Multifocal Electroretinography in Diabetic Patients without Retinopathy

INTRODUCTION[|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Özgür Balta [verfasserIn] Gulten Sungur [verfasserIn] Mehmet Yakın [verfasserIn] Nurten Unlu [verfasserIn] Oyku Bezen Balta [verfasserIn] Eyup Ozcan [verfasserIn] Firdevs Ornek [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	multifocal electroretinography diabetes diabetic retinopathy

Übergeordnetes Werk:	In: Beyoglu Eye Journal - KARE Publishing, 2020, 3(2018), 3, Seite 109-115
Übergeordnetes Werk:	volume:3 ; year:2018 ; number:3 ; pages:109-115

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.14744/bej.2018.29491

Katalog-ID:	DOAJ066889065

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520			\|a INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤]
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author_variant	ö b öb g s gs m y my n u nu o b b obb e o eo f o fo
matchkey_str	article:25870394:2018----::utfcllcrrtngahidaeiptetw
hierarchy_sort_str	2018
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allfields	10.14744/bej.2018.29491 doi (DE-627)DOAJ066889065 (DE-599)DOAJ4f3c06a9d14841a7b697eed4cbf7ac89 DE-627 ger DE-627 rakwb eng RE1-994 Özgür Balta verfasserin aut Multifocal Electroretinography in Diabetic Patients without Retinopathy 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤] multifocal electroretinography diabetes diabetic retinopathy Ophthalmology Gulten Sungur verfasserin aut Mehmet Yakın verfasserin aut Nurten Unlu verfasserin aut Oyku Bezen Balta verfasserin aut Eyup Ozcan verfasserin aut Firdevs Ornek verfasserin aut In Beyoglu Eye Journal KARE Publishing, 2020 3(2018), 3, Seite 109-115 (DE-627)1725122200 25870394 nnns volume:3 year:2018 number:3 pages:109-115 https://doi.org/10.14744/bej.2018.29491 kostenfrei https://doaj.org/article/4f3c06a9d14841a7b697eed4cbf7ac89 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-29491 kostenfrei https://doaj.org/toc/2587-0394 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2018 3 109-115
spelling	10.14744/bej.2018.29491 doi (DE-627)DOAJ066889065 (DE-599)DOAJ4f3c06a9d14841a7b697eed4cbf7ac89 DE-627 ger DE-627 rakwb eng RE1-994 Özgür Balta verfasserin aut Multifocal Electroretinography in Diabetic Patients without Retinopathy 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤] multifocal electroretinography diabetes diabetic retinopathy Ophthalmology Gulten Sungur verfasserin aut Mehmet Yakın verfasserin aut Nurten Unlu verfasserin aut Oyku Bezen Balta verfasserin aut Eyup Ozcan verfasserin aut Firdevs Ornek verfasserin aut In Beyoglu Eye Journal KARE Publishing, 2020 3(2018), 3, Seite 109-115 (DE-627)1725122200 25870394 nnns volume:3 year:2018 number:3 pages:109-115 https://doi.org/10.14744/bej.2018.29491 kostenfrei https://doaj.org/article/4f3c06a9d14841a7b697eed4cbf7ac89 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-29491 kostenfrei https://doaj.org/toc/2587-0394 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2018 3 109-115
allfields_unstemmed	10.14744/bej.2018.29491 doi (DE-627)DOAJ066889065 (DE-599)DOAJ4f3c06a9d14841a7b697eed4cbf7ac89 DE-627 ger DE-627 rakwb eng RE1-994 Özgür Balta verfasserin aut Multifocal Electroretinography in Diabetic Patients without Retinopathy 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤] multifocal electroretinography diabetes diabetic retinopathy Ophthalmology Gulten Sungur verfasserin aut Mehmet Yakın verfasserin aut Nurten Unlu verfasserin aut Oyku Bezen Balta verfasserin aut Eyup Ozcan verfasserin aut Firdevs Ornek verfasserin aut In Beyoglu Eye Journal KARE Publishing, 2020 3(2018), 3, Seite 109-115 (DE-627)1725122200 25870394 nnns volume:3 year:2018 number:3 pages:109-115 https://doi.org/10.14744/bej.2018.29491 kostenfrei https://doaj.org/article/4f3c06a9d14841a7b697eed4cbf7ac89 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-29491 kostenfrei https://doaj.org/toc/2587-0394 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2018 3 109-115
