A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)

Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypo...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Fatemeh Choopani [verfasserIn] Ali Choopani [verfasserIn] Mahmood Tavallaei [verfasserIn] Nasrin Kariminejad [verfasserIn] Houri Edalat [verfasserIn]

Format:	E-Artikel
Sprache:	Persisch

Erschienen:	2019

Schlagwörter:	Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer

Übergeordnetes Werk:	In: مجله دانشکده پزشکی اصفهان - Isfahan University of Medical Sciences, 2018, 37(2019), 520, Seite 278-287
Übergeordnetes Werk:	volume:37 ; year:2019 ; number:520 ; pages:278-287

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.22122/jims.v37i520.11114

Katalog-ID:	DOAJ063648806

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ063648806
003	DE-627
005	20230309032047.0
007	cr uuu---uuuuu
008	230228s2019 xx \|\|\|\|\|o 00\| \|\|per c
024	7		\|a 10.22122/jims.v37i520.11114 \|2 doi
035			\|a (DE-627)DOAJ063648806
035			\|a (DE-599)DOAJfcf687329d4b4e609e095c7f68edac96
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a per
050		0	\|a R5-920
100	0		\|a Fatemeh Choopani \|e verfasserin \|4 aut
245	1	2	\|a A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
264		1	\|c 2019
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells.
650		4	\|a Hypoxia
650		4	\|a Hypoxia-inducible factor 1
650		4	\|a Hypoxia-inducible factor 2
650		4	\|a Lung
650		4	\|a Cancer
653		0	\|a Medicine
653		0	\|a R
653		0	\|a Medicine (General)
700	0		\|a Ali Choopani \|e verfasserin \|4 aut
700	0		\|a Mahmood Tavallaei \|e verfasserin \|4 aut
700	0		\|a Nasrin Kariminejad \|e verfasserin \|4 aut
700	0		\|a Houri Edalat \|e verfasserin \|4 aut
773	0	8	\|i In \|t مجله دانشکده پزشکی اصفهان \|d Isfahan University of Medical Sciences, 2018 \|g 37(2019), 520, Seite 278-287 \|w (DE-627)590956124 \|w (DE-600)2476973-3 \|x 1735854X \|7 nnns
773	1	8	\|g volume:37 \|g year:2019 \|g number:520 \|g pages:278-287
856	4	0	\|u https://doi.org/10.22122/jims.v37i520.11114 \|z kostenfrei
856	4	0	\|u https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96 \|z kostenfrei
856	4	0	\|u http://jims.mui.ac.ir/index.php/jims/article/view/11114 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1027-7595 \|y Journal toc \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1735-854X \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 37 \|j 2019 \|e 520 \|h 278-287

