A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors

False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.

Gespeichert in:

Autor*in:	Rabia Mateen [verfasserIn] M. Monsur Ali [verfasserIn] Todd Hoare [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 9(2018), 1, Seite 9
Übergeordnetes Werk:	volume:9 ; year:2018 ; number:1 ; pages:9

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-018-02956-z

Katalog-ID:	DOAJ067745164

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title	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
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title_sort	printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
title_auth	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
abstract	False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.
abstractGer	False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.
abstract_unstemmed	False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.
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title_short	A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors
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