DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C

Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medici...
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Autor*in:	Hidayat Ullah [verfasserIn] Ateeq Ur Rehman [verfasserIn] Huma Aslam [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	splenic artery pulsatility index hepatitis c infection

Übergeordnetes Werk:	In: Pakistan Armed Forces Medical Journal - Army Medical College Rawalpindi, 2016, 68(2018), 6, Seite 1630-1635
Übergeordnetes Werk:	volume:68 ; year:2018 ; number:6 ; pages:1630-1635

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ059899964

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520			\|a Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies.
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allfields	(DE-627)DOAJ059899964 (DE-599)DOAJ2a11aaf0754f488ab2c7a022951ef865 DE-627 ger DE-627 rakwb eng R5-920 Hidayat Ullah verfasserin aut DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies. splenic artery pulsatility index hepatitis c infection Medicine R Medicine (General) Ateeq Ur Rehman verfasserin aut Huma Aslam verfasserin aut In Pakistan Armed Forces Medical Journal Army Medical College Rawalpindi, 2016 68(2018), 6, Seite 1630-1635 (DE-627)1016057962 24118842 nnns volume:68 year:2018 number:6 pages:1630-1635 https://doaj.org/article/2a11aaf0754f488ab2c7a022951ef865 kostenfrei https://www.pafmj.org/index.php/PAFMJ/article/view/2561/2099 kostenfrei https://doaj.org/toc/0030-9648 Journal toc kostenfrei https://doaj.org/toc/2411-8842 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 68 2018 6 1630-1635
spelling	(DE-627)DOAJ059899964 (DE-599)DOAJ2a11aaf0754f488ab2c7a022951ef865 DE-627 ger DE-627 rakwb eng R5-920 Hidayat Ullah verfasserin aut DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies. splenic artery pulsatility index hepatitis c infection Medicine R Medicine (General) Ateeq Ur Rehman verfasserin aut Huma Aslam verfasserin aut In Pakistan Armed Forces Medical Journal Army Medical College Rawalpindi, 2016 68(2018), 6, Seite 1630-1635 (DE-627)1016057962 24118842 nnns volume:68 year:2018 number:6 pages:1630-1635 https://doaj.org/article/2a11aaf0754f488ab2c7a022951ef865 kostenfrei https://www.pafmj.org/index.php/PAFMJ/article/view/2561/2099 kostenfrei https://doaj.org/toc/0030-9648 Journal toc kostenfrei https://doaj.org/toc/2411-8842 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 68 2018 6 1630-1635
allfields_unstemmed	(DE-627)DOAJ059899964 (DE-599)DOAJ2a11aaf0754f488ab2c7a022951ef865 DE-627 ger DE-627 rakwb eng R5-920 Hidayat Ullah verfasserin aut DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies. splenic artery pulsatility index hepatitis c infection Medicine R Medicine (General) Ateeq Ur Rehman verfasserin aut Huma Aslam verfasserin aut In Pakistan Armed Forces Medical Journal Army Medical College Rawalpindi, 2016 68(2018), 6, Seite 1630-1635 (DE-627)1016057962 24118842 nnns volume:68 year:2018 number:6 pages:1630-1635 https://doaj.org/article/2a11aaf0754f488ab2c7a022951ef865 kostenfrei https://www.pafmj.org/index.php/PAFMJ/article/view/2561/2099 kostenfrei https://doaj.org/toc/0030-9648 Journal toc kostenfrei https://doaj.org/toc/2411-8842 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 68 2018 6 1630-1635
allfieldsGer	(DE-627)DOAJ059899964 (DE-599)DOAJ2a11aaf0754f488ab2c7a022951ef865 DE-627 ger DE-627 rakwb eng R5-920 Hidayat Ullah verfasserin aut DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies. splenic artery pulsatility index hepatitis c infection Medicine R Medicine (General) Ateeq Ur Rehman verfasserin aut Huma Aslam verfasserin aut In Pakistan Armed Forces Medical Journal Army Medical College Rawalpindi, 2016 68(2018), 6, Seite 1630-1635 (DE-627)1016057962 24118842 nnns volume:68 year:2018 number:6 pages:1630-1635 https://doaj.org/article/2a11aaf0754f488ab2c7a022951ef865 kostenfrei https://www.pafmj.org/index.php/PAFMJ/article/view/2561/2099 kostenfrei https://doaj.org/toc/0030-9648 Journal toc kostenfrei https://doaj.org/toc/2411-8842 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 68 2018 6 1630-1635
