Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios

Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Nora Bruns [verfasserIn] Ann-Christin Stähling [verfasserIn] Sandra Greve [verfasserIn] Christel Weiss [verfasserIn] Angela Köninger [verfasserIn] Ursula Felderhoff-Müser [verfasserIn] Hanna Müller [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	amniotic fluid anhydramnios preterm infant preterm premature rupture of membranes serum creatinine

Übergeordnetes Werk:	In: Pediatrics and Neonatology - Elsevier, 2017, 61(2020), 4, Seite 414-419
Übergeordnetes Werk:	volume:61 ; year:2020 ; number:4 ; pages:414-419

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.pedneo.2020.03.010

Katalog-ID:	DOAJ069229619

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520			\|a Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios.
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allfields	10.1016/j.pedneo.2020.03.010 doi (DE-627)DOAJ069229619 (DE-599)DOAJea30c8d3dc4440b88ed127212f21933f DE-627 ger DE-627 rakwb eng RJ1-570 Nora Bruns verfasserin aut Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios. amniotic fluid anhydramnios preterm infant preterm premature rupture of membranes serum creatinine Pediatrics Ann-Christin Stähling verfasserin aut Sandra Greve verfasserin aut Christel Weiss verfasserin aut Angela Köninger verfasserin aut Ursula Felderhoff-Müser verfasserin aut Hanna Müller verfasserin aut In Pediatrics and Neonatology Elsevier, 2017 61(2020), 4, Seite 414-419 (DE-627)573750971 (DE-600)2441821-3 18759572 nnns volume:61 year:2020 number:4 pages:414-419 https://doi.org/10.1016/j.pedneo.2020.03.010 kostenfrei https://doaj.org/article/ea30c8d3dc4440b88ed127212f21933f kostenfrei http://www.sciencedirect.com/science/article/pii/S1875957220300498 kostenfrei https://doaj.org/toc/1875-9572 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2020 4 414-419
spelling	10.1016/j.pedneo.2020.03.010 doi (DE-627)DOAJ069229619 (DE-599)DOAJea30c8d3dc4440b88ed127212f21933f DE-627 ger DE-627 rakwb eng RJ1-570 Nora Bruns verfasserin aut Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios. amniotic fluid anhydramnios preterm infant preterm premature rupture of membranes serum creatinine Pediatrics Ann-Christin Stähling verfasserin aut Sandra Greve verfasserin aut Christel Weiss verfasserin aut Angela Köninger verfasserin aut Ursula Felderhoff-Müser verfasserin aut Hanna Müller verfasserin aut In Pediatrics and Neonatology Elsevier, 2017 61(2020), 4, Seite 414-419 (DE-627)573750971 (DE-600)2441821-3 18759572 nnns volume:61 year:2020 number:4 pages:414-419 https://doi.org/10.1016/j.pedneo.2020.03.010 kostenfrei https://doaj.org/article/ea30c8d3dc4440b88ed127212f21933f kostenfrei http://www.sciencedirect.com/science/article/pii/S1875957220300498 kostenfrei https://doaj.org/toc/1875-9572 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2020 4 414-419
allfields_unstemmed	10.1016/j.pedneo.2020.03.010 doi (DE-627)DOAJ069229619 (DE-599)DOAJea30c8d3dc4440b88ed127212f21933f DE-627 ger DE-627 rakwb eng RJ1-570 Nora Bruns verfasserin aut Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios. amniotic fluid anhydramnios preterm infant preterm premature rupture of membranes serum creatinine Pediatrics Ann-Christin Stähling verfasserin aut Sandra Greve verfasserin aut Christel Weiss verfasserin aut Angela Köninger verfasserin aut Ursula Felderhoff-Müser verfasserin aut Hanna Müller verfasserin aut In Pediatrics and Neonatology Elsevier, 2017 61(2020), 4, Seite 414-419 (DE-627)573750971 (DE-600)2441821-3 18759572 nnns volume:61 year:2020 number:4 pages:414-419 https://doi.org/10.1016/j.pedneo.2020.03.010 kostenfrei https://doaj.org/article/ea30c8d3dc4440b88ed127212f21933f kostenfrei http://www.sciencedirect.com/science/article/pii/S1875957220300498 kostenfrei https://doaj.org/toc/1875-9572 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2020 4 414-419
allfieldsGer	10.1016/j.pedneo.2020.03.010 doi (DE-627)DOAJ069229619 (DE-599)DOAJea30c8d3dc4440b88ed127212f21933f DE-627 ger DE-627 rakwb eng RJ1-570 Nora Bruns verfasserin aut Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios. amniotic fluid anhydramnios preterm infant preterm premature rupture of membranes serum creatinine Pediatrics Ann-Christin Stähling verfasserin aut Sandra Greve verfasserin aut Christel Weiss verfasserin aut Angela Köninger verfasserin aut Ursula Felderhoff-Müser verfasserin aut Hanna Müller verfasserin aut In Pediatrics and Neonatology Elsevier, 2017 61(2020), 4, Seite 414-419 (DE-627)573750971 (DE-600)2441821-3 18759572 nnns volume:61 year:2020 number:4 pages:414-419 https://doi.org/10.1016/j.pedneo.2020.03.010 kostenfrei https://doaj.org/article/ea30c8d3dc4440b88ed127212f21933f kostenfrei http://www.sciencedirect.com/science/article/pii/S1875957220300498 kostenfrei https://doaj.org/toc/1875-9572 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2020 4 414-419
