Biomaterials in percutaneous vertebroplasty

Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Dan Răzvan BENTIA [verfasserIn] Gabriel IACOB [verfasserIn] Alexandru Vlad CIUREA [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty

Übergeordnetes Werk:	In: Romanian Journal of Medical Practice - Amaltea Medical Publishing House, 2019, 12(2017), 4, Seite 212-219
Übergeordnetes Werk:	volume:12 ; year:2017 ; number:4 ; pages:212-219

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.37897/RJMP.2017.4.7

Katalog-ID:	DOAJ061155349

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allfields	10.37897/RJMP.2017.4.7 doi (DE-627)DOAJ061155349 (DE-599)DOAJf750f5d1257c4c2daaf53f394cbcdbbe DE-627 ger DE-627 rakwb eng R5-920 Dan Răzvan BENTIA verfasserin aut Biomaterials in percutaneous vertebroplasty 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials. biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty Medicine R Medicine (General) Gabriel IACOB verfasserin aut Alexandru Vlad CIUREA verfasserin aut In Romanian Journal of Medical Practice Amaltea Medical Publishing House, 2019 12(2017), 4, Seite 212-219 (DE-627)634381776 (DE-600)2570962-8 20696108 nnns volume:12 year:2017 number:4 pages:212-219 https://doi.org/10.37897/RJMP.2017.4.7 kostenfrei https://doaj.org/article/f750f5d1257c4c2daaf53f394cbcdbbe kostenfrei https://rjmp.com.ro/articles/2017.4/RJMP_2017_4_Art-07.pdf kostenfrei https://doaj.org/toc/1842-8258 Journal toc kostenfrei https://doaj.org/toc/2069-6108 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2017 4 212-219
spelling	10.37897/RJMP.2017.4.7 doi (DE-627)DOAJ061155349 (DE-599)DOAJf750f5d1257c4c2daaf53f394cbcdbbe DE-627 ger DE-627 rakwb eng R5-920 Dan Răzvan BENTIA verfasserin aut Biomaterials in percutaneous vertebroplasty 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials. biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty Medicine R Medicine (General) Gabriel IACOB verfasserin aut Alexandru Vlad CIUREA verfasserin aut In Romanian Journal of Medical Practice Amaltea Medical Publishing House, 2019 12(2017), 4, Seite 212-219 (DE-627)634381776 (DE-600)2570962-8 20696108 nnns volume:12 year:2017 number:4 pages:212-219 https://doi.org/10.37897/RJMP.2017.4.7 kostenfrei https://doaj.org/article/f750f5d1257c4c2daaf53f394cbcdbbe kostenfrei https://rjmp.com.ro/articles/2017.4/RJMP_2017_4_Art-07.pdf kostenfrei https://doaj.org/toc/1842-8258 Journal toc kostenfrei https://doaj.org/toc/2069-6108 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2017 4 212-219
allfields_unstemmed	10.37897/RJMP.2017.4.7 doi (DE-627)DOAJ061155349 (DE-599)DOAJf750f5d1257c4c2daaf53f394cbcdbbe DE-627 ger DE-627 rakwb eng R5-920 Dan Răzvan BENTIA verfasserin aut Biomaterials in percutaneous vertebroplasty 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials. biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty Medicine R Medicine (General) Gabriel IACOB verfasserin aut Alexandru Vlad CIUREA verfasserin aut In Romanian Journal of Medical Practice Amaltea Medical Publishing House, 2019 12(2017), 4, Seite 212-219 (DE-627)634381776 (DE-600)2570962-8 20696108 nnns volume:12 year:2017 number:4 pages:212-219 https://doi.org/10.37897/RJMP.2017.4.7 kostenfrei https://doaj.org/article/f750f5d1257c4c2daaf53f394cbcdbbe kostenfrei https://rjmp.com.ro/articles/2017.4/RJMP_2017_4_Art-07.pdf kostenfrei https://doaj.org/toc/1842-8258 Journal toc kostenfrei https://doaj.org/toc/2069-6108 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2017 4 212-219
allfieldsGer	10.37897/RJMP.2017.4.7 doi (DE-627)DOAJ061155349 (DE-599)DOAJf750f5d1257c4c2daaf53f394cbcdbbe DE-627 ger DE-627 rakwb eng R5-920 Dan Răzvan BENTIA verfasserin aut Biomaterials in percutaneous vertebroplasty 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials. biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty Medicine R Medicine (General) Gabriel IACOB verfasserin aut Alexandru Vlad CIUREA verfasserin aut In Romanian Journal of Medical Practice Amaltea Medical Publishing House, 2019 12(2017), 4, Seite 212-219 (DE-627)634381776 (DE-600)2570962-8 20696108 nnns volume:12 year:2017 number:4 pages:212-219 https://doi.org/10.37897/RJMP.2017.4.7 kostenfrei https://doaj.org/article/f750f5d1257c4c2daaf53f394cbcdbbe kostenfrei https://rjmp.com.ro/articles/2017.4/RJMP_2017_4_Art-07.pdf kostenfrei https://doaj.org/toc/1842-8258 Journal toc kostenfrei https://doaj.org/toc/2069-6108 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2017 4 212-219
allfieldsSound	10.37897/RJMP.2017.4.7 doi (DE-627)DOAJ061155349 (DE-599)DOAJf750f5d1257c4c2daaf53f394cbcdbbe DE-627 ger DE-627 rakwb eng R5-920 Dan Răzvan BENTIA verfasserin aut Biomaterials in percutaneous vertebroplasty 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials. biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty Medicine R Medicine (General) Gabriel IACOB verfasserin aut Alexandru Vlad CIUREA verfasserin aut In Romanian Journal of Medical Practice Amaltea Medical Publishing House, 2019 12(2017), 4, Seite 212-219 (DE-627)634381776 (DE-600)2570962-8 20696108 nnns volume:12 year:2017 number:4 pages:212-219 https://doi.org/10.37897/RJMP.2017.4.7 kostenfrei https://doaj.org/article/f750f5d1257c4c2daaf53f394cbcdbbe kostenfrei https://rjmp.com.ro/articles/2017.4/RJMP_2017_4_Art-07.pdf kostenfrei https://doaj.org/toc/1842-8258 Journal toc kostenfrei https://doaj.org/toc/2069-6108 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2017 4 212-219
