moyurakhi Gogoi Manuj K Das Jayanta Kumar Das Nabanita Barman Pankaj Das Utpala Devi |
| container_volume |
15 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Moyurakhi Gogoi |
| doi_str_mv |
10.7860/JCDR/2021/47750.14824 |
| author2-role |
verfasserin |
| title_sort |
group b streptococcus colonising the genital tract of pregnant women from dibrugarh, assam: circulating serotypes, susceptibility pattern and phylogenetic analysis |
| title_auth |
Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis |
| abstract |
Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. |
| abstractGer |
Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. |
| abstract_unstemmed |
Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns. |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 |
| container_issue |
4 |
| title_short |
Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis |
| url |
https://doi.org/10.7860/JCDR/2021/47750.14824 https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9 https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf https://doaj.org/toc/2249-782X https://doaj.org/toc/0973-709X |
| remote_bool |
true |
| author2 |
Manuj K Das Jayanta Kumar Das Nabanita Barman Pankaj Das Utpala Devi |
| author2Str |
Manuj K Das Jayanta Kumar Das Nabanita Barman Pankaj Das Utpala Devi |
| ppnlink |
789478048 |
| mediatype_str_mv |
c |
| isOA_txt |
true |
| hochschulschrift_bool |
false |
| doi_str |
10.7860/JCDR/2021/47750.14824 |
| up_date |
2024-07-03T18:56:50.166Z |
| _version_ |
1803585333687746560 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ058594663</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230308225333.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.7860/JCDR/2021/47750.14824</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ058594663</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ91da200f3484499c8ba0a5b81bf82ff9</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Moyurakhi Gogoi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Group B Streptococcus Colonising the Genital Tract of Pregnant Women from Dibrugarh, Assam: Circulating Serotypes, Susceptibility Pattern and Phylogenetic Analysis</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Introduction: Maternal genitalia colonising bacteria i.e., Group B Streptococcus (GBS) well known as Streptococcus agalactiae is responsible for serious health complications in newborns like sepsis, meningitis and pneumonitis. Centre for Disease Control and Prevention (CDC) recommends a thorough culture based screening in 35-37 weeks gestation mothers for further therapeutic steps. Previously no study was carried out on the occurrence of GBS among pregnant mothers in Assam with phylogenetic analysis. Aim: To bring the scenario of GBS infection in antepartum women by targeting the capsular serotypes with their antibiogram profile and to bring the phylogenetic relationship of the prevailing GBS isolates found in Dibrugarh district, Assam, India. Materials and Methods: This was a hospital based observational study which was carried out in District Urban Health Centre, Assam, India. Lower vaginal swabs without using speculum were collected from the enrolled late trimester pregnant women. Socio-demographic data were collected with their consent. Out of the total enrolled participants (n=345), GBS was isolated in 52 samples. These were inspected by culture techniques and further confirmed using molecular methods. Serotyping was carried out by employing multiplex PCR. Antibiotic susceptibility test was conducted as per Clinical and Laboratory Standards Institute (CLSI) guidelines and phylogenetic tree was reconstructed. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 16.0. Results: This study showed a GBS carriage rate of 15.1% in the colonising participating women. No significant association with any of the demographic and clinical factors was found. Serotype Ia (42.1%) was the ruling one followed by VI (31.6%), II (15.8%) and VII (10.5%). While 36.7% of the GBS isolates were grouped into not typeable. Serotypes Ia showed resistant towards cefotaxime, erythromycin and clindamycin and serotype II towards vancomycin. Phylogenetic evaluation showed the presence of four distinct clusters viz., I, II, III and IV with unique evolutionary trends in human GBS population in the study site. Conclusion: So far in Assam, this study reports for the first time on GBS prevailing rate in late trimester mothers which may be helpful in declining the rate of adverse neonatal outcomes with on time maternal therapeutic administration by real time monitoring of antibiogram profiling. This study also paves a way of designing Capsular Polysaccharide (CPS) based vaccines for immunising the expectant mothers to prevent adverse outcomes of the newborns.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">antibiotic susceptibility test</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">phylogenesis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">streptococcus agalactiae</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">urinary tract infections</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Manuj K Das</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jayanta Kumar Das</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nabanita Barman</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Pankaj Das</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Utpala Devi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of Clinical and Diagnostic Research</subfield><subfield code="d">JCDR Research and Publications Private Limited, 2009</subfield><subfield code="g">15(2021), 4, Seite DC13-DC18</subfield><subfield code="w">(DE-627)789478048</subfield><subfield code="w">(DE-600)2775283-5</subfield><subfield code="x">0973709X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:15</subfield><subfield code="g">year:2021</subfield><subfield code="g">number:4</subfield><subfield code="g">pages:DC13-DC18</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.7860/JCDR/2021/47750.14824</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/91da200f3484499c8ba0a5b81bf82ff9</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.jcdr.net/articles/PDF/14824/47750_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2249-782X</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/0973-709X</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">15</subfield><subfield code="j">2021</subfield><subfield code="e">4</subfield><subfield code="h">DC13-DC18</subfield></datafield></record></collection>
|
| score |
7.4006968 |