Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review

Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Vinciguerra L [verfasserIn] Cantone M [verfasserIn] Lanza G [verfasserIn] Bramanti A [verfasserIn] Santalucia P [verfasserIn] Puglisi V [verfasserIn] Pennisi G [verfasserIn] Bella R [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	biochemical change migrainous cerebral ischemia pathogenesis vasospasm

Übergeordnetes Werk:	In: Journal of Pain Research - Dove Medical Press, 2009, (2019), Seite 2941-2950
Übergeordnetes Werk:	year:2019 ; pages:2941-2950

Links:	Link aufrufen Link aufrufen Journal toc

Katalog-ID:	DOAJ05930099X

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ05930099X
003	DE-627
005	20230308232716.0
007	cr uuu---uuuuu
008	230228s2019 xx \|\|\|\|\|o 00\| \|\|eng c
035			\|a (DE-627)DOAJ05930099X
035			\|a (DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
050		0	\|a R5-920
100	0		\|a Vinciguerra L \|e verfasserin \|4 aut
245	1	0	\|a Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review
264		1	\|c 2019
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm
650		4	\|a biochemical change
650		4	\|a migrainous cerebral ischemia
650		4	\|a pathogenesis
650		4	\|a vasospasm
653		0	\|a Medicine (General)
700	0		\|a Cantone M \|e verfasserin \|4 aut
700	0		\|a Lanza G \|e verfasserin \|4 aut
700	0		\|a Bramanti A \|e verfasserin \|4 aut
700	0		\|a Santalucia P \|e verfasserin \|4 aut
700	0		\|a Puglisi V \|e verfasserin \|4 aut
700	0		\|a Pennisi G \|e verfasserin \|4 aut
700	0		\|a Bella R \|e verfasserin \|4 aut
773	0	8	\|i In \|t Journal of Pain Research \|d Dove Medical Press, 2009 \|g (2019), Seite 2941-2950 \|w (DE-627)600308383 \|w (DE-600)2495284-9 \|x 11787090 \|7 nnns
773	1	8	\|g year:2019 \|g pages:2941-2950
856	4	0	\|u https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9 \|z kostenfrei
856	4	0	\|u https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1178-7090 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_11
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|j 2019 \|h 2941-2950

