Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways

Animals can adapt their body size to changing environments (e.g., temperature) but the underlying molecular mechanisms are unknown. Here, the authors show that temperature and the genetic factors insulin-like peptide receptor and FoxO determine size in Hydra via the conserved pathways (Wnt/TGF-β).

Gespeichert in:

Autor*in:	Benedikt M. Mortzfeld [verfasserIn] Jan Taubenheim [verfasserIn] Alexander V. Klimovich [verfasserIn] Sebastian Fraune [verfasserIn] Philip Rosenstiel [verfasserIn] Thomas C. G. Bosch [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 10(2019), 1, Seite 13
Übergeordnetes Werk:	volume:10 ; year:2019 ; number:1 ; pages:13

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-019-11136-6

Katalog-ID:	DOAJ066620872

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author	Benedikt M. Mortzfeld
spellingShingle	Benedikt M. Mortzfeld misc Science misc Q Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
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topic_title	Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
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title	Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
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title_full	Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
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author_browse	Benedikt M. Mortzfeld Jan Taubenheim Alexander V. Klimovich Sebastian Fraune Philip Rosenstiel Thomas C. G. Bosch
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title_sort	temperature and insulin signaling regulate body size in hydra by the wnt and tgf-beta pathways
title_auth	Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
abstract	Animals can adapt their body size to changing environments (e.g., temperature) but the underlying molecular mechanisms are unknown. Here, the authors show that temperature and the genetic factors insulin-like peptide receptor and FoxO determine size in Hydra via the conserved pathways (Wnt/TGF-β).
abstractGer	Animals can adapt their body size to changing environments (e.g., temperature) but the underlying molecular mechanisms are unknown. Here, the authors show that temperature and the genetic factors insulin-like peptide receptor and FoxO determine size in Hydra via the conserved pathways (Wnt/TGF-β).
abstract_unstemmed	Animals can adapt their body size to changing environments (e.g., temperature) but the underlying molecular mechanisms are unknown. Here, the authors show that temperature and the genetic factors insulin-like peptide receptor and FoxO determine size in Hydra via the conserved pathways (Wnt/TGF-β).
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title_short	Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
url	https://doi.org/10.1038/s41467-019-11136-6 https://doaj.org/article/a54475c745684a26b3831a7fe24847f4 https://doaj.org/toc/2041-1723
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