Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases

<p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p< Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ingrosso Gianluca [verfasserIn] Miceli Roberto [verfasserIn] Fedele Dahlia [verfasserIn] Ponti Elisabetta [verfasserIn] Benassi Michaela [verfasserIn] Barbarino Rosaria [verfasserIn] Di Murro Luana [verfasserIn] Giudice Emilia [verfasserIn] Santarelli Federico [verfasserIn] Santoni Riccardo [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2012

Übergeordnetes Werk:	In: Radiation Oncology - BMC, 2006, 7(2012), 1, p 54
Übergeordnetes Werk:	volume:7 ; year:2012 ; number:1, p 54

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/1748-717X-7-54

Katalog-ID:	DOAJ058868887

Internformat


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245	1	0	\|a Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
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520			\|a <p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p<
653		0	\|a Medical physics. Medical radiology. Nuclear medicine
653		0	\|a Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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author_variant	i g ig m r mr f d fd p e pe b m bm b r br d m l dml g e ge s f sf s r sr
matchkey_str	article:1748717X:2012----::oeemoptdoorpynyorcintdtroatcait
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allfields	10.1186/1748-717X-7-54 doi (DE-627)DOAJ058868887 (DE-599)DOAJ9c6ff9886015492d99db1ee180136bf5 DE-627 ger DE-627 rakwb eng R895-920 RC254-282 Ingrosso Gianluca verfasserin aut Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p< Medical physics. Medical radiology. Nuclear medicine Neoplasms. Tumors. Oncology. Including cancer and carcinogens Miceli Roberto verfasserin aut Fedele Dahlia verfasserin aut Ponti Elisabetta verfasserin aut Benassi Michaela verfasserin aut Barbarino Rosaria verfasserin aut Di Murro Luana verfasserin aut Giudice Emilia verfasserin aut Santarelli Federico verfasserin aut Santoni Riccardo verfasserin aut In Radiation Oncology BMC, 2006 7(2012), 1, p 54 (DE-627)508725739 (DE-600)2224965-5 1748717X nnns volume:7 year:2012 number:1, p 54 https://doi.org/10.1186/1748-717X-7-54 kostenfrei https://doaj.org/article/9c6ff9886015492d99db1ee180136bf5 kostenfrei http://www.ro-journal.com/content/7/1/54 kostenfrei https://doaj.org/toc/1748-717X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2012 1, p 54
spelling	10.1186/1748-717X-7-54 doi (DE-627)DOAJ058868887 (DE-599)DOAJ9c6ff9886015492d99db1ee180136bf5 DE-627 ger DE-627 rakwb eng R895-920 RC254-282 Ingrosso Gianluca verfasserin aut Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p< Medical physics. Medical radiology. Nuclear medicine Neoplasms. Tumors. Oncology. Including cancer and carcinogens Miceli Roberto verfasserin aut Fedele Dahlia verfasserin aut Ponti Elisabetta verfasserin aut Benassi Michaela verfasserin aut Barbarino Rosaria verfasserin aut Di Murro Luana verfasserin aut Giudice Emilia verfasserin aut Santarelli Federico verfasserin aut Santoni Riccardo verfasserin aut In Radiation Oncology BMC, 2006 7(2012), 1, p 54 (DE-627)508725739 (DE-600)2224965-5 1748717X nnns volume:7 year:2012 number:1, p 54 https://doi.org/10.1186/1748-717X-7-54 kostenfrei https://doaj.org/article/9c6ff9886015492d99db1ee180136bf5 kostenfrei http://www.ro-journal.com/content/7/1/54 kostenfrei https://doaj.org/toc/1748-717X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2012 1, p 54
allfields_unstemmed	10.1186/1748-717X-7-54 doi (DE-627)DOAJ058868887 (DE-599)DOAJ9c6ff9886015492d99db1ee180136bf5 DE-627 ger DE-627 rakwb eng R895-920 RC254-282 Ingrosso Gianluca verfasserin aut Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p< Medical physics. Medical radiology. Nuclear medicine Neoplasms. Tumors. Oncology. Including cancer and carcinogens Miceli Roberto verfasserin aut Fedele Dahlia verfasserin aut Ponti Elisabetta verfasserin aut Benassi Michaela verfasserin aut Barbarino Rosaria verfasserin aut Di Murro Luana verfasserin aut Giudice Emilia verfasserin aut Santarelli Federico verfasserin aut Santoni Riccardo verfasserin aut In Radiation Oncology BMC, 2006 7(2012), 1, p 54 (DE-627)508725739 (DE-600)2224965-5 1748717X nnns volume:7 year:2012 number:1, p 54 https://doi.org/10.1186/1748-717X-7-54 kostenfrei https://doaj.org/article/9c6ff9886015492d99db1ee180136bf5 kostenfrei http://www.ro-journal.com/content/7/1/54 kostenfrei https://doaj.org/toc/1748-717X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2012 1, p 54
