Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test

Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and...
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Autor*in:	R N Suresha [verfasserIn] Siddamma Amoghimath [verfasserIn] M K Jayanthi [verfasserIn] S L Shruthi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	Bethanechol capillary blood glucose (CBG) diabetes euglycemic oral glucose tolerance test (OGTT)

Übergeordnetes Werk:	In: Muller Journal of Medical Sciences and Research - Wolters Kluwer Medknow Publications, 2019, 7(2016), 2, Seite 115-120
Übergeordnetes Werk:	volume:7 ; year:2016 ; number:2 ; pages:115-120

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.4103/0975-9727.185011

Katalog-ID:	DOAJ059440066

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520			\|a Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT.
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allfields	10.4103/0975-9727.185011 doi (DE-627)DOAJ059440066 (DE-599)DOAJbccb1f0a7b824ab3a2ef80eb950b80e4 DE-627 ger DE-627 rakwb eng RT1-120 RX1-681 R N Suresha verfasserin aut Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT. Bethanechol capillary blood glucose (CBG) diabetes euglycemic oral glucose tolerance test (OGTT) Nursing Homeopathy Siddamma Amoghimath verfasserin aut M K Jayanthi verfasserin aut S L Shruthi verfasserin aut In Muller Journal of Medical Sciences and Research Wolters Kluwer Medknow Publications, 2019 7(2016), 2, Seite 115-120 (DE-627)770027792 (DE-600)2736465-3 23213701 nnns volume:7 year:2016 number:2 pages:115-120 https://doi.org/10.4103/0975-9727.185011 kostenfrei https://doaj.org/article/bccb1f0a7b824ab3a2ef80eb950b80e4 kostenfrei http://www.mjmsr.net/article.asp?issn=0975-9727;year=2016;volume=7;issue=2;spage=115;epage=120;aulast= kostenfrei https://doaj.org/toc/0975-9727 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2016 2 115-120
spelling	10.4103/0975-9727.185011 doi (DE-627)DOAJ059440066 (DE-599)DOAJbccb1f0a7b824ab3a2ef80eb950b80e4 DE-627 ger DE-627 rakwb eng RT1-120 RX1-681 R N Suresha verfasserin aut Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT. Bethanechol capillary blood glucose (CBG) diabetes euglycemic oral glucose tolerance test (OGTT) Nursing Homeopathy Siddamma Amoghimath verfasserin aut M K Jayanthi verfasserin aut S L Shruthi verfasserin aut In Muller Journal of Medical Sciences and Research Wolters Kluwer Medknow Publications, 2019 7(2016), 2, Seite 115-120 (DE-627)770027792 (DE-600)2736465-3 23213701 nnns volume:7 year:2016 number:2 pages:115-120 https://doi.org/10.4103/0975-9727.185011 kostenfrei https://doaj.org/article/bccb1f0a7b824ab3a2ef80eb950b80e4 kostenfrei http://www.mjmsr.net/article.asp?issn=0975-9727;year=2016;volume=7;issue=2;spage=115;epage=120;aulast= kostenfrei https://doaj.org/toc/0975-9727 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2016 2 115-120
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allfieldsGer	10.4103/0975-9727.185011 doi (DE-627)DOAJ059440066 (DE-599)DOAJbccb1f0a7b824ab3a2ef80eb950b80e4 DE-627 ger DE-627 rakwb eng RT1-120 RX1-681 R N Suresha verfasserin aut Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT. Bethanechol capillary blood glucose (CBG) diabetes euglycemic oral glucose tolerance test (OGTT) Nursing Homeopathy Siddamma Amoghimath verfasserin aut M K Jayanthi verfasserin aut S L Shruthi verfasserin aut In Muller Journal of Medical Sciences and Research Wolters Kluwer Medknow Publications, 2019 7(2016), 2, Seite 115-120 (DE-627)770027792 (DE-600)2736465-3 23213701 nnns volume:7 year:2016 number:2 pages:115-120 https://doi.org/10.4103/0975-9727.185011 kostenfrei https://doaj.org/article/bccb1f0a7b824ab3a2ef80eb950b80e4 kostenfrei http://www.mjmsr.net/article.asp?issn=0975-9727;year=2016;volume=7;issue=2;spage=115;epage=120;aulast= kostenfrei https://doaj.org/toc/0975-9727 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2016 2 115-120
