Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application

Hydroxyapatite (HA) was coated onto the surface of commercially pure titanium grade 4 (a material generally used for implant application) by a dip coating method using HA sol. Hydroxyapatite sol was synthesized via sol−gel using Ca(NO<sub<3</sub<)<sub<2</sub<∙4H<sub<2&l...
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Gespeichert in:

Autor*in:	Michelina Catauro [verfasserIn] Federico Barrino [verfasserIn] Ignazio Blanco [verfasserIn] Simona Piccolella [verfasserIn] Severina Pacifico [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	sol–gel synthesis hydroxyapatite titanium substrate coating biocompatibility

Übergeordnetes Werk:	In: Coatings - MDPI AG, 2012, 10(2020), 3, p 203
Übergeordnetes Werk:	volume:10 ; year:2020 ; number:3, p 203

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/coatings10030203

Katalog-ID:	DOAJ068839766

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language	English
source	In Coatings 10(2020), 3, p 203 volume:10 year:2020 number:3, p 203
sourceStr	In Coatings 10(2020), 3, p 203 volume:10 year:2020 number:3, p 203
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topic_facet	sol–gel synthesis hydroxyapatite titanium substrate coating biocompatibility Engineering (General). Civil engineering (General)
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container_title	Coatings
authorswithroles_txt_mv	Michelina Catauro @@aut@@ Federico Barrino @@aut@@ Ignazio Blanco @@aut@@ Simona Piccolella @@aut@@ Severina Pacifico @@aut@@
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callnumber-first	T - Technology
author	Michelina Catauro
spellingShingle	Michelina Catauro misc TA1-2040 misc sol–gel synthesis misc hydroxyapatite misc titanium substrate coating misc biocompatibility misc Engineering (General). Civil engineering (General) Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application
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topic_title	TA1-2040 Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application sol–gel synthesis hydroxyapatite titanium substrate coating biocompatibility
topic	misc TA1-2040 misc sol–gel synthesis misc hydroxyapatite misc titanium substrate coating misc biocompatibility misc Engineering (General). Civil engineering (General)
topic_unstemmed	misc TA1-2040 misc sol–gel synthesis misc hydroxyapatite misc titanium substrate coating misc biocompatibility misc Engineering (General). Civil engineering (General)
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title	Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application
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title_full	Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application
author_sort	Michelina Catauro
journal	Coatings
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author_browse	Michelina Catauro Federico Barrino Ignazio Blanco Simona Piccolella Severina Pacifico
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title_sort	use of the sol–gel method for the preparation of coatings of titanium substrates with hydroxyapatite for biomedical application
callnumber	TA1-2040
title_auth	Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application
abstract	Hydroxyapatite (HA) was coated onto the surface of commercially pure titanium grade 4 (a material generally used for implant application) by a dip coating method using HA sol. Hydroxyapatite sol was synthesized via sol−gel using Ca(NO<sub<3</sub<)<sub<2</sub<∙4H<sub<2</sub<O and P<sub<2</sub<O<sub<5</sub< as precursors. The surface of the HA coating was homogeneous, as determined by scanning electron microscopy (SEM), attenuated total reflectance Fourier transform infrared (ATR-FTIR), and X-ray diffraction (XRD), which allowed the materials to be characterized. The bioactivity of the synthesized materials and their efficiency for use as future bone implants was confirmed by observing the formation of a layer of hydroxyapatite on the surface of the samples soaked in a fluid simulating the composition of human blood plasma. To verify the biocompatibility of the obtained biomaterial, fibroblasts were grown on a glass surface and were tested for viability after 24 h. The results of the WST-8 analysis suggest that the HA systems, prepared by the sol−gel method, are most suitable for modifying the surface of titanium implants and improving their biocompatibility.
abstractGer	Hydroxyapatite (HA) was coated onto the surface of commercially pure titanium grade 4 (a material generally used for implant application) by a dip coating method using HA sol. Hydroxyapatite sol was synthesized via sol−gel using Ca(NO<sub<3</sub<)<sub<2</sub<∙4H<sub<2</sub<O and P<sub<2</sub<O<sub<5</sub< as precursors. The surface of the HA coating was homogeneous, as determined by scanning electron microscopy (SEM), attenuated total reflectance Fourier transform infrared (ATR-FTIR), and X-ray diffraction (XRD), which allowed the materials to be characterized. The bioactivity of the synthesized materials and their efficiency for use as future bone implants was confirmed by observing the formation of a layer of hydroxyapatite on the surface of the samples soaked in a fluid simulating the composition of human blood plasma. To verify the biocompatibility of the obtained biomaterial, fibroblasts were grown on a glass surface and were tested for viability after 24 h. The results of the WST-8 analysis suggest that the HA systems, prepared by the sol−gel method, are most suitable for modifying the surface of titanium implants and improving their biocompatibility.
abstract_unstemmed	Hydroxyapatite (HA) was coated onto the surface of commercially pure titanium grade 4 (a material generally used for implant application) by a dip coating method using HA sol. Hydroxyapatite sol was synthesized via sol−gel using Ca(NO<sub<3</sub<)<sub<2</sub<∙4H<sub<2</sub<O and P<sub<2</sub<O<sub<5</sub< as precursors. The surface of the HA coating was homogeneous, as determined by scanning electron microscopy (SEM), attenuated total reflectance Fourier transform infrared (ATR-FTIR), and X-ray diffraction (XRD), which allowed the materials to be characterized. The bioactivity of the synthesized materials and their efficiency for use as future bone implants was confirmed by observing the formation of a layer of hydroxyapatite on the surface of the samples soaked in a fluid simulating the composition of human blood plasma. To verify the biocompatibility of the obtained biomaterial, fibroblasts were grown on a glass surface and were tested for viability after 24 h. The results of the WST-8 analysis suggest that the HA systems, prepared by the sol−gel method, are most suitable for modifying the surface of titanium implants and improving their biocompatibility.
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container_issue	3, p 203
title_short	Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application
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Use of the Sol–Gel Method for the Preparation of Coatings of Titanium Substrates with Hydroxyapatite for Biomedical Application

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