allfieldsGer	10.1186/1748-717X-7-54 doi (DE-627)DOAJ058868887 (DE-599)DOAJ9c6ff9886015492d99db1ee180136bf5 DE-627 ger DE-627 rakwb eng R895-920 RC254-282 Ingrosso Gianluca verfasserin aut Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p< Medical physics. Medical radiology. Nuclear medicine Neoplasms. Tumors. Oncology. Including cancer and carcinogens Miceli Roberto verfasserin aut Fedele Dahlia verfasserin aut Ponti Elisabetta verfasserin aut Benassi Michaela verfasserin aut Barbarino Rosaria verfasserin aut Di Murro Luana verfasserin aut Giudice Emilia verfasserin aut Santarelli Federico verfasserin aut Santoni Riccardo verfasserin aut In Radiation Oncology BMC, 2006 7(2012), 1, p 54 (DE-627)508725739 (DE-600)2224965-5 1748717X nnns volume:7 year:2012 number:1, p 54 https://doi.org/10.1186/1748-717X-7-54 kostenfrei https://doaj.org/article/9c6ff9886015492d99db1ee180136bf5 kostenfrei http://www.ro-journal.com/content/7/1/54 kostenfrei https://doaj.org/toc/1748-717X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2012 1, p 54
allfieldsSound	10.1186/1748-717X-7-54 doi (DE-627)DOAJ058868887 (DE-599)DOAJ9c6ff9886015492d99db1ee180136bf5 DE-627 ger DE-627 rakwb eng R895-920 RC254-282 Ingrosso Gianluca verfasserin aut Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p< Medical physics. Medical radiology. Nuclear medicine Neoplasms. Tumors. Oncology. Including cancer and carcinogens Miceli Roberto verfasserin aut Fedele Dahlia verfasserin aut Ponti Elisabetta verfasserin aut Benassi Michaela verfasserin aut Barbarino Rosaria verfasserin aut Di Murro Luana verfasserin aut Giudice Emilia verfasserin aut Santarelli Federico verfasserin aut Santoni Riccardo verfasserin aut In Radiation Oncology BMC, 2006 7(2012), 1, p 54 (DE-627)508725739 (DE-600)2224965-5 1748717X nnns volume:7 year:2012 number:1, p 54 https://doi.org/10.1186/1748-717X-7-54 kostenfrei https://doaj.org/article/9c6ff9886015492d99db1ee180136bf5 kostenfrei http://www.ro-journal.com/content/7/1/54 kostenfrei https://doaj.org/toc/1748-717X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2012 1, p 54
language	English
source	In Radiation Oncology 7(2012), 1, p 54 volume:7 year:2012 number:1, p 54
sourceStr	In Radiation Oncology 7(2012), 1, p 54 volume:7 year:2012 number:1, p 54
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Medical physics. Medical radiology. Nuclear medicine Neoplasms. Tumors. Oncology. Including cancer and carcinogens
isfreeaccess_bool	true
container_title	Radiation Oncology
authorswithroles_txt_mv	Ingrosso Gianluca @@aut@@ Miceli Roberto @@aut@@ Fedele Dahlia @@aut@@ Ponti Elisabetta @@aut@@ Benassi Michaela @@aut@@ Barbarino Rosaria @@aut@@ Di Murro Luana @@aut@@ Giudice Emilia @@aut@@ Santarelli Federico @@aut@@ Santoni Riccardo @@aut@@
publishDateDaySort_date	2012-01-01T00:00:00Z
hierarchy_top_id	508725739
id	DOAJ058868887
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ058868887</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230503030832.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2012 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1186/1748-717X-7-54</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ058868887</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ9c6ff9886015492d99db1ee180136bf5</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">R895-920</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC254-282</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Ingrosso Gianluca</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2012</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a"><p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p<</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medical physics. Medical radiology. Nuclear medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neoplasms. Tumors. Oncology. 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callnumber-first	R - Medicine
author	Ingrosso Gianluca
spellingShingle	Ingrosso Gianluca misc R895-920 misc RC254-282 misc Medical physics. Medical radiology. Nuclear medicine misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
