Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein

ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disea...
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Autor*in:	Zhiwen Wang [verfasserIn] Yuxin Chen [verfasserIn] Xinhui Zhou [verfasserIn] Changfeng Wang [verfasserIn] Xianjun Chen [verfasserIn] Feixiang Min [verfasserIn] Ruen Liu [verfasserIn] Hui Xiang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries

Übergeordnetes Werk:	In: Frontiers in Surgery - Frontiers Media S.A., 2014, 9(2022)
Übergeordnetes Werk:	volume:9 ; year:2022

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fsurg.2022.692383

Katalog-ID:	DOAJ060131802

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520			\|a ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group.
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allfields	10.3389/fsurg.2022.692383 doi (DE-627)DOAJ060131802 (DE-599)DOAJe45eeb03c21947c78f7f8b02a3a65f9f DE-627 ger DE-627 rakwb eng RD1-811 Zhiwen Wang verfasserin aut Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group. cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries Surgery Yuxin Chen verfasserin aut Xinhui Zhou verfasserin aut Changfeng Wang verfasserin aut Xianjun Chen verfasserin aut Feixiang Min verfasserin aut Ruen Liu verfasserin aut Ruen Liu verfasserin aut Hui Xiang verfasserin aut In Frontiers in Surgery Frontiers Media S.A., 2014 9(2022) (DE-627)788288954 (DE-600)2773823-1 2296875X nnns volume:9 year:2022 https://doi.org/10.3389/fsurg.2022.692383 kostenfrei https://doaj.org/article/e45eeb03c21947c78f7f8b02a3a65f9f kostenfrei https://www.frontiersin.org/articles/10.3389/fsurg.2022.692383/full kostenfrei https://doaj.org/toc/2296-875X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_2446 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022
spelling	10.3389/fsurg.2022.692383 doi (DE-627)DOAJ060131802 (DE-599)DOAJe45eeb03c21947c78f7f8b02a3a65f9f DE-627 ger DE-627 rakwb eng RD1-811 Zhiwen Wang verfasserin aut Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group. cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries Surgery Yuxin Chen verfasserin aut Xinhui Zhou verfasserin aut Changfeng Wang verfasserin aut Xianjun Chen verfasserin aut Feixiang Min verfasserin aut Ruen Liu verfasserin aut Ruen Liu verfasserin aut Hui Xiang verfasserin aut In Frontiers in Surgery Frontiers Media S.A., 2014 9(2022) (DE-627)788288954 (DE-600)2773823-1 2296875X nnns volume:9 year:2022 https://doi.org/10.3389/fsurg.2022.692383 kostenfrei https://doaj.org/article/e45eeb03c21947c78f7f8b02a3a65f9f kostenfrei https://www.frontiersin.org/articles/10.3389/fsurg.2022.692383/full kostenfrei https://doaj.org/toc/2296-875X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_2446 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022
allfields_unstemmed	10.3389/fsurg.2022.692383 doi (DE-627)DOAJ060131802 (DE-599)DOAJe45eeb03c21947c78f7f8b02a3a65f9f DE-627 ger DE-627 rakwb eng RD1-811 Zhiwen Wang verfasserin aut Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group. cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries Surgery Yuxin Chen verfasserin aut Xinhui Zhou verfasserin aut Changfeng Wang verfasserin aut Xianjun Chen verfasserin aut Feixiang Min verfasserin aut Ruen Liu verfasserin aut Ruen Liu verfasserin aut Hui Xiang verfasserin aut In Frontiers in Surgery Frontiers Media S.A., 2014 9(2022) (DE-627)788288954 (DE-600)2773823-1 2296875X nnns volume:9 year:2022 https://doi.org/10.3389/fsurg.2022.692383 kostenfrei https://doaj.org/article/e45eeb03c21947c78f7f8b02a3a65f9f kostenfrei https://www.frontiersin.org/articles/10.3389/fsurg.2022.692383/full kostenfrei https://doaj.org/toc/2296-875X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_2446 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022
allfieldsGer	10.3389/fsurg.2022.692383 doi (DE-627)DOAJ060131802 (DE-599)DOAJe45eeb03c21947c78f7f8b02a3a65f9f DE-627 ger DE-627 rakwb eng RD1-811 Zhiwen Wang verfasserin aut Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group. cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries Surgery Yuxin Chen verfasserin aut Xinhui Zhou verfasserin aut Changfeng Wang verfasserin aut Xianjun Chen verfasserin aut Feixiang Min verfasserin aut Ruen Liu verfasserin aut Ruen Liu verfasserin aut Hui Xiang verfasserin aut In Frontiers in Surgery Frontiers Media S.A., 2014 9(2022) (DE-627)788288954 (DE-600)2773823-1 2296875X nnns volume:9 year:2022 https://doi.org/10.3389/fsurg.2022.692383 kostenfrei https://doaj.org/article/e45eeb03c21947c78f7f8b02a3a65f9f kostenfrei https://www.frontiersin.org/articles/10.3389/fsurg.2022.692383/full kostenfrei https://doaj.org/toc/2296-875X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_2446 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022
allfieldsSound	10.3389/fsurg.2022.692383 doi (DE-627)DOAJ060131802 (DE-599)DOAJe45eeb03c21947c78f7f8b02a3a65f9f DE-627 ger DE-627 rakwb eng RD1-811 Zhiwen Wang verfasserin aut Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group. cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries Surgery Yuxin Chen verfasserin aut Xinhui Zhou verfasserin aut Changfeng Wang verfasserin aut Xianjun Chen verfasserin aut Feixiang Min verfasserin aut Ruen Liu verfasserin aut Ruen Liu verfasserin aut Hui Xiang verfasserin aut In Frontiers in Surgery Frontiers Media S.A., 2014 9(2022) (DE-627)788288954 (DE-600)2773823-1 2296875X nnns volume:9 year:2022 https://doi.org/10.3389/fsurg.2022.692383 kostenfrei https://doaj.org/article/e45eeb03c21947c78f7f8b02a3a65f9f kostenfrei https://www.frontiersin.org/articles/10.3389/fsurg.2022.692383/full kostenfrei https://doaj.org/toc/2296-875X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_2446 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022