Indexfelder

author_variant	f c fc a c ac m t mt n k nk h e he
matchkey_str	article:1735854X:2019----::cmrhnieeiwnniomnaadirevrnetlxgnesnptwymdae
hierarchy_sort_str	2019
callnumber-subject-code	R
publishDate	2019
allfields	10.22122/jims.v37i520.11114 doi (DE-627)DOAJ063648806 (DE-599)DOAJfcf687329d4b4e609e095c7f68edac96 DE-627 ger DE-627 rakwb per R5-920 Fatemeh Choopani verfasserin aut A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs) 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells. Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer Medicine R Medicine (General) Ali Choopani verfasserin aut Mahmood Tavallaei verfasserin aut Nasrin Kariminejad verfasserin aut Houri Edalat verfasserin aut In مجله دانشکده پزشکی اصفهان Isfahan University of Medical Sciences, 2018 37(2019), 520, Seite 278-287 (DE-627)590956124 (DE-600)2476973-3 1735854X nnns volume:37 year:2019 number:520 pages:278-287 https://doi.org/10.22122/jims.v37i520.11114 kostenfrei https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96 kostenfrei http://jims.mui.ac.ir/index.php/jims/article/view/11114 kostenfrei https://doaj.org/toc/1027-7595 Journal toc kostenfrei https://doaj.org/toc/1735-854X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2019 520 278-287
spelling	10.22122/jims.v37i520.11114 doi (DE-627)DOAJ063648806 (DE-599)DOAJfcf687329d4b4e609e095c7f68edac96 DE-627 ger DE-627 rakwb per R5-920 Fatemeh Choopani verfasserin aut A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs) 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells. Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer Medicine R Medicine (General) Ali Choopani verfasserin aut Mahmood Tavallaei verfasserin aut Nasrin Kariminejad verfasserin aut Houri Edalat verfasserin aut In مجله دانشکده پزشکی اصفهان Isfahan University of Medical Sciences, 2018 37(2019), 520, Seite 278-287 (DE-627)590956124 (DE-600)2476973-3 1735854X nnns volume:37 year:2019 number:520 pages:278-287 https://doi.org/10.22122/jims.v37i520.11114 kostenfrei https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96 kostenfrei http://jims.mui.ac.ir/index.php/jims/article/view/11114 kostenfrei https://doaj.org/toc/1027-7595 Journal toc kostenfrei https://doaj.org/toc/1735-854X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2019 520 278-287
allfields_unstemmed	10.22122/jims.v37i520.11114 doi (DE-627)DOAJ063648806 (DE-599)DOAJfcf687329d4b4e609e095c7f68edac96 DE-627 ger DE-627 rakwb per R5-920 Fatemeh Choopani verfasserin aut A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs) 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells. Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer Medicine R Medicine (General) Ali Choopani verfasserin aut Mahmood Tavallaei verfasserin aut Nasrin Kariminejad verfasserin aut Houri Edalat verfasserin aut In مجله دانشکده پزشکی اصفهان Isfahan University of Medical Sciences, 2018 37(2019), 520, Seite 278-287 (DE-627)590956124 (DE-600)2476973-3 1735854X nnns volume:37 year:2019 number:520 pages:278-287 https://doi.org/10.22122/jims.v37i520.11114 kostenfrei https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96 kostenfrei http://jims.mui.ac.ir/index.php/jims/article/view/11114 kostenfrei https://doaj.org/toc/1027-7595 Journal toc kostenfrei https://doaj.org/toc/1735-854X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2019 520 278-287
allfieldsGer	10.22122/jims.v37i520.11114 doi (DE-627)DOAJ063648806 (DE-599)DOAJfcf687329d4b4e609e095c7f68edac96 DE-627 ger DE-627 rakwb per R5-920 Fatemeh Choopani verfasserin aut A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs) 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells. Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer Medicine R Medicine (General) Ali Choopani verfasserin aut Mahmood Tavallaei verfasserin aut Nasrin Kariminejad verfasserin aut Houri Edalat verfasserin aut In مجله دانشکده پزشکی اصفهان Isfahan University of Medical Sciences, 2018 37(2019), 520, Seite 278-287 (DE-627)590956124 (DE-600)2476973-3 1735854X nnns volume:37 year:2019 number:520 pages:278-287 https://doi.org/10.22122/jims.v37i520.11114 kostenfrei https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96 kostenfrei http://jims.mui.ac.ir/index.php/jims/article/view/11114 kostenfrei https://doaj.org/toc/1027-7595 Journal toc kostenfrei https://doaj.org/toc/1735-854X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2019 520 278-287
allfieldsSound	10.22122/jims.v37i520.11114 doi (DE-627)DOAJ063648806 (DE-599)DOAJfcf687329d4b4e609e095c7f68edac96 DE-627 ger DE-627 rakwb per R5-920 Fatemeh Choopani verfasserin aut A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs) 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells. Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer Medicine R Medicine (General) Ali Choopani verfasserin aut Mahmood Tavallaei verfasserin aut Nasrin Kariminejad verfasserin aut Houri Edalat verfasserin aut In مجله دانشکده پزشکی اصفهان Isfahan University of Medical Sciences, 2018 37(2019), 520, Seite 278-287 (DE-627)590956124 (DE-600)2476973-3 1735854X nnns volume:37 year:2019 number:520 pages:278-287 https://doi.org/10.22122/jims.v37i520.11114 kostenfrei https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96 kostenfrei http://jims.mui.ac.ir/index.php/jims/article/view/11114 kostenfrei https://doaj.org/toc/1027-7595 Journal toc kostenfrei https://doaj.org/toc/1735-854X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2019 520 278-287
