Numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells

Synergistic applications of an electric field combined with nanojet-based mechanical pressure, have recently been shown to help create larger pores and provide control of the aspect ratio in biological membranes. The nanojets are formed by the collapse of nanobubbles in the vicinity of biomembranes...
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Autor*in:	Q. Hu [verfasserIn] L. Zhang [verfasserIn] R. P. Joshi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Übergeordnetes Werk:	In: AIP Advances - AIP Publishing LLC, 2011, 9(2019), 4, Seite 045006-045006-5
Übergeordnetes Werk:	volume:9 ; year:2019 ; number:4 ; pages:045006-045006-5

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1063/1.5085677

Katalog-ID:	DOAJ06126041X

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callnumber-first	Q - Science
author	Q. Hu
spellingShingle	Q. Hu misc QC1-999 misc Physics Numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells
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topic_title	QC1-999 Numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells
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title	Numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells
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title_full	Numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells
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title_sort	numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells
callnumber	QC1-999
title_auth	Numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells
abstract	Synergistic applications of an electric field combined with nanojet-based mechanical pressure, have recently been shown to help create larger pores and provide control of the aspect ratio in biological membranes. The nanojets are formed by the collapse of nanobubbles in the vicinity of biomembranes upon being subjected to external shockwaves. Here we analyze the effects produced by the collapse of multiple nanobubbles in the presence of an electric field. Our simulations, based on molecular dynamics, show that not only would multiple nanobubbles make it possible to create larger pores, but also increase the pore density on the surface of biological cells. Both aspects could aid in the transport of drugs and genes for bio-medical applications.
abstractGer	Synergistic applications of an electric field combined with nanojet-based mechanical pressure, have recently been shown to help create larger pores and provide control of the aspect ratio in biological membranes. The nanojets are formed by the collapse of nanobubbles in the vicinity of biomembranes upon being subjected to external shockwaves. Here we analyze the effects produced by the collapse of multiple nanobubbles in the presence of an electric field. Our simulations, based on molecular dynamics, show that not only would multiple nanobubbles make it possible to create larger pores, but also increase the pore density on the surface of biological cells. Both aspects could aid in the transport of drugs and genes for bio-medical applications.
abstract_unstemmed	Synergistic applications of an electric field combined with nanojet-based mechanical pressure, have recently been shown to help create larger pores and provide control of the aspect ratio in biological membranes. The nanojets are formed by the collapse of nanobubbles in the vicinity of biomembranes upon being subjected to external shockwaves. Here we analyze the effects produced by the collapse of multiple nanobubbles in the presence of an electric field. Our simulations, based on molecular dynamics, show that not only would multiple nanobubbles make it possible to create larger pores, but also increase the pore density on the surface of biological cells. Both aspects could aid in the transport of drugs and genes for bio-medical applications.
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title_short	Numerical evaluations of membrane poration by shockwave induced multiple nanobubble collapse in presence of electric fields for transport through cells
url	https://doi.org/10.1063/1.5085677 https://doaj.org/article/72806d87d9b74809978be58becca7882 http://dx.doi.org/10.1063/1.5085677 https://doaj.org/toc/2158-3226
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