A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease

Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent P...
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Gespeichert in:

Autor*in:	Duncan NA [verfasserIn] Kronenberger WG [verfasserIn] Hampton KC [verfasserIn] Bloom EM [verfasserIn] Rampersad AG [verfasserIn] Roberson CP [verfasserIn] Shapiro AD [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	sickle cell disease penicillin prophylaxis antibiotic prophylaxis prophylaxis adherence

Übergeordnetes Werk:	In: Patient Preference and Adherence - Dove Medical Press, 2008, (2016), Issue 1, Seite 983-992
Übergeordnetes Werk:	year:2016 ; number:Issue 1 ; pages:983-992

Links:	Link aufrufen Link aufrufen Journal toc

Katalog-ID:	DOAJ06814542X

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520			\|a Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance
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allfields	(DE-627)DOAJ06814542X (DE-599)DOAJad3df6c4668049d5af0e02c5d159a84b DE-627 ger DE-627 rakwb eng R5-920 Duncan NA verfasserin aut A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance sickle cell disease penicillin prophylaxis antibiotic prophylaxis prophylaxis adherence Medicine (General) Kronenberger WG verfasserin aut Hampton KC verfasserin aut Bloom EM verfasserin aut Rampersad AG verfasserin aut Roberson CP verfasserin aut Shapiro AD verfasserin aut In Patient Preference and Adherence Dove Medical Press, 2008 (2016), Issue 1, Seite 983-992 (DE-627)582018145 (DE-600)2455848-5 1177889X nnns year:2016 number:Issue 1 pages:983-992 https://doaj.org/article/ad3df6c4668049d5af0e02c5d159a84b kostenfrei https://www.dovepress.com/a-validated-measure-of-adherence-to-antibiotic-prophylaxis-in-children-peer-reviewed-article-PPA kostenfrei https://doaj.org/toc/1177-889X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2016 Issue 1 983-992
spelling	(DE-627)DOAJ06814542X (DE-599)DOAJad3df6c4668049d5af0e02c5d159a84b DE-627 ger DE-627 rakwb eng R5-920 Duncan NA verfasserin aut A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance sickle cell disease penicillin prophylaxis antibiotic prophylaxis prophylaxis adherence Medicine (General) Kronenberger WG verfasserin aut Hampton KC verfasserin aut Bloom EM verfasserin aut Rampersad AG verfasserin aut Roberson CP verfasserin aut Shapiro AD verfasserin aut In Patient Preference and Adherence Dove Medical Press, 2008 (2016), Issue 1, Seite 983-992 (DE-627)582018145 (DE-600)2455848-5 1177889X nnns year:2016 number:Issue 1 pages:983-992 https://doaj.org/article/ad3df6c4668049d5af0e02c5d159a84b kostenfrei https://www.dovepress.com/a-validated-measure-of-adherence-to-antibiotic-prophylaxis-in-children-peer-reviewed-article-PPA kostenfrei https://doaj.org/toc/1177-889X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2016 Issue 1 983-992
allfields_unstemmed	(DE-627)DOAJ06814542X (DE-599)DOAJad3df6c4668049d5af0e02c5d159a84b DE-627 ger DE-627 rakwb eng R5-920 Duncan NA verfasserin aut A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance sickle cell disease penicillin prophylaxis antibiotic prophylaxis prophylaxis adherence Medicine (General) Kronenberger WG verfasserin aut Hampton KC verfasserin aut Bloom EM verfasserin aut Rampersad AG verfasserin aut Roberson CP verfasserin aut Shapiro AD verfasserin aut In Patient Preference and Adherence Dove Medical Press, 2008 (2016), Issue 1, Seite 983-992 (DE-627)582018145 (DE-600)2455848-5 1177889X nnns year:2016 number:Issue 1 pages:983-992 https://doaj.org/article/ad3df6c4668049d5af0e02c5d159a84b kostenfrei https://www.dovepress.com/a-validated-measure-of-adherence-to-antibiotic-prophylaxis-in-children-peer-reviewed-article-PPA kostenfrei https://doaj.org/toc/1177-889X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2016 Issue 1 983-992
