Biomarker Testing: Piercing the Fog of Alzheimer’s and Related Dementia
Alzheimer’s disease (AD) and related dementia is one of the growing threats to the sustainability of health and care systems in developed countries, and efforts to find therapies have had scant success. The main reasons for this are lack of efficient therapy, which is linked to too late discovery of...
Ausführliche Beschreibung
Autor*in: |
Denis Horgan [verfasserIn] Flavio Nobili [verfasserIn] Charlotte Teunissen [verfasserIn] Timo Grimmer [verfasserIn] Dinko Mitrecic [verfasserIn] Laurence Ris [verfasserIn] Zvezdan Pirtosek [verfasserIn] Chiara Bernini [verfasserIn] Antonio Federico [verfasserIn] Daniel Blackburn [verfasserIn] Giancarlo Logroscino [verfasserIn] Nikos Scarmeas [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Schlagwörter: |
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Übergeordnetes Werk: |
In: Biomedicine Hub - Karger Publishers, 2017, 5(2020), 3, Seite 84-105 |
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Übergeordnetes Werk: |
volume:5 ; year:2020 ; number:3 ; pages:84-105 |
Links: |
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DOI / URN: |
10.1159/000511233 |
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Katalog-ID: |
DOAJ062176781 |
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10.1159/000511233 doi (DE-627)DOAJ062176781 (DE-599)DOAJ2e04db777455481cb93a6a4fea6d5e24 DE-627 ger DE-627 rakwb eng R5-920 Denis Horgan verfasserin aut Biomarker Testing: Piercing the Fog of Alzheimer’s and Related Dementia 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Alzheimer’s disease (AD) and related dementia is one of the growing threats to the sustainability of health and care systems in developed countries, and efforts to find therapies have had scant success. The main reasons for this are lack of efficient therapy, which is linked to too late discovery of the disease itself. With this in mind, biomarkers are recognised as an element which can bring a major contribution to research, helping elucidate the disease and the search for treatments. They are also playing an increasing role in early detection and timely diagnosis, which are considered the principal hopes of effective management in the absence of an effective drug. The current arsenal of biomarkers could already, if more widely deployed, provide an effective minimum service to patients and health systems. A concerted action by policy makers and stakeholders could drive progress in access to AD biomarker testing to provide an optimum service in the medium term. This paper discusses how to improve the use of and access to biomarker testing in the detection and diagnosis of AD and other diseases featuring dementia, and how EU healthcare systems could benefit. It outlines the challenges, lists the achievements to date, and highlights the actions needed to allow biomarker testing to deliver more fully on their potential in AD. alzheimer’s disease biomarkers diagnosis Medicine (General) Flavio Nobili verfasserin aut Charlotte Teunissen verfasserin aut Timo Grimmer verfasserin aut Dinko Mitrecic verfasserin aut Laurence Ris verfasserin aut Zvezdan Pirtosek verfasserin aut Chiara Bernini verfasserin aut Antonio Federico verfasserin aut Daniel Blackburn verfasserin aut Giancarlo Logroscino verfasserin aut Nikos Scarmeas verfasserin aut In Biomedicine Hub Karger Publishers, 2017 5(2020), 3, Seite 84-105 (DE-627)859340082 (DE-600)2855840-6 22966870 nnns volume:5 year:2020 number:3 pages:84-105 https://doi.org/10.1159/000511233 kostenfrei https://doaj.org/article/2e04db777455481cb93a6a4fea6d5e24 kostenfrei https://www.karger.com/Article/FullText/511233 kostenfrei https://doaj.org/toc/2296-6870 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2020 3 84-105 |
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10.1159/000511233 doi (DE-627)DOAJ062176781 (DE-599)DOAJ2e04db777455481cb93a6a4fea6d5e24 DE-627 ger DE-627 rakwb eng R5-920 Denis Horgan verfasserin aut Biomarker Testing: Piercing the Fog of Alzheimer’s and Related Dementia 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Alzheimer’s disease (AD) and related dementia is one of the growing threats to the sustainability of health and care systems in developed countries, and efforts to find therapies have had scant success. The main reasons for this are lack of efficient therapy, which is linked to too late discovery of the disease itself. With this in mind, biomarkers are recognised as an element which can bring a major contribution to research, helping elucidate the disease and the search for treatments. They are also playing an increasing role in early detection and timely diagnosis, which are considered the principal hopes of effective management in the absence of an effective drug. The current arsenal of biomarkers could already, if more widely deployed, provide an effective minimum service to patients and health systems. A concerted action by policy makers and stakeholders could drive progress in access to AD biomarker testing to provide an optimum service in the medium term. This paper discusses how to improve the use of and access to biomarker testing in the detection and diagnosis of AD and other diseases featuring dementia, and how EU healthcare