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topic_title	R895-920 RC254-282 Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
topic	misc R895-920 misc RC254-282 misc Medical physics. Medical radiology. Nuclear medicine misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc R895-920 misc RC254-282 misc Medical physics. Medical radiology. Nuclear medicine misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
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title_full	Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
author_sort	Ingrosso Gianluca
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author_browse	Ingrosso Gianluca Miceli Roberto Fedele Dahlia Ponti Elisabetta Benassi Michaela Barbarino Rosaria Di Murro Luana Giudice Emilia Santarelli Federico Santoni Riccardo
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author2-role	verfasserin
title_sort	cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
callnumber	R895-920
title_auth	Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
abstract	<p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p<
abstractGer	<p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p<
abstract_unstemmed	<p<Abstract</p< <p<Background</p< <p<To assess interfraction translational and rotational setup errors, in patients treated with image-guded hypofractionated stereotactic radiotherapy, immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates.</p< <p<Methods</p< <p<37 patients with 47 brain metastases were treated with hypofractionated stererotactic radiotherapy. All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p<
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title_short	Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases
url	https://doi.org/10.1186/1748-717X-7-54 https://doaj.org/article/9c6ff9886015492d99db1ee180136bf5 http://www.ro-journal.com/content/7/1/54 https://doaj.org/toc/1748-717X
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up_date	2024-07-03T20:31:09.431Z
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All patients were immobilized with a combination of a thermoplastic mask and a bite-block fixed to a stereotactic frame support. Daily cone-beam CT scans were acquired for every patient before the treatment session and were matched online with planning CT images, for 3D image registration. The mean value and standard deviation of all translational (X, Y, Z) and rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were calculated for the matching results of bone matching algorithm.</p< <p<Results</p< <p<A total of 194 CBCT scans were analyzed. Mean +/- standard deviation of translational errors (X, Y, Z) were respectively 0.5 +/- 1.6 mm (range -5.7 and 5.9 mm) in X; 0.4 +/- 2.7 mm (range -8.2 and 12.1 mm) in Y; 0.4 +/- 1.9 mm (range -7.0 and 14 mm) in Z; median and 90th percentile were respectively within 0.5 mm and 2.4 mm in X, 0.3 mm and 3.2 mm in Y, 0.3 mm and 2.2 mm in Z. Mean +/- standard deviation of rotational errors (θ<sub<x</sub<, θy, θ<sub<z</sub<) were respectively 0.0 degrees+/- 1.3 degrees (θ<sub<x</sub<) (range -6.0 degrees and 3.1 degrees); -0.1 degrees +/- 1.1 degrees (θy) (range -3.0 degrees and 2.4 degrees); -0.6 degrees +/- 1.4 degrees (θ<sub<z</sub<) (range -5.0 degrees and 3.3 degrees). Median and 90th percentile of rotational errors were respectively within 0.1 degrees and 1.4 degrees (θ<sub<x</sub<), 0.0 degrees and 1.2 degrees (θy), 0.0 degrees and 0.9 degrees (θ<sub<z</sub<). Mean +/- SD of 3D vector was 3.1 +/- 2.1 mm (range 0.3 and 14.9 mm); median and 90th percentile of 3D vector was within 2.7 mm and 5.1 mm.</p< <p<Conclusions</p< <p<Hypofractionated stereotactic radiotherapy have the significant limitation of uncertainty in interfraction repeatability of the patient setup; image-guided radiotherapy using cone-beam computed tomography improves the accuracy of the treatment delivery reducing set-up uncertainty, giving the possibility of 3-dimensional anatomic informations in the treatment position.</p<</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medical physics. Medical radiology. Nuclear medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neoplasms. Tumors. Oncology. 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Cone-beam computed tomography in hypofractionated stereotactic radiotherapy for brain metastases

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