Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference
Human reference genomes are typically constructed from few individuals, and are biased towards European and African genomes. Here, the authors assemble three Japanese genomes to create a population-specific reference genome. They then demonstrate improved variant calling from exome sequencing with t...
Ausführliche Beschreibung
Autor*in: |
Jun Takayama [verfasserIn] Shu Tadaka [verfasserIn] Kenji Yano [verfasserIn] Fumiki Katsuoka [verfasserIn] Chinatsu Gocho [verfasserIn] Takamitsu Funayama [verfasserIn] Satoshi Makino [verfasserIn] Yasunobu Okamura [verfasserIn] Atsuo Kikuchi [verfasserIn] Sachiyo Sugimoto [verfasserIn] Junko Kawashima [verfasserIn] Akihito Otsuki [verfasserIn] Mika Sakurai-Yageta [verfasserIn] Jun Yasuda [verfasserIn] Shigeo Kure [verfasserIn] Kengo Kinoshita [verfasserIn] Masayuki Yamamoto [verfasserIn] Gen Tamiya [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Übergeordnetes Werk: |
In: Nature Communications - Nature Portfolio, 2016, 12(2021), 1, Seite 14 |
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Übergeordnetes Werk: |
volume:12 ; year:2021 ; number:1 ; pages:14 |
Links: |
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DOI / URN: |
10.1038/s41467-020-20146-8 |
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Katalog-ID: |
DOAJ067905919 |
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Jun Takayama @@aut@@ Shu Tadaka @@aut@@ Kenji Yano @@aut@@ Fumiki Katsuoka @@aut@@ Chinatsu Gocho @@aut@@ Takamitsu Funayama @@aut@@ Satoshi Makino @@aut@@ Yasunobu Okamura @@aut@@ Atsuo Kikuchi @@aut@@ Sachiyo Sugimoto @@aut@@ Junko Kawashima @@aut@@ Akihito Otsuki @@aut@@ Mika Sakurai-Yageta @@aut@@ Jun Yasuda @@aut@@ Shigeo Kure @@aut@@ Kengo Kinoshita @@aut@@ Masayuki Yamamoto @@aut@@ Gen Tamiya @@aut@@ |
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Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference |
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Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference |
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Human reference genomes are typically constructed from few individuals, and are biased towards European and African genomes. Here, the authors assemble three Japanese genomes to create a population-specific reference genome. They then demonstrate improved variant calling from exome sequencing with this reference genome. |
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Human reference genomes are typically constructed from few individuals, and are biased towards European and African genomes. Here, the authors assemble three Japanese genomes to create a population-specific reference genome. They then demonstrate improved variant calling from exome sequencing with this reference genome. |
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Human reference genomes are typically constructed from few individuals, and are biased towards European and African genomes. Here, the authors assemble three Japanese genomes to create a population-specific reference genome. They then demonstrate improved variant calling from exome sequencing with this reference genome. |
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Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference |
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