A rare case of acute myeloid leukemia with t(12;19)(q13;q13)

Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(1...
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Autor*in:	Alain Chebly [verfasserIn] Fady Gh Haddad [verfasserIn] Josiane Bassil [verfasserIn] Tony Yammine [verfasserIn] Rima Korban [verfasserIn] Warde Semaan [verfasserIn] Fady El Karak [verfasserIn] Hampig Raphael Kourie [verfasserIn] Chantal Farra [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype

Übergeordnetes Werk:	In: Leukemia Research Reports - Elsevier, 2015, 14(2020), Seite 100216-
Übergeordnetes Werk:	volume:14 ; year:2020 ; pages:100216-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.lrr.2020.100216

Katalog-ID:	DOAJ058828710

Internformat


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520			\|a Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML.
650		4	\|a Acute myeloid leukemia
650		4	\|a AML
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650		4	\|a t(12;19)
650		4	\|a Cytogenetic
650		4	\|a Karyotype
653		0	\|a Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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publishDate	2020
allfields	10.1016/j.lrr.2020.100216 doi (DE-627)DOAJ058828710 (DE-599)DOAJ8574c7fabfed474d990f4cc2712c5ce6 DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut A rare case of acute myeloid leukemia with t(12;19)(q13;q13) 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML. Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype Neoplasms. Tumors. Oncology. Including cancer and carcinogens Fady Gh Haddad verfasserin aut Josiane Bassil verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Fady El Karak verfasserin aut Hampig Raphael Kourie verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 14(2020), Seite 100216- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:14 year:2020 pages:100216- https://doi.org/10.1016/j.lrr.2020.100216 kostenfrei https://doaj.org/article/8574c7fabfed474d990f4cc2712c5ce6 kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048920300224 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2020 100216-
spelling	10.1016/j.lrr.2020.100216 doi (DE-627)DOAJ058828710 (DE-599)DOAJ8574c7fabfed474d990f4cc2712c5ce6 DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut A rare case of acute myeloid leukemia with t(12;19)(q13;q13) 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML. Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype Neoplasms. Tumors. Oncology. Including cancer and carcinogens Fady Gh Haddad verfasserin aut Josiane Bassil verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Fady El Karak verfasserin aut Hampig Raphael Kourie verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 14(2020), Seite 100216- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:14 year:2020 pages:100216- https://doi.org/10.1016/j.lrr.2020.100216 kostenfrei https://doaj.org/article/8574c7fabfed474d990f4cc2712c5ce6 kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048920300224 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2020 100216-
allfields_unstemmed	10.1016/j.lrr.2020.100216 doi (DE-627)DOAJ058828710 (DE-599)DOAJ8574c7fabfed474d990f4cc2712c5ce6 DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut A rare case of acute myeloid leukemia with t(12;19)(q13;q13) 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML. Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype Neoplasms. Tumors. Oncology. Including cancer and carcinogens Fady Gh Haddad verfasserin aut Josiane Bassil verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Fady El Karak verfasserin aut Hampig Raphael Kourie verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 14(2020), Seite 100216- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:14 year:2020 pages:100216- https://doi.org/10.1016/j.lrr.2020.100216 kostenfrei https://doaj.org/article/8574c7fabfed474d990f4cc2712c5ce6 kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048920300224 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2020 100216-
allfieldsGer	10.1016/j.lrr.2020.100216 doi (DE-627)DOAJ058828710 (DE-599)DOAJ8574c7fabfed474d990f4cc2712c5ce6 DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut A rare case of acute myeloid leukemia with t(12;19)(q13;q13) 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML. Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype Neoplasms. Tumors. Oncology. Including cancer and carcinogens Fady Gh Haddad verfasserin aut Josiane Bassil verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Fady El Karak verfasserin aut Hampig Raphael Kourie verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 14(2020), Seite 100216- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:14 year:2020 pages:100216- https://doi.org/10.1016/j.lrr.2020.100216 kostenfrei https://doaj.org/article/8574c7fabfed474d990f4cc2712c5ce6 kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048920300224 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2020 100216-