language	English
source	In Romanian Journal of Medical Practice 12(2017), 4, Seite 212-219 volume:12 year:2017 number:4 pages:212-219
sourceStr	In Romanian Journal of Medical Practice 12(2017), 4, Seite 212-219 volume:12 year:2017 number:4 pages:212-219
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topic_facet	biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty Medicine R Medicine (General)
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authorswithroles_txt_mv	Dan Răzvan BENTIA @@aut@@ Gabriel IACOB @@aut@@ Alexandru Vlad CIUREA @@aut@@
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topic_title	R5-920 Biomaterials in percutaneous vertebroplasty biomaterials vertebral fractures vertebral metastases vertebral tumors pmma percutaneous vertebroplasty
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title	Biomaterials in percutaneous vertebroplasty
ctrlnum	(DE-627)DOAJ061155349 (DE-599)DOAJf750f5d1257c4c2daaf53f394cbcdbbe
title_full	Biomaterials in percutaneous vertebroplasty
author_sort	Dan Răzvan BENTIA
journal	Romanian Journal of Medical Practice
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author_browse	Dan Răzvan BENTIA Gabriel IACOB Alexandru Vlad CIUREA
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author-letter	Dan Răzvan BENTIA
doi_str_mv	10.37897/RJMP.2017.4.7
author2-role	verfasserin
title_sort	biomaterials in percutaneous vertebroplasty
callnumber	R5-920
title_auth	Biomaterials in percutaneous vertebroplasty
abstract	Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials.
abstractGer	Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials.
abstract_unstemmed	Aim. The purpose of this study is to reveal the safety and efficacy of biomaterials used in VPP in the treatment of vertebral spinal vertebral patients and primary vertebral tumors. Material and method. The retrospective study (December 2012-December 2015) included 21 patients admitted to the Sanador Hospitals Department of Neurosurgery and Clinical Orthopedics-Traumatology and Osteoarticular TBC "Foişor", Bucharest, with VPP indication. Patients were diagnosed with vertebral spindles produced by vertebral metastases and primary vertebral tumors without compression in the vertebral canal. The diagnosis of these vertebral compressions has been established and confirmed by medical history, medical history, paraclinical investigation studies: column and face colorectal radiographs, native and contrast vertebral CT, 3D bone reconstruction and reconstruction, and native vertebral MRI contrast. Results. All VPPs have been technically successful, being well tolerated by patients, improved spinal algal symptomatology, rapid postoperative resumption of patient mobility. There were no major postoperative complications such as material migration into the canal, pulmonary embolism with material, infections, postoperative local haematomas, local or systemic reactions to VertaPlex®. All 21 patients were relieved with improved general condition without major postoperative complications. Clinical follow-up data over a 12-month period, detailed at 1, 3, 6, and 12 months after VPP and assessed with visual analogue scale, the Oswestry Disability Score Index and the Karnofsky Performance Scale have demonstrated, along with technical success, a significantly reduced rate of clinical pain, an improvement in disability and a real increase in quality of life and mobility in patients selected for study. Discussions. PMMA still prevails in choosing as a biomaterial in VPP but is not intrinsically degradable, which is a major barrier to wider applications. In order to eliminate the drawbacks of classical VPPs, new bone cements with biodegradable CPC potential have been generated, with a lower toxic potential than PMMA, and which can be improved by bone-stimulation-enhancing elements. Conclusions. VPP actually increases the quality of life of patients with vertebral spine caused by vertebral metastases and primary vertebral tumors. Biodegradability and biocompatibility, minimal exothermic reactions and insignificant contraction imply that biodegradable and mechanically assembled bone cements without graft rejection will be the future of VPP biomaterials.
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title_short	Biomaterials in percutaneous vertebroplasty
url	https://doi.org/10.37897/RJMP.2017.4.7 https://doaj.org/article/f750f5d1257c4c2daaf53f394cbcdbbe https://rjmp.com.ro/articles/2017.4/RJMP_2017_4_Art-07.pdf https://doaj.org/toc/1842-8258 https://doaj.org/toc/2069-6108
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