Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review

Mitochondria are the primary organelles which can produce adenosine triphosphate (ATP). They play vital roles in maintaining normal functions. They also regulated apoptotic pathways of cancer cells. Given that, designing therapeutic agents that precisely target mitochondria is of great importance fo...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Zeng Zeng [verfasserIn] Chao Fang [verfasserIn] Ying Zhang [verfasserIn] Cong-Xian Chen [verfasserIn] Yi-Feng Zhang [verfasserIn] Kun Zhang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	mitochondria nanocarriers phototherapy chemotherapy combined immunotherapy

Übergeordnetes Werk:	In: Frontiers in Bioengineering and Biotechnology - Frontiers Media S.A., 2014, 9(2021)
Übergeordnetes Werk:	volume:9 ; year:2021

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fbioe.2021.784602

Katalog-ID:	DOAJ061097276

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spelling	10.3389/fbioe.2021.784602 doi (DE-627)DOAJ061097276 (DE-599)DOAJ13855fc1deda43b9b89b7c9c65c915dc DE-627 ger DE-627 rakwb eng TP248.13-248.65 Zeng Zeng verfasserin aut Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Mitochondria are the primary organelles which can produce adenosine triphosphate (ATP). They play vital roles in maintaining normal functions. They also regulated apoptotic pathways of cancer cells. Given that, designing therapeutic agents that precisely target mitochondria is of great importance for cancer treatment. Nanocarriers can combine the mitochondria with other therapeutic modalities in cancer treatment, thus showing great potential to cancer therapy in the past few years. Herein, we summarized lipophilic cation- and peptide-based nanosystems for mitochondria targeting. This review described how mitochondria-targeted nanocarriers promoted highly efficient cancer treatment in photodynamic therapy (PDT), chemotherapy, combined immunotherapy, and sonodynamic therapy (SDT). We further discussed mitochondria-targeted nanocarriers’ major challenges and future prospects in clinical cancer treatment. mitochondria nanocarriers phototherapy chemotherapy combined immunotherapy Biotechnology Chao Fang verfasserin aut Ying Zhang verfasserin aut Cong-Xian Chen verfasserin aut Yi-Feng Zhang verfasserin aut Kun Zhang verfasserin aut In Frontiers in Bioengineering and Biotechnology Frontiers Media S.A., 2014 9(2021) (DE-627)74950403X (DE-600)2719493-0 22964185 nnns volume:9 year:2021 https://doi.org/10.3389/fbioe.2021.784602 kostenfrei https://doaj.org/article/13855fc1deda43b9b89b7c9c65c915dc kostenfrei https://www.frontiersin.org/articles/10.3389/fbioe.2021.784602/full kostenfrei https://doaj.org/toc/2296-4185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2021
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callnumber-first	T - Technology
author	Zeng Zeng
spellingShingle	Zeng Zeng misc TP248.13-248.65 misc mitochondria misc nanocarriers misc phototherapy misc chemotherapy misc combined immunotherapy misc Biotechnology Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review
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topic_title	TP248.13-248.65 Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review mitochondria nanocarriers phototherapy chemotherapy combined immunotherapy
topic	misc TP248.13-248.65 misc mitochondria misc nanocarriers misc phototherapy misc chemotherapy misc combined immunotherapy misc Biotechnology
topic_unstemmed	misc TP248.13-248.65 misc mitochondria misc nanocarriers misc phototherapy misc chemotherapy misc combined immunotherapy misc Biotechnology
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title	Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review
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title_full	Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review
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author_browse	Zeng Zeng Chao Fang Ying Zhang Cong-Xian Chen Yi-Feng Zhang Kun Zhang
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title_sort	mitochondria-targeted nanocarriers promote highly efficient cancer therapy: a review
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title_auth	Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review
abstract	Mitochondria are the primary organelles which can produce adenosine triphosphate (ATP). They play vital roles in maintaining normal functions. They also regulated apoptotic pathways of cancer cells. Given that, designing therapeutic agents that precisely target mitochondria is of great importance for cancer treatment. Nanocarriers can combine the mitochondria with other therapeutic modalities in cancer treatment, thus showing great potential to cancer therapy in the past few years. Herein, we summarized lipophilic cation- and peptide-based nanosystems for mitochondria targeting. This review described how mitochondria-targeted nanocarriers promoted highly efficient cancer treatment in photodynamic therapy (PDT), chemotherapy, combined immunotherapy, and sonodynamic therapy (SDT). We further discussed mitochondria-targeted nanocarriers’ major challenges and future prospects in clinical cancer treatment.
abstractGer	Mitochondria are the primary organelles which can produce adenosine triphosphate (ATP). They play vital roles in maintaining normal functions. They also regulated apoptotic pathways of cancer cells. Given that, designing therapeutic agents that precisely target mitochondria is of great importance for cancer treatment. Nanocarriers can combine the mitochondria with other therapeutic modalities in cancer treatment, thus showing great potential to cancer therapy in the past few years. Herein, we summarized lipophilic cation- and peptide-based nanosystems for mitochondria targeting. This review described how mitochondria-targeted nanocarriers promoted highly efficient cancer treatment in photodynamic therapy (PDT), chemotherapy, combined immunotherapy, and sonodynamic therapy (SDT). We further discussed mitochondria-targeted nanocarriers’ major challenges and future prospects in clinical cancer treatment.
abstract_unstemmed	Mitochondria are the primary organelles which can produce adenosine triphosphate (ATP). They play vital roles in maintaining normal functions. They also regulated apoptotic pathways of cancer cells. Given that, designing therapeutic agents that precisely target mitochondria is of great importance for cancer treatment. Nanocarriers can combine the mitochondria with other therapeutic modalities in cancer treatment, thus showing great potential to cancer therapy in the past few years. Herein, we summarized lipophilic cation- and peptide-based nanosystems for mitochondria targeting. This review described how mitochondria-targeted nanocarriers promoted highly efficient cancer treatment in photodynamic therapy (PDT), chemotherapy, combined immunotherapy, and sonodynamic therapy (SDT). We further discussed mitochondria-targeted nanocarriers’ major challenges and future prospects in clinical cancer treatment.
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title_short	Mitochondria-Targeted Nanocarriers Promote Highly Efficient Cancer Therapy: A Review
url	https://doi.org/10.3389/fbioe.2021.784602 https://doaj.org/article/13855fc1deda43b9b89b7c9c65c915dc https://www.frontiersin.org/articles/10.3389/fbioe.2021.784602/full https://doaj.org/toc/2296-4185
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up_date	2024-07-03T18:49:11.643Z
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