T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rat...
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Autor*in:	Olutayo A. Sogunro [verfasserIn] Rachael Steinhauer [verfasserIn] Eugene Lewis [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy

Übergeordnetes Werk:	In: Current Problems in Cancer: Case Reports - Elsevier, 2021, 2(2020), Seite 100041-
Übergeordnetes Werk:	volume:2 ; year:2020 ; pages:100041-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.cpccr.2020.100041

Katalog-ID:	DOAJ060330031

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allfields	10.1016/j.cpccr.2020.100041 doi (DE-627)DOAJ060330031 (DE-599)DOAJ9759c0746d8345adae0cfbeeeae1dba3 DE-627 ger DE-627 rakwb eng RC254-282 Olutayo A. Sogunro verfasserin aut T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma. T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Rachael Steinhauer verfasserin aut Eugene Lewis verfasserin aut In Current Problems in Cancer: Case Reports Elsevier, 2021 2(2020), Seite 100041- (DE-627)1698858809 26666219 nnns volume:2 year:2020 pages:100041- https://doi.org/10.1016/j.cpccr.2020.100041 kostenfrei https://doaj.org/article/9759c0746d8345adae0cfbeeeae1dba3 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666621920300417 kostenfrei https://doaj.org/toc/2666-6219 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2020 100041-
spelling	10.1016/j.cpccr.2020.100041 doi (DE-627)DOAJ060330031 (DE-599)DOAJ9759c0746d8345adae0cfbeeeae1dba3 DE-627 ger DE-627 rakwb eng RC254-282 Olutayo A. Sogunro verfasserin aut T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma. T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Rachael Steinhauer verfasserin aut Eugene Lewis verfasserin aut In Current Problems in Cancer: Case Reports Elsevier, 2021 2(2020), Seite 100041- (DE-627)1698858809 26666219 nnns volume:2 year:2020 pages:100041- https://doi.org/10.1016/j.cpccr.2020.100041 kostenfrei https://doaj.org/article/9759c0746d8345adae0cfbeeeae1dba3 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666621920300417 kostenfrei https://doaj.org/toc/2666-6219 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2020 100041-
allfields_unstemmed	10.1016/j.cpccr.2020.100041 doi (DE-627)DOAJ060330031 (DE-599)DOAJ9759c0746d8345adae0cfbeeeae1dba3 DE-627 ger DE-627 rakwb eng RC254-282 Olutayo A. Sogunro verfasserin aut T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma. T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Rachael Steinhauer verfasserin aut Eugene Lewis verfasserin aut In Current Problems in Cancer: Case Reports Elsevier, 2021 2(2020), Seite 100041- (DE-627)1698858809 26666219 nnns volume:2 year:2020 pages:100041- https://doi.org/10.1016/j.cpccr.2020.100041 kostenfrei https://doaj.org/article/9759c0746d8345adae0cfbeeeae1dba3 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666621920300417 kostenfrei https://doaj.org/toc/2666-6219 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2020 100041-
allfieldsGer	10.1016/j.cpccr.2020.100041 doi (DE-627)DOAJ060330031 (DE-599)DOAJ9759c0746d8345adae0cfbeeeae1dba3 DE-627 ger DE-627 rakwb eng RC254-282 Olutayo A. Sogunro verfasserin aut T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma. T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Rachael Steinhauer verfasserin aut Eugene Lewis verfasserin aut In Current Problems in Cancer: Case Reports Elsevier, 2021 2(2020), Seite 100041- (DE-627)1698858809 26666219 nnns volume:2 year:2020 pages:100041- https://doi.org/10.1016/j.cpccr.2020.100041 kostenfrei https://doaj.org/article/9759c0746d8345adae0cfbeeeae1dba3 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666621920300417 kostenfrei https://doaj.org/toc/2666-6219 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2020 100041-
allfieldsSound	10.1016/j.cpccr.2020.100041 doi (DE-627)DOAJ060330031 (DE-599)DOAJ9759c0746d8345adae0cfbeeeae1dba3 DE-627 ger DE-627 rakwb eng RC254-282 Olutayo A. Sogunro verfasserin aut T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma. T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Rachael Steinhauer verfasserin aut Eugene Lewis verfasserin aut In Current Problems in Cancer: Case Reports Elsevier, 2021 2(2020), Seite 100041- (DE-627)1698858809 26666219 nnns volume:2 year:2020 pages:100041- https://doi.org/10.1016/j.cpccr.2020.100041 kostenfrei https://doaj.org/article/9759c0746d8345adae0cfbeeeae1dba3 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666621920300417 kostenfrei https://doaj.org/toc/2666-6219 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2020 100041-
language	English
source	In Current Problems in Cancer: Case Reports 2(2020), Seite 100041- volume:2 year:2020 pages:100041-
sourceStr	In Current Problems in Cancer: Case Reports 2(2020), Seite 100041- volume:2 year:2020 pages:100041-
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens
isfreeaccess_bool	true
container_title	Current Problems in Cancer: Case Reports
authorswithroles_txt_mv	Olutayo A. Sogunro @@aut@@ Rachael Steinhauer @@aut@@ Eugene Lewis @@aut@@
publishDateDaySort_date	2020-01-01T00:00:00Z
hierarchy_top_id	1698858809
id	DOAJ060330031
language_de	englisch
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callnumber-first	R - Medicine
author	Olutayo A. Sogunro
spellingShingle	Olutayo A. Sogunro misc RC254-282 misc T-cell rich B-cell lymphoma misc Large B-cell lymphoma misc R-CHOP therapy misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make
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topic_title	RC254-282 T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make T-cell rich B-cell lymphoma Large B-cell lymphoma R-CHOP therapy
topic	misc RC254-282 misc T-cell rich B-cell lymphoma misc Large B-cell lymphoma misc R-CHOP therapy misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RC254-282 misc T-cell rich B-cell lymphoma misc Large B-cell lymphoma misc R-CHOP therapy misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make
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title_full	T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make
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title_sort	cell/histiocyte rich b-cell lymphoma: a difficult diagnosis to make
callnumber	RC254-282
title_auth	T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make
abstract	Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma.
abstractGer	Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma.
abstract_unstemmed	Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Rarely, DLBCL appears on a background of T-cell and histiocyte-rich stroma, referred to as T-cell/histiocyte rich large B cell lymphoma (T/HRBCL). It is distinguished by its aggressive clinical course and high rates of extranodal malignancy. It is a difficult diagnosis to make.We present a case of a 55-year-old male who presented with an upper gastrointestinal bleed and septic shock. CT imaging of the abdomen revealed a mass arising from the fundus of the stomach infiltrating the spleen. He underwent an exploratory laparotomy, splenectomy, gastric wedge resection of the fundus, and a distal pancreatectomy, with pathological specimens revealing T-cell rich B cell lymphoma. He is being treated with R-CHOP therapy. This case illustrates the importance of understanding the clinical presentations, immunohistochemical analysis, and the diagnostic and therapeutic challenges of a patient with T-cell/histiocyte rich large B cell lymphoma.
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title_short	T cell/histiocyte rich B-cell lymphoma: A difficult diagnosis to make
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