The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism

Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ekrem Şahan [verfasserIn] Murat Karamanlıoğlu [verfasserIn] Suzan Şahan [verfasserIn] Murat Gül [verfasserIn] Ahmet Korkmaz [verfasserIn] Omaç Tüfekçioğlu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch ; Türkisch

Erschienen:	2017

Schlagwörter:	echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function.

Übergeordnetes Werk:	In: Türk Kardiyoloji Derneği Arşivi - KARE Publishing, 2018, 45(2017), 8, Seite 709-714
Übergeordnetes Werk:	volume:45 ; year:2017 ; number:8 ; pages:709-714

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.5543/tkda.2017.94694

Katalog-ID:	DOAJ058992626

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520			\|a Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE.
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allfields	10.5543/tkda.2017.94694 doi (DE-627)DOAJ058992626 (DE-599)DOAJ2d0d19809e324d2ba8ac0c05e92762c8 DE-627 ger DE-627 rakwb eng tur RC31-1245 RC666-701 Ekrem Şahan verfasserin aut The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE. echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. Medicine R Internal medicine Diseases of the circulatory (Cardiovascular) system Murat Karamanlıoğlu verfasserin aut Suzan Şahan verfasserin aut Murat Gül verfasserin aut Ahmet Korkmaz verfasserin aut Omaç Tüfekçioğlu verfasserin aut In Türk Kardiyoloji Derneği Arşivi KARE Publishing, 2018 45(2017), 8, Seite 709-714 (DE-627)599239808 (DE-600)2492682-6 10165169 nnns volume:45 year:2017 number:8 pages:709-714 https://doi.org/10.5543/tkda.2017.94694 kostenfrei https://doaj.org/article/2d0d19809e324d2ba8ac0c05e92762c8 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-94694 kostenfrei https://doaj.org/toc/1016-5169 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 45 2017 8 709-714
spelling	10.5543/tkda.2017.94694 doi (DE-627)DOAJ058992626 (DE-599)DOAJ2d0d19809e324d2ba8ac0c05e92762c8 DE-627 ger DE-627 rakwb eng tur RC31-1245 RC666-701 Ekrem Şahan verfasserin aut The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE. echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. Medicine R Internal medicine Diseases of the circulatory (Cardiovascular) system Murat Karamanlıoğlu verfasserin aut Suzan Şahan verfasserin aut Murat Gül verfasserin aut Ahmet Korkmaz verfasserin aut Omaç Tüfekçioğlu verfasserin aut In Türk Kardiyoloji Derneği Arşivi KARE Publishing, 2018 45(2017), 8, Seite 709-714 (DE-627)599239808 (DE-600)2492682-6 10165169 nnns volume:45 year:2017 number:8 pages:709-714 https://doi.org/10.5543/tkda.2017.94694 kostenfrei https://doaj.org/article/2d0d19809e324d2ba8ac0c05e92762c8 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-94694 kostenfrei https://doaj.org/toc/1016-5169 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 45 2017 8 709-714
allfields_unstemmed	10.5543/tkda.2017.94694 doi (DE-627)DOAJ058992626 (DE-599)DOAJ2d0d19809e324d2ba8ac0c05e92762c8 DE-627 ger DE-627 rakwb eng tur RC31-1245 RC666-701 Ekrem Şahan verfasserin aut The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE. echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. Medicine R Internal medicine Diseases of the circulatory (Cardiovascular) system Murat Karamanlıoğlu verfasserin aut Suzan Şahan verfasserin aut Murat Gül verfasserin aut Ahmet Korkmaz verfasserin aut Omaç Tüfekçioğlu verfasserin aut In Türk Kardiyoloji Derneği Arşivi KARE Publishing, 2018 45(2017), 8, Seite 709-714 (DE-627)599239808 (DE-600)2492682-6 10165169 nnns volume:45 year:2017 number:8 pages:709-714 https://doi.org/10.5543/tkda.2017.94694 kostenfrei https://doaj.org/article/2d0d19809e324d2ba8ac0c05e92762c8 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-94694 kostenfrei https://doaj.org/toc/1016-5169 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 45 2017 8 709-714
allfieldsGer	10.5543/tkda.2017.94694 doi (DE-627)DOAJ058992626 (DE-599)DOAJ2d0d19809e324d2ba8ac0c05e92762c8 DE-627 ger DE-627 rakwb eng tur RC31-1245 RC666-701 Ekrem Şahan verfasserin aut The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE. echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. Medicine R Internal medicine Diseases of the circulatory (Cardiovascular) system Murat Karamanlıoğlu verfasserin aut Suzan Şahan verfasserin aut Murat Gül verfasserin aut Ahmet Korkmaz verfasserin aut Omaç Tüfekçioğlu verfasserin aut In Türk Kardiyoloji Derneği Arşivi KARE Publishing, 2018 45(2017), 8, Seite 709-714 (DE-627)599239808 (DE-600)2492682-6 10165169 nnns volume:45 year:2017 number:8 pages:709-714 https://doi.org/10.5543/tkda.2017.94694 kostenfrei https://doaj.org/article/2d0d19809e324d2ba8ac0c05e92762c8 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-94694 kostenfrei https://doaj.org/toc/1016-5169 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 45 2017 8 709-714