Indexfelder

author_variant	v l vl c m cm l g lg b a ba s p sp p v pv p g pg b r br
matchkey_str	article:11787090:2019----::iriosnacinncrbavssamaeeot
hierarchy_sort_str	2019
callnumber-subject-code	R
publishDate	2019
allfields	(DE-627)DOAJ05930099X (DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9 DE-627 ger DE-627 rakwb eng R5-920 Vinciguerra L verfasserin aut Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm biochemical change migrainous cerebral ischemia pathogenesis vasospasm Medicine (General) Cantone M verfasserin aut Lanza G verfasserin aut Bramanti A verfasserin aut Santalucia P verfasserin aut Puglisi V verfasserin aut Pennisi G verfasserin aut Bella R verfasserin aut In Journal of Pain Research Dove Medical Press, 2009 (2019), Seite 2941-2950 (DE-627)600308383 (DE-600)2495284-9 11787090 nnns year:2019 pages:2941-2950 https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9 kostenfrei https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR kostenfrei https://doaj.org/toc/1178-7090 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019 2941-2950
spelling	(DE-627)DOAJ05930099X (DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9 DE-627 ger DE-627 rakwb eng R5-920 Vinciguerra L verfasserin aut Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm biochemical change migrainous cerebral ischemia pathogenesis vasospasm Medicine (General) Cantone M verfasserin aut Lanza G verfasserin aut Bramanti A verfasserin aut Santalucia P verfasserin aut Puglisi V verfasserin aut Pennisi G verfasserin aut Bella R verfasserin aut In Journal of Pain Research Dove Medical Press, 2009 (2019), Seite 2941-2950 (DE-627)600308383 (DE-600)2495284-9 11787090 nnns year:2019 pages:2941-2950 https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9 kostenfrei https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR kostenfrei https://doaj.org/toc/1178-7090 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019 2941-2950
allfields_unstemmed	(DE-627)DOAJ05930099X (DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9 DE-627 ger DE-627 rakwb eng R5-920 Vinciguerra L verfasserin aut Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm biochemical change migrainous cerebral ischemia pathogenesis vasospasm Medicine (General) Cantone M verfasserin aut Lanza G verfasserin aut Bramanti A verfasserin aut Santalucia P verfasserin aut Puglisi V verfasserin aut Pennisi G verfasserin aut Bella R verfasserin aut In Journal of Pain Research Dove Medical Press, 2009 (2019), Seite 2941-2950 (DE-627)600308383 (DE-600)2495284-9 11787090 nnns year:2019 pages:2941-2950 https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9 kostenfrei https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR kostenfrei https://doaj.org/toc/1178-7090 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019 2941-2950
allfieldsGer	(DE-627)DOAJ05930099X (DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9 DE-627 ger DE-627 rakwb eng R5-920 Vinciguerra L verfasserin aut Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm biochemical change migrainous cerebral ischemia pathogenesis vasospasm Medicine (General) Cantone M verfasserin aut Lanza G verfasserin aut Bramanti A verfasserin aut Santalucia P verfasserin aut Puglisi V verfasserin aut Pennisi G verfasserin aut Bella R verfasserin aut In Journal of Pain Research Dove Medical Press, 2009 (2019), Seite 2941-2950 (DE-627)600308383 (DE-600)2495284-9 11787090 nnns year:2019 pages:2941-2950 https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9 kostenfrei https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR kostenfrei https://doaj.org/toc/1178-7090 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019 2941-2950
allfieldsSound	(DE-627)DOAJ05930099X (DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9 DE-627 ger DE-627 rakwb eng R5-920 Vinciguerra L verfasserin aut Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm biochemical change migrainous cerebral ischemia pathogenesis vasospasm Medicine (General) Cantone M verfasserin aut Lanza G verfasserin aut Bramanti A verfasserin aut Santalucia P verfasserin aut Puglisi V verfasserin aut Pennisi G verfasserin aut Bella R verfasserin aut In Journal of Pain Research Dove Medical Press, 2009 (2019), Seite 2941-2950 (DE-627)600308383 (DE-600)2495284-9 11787090 nnns year:2019 pages:2941-2950 https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9 kostenfrei https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR kostenfrei https://doaj.org/toc/1178-7090 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2019 2941-2950
language	English
source	In Journal of Pain Research (2019), Seite 2941-2950 year:2019 pages:2941-2950
sourceStr	In Journal of Pain Research (2019), Seite 2941-2950 year:2019 pages:2941-2950
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	biochemical change migrainous cerebral ischemia pathogenesis vasospasm Medicine (General)
isfreeaccess_bool	true
container_title	Journal of Pain Research
authorswithroles_txt_mv	Vinciguerra L @@aut@@ Cantone M @@aut@@ Lanza G @@aut@@ Bramanti A @@aut@@ Santalucia P @@aut@@ Puglisi V @@aut@@ Pennisi G @@aut@@ Bella R @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
hierarchy_top_id	600308383
id	DOAJ05930099X
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ05930099X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230308232716.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2019 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ05930099X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">R5-920</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Vinciguerra L</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi &ldquo;Bonino Pulejo&rdquo;, Messina, Italy; 2Neurology Department, &ldquo;Sant&rsquo;Elia&rdquo; Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute &ndash; IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi &ldquo;Bonino Pulejo&rdquo;, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi &ldquo;Bonino Pulejo&rdquo;, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5&ndash;1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of &gamma;-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">biochemical change</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">migrainous cerebral ischemia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">pathogenesis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">vasospasm</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine (General)</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Cantone M</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Lanza G</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Bramanti A</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Santalucia P</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Puglisi V</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Pennisi G</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Bella R</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of Pain Research</subfield><subfield code="d">Dove Medical Press, 2009</subfield><subfield code="g">(2019), Seite 2941-2950</subfield><subfield code="w">(DE-627)600308383</subfield><subfield code="w">(DE-600)2495284-9</subfield><subfield code="x">11787090</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">year:2019</subfield><subfield code="g">pages:2941-2950</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1178-7090</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="j">2019</subfield><subfield code="h">2941-2950</subfield></datafield></record></collection>
callnumber-first	R - Medicine
author	Vinciguerra L
spellingShingle	Vinciguerra L misc R5-920 misc biochemical change misc migrainous cerebral ischemia misc pathogenesis misc vasospasm misc Medicine (General) Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review
authorStr	Vinciguerra L
ppnlink_with_tag_str_mv	@@773@@(DE-627)600308383