allfieldsSound	10.1016/j.lrr.2020.100216 doi (DE-627)DOAJ058828710 (DE-599)DOAJ8574c7fabfed474d990f4cc2712c5ce6 DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut A rare case of acute myeloid leukemia with t(12;19)(q13;q13) 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML. Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype Neoplasms. Tumors. Oncology. Including cancer and carcinogens Fady Gh Haddad verfasserin aut Josiane Bassil verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Fady El Karak verfasserin aut Hampig Raphael Kourie verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 14(2020), Seite 100216- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:14 year:2020 pages:100216- https://doi.org/10.1016/j.lrr.2020.100216 kostenfrei https://doaj.org/article/8574c7fabfed474d990f4cc2712c5ce6 kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048920300224 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2020 100216-
language	English
source	In Leukemia Research Reports 14(2020), Seite 100216- volume:14 year:2020 pages:100216-
sourceStr	In Leukemia Research Reports 14(2020), Seite 100216- volume:14 year:2020 pages:100216-
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype Neoplasms. Tumors. Oncology. Including cancer and carcinogens
isfreeaccess_bool	true
container_title	Leukemia Research Reports
authorswithroles_txt_mv	Alain Chebly @@aut@@ Fady Gh Haddad @@aut@@ Josiane Bassil @@aut@@ Tony Yammine @@aut@@ Rima Korban @@aut@@ Warde Semaan @@aut@@ Fady El Karak @@aut@@ Hampig Raphael Kourie @@aut@@ Chantal Farra @@aut@@
publishDateDaySort_date	2020-01-01T00:00:00Z
hierarchy_top_id	738404586
id	DOAJ058828710
language_de	englisch
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callnumber-first	R - Medicine
author	Alain Chebly
spellingShingle	Alain Chebly misc RC254-282 misc Acute myeloid leukemia misc AML misc M5 misc t(12;19) misc Cytogenetic misc Karyotype misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens A rare case of acute myeloid leukemia with t(12;19)(q13;q13)
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topic_title	RC254-282 A rare case of acute myeloid leukemia with t(12;19)(q13;q13) Acute myeloid leukemia AML M5 t(12;19) Cytogenetic Karyotype
topic	misc RC254-282 misc Acute myeloid leukemia misc AML misc M5 misc t(12;19) misc Cytogenetic misc Karyotype misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RC254-282 misc Acute myeloid leukemia misc AML misc M5 misc t(12;19) misc Cytogenetic misc Karyotype misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	A rare case of acute myeloid leukemia with t(12;19)(q13;q13)
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title_full	A rare case of acute myeloid leukemia with t(12;19)(q13;q13)
author_sort	Alain Chebly
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author_browse	Alain Chebly Fady Gh Haddad Josiane Bassil Tony Yammine Rima Korban Warde Semaan Fady El Karak Hampig Raphael Kourie Chantal Farra
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title_sort	rare case of acute myeloid leukemia with t(12;19)(q13;q13)
callnumber	RC254-282
title_auth	A rare case of acute myeloid leukemia with t(12;19)(q13;q13)
abstract	Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML.
abstractGer	Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML.
abstract_unstemmed	Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We herein, report a rare balanced translocation t(12;19)(q13;q13) in a 66-year old M5-AML patient identified by Conventional cytogenetic analysis and confirmed by SNP array. We suggest that t(12;19) as a sole chromosomal abnormality could be associated with a poor prognosis. Further studies are needed to understand the molecular basis of this translocation in AML.
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title_short	A rare case of acute myeloid leukemia with t(12;19)(q13;q13)
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up_date	2024-07-03T20:18:01.602Z
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A rare case of acute myeloid leukemia with t(12;19)(q13;q13)

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Vorhandene Bände

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