In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules

<b< </b<Hemocompatibility is an essential prerequisite for the application of materials in the field of biomedicine and biosensing. In addition, mixed ionic and electronic conductivity of conducting polymers is an advantageous property for these applications. Heparin-like materials conta...
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Autor*in:	Kateřina Skopalová [verfasserIn] Zdenka Capáková [verfasserIn] Patrycja Bober [verfasserIn] Jana Pelková [verfasserIn] Jaroslav Stejskal [verfasserIn] Věra Kašpárková [verfasserIn] Marián Lehocký [verfasserIn] Ita Junkar [verfasserIn] Miran Mozetič [verfasserIn] Petr Humpolíček [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	polymer conductivity conducting polymer polyaniline hemocompatibility

Übergeordnetes Werk:	In: Polymers - MDPI AG, 2011, 11(2019), 11, p 1861
Übergeordnetes Werk:	volume:11 ; year:2019 ; number:11, p 1861

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/polym11111861

Katalog-ID:	DOAJ059260742

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allfieldsSound	10.3390/polym11111861 doi (DE-627)DOAJ059260742 (DE-599)DOAJd481bc54d1d14092ad4044fad1b2de10 DE-627 ger DE-627 rakwb eng QD241-441 Kateřina Skopalová verfasserin aut In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <b< </b<Hemocompatibility is an essential prerequisite for the application of materials in the field of biomedicine and biosensing. In addition, mixed ionic and electronic conductivity of conducting polymers is an advantageous property for these applications. Heparin-like materials containing sulfate, sulfamic, and carboxylic groups may have an anticoagulation effect. Therefore, sodium dodecylbenzenesulfonate, 2-aminoethane-1-sulfonic acid and <i<N</i<-(2-acetamido)-2-aminoethanesulfonic acid were used for modification of the representative of conducting polymers, polyaniline, and the resulting products were studied in the context of interactions with human blood. The anticoagulation activity was then correlated to surface energy and conductivity of the materials. Results show that anticoagulation activity is highly affected by the presence of suitable functional groups originating from the used heparin-like substances, and by the properties of polyaniline polymer itself. polymer conductivity conducting polymer polyaniline hemocompatibility Organic chemistry Zdenka Capáková verfasserin aut Patrycja Bober verfasserin aut Jana Pelková verfasserin aut Jaroslav Stejskal verfasserin aut Věra Kašpárková verfasserin aut Marián Lehocký verfasserin aut Ita Junkar verfasserin aut Miran Mozetič verfasserin aut Petr Humpolíček verfasserin aut In Polymers MDPI AG, 2011 11(2019), 11, p 1861 (DE-627)61409612X (DE-600)2527146-5 20734360 nnns volume:11 year:2019 number:11, p 1861 https://doi.org/10.3390/polym11111861 kostenfrei https://doaj.org/article/d481bc54d1d14092ad4044fad1b2de10 kostenfrei https://www.mdpi.com/2073-4360/11/11/1861 kostenfrei https://doaj.org/toc/2073-4360 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2019 11, p 1861
language	English
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topic_facet	polymer conductivity conducting polymer polyaniline hemocompatibility Organic chemistry
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container_title	Polymers
authorswithroles_txt_mv	Kateřina Skopalová @@aut@@ Zdenka Capáková @@aut@@ Patrycja Bober @@aut@@ Jana Pelková @@aut@@ Jaroslav Stejskal @@aut@@ Věra Kašpárková @@aut@@ Marián Lehocký @@aut@@ Ita Junkar @@aut@@ Miran Mozetič @@aut@@ Petr Humpolíček @@aut@@
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callnumber-first	Q - Science
author	Kateřina Skopalová
spellingShingle	Kateřina Skopalová misc QD241-441 misc polymer conductivity misc conducting polymer misc polyaniline misc hemocompatibility misc Organic chemistry In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules
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topic_title	QD241-441 In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules polymer conductivity conducting polymer polyaniline hemocompatibility
topic	misc QD241-441 misc polymer conductivity misc conducting polymer misc polyaniline misc hemocompatibility misc Organic chemistry
topic_unstemmed	misc QD241-441 misc polymer conductivity misc conducting polymer misc polyaniline misc hemocompatibility misc Organic chemistry
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title	In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules
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title_full	In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules
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author_browse	Kateřina Skopalová Zdenka Capáková Patrycja Bober Jana Pelková Jaroslav Stejskal Věra Kašpárková Marián Lehocký Ita Junkar Miran Mozetič Petr Humpolíček
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title_sort	in-vitro hemocompatibility of polyaniline functionalized by bioactive molecules
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title_auth	In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules
abstract	<b< </b<Hemocompatibility is an essential prerequisite for the application of materials in the field of biomedicine and biosensing. In addition, mixed ionic and electronic conductivity of conducting polymers is an advantageous property for these applications. Heparin-like materials containing sulfate, sulfamic, and carboxylic groups may have an anticoagulation effect. Therefore, sodium dodecylbenzenesulfonate, 2-aminoethane-1-sulfonic acid and <i<N</i<-(2-acetamido)-2-aminoethanesulfonic acid were used for modification of the representative of conducting polymers, polyaniline, and the resulting products were studied in the context of interactions with human blood. The anticoagulation activity was then correlated to surface energy and conductivity of the materials. Results show that anticoagulation activity is highly affected by the presence of suitable functional groups originating from the used heparin-like substances, and by the properties of polyaniline polymer itself.
abstractGer	<b< </b<Hemocompatibility is an essential prerequisite for the application of materials in the field of biomedicine and biosensing. In addition, mixed ionic and electronic conductivity of conducting polymers is an advantageous property for these applications. Heparin-like materials containing sulfate, sulfamic, and carboxylic groups may have an anticoagulation effect. Therefore, sodium dodecylbenzenesulfonate, 2-aminoethane-1-sulfonic acid and <i<N</i<-(2-acetamido)-2-aminoethanesulfonic acid were used for modification of the representative of conducting polymers, polyaniline, and the resulting products were studied in the context of interactions with human blood. The anticoagulation activity was then correlated to surface energy and conductivity of the materials. Results show that anticoagulation activity is highly affected by the presence of suitable functional groups originating from the used heparin-like substances, and by the properties of polyaniline polymer itself.
abstract_unstemmed	<b< </b<Hemocompatibility is an essential prerequisite for the application of materials in the field of biomedicine and biosensing. In addition, mixed ionic and electronic conductivity of conducting polymers is an advantageous property for these applications. Heparin-like materials containing sulfate, sulfamic, and carboxylic groups may have an anticoagulation effect. Therefore, sodium dodecylbenzenesulfonate, 2-aminoethane-1-sulfonic acid and <i<N</i<-(2-acetamido)-2-aminoethanesulfonic acid were used for modification of the representative of conducting polymers, polyaniline, and the resulting products were studied in the context of interactions with human blood. The anticoagulation activity was then correlated to surface energy and conductivity of the materials. Results show that anticoagulation activity is highly affected by the presence of suitable functional groups originating from the used heparin-like substances, and by the properties of polyaniline polymer itself.
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title_short	In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules
url	https://doi.org/10.3390/polym11111861 https://doaj.org/article/d481bc54d1d14092ad4044fad1b2de10 https://www.mdpi.com/2073-4360/11/11/1861 https://doaj.org/toc/2073-4360
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up_date	2024-07-03T22:36:45.263Z
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In-Vitro Hemocompatibility of Polyaniline Functionalized by Bioactive Molecules

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