Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study

Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Bennett T Amaechi [verfasserIn] Ramalingam Karthikeyan [verfasserIn] Poornima K Mensinkai [verfasserIn] et al [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2010

Übergeordnetes Werk:	In: Clinical, Cosmetic and Investigational Dentistry - Dove Medical Press, 2009, (2010), default, Seite 93-100
Übergeordnetes Werk:	year:2010 ; number:default ; pages:93-100

Links:	Link aufrufen Link aufrufen Journal toc

Katalog-ID:	DOAJ063610272

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allfields	(DE-627)DOAJ063610272 (DE-599)DOAJbce4ebb12572455e836a1d9d8bd38211 DE-627 ger DE-627 rakwb eng RK1-715 Bennett T Amaechi verfasserin aut Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind Dentistry Ramalingam Karthikeyan verfasserin aut Poornima K Mensinkai verfasserin aut et al verfasserin aut In Clinical, Cosmetic and Investigational Dentistry Dove Medical Press, 2009 (2010), default, Seite 93-100 (DE-627)606031871 (DE-600)2508154-8 11791357 nnns year:2010 number:default pages:93-100 https://doaj.org/article/bce4ebb12572455e836a1d9d8bd38211 kostenfrei http://www.dovepress.com/remineralization-of-eroded-enamel-by-a-naf-rinse-containing-a-novel-ca-a5113 kostenfrei https://doaj.org/toc/1179-1357 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2010 default 93-100
spelling	(DE-627)DOAJ063610272 (DE-599)DOAJbce4ebb12572455e836a1d9d8bd38211 DE-627 ger DE-627 rakwb eng RK1-715 Bennett T Amaechi verfasserin aut Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind Dentistry Ramalingam Karthikeyan verfasserin aut Poornima K Mensinkai verfasserin aut et al verfasserin aut In Clinical, Cosmetic and Investigational Dentistry Dove Medical Press, 2009 (2010), default, Seite 93-100 (DE-627)606031871 (DE-600)2508154-8 11791357 nnns year:2010 number:default pages:93-100 https://doaj.org/article/bce4ebb12572455e836a1d9d8bd38211 kostenfrei http://www.dovepress.com/remineralization-of-eroded-enamel-by-a-naf-rinse-containing-a-novel-ca-a5113 kostenfrei https://doaj.org/toc/1179-1357 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2010 default 93-100
allfields_unstemmed	(DE-627)DOAJ063610272 (DE-599)DOAJbce4ebb12572455e836a1d9d8bd38211 DE-627 ger DE-627 rakwb eng RK1-715 Bennett T Amaechi verfasserin aut Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind Dentistry Ramalingam Karthikeyan verfasserin aut Poornima K Mensinkai verfasserin aut et al verfasserin aut In Clinical, Cosmetic and Investigational Dentistry Dove Medical Press, 2009 (2010), default, Seite 93-100 (DE-627)606031871 (DE-600)2508154-8 11791357 nnns year:2010 number:default pages:93-100 https://doaj.org/article/bce4ebb12572455e836a1d9d8bd38211 kostenfrei http://www.dovepress.com/remineralization-of-eroded-enamel-by-a-naf-rinse-containing-a-novel-ca-a5113 kostenfrei https://doaj.org/toc/1179-1357 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2010 default 93-100
allfieldsGer	(DE-627)DOAJ063610272 (DE-599)DOAJbce4ebb12572455e836a1d9d8bd38211 DE-627 ger DE-627 rakwb eng RK1-715 Bennett T Amaechi verfasserin aut Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind Dentistry Ramalingam Karthikeyan verfasserin aut Poornima K Mensinkai verfasserin aut et al verfasserin aut In Clinical, Cosmetic and Investigational Dentistry Dove Medical Press, 2009 (2010), default, Seite 93-100 (DE-627)606031871 (DE-600)2508154-8 11791357 nnns year:2010 number:default pages:93-100 https://doaj.org/article/bce4ebb12572455e836a1d9d8bd38211 kostenfrei http://www.dovepress.com/remineralization-of-eroded-enamel-by-a-naf-rinse-containing-a-novel-ca-a5113 kostenfrei https://doaj.org/toc/1179-1357 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2010 default 93-100