allfieldsGer	10.14744/bej.2018.29491 doi (DE-627)DOAJ066889065 (DE-599)DOAJ4f3c06a9d14841a7b697eed4cbf7ac89 DE-627 ger DE-627 rakwb eng RE1-994 Özgür Balta verfasserin aut Multifocal Electroretinography in Diabetic Patients without Retinopathy 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤] multifocal electroretinography diabetes diabetic retinopathy Ophthalmology Gulten Sungur verfasserin aut Mehmet Yakın verfasserin aut Nurten Unlu verfasserin aut Oyku Bezen Balta verfasserin aut Eyup Ozcan verfasserin aut Firdevs Ornek verfasserin aut In Beyoglu Eye Journal KARE Publishing, 2020 3(2018), 3, Seite 109-115 (DE-627)1725122200 25870394 nnns volume:3 year:2018 number:3 pages:109-115 https://doi.org/10.14744/bej.2018.29491 kostenfrei https://doaj.org/article/4f3c06a9d14841a7b697eed4cbf7ac89 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-29491 kostenfrei https://doaj.org/toc/2587-0394 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2018 3 109-115
allfieldsSound	10.14744/bej.2018.29491 doi (DE-627)DOAJ066889065 (DE-599)DOAJ4f3c06a9d14841a7b697eed4cbf7ac89 DE-627 ger DE-627 rakwb eng RE1-994 Özgür Balta verfasserin aut Multifocal Electroretinography in Diabetic Patients without Retinopathy 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤] multifocal electroretinography diabetes diabetic retinopathy Ophthalmology Gulten Sungur verfasserin aut Mehmet Yakın verfasserin aut Nurten Unlu verfasserin aut Oyku Bezen Balta verfasserin aut Eyup Ozcan verfasserin aut Firdevs Ornek verfasserin aut In Beyoglu Eye Journal KARE Publishing, 2020 3(2018), 3, Seite 109-115 (DE-627)1725122200 25870394 nnns volume:3 year:2018 number:3 pages:109-115 https://doi.org/10.14744/bej.2018.29491 kostenfrei https://doaj.org/article/4f3c06a9d14841a7b697eed4cbf7ac89 kostenfrei https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-29491 kostenfrei https://doaj.org/toc/2587-0394 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2018 3 109-115
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Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. 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callnumber-first	R - Medicine
author	Özgür Balta
spellingShingle	Özgür Balta misc RE1-994 misc multifocal electroretinography misc diabetes misc diabetic retinopathy misc Ophthalmology Multifocal Electroretinography in Diabetic Patients without Retinopathy
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topic_title	RE1-994 Multifocal Electroretinography in Diabetic Patients without Retinopathy multifocal electroretinography diabetes diabetic retinopathy
topic	misc RE1-994 misc multifocal electroretinography misc diabetes misc diabetic retinopathy misc Ophthalmology
topic_unstemmed	misc RE1-994 misc multifocal electroretinography misc diabetes misc diabetic retinopathy misc Ophthalmology
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title	Multifocal Electroretinography in Diabetic Patients without Retinopathy
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title_full	Multifocal Electroretinography in Diabetic Patients without Retinopathy
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author_browse	Özgür Balta Gulten Sungur Mehmet Yakın Nurten Unlu Oyku Bezen Balta Eyup Ozcan Firdevs Ornek
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doi_str_mv	10.14744/bej.2018.29491
author2-role	verfasserin
title_sort	multifocal electroretinography in diabetic patients without retinopathy
callnumber	RE1-994
title_auth	Multifocal Electroretinography in Diabetic Patients without Retinopathy
abstract	INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤]
abstractGer	INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤]
abstract_unstemmed	INTRODUCTION[\|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[\|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤]
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title_short	Multifocal Electroretinography in Diabetic Patients without Retinopathy
url	https://doi.org/10.14744/bej.2018.29491 https://doaj.org/article/4f3c06a9d14841a7b697eed4cbf7ac89 https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-29491 https://doaj.org/toc/2587-0394
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author2	Gulten Sungur Mehmet Yakın Nurten Unlu Oyku Bezen Balta Eyup Ozcan Firdevs Ornek
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up_date	2024-07-03T22:31:44.691Z
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Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[\|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[\|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. 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Multifocal Electroretinography in Diabetic Patients without Retinopathy

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