allfieldsSound	(DE-627)DOAJ059899964 (DE-599)DOAJ2a11aaf0754f488ab2c7a022951ef865 DE-627 ger DE-627 rakwb eng R5-920 Hidayat Ullah verfasserin aut DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies. splenic artery pulsatility index hepatitis c infection Medicine R Medicine (General) Ateeq Ur Rehman verfasserin aut Huma Aslam verfasserin aut In Pakistan Armed Forces Medical Journal Army Medical College Rawalpindi, 2016 68(2018), 6, Seite 1630-1635 (DE-627)1016057962 24118842 nnns volume:68 year:2018 number:6 pages:1630-1635 https://doaj.org/article/2a11aaf0754f488ab2c7a022951ef865 kostenfrei https://www.pafmj.org/index.php/PAFMJ/article/view/2561/2099 kostenfrei https://doaj.org/toc/0030-9648 Journal toc kostenfrei https://doaj.org/toc/2411-8842 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 68 2018 6 1630-1635
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source	In Pakistan Armed Forces Medical Journal 68(2018), 6, Seite 1630-1635 volume:68 year:2018 number:6 pages:1630-1635
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callnumber-first	R - Medicine
author	Hidayat Ullah
spellingShingle	Hidayat Ullah misc R5-920 misc splenic artery pulsatility index misc hepatitis c infection misc Medicine misc R misc Medicine (General) DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C
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topic_title	R5-920 DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C splenic artery pulsatility index hepatitis c infection
topic	misc R5-920 misc splenic artery pulsatility index misc hepatitis c infection misc Medicine misc R misc Medicine (General)
topic_unstemmed	misc R5-920 misc splenic artery pulsatility index misc hepatitis c infection misc Medicine misc R misc Medicine (General)
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title	DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C
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title_full	DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C
author_sort	Hidayat Ullah
journal	Pakistan Armed Forces Medical Journal
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author-letter	Hidayat Ullah
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title_sort	diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis c
callnumber	R5-920
title_auth	DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C
abstract	Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies.
abstractGer	Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies.
abstract_unstemmed	Objective: To find the diagnostic accuracy of splenic artery pulsatility index in predicting fibrosis associated with chronic hepatitis C. Study Design: Cross-sectional validation study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, Departments of Medicine and Pathology, Pak Emirates Military Hospital Rawalpindi, from Sep 2014 to Feb 2015. Material and Methods: Seventy-five patients with evidence of HCV infection as detected by positive anti HCV antibodies and HCV RNA for more than 6 months were recruited in this study using consecutive sampling. Ultrasound evaluation of liver and spleen was carried out after overnight fast along with doppler evaluation of splenic artery. Histopathological findings, of the subsequently done liver biopsy, were recorded as gold standard. Findings were recorded on the already prepared proforma. Statistical package for social sciences version 20 was used for the analysis of the data. Results: The average age of the patients was 36.87 ± 8.16 years. Sensitivity, specificity, Positive predictive value, negative predictive value and diagnostic accuracy of increased splenic artery pulsatility index in assessing the severity of hepatic fibrosis were 80.8%, 91.8%, 84%, 90% and 88% respectively. ROC curve showed area under the curve to be 0.917 with p<0.001. Conclusion: Splenic artery pulsatility index is a simple, non-invasive and reproducible technique for assessing hepatic fibrosis in patients with chronic hepatitis C and can reduce the number of staging liver biopsies.
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title_short	DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C
url	https://doaj.org/article/2a11aaf0754f488ab2c7a022951ef865 https://www.pafmj.org/index.php/PAFMJ/article/view/2561/2099 https://doaj.org/toc/0030-9648 https://doaj.org/toc/2411-8842
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up_date	2024-07-04T01:20:19.314Z
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DIAGNOSTIC ACCURACY OF SPLENIC ARTERY PULSATILITY INDEX IN PREDICTING FIBROSIS ASSOCIATED WITH CHRONIC HEPATITIS C

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