allfieldsSound	10.4103/0975-9727.185011 doi (DE-627)DOAJ059440066 (DE-599)DOAJbccb1f0a7b824ab3a2ef80eb950b80e4 DE-627 ger DE-627 rakwb eng RT1-120 RX1-681 R N Suresha verfasserin aut Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT. Bethanechol capillary blood glucose (CBG) diabetes euglycemic oral glucose tolerance test (OGTT) Nursing Homeopathy Siddamma Amoghimath verfasserin aut M K Jayanthi verfasserin aut S L Shruthi verfasserin aut In Muller Journal of Medical Sciences and Research Wolters Kluwer Medknow Publications, 2019 7(2016), 2, Seite 115-120 (DE-627)770027792 (DE-600)2736465-3 23213701 nnns volume:7 year:2016 number:2 pages:115-120 https://doi.org/10.4103/0975-9727.185011 kostenfrei https://doaj.org/article/bccb1f0a7b824ab3a2ef80eb950b80e4 kostenfrei http://www.mjmsr.net/article.asp?issn=0975-9727;year=2016;volume=7;issue=2;spage=115;epage=120;aulast= kostenfrei https://doaj.org/toc/0975-9727 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2016 2 115-120
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Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. 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callnumber-first	R - Medicine
author	R N Suresha
spellingShingle	R N Suresha misc RT1-120 misc RX1-681 misc Bethanechol misc capillary blood glucose (CBG) misc diabetes misc euglycemic misc oral glucose tolerance test (OGTT) misc Nursing misc Homeopathy Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test
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topic_title	RT1-120 RX1-681 Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test Bethanechol capillary blood glucose (CBG) diabetes euglycemic oral glucose tolerance test (OGTT)
topic	misc RT1-120 misc RX1-681 misc Bethanechol misc capillary blood glucose (CBG) misc diabetes misc euglycemic misc oral glucose tolerance test (OGTT) misc Nursing misc Homeopathy
topic_unstemmed	misc RT1-120 misc RX1-681 misc Bethanechol misc capillary blood glucose (CBG) misc diabetes misc euglycemic misc oral glucose tolerance test (OGTT) misc Nursing misc Homeopathy
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title	Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test
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title_full	Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test
author_sort	R N Suresha
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author_browse	R N Suresha Siddamma Amoghimath M K Jayanthi S L Shruthi
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title_sort	evaluate the effect of bethanechol on blood glucose levels in euglycemic wistar albino rats through oral glucose tolerance test
callnumber	RT1-120
title_auth	Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test
abstract	Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT.
abstractGer	Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT.
abstract_unstemmed	Objective: To evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test (OGTT). Materials and Methods: Twelve Wistar albino rats weighing around 150-200 g of either sex were randomly selected from the central animal facility, and were divided into two groups. The control group received distilled water (25 mL/kg body wt.) per orally, test groups received bethanechol (3.6 mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 h after drug administration in all the groups of rats OGTT was performed, by administering oral glucose in dose of 0.6 gm/kg body weight. The capillary blood glucose (CBG) levels were measured at 0 min, 60 min, and 150 min, by rat tail snipping method using glucometer (ACCUCHEK). Results: The CBG levels of the bethanechol group was less when compared to the control group at all time intervals and the difference was statistically significant. Conclusion: Bethanechol showed the hypoglycemic activity when given for 5 days orally to euglycemic albino rats through OGTT.
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title_short	Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test
url	https://doi.org/10.4103/0975-9727.185011 https://doaj.org/article/bccb1f0a7b824ab3a2ef80eb950b80e4 http://www.mjmsr.net/article.asp?issn=0975-9727;year=2016;volume=7;issue=2;spage=115;epage=120;aulast= https://doaj.org/toc/0975-9727
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author2	Siddamma Amoghimath M K Jayanthi S L Shruthi
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up_date	2024-07-03T23:28:59.422Z
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Evaluate the effect of bethanechol on blood glucose levels in euglycemic Wistar albino rats through oral glucose tolerance test

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