language	English
source	In Frontiers in Surgery 9(2022) volume:9 year:2022
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topic_facet	cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries Surgery
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authorswithroles_txt_mv	Zhiwen Wang @@aut@@ Yuxin Chen @@aut@@ Xinhui Zhou @@aut@@ Changfeng Wang @@aut@@ Xianjun Chen @@aut@@ Feixiang Min @@aut@@ Ruen Liu @@aut@@ Hui Xiang @@aut@@
publishDateDaySort_date	2022-01-01T00:00:00Z
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CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score &lt;8 were independent risk factors for PHH. 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callnumber-first	R - Medicine
author	Zhiwen Wang
spellingShingle	Zhiwen Wang misc RD1-811 misc cerebrospinal fluid total protein misc GCS misc intraventricular hemorrhage misc intracerebral hemorrhage misc subarachnoid space hemorrhage misc traumatic brain injuries misc Surgery Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein
authorStr	Zhiwen Wang
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topic_title	RD1-811 Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein cerebrospinal fluid total protein GCS intraventricular hemorrhage intracerebral hemorrhage subarachnoid space hemorrhage traumatic brain injuries
topic	misc RD1-811 misc cerebrospinal fluid total protein misc GCS misc intraventricular hemorrhage misc intracerebral hemorrhage misc subarachnoid space hemorrhage misc traumatic brain injuries misc Surgery
topic_unstemmed	misc RD1-811 misc cerebrospinal fluid total protein misc GCS misc intraventricular hemorrhage misc intracerebral hemorrhage misc subarachnoid space hemorrhage misc traumatic brain injuries misc Surgery
topic_browse	misc RD1-811 misc cerebrospinal fluid total protein misc GCS misc intraventricular hemorrhage misc intracerebral hemorrhage misc subarachnoid space hemorrhage misc traumatic brain injuries misc Surgery
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
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title	Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein
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title_full	Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein
author_sort	Zhiwen Wang
journal	Frontiers in Surgery
journalStr	Frontiers in Surgery
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lang_code	eng
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author_browse	Zhiwen Wang Yuxin Chen Xinhui Zhou Changfeng Wang Xianjun Chen Feixiang Min Ruen Liu Hui Xiang
container_volume	9
class	RD1-811
format_se	Elektronische Aufsätze
author-letter	Zhiwen Wang
doi_str_mv	10.3389/fsurg.2022.692383
author2-role	verfasserin
title_sort	risk factor of posthemorrhagic hydrocephalus: cerebrospinal fluid total protein
callnumber	RD1-811
title_auth	Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein
abstract	ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group.
abstractGer	ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group.
abstract_unstemmed	ObjectiveCerebrospinal fluid total protein (CSF-TP) levels in adults with posthemorrhagic hydrocephalus (PHH) are poorly studied. The objective of this study was to explore the characteristics of CSF-TP levels in patients with PHH.MethodsThe clinical data of 156 patients with hemorrhagic brain disease were retrospectively studied and divided into PHH and NPHH groups. Single-factor and multi-factor analyses were performed, and the key role of CSF-TP was evaluated using linear analysis.ResultsAmong the 156 patients, 85 (54.5%) had PHH and 34 (21.8%) underwent surgeries. Hypertension (p = 0.017), days [total fever time when body temperature ≥ 38.5°C (p = 0.04)], Glasgow Coma Scale (GCS) score (p < 0.001), and time (from the onset of the disease to the obtainment of CSF-TP after lumbar puncture (p < 0.001) were important factors for PHH. Logistic regression analysis revealed that GCS score < 8 [odds ratio (OR) = 2.943 (1.421–6.097), p = 0.004] and CSF-TP × time ≥ 9,600 [OR = 2.317 (1.108–4.849), p = 0.026] were independent risk factors for PHH. All CSF-TP values were averaged every 2 days. CSF-TP was negatively correlated with time. Linear analysis showed that CSF-TP in the PHH group was higher than that in the NPHH group at the same onset time, and that the duration of detectionin the CSF was longer.ConclusionCerebrospinal fluid total protein (CSF-TP) × time ≥ 9,600 and GCS score <8 were independent risk factors for PHH. CSF-TP was higher in the PHH group than in the NPHH group.
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title_short	Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein
url	https://doi.org/10.3389/fsurg.2022.692383 https://doaj.org/article/e45eeb03c21947c78f7f8b02a3a65f9f https://www.frontiersin.org/articles/10.3389/fsurg.2022.692383/full https://doaj.org/toc/2296-875X
remote_bool	true
author2	Yuxin Chen Xinhui Zhou Changfeng Wang Xianjun Chen Feixiang Min Ruen Liu Hui Xiang
author2Str	Yuxin Chen Xinhui Zhou Changfeng Wang Xianjun Chen Feixiang Min Ruen Liu Hui Xiang
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up_date	2024-07-04T02:07:46.931Z
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