allfieldsGer	(DE-627)DOAJ06814542X (DE-599)DOAJad3df6c4668049d5af0e02c5d159a84b DE-627 ger DE-627 rakwb eng R5-920 Duncan NA verfasserin aut A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance sickle cell disease penicillin prophylaxis antibiotic prophylaxis prophylaxis adherence Medicine (General) Kronenberger WG verfasserin aut Hampton KC verfasserin aut Bloom EM verfasserin aut Rampersad AG verfasserin aut Roberson CP verfasserin aut Shapiro AD verfasserin aut In Patient Preference and Adherence Dove Medical Press, 2008 (2016), Issue 1, Seite 983-992 (DE-627)582018145 (DE-600)2455848-5 1177889X nnns year:2016 number:Issue 1 pages:983-992 https://doaj.org/article/ad3df6c4668049d5af0e02c5d159a84b kostenfrei https://www.dovepress.com/a-validated-measure-of-adherence-to-antibiotic-prophylaxis-in-children-peer-reviewed-article-PPA kostenfrei https://doaj.org/toc/1177-889X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2016 Issue 1 983-992
allfieldsSound	(DE-627)DOAJ06814542X (DE-599)DOAJad3df6c4668049d5af0e02c5d159a84b DE-627 ger DE-627 rakwb eng R5-920 Duncan NA verfasserin aut A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance sickle cell disease penicillin prophylaxis antibiotic prophylaxis prophylaxis adherence Medicine (General) Kronenberger WG verfasserin aut Hampton KC verfasserin aut Bloom EM verfasserin aut Rampersad AG verfasserin aut Roberson CP verfasserin aut Shapiro AD verfasserin aut In Patient Preference and Adherence Dove Medical Press, 2008 (2016), Issue 1, Seite 983-992 (DE-627)582018145 (DE-600)2455848-5 1177889X nnns year:2016 number:Issue 1 pages:983-992 https://doaj.org/article/ad3df6c4668049d5af0e02c5d159a84b kostenfrei https://www.dovepress.com/a-validated-measure-of-adherence-to-antibiotic-prophylaxis-in-children-peer-reviewed-article-PPA kostenfrei https://doaj.org/toc/1177-889X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2016 Issue 1 983-992
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topic_title	R5-920 A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease sickle cell disease penicillin prophylaxis antibiotic prophylaxis prophylaxis adherence
topic	misc R5-920 misc sickle cell disease misc penicillin prophylaxis misc antibiotic prophylaxis misc prophylaxis misc adherence misc Medicine (General)
topic_unstemmed	misc R5-920 misc sickle cell disease misc penicillin prophylaxis misc antibiotic prophylaxis misc prophylaxis misc adherence misc Medicine (General)
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title	A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease
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title_full	A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease
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title_sort	validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease
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title_auth	A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease
abstract	Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance
abstractGer	Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance
abstract_unstemmed	Natalie A Duncan,1 William G Kronenberger,2 Kisha C Hampton,1 Ellen M Bloom,1 Angeli G Rampersad,1 Christopher P Roberson,1 Amy D Shapiro11Department of Hematology, Indiana Hemophilia and Thrombosis Center, 2Department of Psychiatry, Indiana University School of Medicine Riley and Child Adolescent Psychiatry Clinic, Indianapolis, IN, USABackground: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation.Methods: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures.Results: Internal consistency was very good to excellent for the total SCAALE (a=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales.Conclusion: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research. Keywords: penicillin prophylaxis, SCAALE, newborn screening program, Sickle SAFE Program, hemoglobinopathy, compliance
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title_short	A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease
url	https://doaj.org/article/ad3df6c4668049d5af0e02c5d159a84b https://www.dovepress.com/a-validated-measure-of-adherence-to-antibiotic-prophylaxis-in-children-peer-reviewed-article-PPA https://doaj.org/toc/1177-889X
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up_date	2024-07-03T16:07:46.271Z
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A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease

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