The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying

One of the main components for being successful in tissue engineering is developing a scaffold with an appropriate architecture for allow migration, cell proliferation, and differentiation. A gelatin-chitosan scaffold by vacuum freeze-drying has been developed for tissue engineering applications. Th...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Daniel Enrique López Angulo [verfasserIn] Paulo José do Amaral Sobral [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	tissue engineering cell proliferation interconnected pore matrix

Übergeordnetes Werk:	In: Materials Research - Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol), 2004, 19(2016), 4, Seite 839-845
Übergeordnetes Werk:	volume:19 ; year:2016 ; number:4 ; pages:839-845

Links:	Link aufrufen Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1590/1980-5373-MR-2015-0793

Katalog-ID:	DOAJ06137119X

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callnumber-first	T - Technology
author	Daniel Enrique López Angulo
spellingShingle	Daniel Enrique López Angulo misc TA401-492 misc tissue engineering misc cell proliferation misc interconnected pore matrix misc Materials of engineering and construction. Mechanics of materials The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying
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topic_title	TA401-492 The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying tissue engineering cell proliferation interconnected pore matrix
topic	misc TA401-492 misc tissue engineering misc cell proliferation misc interconnected pore matrix misc Materials of engineering and construction. Mechanics of materials
topic_unstemmed	misc TA401-492 misc tissue engineering misc cell proliferation misc interconnected pore matrix misc Materials of engineering and construction. Mechanics of materials
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title	The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying
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title_full	The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying
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title_sort	effect of processing parameters and solid concentration on the microstructure and pore architecture of gelatin-chitosan scaffolds produced by freeze-drying
callnumber	TA401-492
title_auth	The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying
abstract	One of the main components for being successful in tissue engineering is developing a scaffold with an appropriate architecture for allow migration, cell proliferation, and differentiation. A gelatin-chitosan scaffold by vacuum freeze-drying has been developed for tissue engineering applications. The effects of solid concentration and freezing processing on the scaffold morphology and porous size were investigated. As the chitosan content was increased the viscoelastic properties of pigskin gelatin was modified, the maximum G' values were lower than the values for pure gelatin solution, and the thermal transition points also occurred at lower temperatures, as well as a decrease of pore size tendency was observed and the scaffold visibly increased porosity, the structure scaffold was observed with an interconnected and more homogeneous pore matrix. The pore sizes become smaller and pore walls thinner, while interconnectivity increases along with declining pre-freezing temperature. The chitosan-gelatin scaffold will be a promising candidate in tissue engineering.
abstractGer	One of the main components for being successful in tissue engineering is developing a scaffold with an appropriate architecture for allow migration, cell proliferation, and differentiation. A gelatin-chitosan scaffold by vacuum freeze-drying has been developed for tissue engineering applications. The effects of solid concentration and freezing processing on the scaffold morphology and porous size were investigated. As the chitosan content was increased the viscoelastic properties of pigskin gelatin was modified, the maximum G' values were lower than the values for pure gelatin solution, and the thermal transition points also occurred at lower temperatures, as well as a decrease of pore size tendency was observed and the scaffold visibly increased porosity, the structure scaffold was observed with an interconnected and more homogeneous pore matrix. The pore sizes become smaller and pore walls thinner, while interconnectivity increases along with declining pre-freezing temperature. The chitosan-gelatin scaffold will be a promising candidate in tissue engineering.
abstract_unstemmed	One of the main components for being successful in tissue engineering is developing a scaffold with an appropriate architecture for allow migration, cell proliferation, and differentiation. A gelatin-chitosan scaffold by vacuum freeze-drying has been developed for tissue engineering applications. The effects of solid concentration and freezing processing on the scaffold morphology and porous size were investigated. As the chitosan content was increased the viscoelastic properties of pigskin gelatin was modified, the maximum G' values were lower than the values for pure gelatin solution, and the thermal transition points also occurred at lower temperatures, as well as a decrease of pore size tendency was observed and the scaffold visibly increased porosity, the structure scaffold was observed with an interconnected and more homogeneous pore matrix. The pore sizes become smaller and pore walls thinner, while interconnectivity increases along with declining pre-freezing temperature. The chitosan-gelatin scaffold will be a promising candidate in tissue engineering.
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title_short	The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying
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up_date	2024-07-03T20:21:28.639Z
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The Effect of Processing Parameters and Solid Concentration on the Microstructure and Pore Architecture of Gelatin-Chitosan Scaffolds Produced by Freeze-Drying

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