systems could benefit. It outlines the challenges, lists the achievements to date, and highlights the actions needed to allow biomarker testing to deliver more fully on their potential in AD. alzheimer’s disease biomarkers diagnosis Medicine (General) Flavio Nobili verfasserin aut Charlotte Teunissen verfasserin aut Timo Grimmer verfasserin aut Dinko Mitrecic verfasserin aut Laurence Ris verfasserin aut Zvezdan Pirtosek verfasserin aut Chiara Bernini verfasserin aut Antonio Federico verfasserin aut Daniel Blackburn verfasserin aut Giancarlo Logroscino verfasserin aut Nikos Scarmeas verfasserin aut In Biomedicine Hub Karger Publishers, 2017 5(2020), 3, Seite 84-105 (DE-627)859340082 (DE-600)2855840-6 22966870 nnns volume:5 year:2020 number:3 pages:84-105 https://doi.org/10.1159/000511233 kostenfrei https://doaj.org/article/2e04db777455481cb93a6a4fea6d5e24 kostenfrei https://www.karger.com/Article/FullText/511233 kostenfrei https://doaj.org/toc/2296-6870 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2020 3 84-105 |
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Alzheimer’s disease (AD) and related dementia is one of the growing threats to the sustainability of health and care systems in developed countries, and efforts to find therapies have had scant success. The main reasons for this are lack of efficient therapy, which is linked to too late discovery of the disease itself. With this in mind, biomarkers are recognised as an element which can bring a major contribution to research, helping elucidate the disease and the search for treatments. They are also playing an increasing role in early detection and timely diagnosis, which are considered the principal hopes of effective management in the absence of an effective drug. The current arsenal of biomarkers could already, if more widely deployed, provide an effective minimum service to patients and health systems. A concerted action by policy makers and stakeholders could drive progress in access to AD biomarker testing to provide an optimum service in the medium term. This paper discusses how to improve the use of and access to biomarker testing in the detection and diagnosis of AD and other diseases featuring dementia, and how EU healthcare systems could benefit. It outlines the challenges, lists the achievements to date, and highlights the actions needed to allow biomarker testing to deliver more fully on their potential in AD. |
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Alzheimer’s disease (AD) and related dementia is one of the growing threats to the sustainability of health and care systems in developed countries, and efforts to find therapies have had scant success. The main reasons for this are lack of efficient therapy, which is linked to too late discovery of the disease itself. With this in mind, biomarkers are recognised as an element which can bring a major contribution to research, helping elucidate the disease and the search for treatments. They are also playing an increasing role in early detection and timely diagnosis, which are considered the principal hopes of effective management in the absence of an effective drug. The current arsenal of biomarkers could already, if more widely deployed, provide an effective minimum service to patients and health systems. A concerted action by policy makers and stakeholders could drive progress in access to AD biomarker testing to provide an optimum service in the medium term. This paper discusses how to improve the use of and access to biomarker testing in the detection and diagnosis of AD and other diseases featuring dementia, and how EU healthcare systems could benefit. It outlines the challenges, lists the achievements to date, and highlights the actions needed to allow biomarker testing to deliver more fully on their potential in AD. |
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Alzheimer’s disease (AD) and related dementia is one of the growing threats to the sustainability of health and care systems in developed countries, and efforts to find therapies have had scant success. The main reasons for this are lack of efficient therapy, which is linked to too late discovery of the disease itself. With this in mind, biomarkers are recognised as an element which can bring a major contribution to research, helping elucidate the disease and the search for treatments. They are also playing an increasing role in early detection and timely diagnosis, which are considered the principal hopes of effective management in the absence of an effective drug. The current arsenal of biomarkers could already, if more widely deployed, provide an effective minimum service to patients and health systems. A concerted action by policy makers and stakeholders could drive progress in access to AD biomarker testing to provide an optimum service in the medium term. This paper discusses how to improve the use of and access to biomarker testing in the detection and diagnosis of AD and other diseases featuring dementia, and how EU healthcare systems could benefit. It outlines the challenges, lists the achievements to date, and highlights the actions needed to allow biomarker testing to deliver more fully on their potential in AD. |
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