language	Persian
source	In مجله دانشکده پزشکی اصفهان 37(2019), 520, Seite 278-287 volume:37 year:2019 number:520 pages:278-287
sourceStr	In مجله دانشکده پزشکی اصفهان 37(2019), 520, Seite 278-287 volume:37 year:2019 number:520 pages:278-287
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer Medicine R Medicine (General)
isfreeaccess_bool	true
container_title	مجله دانشکده پزشکی اصفهان
authorswithroles_txt_mv	Fatemeh Choopani @@aut@@ Ali Choopani @@aut@@ Mahmood Tavallaei @@aut@@ Nasrin Kariminejad @@aut@@ Houri Edalat @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
hierarchy_top_id	590956124
id	DOAJ063648806
language_de	persisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ063648806</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230309032047.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2019 xx \|\|\|\|\|o 00\| \|\|per c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.22122/jims.v37i520.11114</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ063648806</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJfcf687329d4b4e609e095c7f68edac96</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">per</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">R5-920</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Fatemeh Choopani</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="2"><subfield code="a">A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypoxia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypoxia-inducible factor 1</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypoxia-inducible factor 2</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Lung</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine (General)</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ali Choopani</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mahmood Tavallaei</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nasrin Kariminejad</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Houri Edalat</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">مجله دانشکده پزشکی اصفهان</subfield><subfield code="d">Isfahan University of Medical Sciences, 2018</subfield><subfield code="g">37(2019), 520, Seite 278-287</subfield><subfield code="w">(DE-627)590956124</subfield><subfield code="w">(DE-600)2476973-3</subfield><subfield code="x">1735854X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:37</subfield><subfield code="g">year:2019</subfield><subfield code="g">number:520</subfield><subfield code="g">pages:278-287</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.22122/jims.v37i520.11114</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://jims.mui.ac.ir/index.php/jims/article/view/11114</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1027-7595</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1735-854X</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">37</subfield><subfield code="j">2019</subfield><subfield code="e">520</subfield><subfield code="h">278-287</subfield></datafield></record></collection>
callnumber-first	R - Medicine
author	Fatemeh Choopani
spellingShingle	Fatemeh Choopani misc R5-920 misc Hypoxia misc Hypoxia-inducible factor 1 misc Hypoxia-inducible factor 2 misc Lung misc Cancer misc Medicine misc R misc Medicine (General) A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
authorStr	Fatemeh Choopani
ppnlink_with_tag_str_mv	@@773@@(DE-627)590956124
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	R5-920
illustrated	Not Illustrated
issn	1735854X
topic_title	R5-920 A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs) Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 2 Lung Cancer
topic	misc R5-920 misc Hypoxia misc Hypoxia-inducible factor 1 misc Hypoxia-inducible factor 2 misc Lung misc Cancer misc Medicine misc R misc Medicine (General)
topic_unstemmed	misc R5-920 misc Hypoxia misc Hypoxia-inducible factor 1 misc Hypoxia-inducible factor 2 misc Lung misc Cancer misc Medicine misc R misc Medicine (General)
topic_browse	misc R5-920 misc Hypoxia misc Hypoxia-inducible factor 1 misc Hypoxia-inducible factor 2 misc Lung misc Cancer misc Medicine misc R misc Medicine (General)
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	مجله دانشکده پزشکی اصفهان
hierarchy_parent_id	590956124
hierarchy_top_title	مجله دانشکده پزشکی اصفهان
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)590956124 (DE-600)2476973-3
title	A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
ctrlnum	(DE-627)DOAJ063648806 (DE-599)DOAJfcf687329d4b4e609e095c7f68edac96
title_full	A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
author_sort	Fatemeh Choopani
journal	مجله دانشکده پزشکی اصفهان
journalStr	مجله دانشکده پزشکی اصفهان
callnumber-first-code	R
lang_code	per
isOA_bool	true
