The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats
Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of...
Ausführliche Beschreibung
Autor*in: |
Roshan-Milani S. [verfasserIn] Khalilpour J. [verfasserIn] Fard A. Abdollahzade [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Übergeordnetes Werk: |
In: Acta Medica Bulgarica - Sciendo, 2015, 46(2019), 2, Seite 41-46 |
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Übergeordnetes Werk: |
volume:46 ; year:2019 ; number:2 ; pages:41-46 |
Links: |
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DOI / URN: |
10.2478/amb-2019-0017 |
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Katalog-ID: |
DOAJ061987956 |
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10.2478/amb-2019-0017 doi (DE-627)DOAJ061987956 (DE-599)DOAJd37568e71c8444bbbb5bf2c8fc19d5ec DE-627 ger DE-627 rakwb eng Roshan-Milani S. verfasserin aut The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of heparanase inhibition in a diabetic experimental model. heparanase diabetic nephropathy sulodexide urine protein urine glycosaminoglycan Medicine R Khalilpour J. verfasserin aut Fard A. Abdollahzade verfasserin aut In Acta Medica Bulgarica Sciendo, 2015 46(2019), 2, Seite 41-46 (DE-627)DOAJ000088196 27195384 nnns volume:46 year:2019 number:2 pages:41-46 https://doi.org/10.2478/amb-2019-0017 kostenfrei https://doaj.org/article/d37568e71c8444bbbb5bf2c8fc19d5ec kostenfrei https://doi.org/10.2478/amb-2019-0017 kostenfrei https://doaj.org/toc/0324-1750 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 46 2019 2 41-46 |
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The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats heparanase diabetic nephropathy sulodexide urine protein urine glycosaminoglycan |
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The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats |
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Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of heparanase inhibition in a diabetic experimental model. |
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Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of heparanase inhibition in a diabetic experimental model. |
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Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present study was to investigate the renal effects of heparanase inhibition in a diabetic experimental model. |
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The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats |
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