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	R5-920
illustrated	Not Illustrated
issn	11787090
topic_title	R5-920 Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review biochemical change migrainous cerebral ischemia pathogenesis vasospasm
topic	misc R5-920 misc biochemical change misc migrainous cerebral ischemia misc pathogenesis misc vasospasm misc Medicine (General)
topic_unstemmed	misc R5-920 misc biochemical change misc migrainous cerebral ischemia misc pathogenesis misc vasospasm misc Medicine (General)
topic_browse	misc R5-920 misc biochemical change misc migrainous cerebral ischemia misc pathogenesis misc vasospasm misc Medicine (General)
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Journal of Pain Research
hierarchy_parent_id	600308383
hierarchy_top_title	Journal of Pain Research
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)600308383 (DE-600)2495284-9
title	Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review
ctrlnum	(DE-627)DOAJ05930099X (DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9
title_full	Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review
author_sort	Vinciguerra L
journal	Journal of Pain Research
journalStr	Journal of Pain Research
callnumber-first-code	R
lang_code	eng
isOA_bool	true
recordtype	marc
publishDateSort	2019
contenttype_str_mv	txt
container_start_page	2941
author_browse	Vinciguerra L Cantone M Lanza G Bramanti A Santalucia P Puglisi V Pennisi G Bella R
class	R5-920
format_se	Elektronische Aufsätze
author-letter	Vinciguerra L
author2-role	verfasserin
title_sort	migrainous infarction and cerebral vasospasm: case report and literature review
callnumber	R5-920
title_auth	Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review
abstract	Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm
abstractGer	Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm
abstract_unstemmed	Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 2Neurology Department, “Sant’Elia” Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute – IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi “Bonino Pulejo”, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5–1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of γ-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
title_short	Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review
url	https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9 https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR https://doaj.org/toc/1178-7090
remote_bool	true
author2	Cantone M Lanza G Bramanti A Santalucia P Puglisi V Pennisi G Bella R
author2Str	Cantone M Lanza G Bramanti A Santalucia P Puglisi V Pennisi G Bella R
ppnlink	600308383
callnumber-subject	R - General Medicine
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
callnumber-a	R5-920
up_date	2024-07-03T22:48:30.007Z
_version_	1803599908716937216
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ05930099X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230308232716.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2019 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ05930099X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJc9840e04b28e4581a2ab65eec8aa38c9</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">R5-920</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Vinciguerra L</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Luisa Vinciguerra,1 Mariagiovanna Cantone,2 Giuseppe Lanza,3,4 Alessia Bramanti,5 Paola Santalucia,1 Valentina Puglisi,1 Giovanni Pennisi,3 Rita Bella6 1Neurology Department and Stroke Unit, IRCCS Centro Neurolesi &ldquo;Bonino Pulejo&rdquo;, Messina, Italy; 2Neurology Department, &ldquo;Sant&rsquo;Elia&rdquo; Hospital, Caltanissetta, Italy; 3Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy; 4Department of Neurology IC, Oasi Research Institute &ndash; IRCCS, Troina, Italy; 5Institute of Applied Sciences and Intelligent Systems (ISASI), IRCCS Centro Neurolesi &ldquo;Bonino Pulejo&rdquo;, Messina, Italy; 6Department of Medical and Surgical Sciences and Advanced Technology, Section of Neurosciences, University of Catania, Catania, ItalyCorrespondence: Luisa VinciguerraNeurology Department and Stroke Unit, IRCCS Centro Neurolesi &ldquo;Bonino Pulejo&rdquo;, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyTel +39 090 6012 8395Fax +39 090 6012 8850Email luisa.vinciguerrairccsme.itAbstract: Migrainous infarction (MI) is a rare complication of migraines that accounts for 0.5&ndash;1.5% of all ischemic strokes. Although the pathogenesis of MI is still debated, cortical spreading depression and the consequent biochemical cascade and hemodynamic changes are presumed to play an important role. Here we describe a case of MI and systematically review the literature on the complex and possibly bidirectional relationship between migraine and stroke. A 44-year-old female with history of migraine with visual aura presented at the Emergency Department due to a sudden onset of left limb paresis and hypoesthesia. Brain magnetic resonance imaging revealed right fronto-parietal ischemic stroke. Two days after hospitalization, the patient experienced a prolonged visual aura and showed ultrasound evidence of intracranial artery vasospasm. To date, there have been 33 published articles on a total 119 patients with MI, although intracranial vasospasm has rarely been reported. Sustained hyperexcitability of cortical neurons, impairment of &gamma;-aminobutyric acid inhibitory circuitry, altered serotonergic transmission, release of vasoconstrictive molecules, and cerebral blood flow changes have been proposed as pathogenic mechanisms of MI. The present case provides insight into the pathophysiological link between stroke and migraine, thus aiding clinicians in therapeutic decision-making although additional studies are needed to clarify the clinical, neuroradiological, and ultrasound findings that link MI and stroke-related migraine.Keywords: biochemical change, migrainous cerebral ischemia, pathogenesis, vasospasm</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">biochemical change</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">migrainous cerebral ischemia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">pathogenesis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">vasospasm</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine (General)</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Cantone M</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Lanza G</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Bramanti A</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Santalucia P</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Puglisi V</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Pennisi G</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Bella R</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of Pain Research</subfield><subfield code="d">Dove Medical Press, 2009</subfield><subfield code="g">(2019), Seite 2941-2950</subfield><subfield code="w">(DE-627)600308383</subfield><subfield code="w">(DE-600)2495284-9</subfield><subfield code="x">11787090</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">year:2019</subfield><subfield code="g">pages:2941-2950</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/c9840e04b28e4581a2ab65eec8aa38c9</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.dovepress.com/migrainous-infarction-and-cerebral-vasospasm-case-report-and-literatur-peer-reviewed-article-JPR</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1178-7090</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="j">2019</subfield><subfield code="h">2941-2950</subfield></datafield></record></collection>
score	7.397317

Nicht das Richtige dabei?

Schreiben Sie uns!

Migrainous Infarction And Cerebral Vasospasm: Case Report And Literature Review

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?