Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages

Adipose tissue macrophages are central to controlling inflammation in the context of obesity. Here the authors present a new infrared dye (IR-61) that accumulates in the mitochondria of these cells resulting in anti-inflammatory effects that counter obesity-associated pathology in mice.

Gespeichert in:

Autor*in:	Yawei Wang [verfasserIn] Binlin Tang [verfasserIn] Lei Long [verfasserIn] Peng Luo [verfasserIn] Wei Xiang [verfasserIn] Xueru Li [verfasserIn] Huilan Wang [verfasserIn] Qingzhi Jiang [verfasserIn] Xu Tan [verfasserIn] Shenglin Luo [verfasserIn] Huijuan Li [verfasserIn] Ziwen Wang [verfasserIn] Zelin Chen [verfasserIn] Yu Leng [verfasserIn] Zhongyong Jiang [verfasserIn] Yang Wang [verfasserIn] Le Ma [verfasserIn] Rui Wang [verfasserIn] Chunyu Zeng [verfasserIn] Zujuan Liu [verfasserIn] Yu Wang [verfasserIn] Hongming Miao [verfasserIn] Chunmeng Shi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 12(2021), 1, Seite 16
Übergeordnetes Werk:	volume:12 ; year:2021 ; number:1 ; pages:16

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-020-20315-9

Katalog-ID:	DOAJ06003193X

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source	In Nature Communications 12(2021), 1, Seite 16 volume:12 year:2021 number:1 pages:16
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author	Yawei Wang
spellingShingle	Yawei Wang misc Science misc Q Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
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topic_title	Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
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title	Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
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title_full	Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
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author_browse	Yawei Wang Binlin Tang Lei Long Peng Luo Wei Xiang Xueru Li Huilan Wang Qingzhi Jiang Xu Tan Shenglin Luo Huijuan Li Ziwen Wang Zelin Chen Yu Leng Zhongyong Jiang Yang Wang Le Ma Rui Wang Chunyu Zeng Zujuan Liu Yu Wang Hongming Miao Chunmeng Shi
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title_sort	improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
title_auth	Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
abstract	Adipose tissue macrophages are central to controlling inflammation in the context of obesity. Here the authors present a new infrared dye (IR-61) that accumulates in the mitochondria of these cells resulting in anti-inflammatory effects that counter obesity-associated pathology in mice.
abstractGer	Adipose tissue macrophages are central to controlling inflammation in the context of obesity. Here the authors present a new infrared dye (IR-61) that accumulates in the mitochondria of these cells resulting in anti-inflammatory effects that counter obesity-associated pathology in mice.
abstract_unstemmed	Adipose tissue macrophages are central to controlling inflammation in the context of obesity. Here the authors present a new infrared dye (IR-61) that accumulates in the mitochondria of these cells resulting in anti-inflammatory effects that counter obesity-associated pathology in mice.
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title_short	Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
url	https://doi.org/10.1038/s41467-020-20315-9 https://doaj.org/article/6984acd91fab463ba6643d7cdc1514c5 https://doaj.org/toc/2041-1723
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author2	Binlin Tang Lei Long Peng Luo Wei Xiang Xueru Li Huilan Wang Qingzhi Jiang Xu Tan Shenglin Luo Huijuan Li Ziwen Wang Zelin Chen Yu Leng Zhongyong Jiang Yang Wang Le Ma Rui Wang Chunyu Zeng Zujuan Liu Yu Wang Hongming Miao Chunmeng Shi
author2Str	Binlin Tang Lei Long Peng Luo Wei Xiang Xueru Li Huilan Wang Qingzhi Jiang Xu Tan Shenglin Luo Huijuan Li Ziwen Wang Zelin Chen Yu Leng Zhongyong Jiang Yang Wang Le Ma Rui Wang Chunyu Zeng Zujuan Liu Yu Wang Hongming Miao Chunmeng Shi
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up_date	2024-07-04T01:48:02.576Z
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