Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda

Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depress...
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Autor*in:	Scholastic Ashaba [verfasserIn] Christine E. Cooper-Vince [verfasserIn] Samuel Maling [verfasserIn] Emily N. Satinsky [verfasserIn] Charles Baguma [verfasserIn] Dickens Akena [verfasserIn] Denis Nansera [verfasserIn] Francis Bajunirwe [verfasserIn] Alexander C. Tsai [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda

Übergeordnetes Werk:	In: Journal of Affective Disorders Reports - Elsevier, 2021, 4(2021), Seite 100094-
Übergeordnetes Werk:	volume:4 ; year:2021 ; pages:100094-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.jadr.2021.100094

Katalog-ID:	DOAJ062815350

Internformat


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520			\|a Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes.
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650		4	\|a Sub-Saharan Africa
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700	0		\|a Charles Baguma \|e verfasserin \|4 aut
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700	0		\|a Denis Nansera \|e verfasserin \|4 aut
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700	0		\|a Alexander C. Tsai \|e verfasserin \|4 aut
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allfields	10.1016/j.jadr.2021.100094 doi (DE-627)DOAJ062815350 (DE-599)DOAJ915689db083d4b86aeb5757a31617666 DE-627 ger DE-627 rakwb eng RZ400-408 Scholastic Ashaba verfasserin aut Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes. Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda Mental healing Christine E. Cooper-Vince verfasserin aut Samuel Maling verfasserin aut Emily N. Satinsky verfasserin aut Charles Baguma verfasserin aut Dickens Akena verfasserin aut Denis Nansera verfasserin aut Francis Bajunirwe verfasserin aut Alexander C. Tsai verfasserin aut In Journal of Affective Disorders Reports Elsevier, 2021 4(2021), Seite 100094- (DE-627)1747967335 26669153 nnns volume:4 year:2021 pages:100094- https://doi.org/10.1016/j.jadr.2021.100094 kostenfrei https://doaj.org/article/915689db083d4b86aeb5757a31617666 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666915321000214 kostenfrei https://doaj.org/toc/2666-9153 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 4 2021 100094-
spelling	10.1016/j.jadr.2021.100094 doi (DE-627)DOAJ062815350 (DE-599)DOAJ915689db083d4b86aeb5757a31617666 DE-627 ger DE-627 rakwb eng RZ400-408 Scholastic Ashaba verfasserin aut Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes. Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda Mental healing Christine E. Cooper-Vince verfasserin aut Samuel Maling verfasserin aut Emily N. Satinsky verfasserin aut Charles Baguma verfasserin aut Dickens Akena verfasserin aut Denis Nansera verfasserin aut Francis Bajunirwe verfasserin aut Alexander C. Tsai verfasserin aut In Journal of Affective Disorders Reports Elsevier, 2021 4(2021), Seite 100094- (DE-627)1747967335 26669153 nnns volume:4 year:2021 pages:100094- https://doi.org/10.1016/j.jadr.2021.100094 kostenfrei https://doaj.org/article/915689db083d4b86aeb5757a31617666 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666915321000214 kostenfrei https://doaj.org/toc/2666-9153 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 4 2021 100094-
allfields_unstemmed	10.1016/j.jadr.2021.100094 doi (DE-627)DOAJ062815350 (DE-599)DOAJ915689db083d4b86aeb5757a31617666 DE-627 ger DE-627 rakwb eng RZ400-408 Scholastic Ashaba verfasserin aut Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes. Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda Mental healing Christine E. Cooper-Vince verfasserin aut Samuel Maling verfasserin aut Emily N. Satinsky verfasserin aut Charles Baguma verfasserin aut Dickens Akena verfasserin aut Denis Nansera verfasserin aut Francis Bajunirwe verfasserin aut Alexander C. Tsai verfasserin aut In Journal of Affective Disorders Reports Elsevier, 2021 4(2021), Seite 100094- (DE-627)1747967335 26669153 nnns volume:4 year:2021 pages:100094- https://doi.org/10.1016/j.jadr.2021.100094 kostenfrei https://doaj.org/article/915689db083d4b86aeb5757a31617666 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666915321000214 kostenfrei https://doaj.org/toc/2666-9153 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 4 2021 100094-
allfieldsGer	10.1016/j.jadr.2021.100094 doi (DE-627)DOAJ062815350 (DE-599)DOAJ915689db083d4b86aeb5757a31617666 DE-627 ger DE-627 rakwb eng RZ400-408 Scholastic Ashaba verfasserin aut Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes. Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda Mental healing Christine E. Cooper-Vince verfasserin aut Samuel Maling verfasserin aut Emily N. Satinsky verfasserin aut Charles Baguma verfasserin aut Dickens Akena verfasserin aut Denis Nansera verfasserin aut Francis Bajunirwe verfasserin aut Alexander C. Tsai verfasserin aut In Journal of Affective Disorders Reports Elsevier, 2021 4(2021), Seite 100094- (DE-627)1747967335 26669153 nnns volume:4 year:2021 pages:100094- https://doi.org/10.1016/j.jadr.2021.100094 kostenfrei https://doaj.org/article/915689db083d4b86aeb5757a31617666 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666915321000214 kostenfrei https://doaj.org/toc/2666-9153 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 4 2021 100094-
allfieldsSound	10.1016/j.jadr.2021.100094 doi (DE-627)DOAJ062815350 (DE-599)DOAJ915689db083d4b86aeb5757a31617666 DE-627 ger DE-627 rakwb eng RZ400-408 Scholastic Ashaba verfasserin aut Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes. Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda Mental healing Christine E. Cooper-Vince verfasserin aut Samuel Maling verfasserin aut Emily N. Satinsky verfasserin aut Charles Baguma verfasserin aut Dickens Akena verfasserin aut Denis Nansera verfasserin aut Francis Bajunirwe verfasserin aut Alexander C. Tsai verfasserin aut In Journal of Affective Disorders Reports Elsevier, 2021 4(2021), Seite 100094- (DE-627)1747967335 26669153 nnns volume:4 year:2021 pages:100094- https://doi.org/10.1016/j.jadr.2021.100094 kostenfrei https://doaj.org/article/915689db083d4b86aeb5757a31617666 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666915321000214 kostenfrei https://doaj.org/toc/2666-9153 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 4 2021 100094-
language	English
source	In Journal of Affective Disorders Reports 4(2021), Seite 100094- volume:4 year:2021 pages:100094-
sourceStr	In Journal of Affective Disorders Reports 4(2021), Seite 100094- volume:4 year:2021 pages:100094-
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda Mental healing