allfieldsSound	10.5543/tkda.2017.94694 doi (DE-627)DOAJ058992626 (DE-599)DOAJ2d0d19809e324d2ba8ac0c05e92762c8 DE-627 ger DE-627 rakwb eng tur RC31-1245 RC666-701 Ekrem Şahan verfasserin aut The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE. echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. Medicine R Internal medicine Diseases of the circulatory (Cardiovascular) system Murat Karamanlıoğlu verfasserin aut Suzan Şahan verfasserin aut Murat Gül verfasserin aut Ahmet Korkmaz verfasserin aut Omaç Tüfekçioğlu verfasserin aut In Türk Kardiyoloji Derneği Arşivi KARE Publishing, 2018 45(2017), 8, Seite 709-714 (DE-627)599239808 (DE-600)2492682-6 10165169 nnns volume:45 year:2017 number:8 pages:709-714 https://doi.org/10.5543/tkda.2017.94694 kostenfrei https://doaj.org/article/2d0d19809e324d2ba8ac0c05e92762c8 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-94694 kostenfrei https://doaj.org/toc/1016-5169 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 45 2017 8 709-714
language	English Turkish
source	In Türk Kardiyoloji Derneği Arşivi 45(2017), 8, Seite 709-714 volume:45 year:2017 number:8 pages:709-714
sourceStr	In Türk Kardiyoloji Derneği Arşivi 45(2017), 8, Seite 709-714 volume:45 year:2017 number:8 pages:709-714
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. Medicine R Internal medicine Diseases of the circulatory (Cardiovascular) system
isfreeaccess_bool	true
container_title	Türk Kardiyoloji Derneği Arşivi
authorswithroles_txt_mv	Ekrem Şahan @@aut@@ Murat Karamanlıoğlu @@aut@@ Suzan Şahan @@aut@@ Murat Gül @@aut@@ Ahmet Korkmaz @@aut@@ Omaç Tüfekçioğlu @@aut@@
publishDateDaySort_date	2017-01-01T00:00:00Z
hierarchy_top_id	599239808
id	DOAJ058992626
language_de	englisch türkisch
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Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. 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author	Ekrem Şahan
spellingShingle	Ekrem Şahan misc RC31-1245 misc RC666-701 misc echocardiography misc fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. misc Medicine misc R misc Internal medicine misc Diseases of the circulatory (Cardiovascular) system The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism
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topic_title	RC31-1245 RC666-701 The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism echocardiography fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function
topic	misc RC31-1245 misc RC666-701 misc echocardiography misc fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. misc Medicine misc R misc Internal medicine misc Diseases of the circulatory (Cardiovascular) system
topic_unstemmed	misc RC31-1245 misc RC666-701 misc echocardiography misc fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. misc Medicine misc R misc Internal medicine misc Diseases of the circulatory (Cardiovascular) system
topic_browse	misc RC31-1245 misc RC666-701 misc echocardiography misc fractional shortening; pulmonary embolism; pulmonary embolism severity index; right ventricular function. misc Medicine misc R misc Internal medicine misc Diseases of the circulatory (Cardiovascular) system
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title	The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism
ctrlnum	(DE-627)DOAJ058992626 (DE-599)DOAJ2d0d19809e324d2ba8ac0c05e92762c8
title_full	The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism
author_sort	Ekrem Şahan
journal	Türk Kardiyoloji Derneği Arşivi
journalStr	Türk Kardiyoloji Derneği Arşivi
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author_browse	Ekrem Şahan Murat Karamanlıoğlu Suzan Şahan Murat Gül Ahmet Korkmaz Omaç Tüfekçioğlu
container_volume	45
class	RC31-1245 RC666-701
format_se	Elektronische Aufsätze
author-letter	Ekrem Şahan
doi_str_mv	10.5543/tkda.2017.94694
author2-role	verfasserin
title_sort	relationship between right ventricular outflow tract fractional shortening and pulmonary embolism severity index in acute pulmonary embolism
callnumber	RC31-1245
title_auth	The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism
abstract	Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE.
abstractGer	Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE.
abstract_unstemmed	Objective: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). Methods: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. Results: Mean age was similar between sPESI <1 and <1 patients (58.7+-12.9 years vs. 61.1+-12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41+-3.56 vs. 22.98+-4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). Conclusion: The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE.
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title_short	The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism
url	https://doi.org/10.5543/tkda.2017.94694 https://doaj.org/article/2d0d19809e324d2ba8ac0c05e92762c8 https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-94694 https://doaj.org/toc/1016-5169
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author2	Murat Karamanlıoğlu Suzan Şahan Murat Gül Ahmet Korkmaz Omaç Tüfekçioğlu
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up_date	2024-07-03T21:12:21.976Z
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