Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent

The consumer and cosmetic industries have recently placed a greater emphasis on ecofriendly solvents for botanical extraction, including natural deep eutectic solvents (NADES). In this study, NADES were prepared for <i<Morus alba</i< callus extraction. The efficiency of extraction from t...
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Autor*in:	Jukrapun Komaikul [verfasserIn] Supachoke Mangmool [verfasserIn] Waraporn Putalun [verfasserIn] Tharita Kitisripanya [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	natural deep eutectic solvent stilbenoids stability

Übergeordnetes Werk:	In: Cosmetics - MDPI AG, 2014, 8(2021), 3, p 91
Übergeordnetes Werk:	volume:8 ; year:2021 ; number:3, p 91

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/cosmetics8030091

Katalog-ID:	DOAJ061663042

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callnumber-first	Q - Science
author	Jukrapun Komaikul
spellingShingle	Jukrapun Komaikul misc QD1-999 misc natural deep eutectic solvent misc <i<Morus alba</i< misc stilbenoids misc stability misc Chemistry Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent
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topic_title	QD1-999 Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent natural deep eutectic solvent <i<Morus alba</i< stilbenoids stability
topic	misc QD1-999 misc natural deep eutectic solvent misc <i<Morus alba</i< misc stilbenoids misc stability misc Chemistry
topic_unstemmed	misc QD1-999 misc natural deep eutectic solvent misc <i<Morus alba</i< misc stilbenoids misc stability misc Chemistry
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title	Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent
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title_full	Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent
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title_sort	preparation of readily-to-use stilbenoids extract from <i<morus alba</i< callus using a natural deep eutectic solvent
callnumber	QD1-999
title_auth	Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent
abstract	The consumer and cosmetic industries have recently placed a greater emphasis on ecofriendly solvents for botanical extraction, including natural deep eutectic solvents (NADES). In this study, NADES were prepared for <i<Morus alba</i< callus extraction. The efficiency of extraction from the NADES and methanol was investigated by comparison of the stilbenoids yield and anti-melanogenesis activity. Prior to testing the irritability of a suitable NADES on the reconstructed human epidermis (RhE), the effect of the selected NADES on stilbenoids stability was determined. The results showed that the highest yields of stilbenoids were obtained from choline chloride-glycerol mixtures (Ch1G2) and methanol extracts, with no significant difference in yields (5.06 ± 0.05 and 6.32 ± 0.40 mg/g callus dry weight, respectively). The NADES extracts of <i<M. alba</i< callus showed comparable anti-melanogenesis activity compared to methanol. In term of stability, stilbenoids in Ch1G2 remained stable after six months of storage at 4 °C except resveratrol. Furthermore, Ch1G2 had no irritation effect on RhE. Thus, based on the findings of this study, Ch1G2 is an intriguing green solvent alternative for the extraction of <i<M. alba</i< callus and may be advantageous for the preparation of skin-lightening cosmetics.
abstractGer	The consumer and cosmetic industries have recently placed a greater emphasis on ecofriendly solvents for botanical extraction, including natural deep eutectic solvents (NADES). In this study, NADES were prepared for <i<Morus alba</i< callus extraction. The efficiency of extraction from the NADES and methanol was investigated by comparison of the stilbenoids yield and anti-melanogenesis activity. Prior to testing the irritability of a suitable NADES on the reconstructed human epidermis (RhE), the effect of the selected NADES on stilbenoids stability was determined. The results showed that the highest yields of stilbenoids were obtained from choline chloride-glycerol mixtures (Ch1G2) and methanol extracts, with no significant difference in yields (5.06 ± 0.05 and 6.32 ± 0.40 mg/g callus dry weight, respectively). The NADES extracts of <i<M. alba</i< callus showed comparable anti-melanogenesis activity compared to methanol. In term of stability, stilbenoids in Ch1G2 remained stable after six months of storage at 4 °C except resveratrol. Furthermore, Ch1G2 had no irritation effect on RhE. Thus, based on the findings of this study, Ch1G2 is an intriguing green solvent alternative for the extraction of <i<M. alba</i< callus and may be advantageous for the preparation of skin-lightening cosmetics.
abstract_unstemmed	The consumer and cosmetic industries have recently placed a greater emphasis on ecofriendly solvents for botanical extraction, including natural deep eutectic solvents (NADES). In this study, NADES were prepared for <i<Morus alba</i< callus extraction. The efficiency of extraction from the NADES and methanol was investigated by comparison of the stilbenoids yield and anti-melanogenesis activity. Prior to testing the irritability of a suitable NADES on the reconstructed human epidermis (RhE), the effect of the selected NADES on stilbenoids stability was determined. The results showed that the highest yields of stilbenoids were obtained from choline chloride-glycerol mixtures (Ch1G2) and methanol extracts, with no significant difference in yields (5.06 ± 0.05 and 6.32 ± 0.40 mg/g callus dry weight, respectively). The NADES extracts of <i<M. alba</i< callus showed comparable anti-melanogenesis activity compared to methanol. In term of stability, stilbenoids in Ch1G2 remained stable after six months of storage at 4 °C except resveratrol. Furthermore, Ch1G2 had no irritation effect on RhE. Thus, based on the findings of this study, Ch1G2 is an intriguing green solvent alternative for the extraction of <i<M. alba</i< callus and may be advantageous for the preparation of skin-lightening cosmetics.
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title_short	Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent
url	https://doi.org/10.3390/cosmetics8030091 https://doaj.org/article/f8c5e39a9dae4689820e5223e0d5acc0 https://www.mdpi.com/2079-9284/8/3/91 https://doaj.org/toc/2079-9284
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Preparation of Readily-to-Use Stilbenoids Extract from <i<Morus alba</i< Callus Using a Natural Deep Eutectic Solvent

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