allfieldsSound	(DE-627)DOAJ063610272 (DE-599)DOAJbce4ebb12572455e836a1d9d8bd38211 DE-627 ger DE-627 rakwb eng RK1-715 Bennett T Amaechi verfasserin aut Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind Dentistry Ramalingam Karthikeyan verfasserin aut Poornima K Mensinkai verfasserin aut et al verfasserin aut In Clinical, Cosmetic and Investigational Dentistry Dove Medical Press, 2009 (2010), default, Seite 93-100 (DE-627)606031871 (DE-600)2508154-8 11791357 nnns year:2010 number:default pages:93-100 https://doaj.org/article/bce4ebb12572455e836a1d9d8bd38211 kostenfrei http://www.dovepress.com/remineralization-of-eroded-enamel-by-a-naf-rinse-containing-a-novel-ca-a5113 kostenfrei https://doaj.org/toc/1179-1357 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2010 default 93-100
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title	Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study
ctrlnum	(DE-627)DOAJ063610272 (DE-599)DOAJbce4ebb12572455e836a1d9d8bd38211
title_full	Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study
author_sort	Bennett T Amaechi
journal	Clinical, Cosmetic and Investigational Dentistry
journalStr	Clinical, Cosmetic and Investigational Dentistry
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author_browse	Bennett T Amaechi Ramalingam Karthikeyan Poornima K Mensinkai et al
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format_se	Elektronische Aufsätze
author-letter	Bennett T Amaechi
author2-role	verfasserin
title_sort	remineralization of eroded enamel by a naf rinse containing a novel calcium phosphate agent in an in situ model: a pilot study
callnumber	RK1-715
title_auth	Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study
abstract	Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind
abstractGer	Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind
abstract_unstemmed	Bennett T Amaechi1, Ramalingam Karthikeyan1, Poornima K Mensinkai1, Kaveh Najibfard1, Allen C Mackey2, Robert L Karlinsey21University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2Indiana Nanotech, Indianapolis, IN, USAPurpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3). Each block was eroded using 1% citric acid (pH = 2.5), with a slice cut from each block to establish baseline lesion parameters (ie, integrated mineral loss ∆Z, and lesion depth LD) using transverse microradiography (TMR). Participants and assigned blocks were randomly divided into three 28-day phases. The blocks were mounted into modified orthodontic brackets and bonded to the buccal surface of one of the subject’s mandibular molars. The appliance remained in the subject’s mouth for 28 days. Prior to each study phase, participants observed a one-week-washout period using a fluoride-free dentifrice. In each phase, participants brushed with the fluoride-free dentifrice for 1 min, followed by one of the following coded treatments: G1: 225 ppm F + 40 ppm TCP-Si-Ur rinse (1 min); G2: 225 ppm F rinse (1 min); G3: no rinse (saliva-only). After each phase, appliances were removed and specimens were analyzed using TMR.Results: TMR data (ie, ∆Z and LD) revealed all three groups significantly remineralized eroded enamel (paired t-tests, P , 0.001). Net mineralization (% change in ∆Z, LD) were as follows (mean (std.dev.): G1: 44.1 (22.6), 30.5 (27.0); G2: 30.0 (7.4), 29.4 (10.5); G3: 23.8 (16.4), 25.7 (15.5). Furthermore, G1 was found to cause significantly more remineralization than G2 (P = 0.039) and G3, (P = 0.002).Conclusion: Mouthrinse containing 225 ppm F plus TCP-Si-Ur provided significantly greater remineralization relative to 225 ppm F only or saliva alone.Keywords: TCP-Si-Ur, fluoride, antierosion, tricalcium phosphate, double-blind
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container_issue	default
title_short	Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study
url	https://doaj.org/article/bce4ebb12572455e836a1d9d8bd38211 http://www.dovepress.com/remineralization-of-eroded-enamel-by-a-naf-rinse-containing-a-novel-ca-a5113 https://doaj.org/toc/1179-1357
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author2	Ramalingam Karthikeyan Poornima K Mensinkai et al
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up_date	2024-07-03T18:37:22.937Z
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