isfreeaccess_bool	true
container_title	Journal of Affective Disorders Reports
authorswithroles_txt_mv	Scholastic Ashaba @@aut@@ Christine E. Cooper-Vince @@aut@@ Samuel Maling @@aut@@ Emily N. Satinsky @@aut@@ Charles Baguma @@aut@@ Dickens Akena @@aut@@ Denis Nansera @@aut@@ Francis Bajunirwe @@aut@@ Alexander C. Tsai @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	1747967335
id	DOAJ062815350
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ062815350</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230309023224.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2021 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jadr.2021.100094</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ062815350</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ915689db083d4b86aeb5757a31617666</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RZ400-408</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Scholastic Ashaba</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Adolescents</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Adverse childhood experiences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">HIV</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Mental health</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sub-Saharan Africa</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Uganda</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Mental healing</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Christine E. 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callnumber-first	R - Medicine
author	Scholastic Ashaba
spellingShingle	Scholastic Ashaba misc RZ400-408 misc Adolescents misc Adverse childhood experiences misc HIV misc Mental health misc Sub-Saharan Africa misc Uganda misc Mental healing Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda
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topic_title	RZ400-408 Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda Adolescents Adverse childhood experiences HIV Mental health Sub-Saharan Africa Uganda
topic	misc RZ400-408 misc Adolescents misc Adverse childhood experiences misc HIV misc Mental health misc Sub-Saharan Africa misc Uganda misc Mental healing
topic_unstemmed	misc RZ400-408 misc Adolescents misc Adverse childhood experiences misc HIV misc Mental health misc Sub-Saharan Africa misc Uganda misc Mental healing
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title	Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda
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title_full	Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda
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author_browse	Scholastic Ashaba Christine E. Cooper-Vince Samuel Maling Emily N. Satinsky Charles Baguma Dickens Akena Denis Nansera Francis Bajunirwe Alexander C. Tsai
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title_sort	childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with hiv in rural uganda
callnumber	RZ400-408
title_auth	Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda
abstract	Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes.
abstractGer	Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes.
abstract_unstemmed	Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes.
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title_short	Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda
url	https://doi.org/10.1016/j.jadr.2021.100094 https://doaj.org/article/915689db083d4b86aeb5757a31617666 http://www.sciencedirect.com/science/article/pii/S2666915321000214 https://doaj.org/toc/2666-9153
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up_date	2024-07-03T14:12:26.399Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ062815350</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230309023224.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2021 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jadr.2021.100094</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ062815350</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ915689db083d4b86aeb5757a31617666</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RZ400-408</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Scholastic Ashaba</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Childhood trauma is associated with mental health problems among adolescents living with HIV (ALHIV) in sub-Saharan Africa, but little is known about potential moderating factors. Methods: We enrolled 224 ALHIV aged 13–17 years and collected information on childhood trauma, major depressive disorder, and suicidality. We used modified multivariable Poisson regression to estimate the association between the mental health outcome variables and childhood trauma, and to assess for effect modification by social support. Results: Major depressive disorder had a statistically significant association with emotional abuse (adjusted relative risk [ARR] 2.57; 95% CI 1.31–5.04; P = 0.006) and physical abuse (ARR 2.16; 95% CI 1.19–3.89; P = 0.01). The estimated association between any abuse and major depressive disorder was statistically significant among those with a low level of social support (ARR 4.30; 95% CI 1.64–11.25; P = 0.003) but not among those with a high level of social support (ARR 1.30; 95% CI 0.57–2.98; P = 0.52). Suicidality also had a statistically significant association with emotional abuse (ARR 2.03; 95% CI 1.05–3.920; P = 0.03) and physical abuse (ARR 3.17; 95% CI 1.60–6.25.; P = 0.001), but no differences by social support were noted. Limitations: Corporal punishment is used widely in schools and homes as a form of discipline in Uganda; this cultural practice could have biased reporting about physical abuse. Conclusions: Childhood trauma is associated with poor mental health among ALHIV, but its effects may be moderated by social support. More research is needed to develop social support interventions for ALHIV with adverse childhood experiences for improved mental health outcomes.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Adolescents</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Adverse childhood experiences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">HIV</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Mental health</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sub-Saharan Africa</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Uganda</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Mental healing</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Christine E. 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Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda

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