allfieldsSound	10.1016/j.pedneo.2020.03.010 doi (DE-627)DOAJ069229619 (DE-599)DOAJea30c8d3dc4440b88ed127212f21933f DE-627 ger DE-627 rakwb eng RJ1-570 Nora Bruns verfasserin aut Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios. amniotic fluid anhydramnios preterm infant preterm premature rupture of membranes serum creatinine Pediatrics Ann-Christin Stähling verfasserin aut Sandra Greve verfasserin aut Christel Weiss verfasserin aut Angela Köninger verfasserin aut Ursula Felderhoff-Müser verfasserin aut Hanna Müller verfasserin aut In Pediatrics and Neonatology Elsevier, 2017 61(2020), 4, Seite 414-419 (DE-627)573750971 (DE-600)2441821-3 18759572 nnns volume:61 year:2020 number:4 pages:414-419 https://doi.org/10.1016/j.pedneo.2020.03.010 kostenfrei https://doaj.org/article/ea30c8d3dc4440b88ed127212f21933f kostenfrei http://www.sciencedirect.com/science/article/pii/S1875957220300498 kostenfrei https://doaj.org/toc/1875-9572 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2020 4 414-419
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On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). 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author	Nora Bruns
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topic_title	RJ1-570 Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios amniotic fluid anhydramnios preterm infant preterm premature rupture of membranes serum creatinine
topic	misc RJ1-570 misc amniotic fluid misc anhydramnios misc preterm infant misc preterm premature rupture of membranes misc serum creatinine misc Pediatrics
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title	Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios
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title_full	Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios
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author_browse	Nora Bruns Ann-Christin Stähling Sandra Greve Christel Weiss Angela Köninger Ursula Felderhoff-Müser Hanna Müller
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title_sort	postnatal serum creatinine is elevated in preterm infants with pprom-induced anhydramnios
callnumber	RJ1-570
title_auth	Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios
abstract	Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios.
abstractGer	Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios.
abstract_unstemmed	Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM). Methods: 74 preterm infants with PPROM < 48 h duration were retrospectively studied. Postnatal creatinine concentration was determined at day 2–5, 10–17 and 26–33 of life and compared between infants with normal intrauterine amniotic volumes, oligohydramnios and anhydramnios. Results: Mean gestational age of included patients was 29.7 weeks (range: 24.0–36.1 weeks) and mean birth weight was 1452 g (range: 560–2940 g). Serum creatinine concentration was similar at day 2–5 and day 10–17 of life between the three groups. We observed a significant decrease in creatinine concentration from day 2–5 to day 26–33 in infants with normal amniotic fluid volume and oligohydramnios (p = 0.0001 and p = 0.0071, respectively), but not in anhydramnios. On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). Conclusion: Postnatal serum creatinine of preterm infants at day 26–33 of life is elevated in infants with PPROM-induced anhydramnios, but not in oligohydramnios.
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title_short	Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios
url	https://doi.org/10.1016/j.pedneo.2020.03.010 https://doaj.org/article/ea30c8d3dc4440b88ed127212f21933f http://www.sciencedirect.com/science/article/pii/S1875957220300498 https://doaj.org/toc/1875-9572
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author2	Ann-Christin Stähling Sandra Greve Christel Weiss Angela Köninger Ursula Felderhoff-Müser Hanna Müller
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up_date	2024-07-03T22:11:38.523Z
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On day 26–33 of life, infants with anhydramnios showed significantly higher creatinine levels compared to infants with normal amniotic fluid volume and oligohydramnios (p = 0.0211). 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code="a">Sandra Greve</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Christel Weiss</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Angela Köninger</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ursula Felderhoff-Müser</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hanna Müller</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Pediatrics and Neonatology</subfield><subfield code="d">Elsevier, 2017</subfield><subfield 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Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios

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