recordtype	marc
publishDateSort	2019
contenttype_str_mv	txt
container_start_page	278
author_browse	Fatemeh Choopani Ali Choopani Mahmood Tavallaei Nasrin Kariminejad Houri Edalat
container_volume	37
class	R5-920
format_se	Elektronische Aufsätze
author-letter	Fatemeh Choopani
doi_str_mv	10.22122/jims.v37i520.11114
author2-role	verfasserin
title_sort	comprehensive review on environmental and microenvironmental oxygen sensing pathways mediated by hypoxia-inducible factors (hifs)
callnumber	R5-920
title_auth	A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
abstract	Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells.
abstractGer	Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells.
abstract_unstemmed	Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	520
title_short	A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
url	https://doi.org/10.22122/jims.v37i520.11114 https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96 http://jims.mui.ac.ir/index.php/jims/article/view/11114 https://doaj.org/toc/1027-7595 https://doaj.org/toc/1735-854X
remote_bool	true
author2	Ali Choopani Mahmood Tavallaei Nasrin Kariminejad Houri Edalat
author2Str	Ali Choopani Mahmood Tavallaei Nasrin Kariminejad Houri Edalat
ppnlink	590956124
callnumber-subject	R - General Medicine
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.22122/jims.v37i520.11114
callnumber-a	R5-920
up_date	2024-07-03T18:49:31.494Z
_version_	1803584873692135424
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ063648806</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230309032047.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2019 xx \|\|\|\|\|o 00\| \|\|per c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.22122/jims.v37i520.11114</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ063648806</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJfcf687329d4b4e609e095c7f68edac96</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">per</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">R5-920</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Fatemeh Choopani</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="2"><subfield code="a">A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Oxygen deficiency, referred to as hypoxia, can be divided into two categories of environmental (exogenous) which is sensitized by respiratory cells, and microenvironmental (endogenous) responses by other cells in the body, like cancer cells. Cell responses to oxygen fluctuations are mediated by hypoxia-inducible factors (HIFs). Lung is known as the first organ that encounters the exogenous and environmental oxygen after breathing. However, data are limited for HIF respiratory pathways of environmental oxygen sensing inside the lung cells. Thus, we evaluated the role of both HIF-1 and HIF-2 isoforms in environmental hypoxia sensation by pulmonary vascular and bronchial cells. Then, we introduced the role of HIFs in microenvironmental and endogenous oxygen sensation in tissues and cells other than respiratory cells as well as all of involved molecular mechanisms in those non-lung cells and tissues. Next, a detailed emphasize was put on the strict role of HIF molecule in tumor cells and cancer stem cells.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypoxia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypoxia-inducible factor 1</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypoxia-inducible factor 2</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Lung</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine (General)</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ali Choopani</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mahmood Tavallaei</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nasrin Kariminejad</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Houri Edalat</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">مجله دانشکده پزشکی اصفهان</subfield><subfield code="d">Isfahan University of Medical Sciences, 2018</subfield><subfield code="g">37(2019), 520, Seite 278-287</subfield><subfield code="w">(DE-627)590956124</subfield><subfield code="w">(DE-600)2476973-3</subfield><subfield code="x">1735854X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:37</subfield><subfield code="g">year:2019</subfield><subfield code="g">number:520</subfield><subfield code="g">pages:278-287</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.22122/jims.v37i520.11114</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/fcf687329d4b4e609e095c7f68edac96</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://jims.mui.ac.ir/index.php/jims/article/view/11114</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1027-7595</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1735-854X</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">37</subfield><subfield code="j">2019</subfield><subfield code="e">520</subfield><subfield code="h">278-287</subfield></datafield></record></collection>
score	7.400983

Nicht das Richtige dabei?

Schreiben Sie uns!

A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?