Resting Energy Expenditure Is Elevated in Asthma

<b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to...
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Autor*in:	Jacob T. Mey [verfasserIn] Brittany Matuska [verfasserIn] Laura Peterson [verfasserIn] Patrick Wyszynski [verfasserIn] Michelle Koo [verfasserIn] Jacqueline Sharp [verfasserIn] Emily Pennington [verfasserIn] Stephanie McCarroll [verfasserIn] Sarah Micklewright [verfasserIn] Peng Zhang [verfasserIn] Mark Aronica [verfasserIn] Kristin K. Hoddy [verfasserIn] Catherine M. Champagne [verfasserIn] Steven B. Heymsfield [verfasserIn] Suzy A. A. Comhair [verfasserIn] John P. Kirwan [verfasserIn] Serpil C. Erzurum [verfasserIn] Anny Mulya [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	resting energy expenditure body composition nutrition respiratory function airway inflammation

Übergeordnetes Werk:	In: Nutrients - MDPI AG, 2009, 13(2021), 4, p 1065
Übergeordnetes Werk:	volume:13 ; year:2021 ; number:4, p 1065

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/nu13041065

Katalog-ID:	DOAJ069280967

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520			\|a <b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma.
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650		4	\|a airway inflammation
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allfields	10.3390/nu13041065 doi (DE-627)DOAJ069280967 (DE-599)DOAJ8555df1bb2cf4d1abdb5e40811a71645 DE-627 ger DE-627 rakwb eng TX341-641 Jacob T. Mey verfasserin aut Resting Energy Expenditure Is Elevated in Asthma 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma. resting energy expenditure body composition nutrition respiratory function airway inflammation Nutrition. Foods and food supply Brittany Matuska verfasserin aut Laura Peterson verfasserin aut Patrick Wyszynski verfasserin aut Michelle Koo verfasserin aut Jacqueline Sharp verfasserin aut Emily Pennington verfasserin aut Stephanie McCarroll verfasserin aut Sarah Micklewright verfasserin aut Peng Zhang verfasserin aut Mark Aronica verfasserin aut Kristin K. Hoddy verfasserin aut Catherine M. Champagne verfasserin aut Steven B. Heymsfield verfasserin aut Suzy A. A. Comhair verfasserin aut John P. Kirwan verfasserin aut Serpil C. Erzurum verfasserin aut Anny Mulya verfasserin aut In Nutrients MDPI AG, 2009 13(2021), 4, p 1065 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:13 year:2021 number:4, p 1065 https://doi.org/10.3390/nu13041065 kostenfrei https://doaj.org/article/8555df1bb2cf4d1abdb5e40811a71645 kostenfrei https://www.mdpi.com/2072-6643/13/4/1065 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2021 4, p 1065
spelling	10.3390/nu13041065 doi (DE-627)DOAJ069280967 (DE-599)DOAJ8555df1bb2cf4d1abdb5e40811a71645 DE-627 ger DE-627 rakwb eng TX341-641 Jacob T. Mey verfasserin aut Resting Energy Expenditure Is Elevated in Asthma 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma. resting energy expenditure body composition nutrition respiratory function airway inflammation Nutrition. Foods and food supply Brittany Matuska verfasserin aut Laura Peterson verfasserin aut Patrick Wyszynski verfasserin aut Michelle Koo verfasserin aut Jacqueline Sharp verfasserin aut Emily Pennington verfasserin aut Stephanie McCarroll verfasserin aut Sarah Micklewright verfasserin aut Peng Zhang verfasserin aut Mark Aronica verfasserin aut Kristin K. Hoddy verfasserin aut Catherine M. Champagne verfasserin aut Steven B. Heymsfield verfasserin aut Suzy A. A. Comhair verfasserin aut John P. Kirwan verfasserin aut Serpil C. Erzurum verfasserin aut Anny Mulya verfasserin aut In Nutrients MDPI AG, 2009 13(2021), 4, p 1065 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:13 year:2021 number:4, p 1065 https://doi.org/10.3390/nu13041065 kostenfrei https://doaj.org/article/8555df1bb2cf4d1abdb5e40811a71645 kostenfrei https://www.mdpi.com/2072-6643/13/4/1065 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2021 4, p 1065
allfields_unstemmed	10.3390/nu13041065 doi (DE-627)DOAJ069280967 (DE-599)DOAJ8555df1bb2cf4d1abdb5e40811a71645 DE-627 ger DE-627 rakwb eng TX341-641 Jacob T. Mey verfasserin aut Resting Energy Expenditure Is Elevated in Asthma 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma. resting energy expenditure body composition nutrition respiratory function airway inflammation Nutrition. Foods and food supply Brittany Matuska verfasserin aut Laura Peterson verfasserin aut Patrick Wyszynski verfasserin aut Michelle Koo verfasserin aut Jacqueline Sharp verfasserin aut Emily Pennington verfasserin aut Stephanie McCarroll verfasserin aut Sarah Micklewright verfasserin aut Peng Zhang verfasserin aut Mark Aronica verfasserin aut Kristin K. Hoddy verfasserin aut Catherine M. Champagne verfasserin aut Steven B. Heymsfield verfasserin aut Suzy A. A. Comhair verfasserin aut John P. Kirwan verfasserin aut Serpil C. Erzurum verfasserin aut Anny Mulya verfasserin aut In Nutrients MDPI AG, 2009 13(2021), 4, p 1065 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:13 year:2021 number:4, p 1065 https://doi.org/10.3390/nu13041065 kostenfrei https://doaj.org/article/8555df1bb2cf4d1abdb5e40811a71645 kostenfrei https://www.mdpi.com/2072-6643/13/4/1065 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2021 4, p 1065
allfieldsGer	10.3390/nu13041065 doi (DE-627)DOAJ069280967 (DE-599)DOAJ8555df1bb2cf4d1abdb5e40811a71645 DE-627 ger DE-627 rakwb eng TX341-641 Jacob T. Mey verfasserin aut Resting Energy Expenditure Is Elevated in Asthma 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma. resting energy expenditure body composition nutrition respiratory function airway inflammation Nutrition. Foods and food supply Brittany Matuska verfasserin aut Laura Peterson verfasserin aut Patrick Wyszynski verfasserin aut Michelle Koo verfasserin aut Jacqueline Sharp verfasserin aut Emily Pennington verfasserin aut Stephanie McCarroll verfasserin aut Sarah Micklewright verfasserin aut Peng Zhang verfasserin aut Mark Aronica verfasserin aut Kristin K. Hoddy verfasserin aut Catherine M. Champagne verfasserin aut Steven B. Heymsfield verfasserin aut Suzy A. A. Comhair verfasserin aut John P. Kirwan verfasserin aut Serpil C. Erzurum verfasserin aut Anny Mulya verfasserin aut In Nutrients MDPI AG, 2009 13(2021), 4, p 1065 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:13 year:2021 number:4, p 1065 https://doi.org/10.3390/nu13041065 kostenfrei https://doaj.org/article/8555df1bb2cf4d1abdb5e40811a71645 kostenfrei https://www.mdpi.com/2072-6643/13/4/1065 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2021 4, p 1065
allfieldsSound	10.3390/nu13041065 doi (DE-627)DOAJ069280967 (DE-599)DOAJ8555df1bb2cf4d1abdb5e40811a71645 DE-627 ger DE-627 rakwb eng TX341-641 Jacob T. Mey verfasserin aut Resting Energy Expenditure Is Elevated in Asthma 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma. resting energy expenditure body composition nutrition respiratory function airway inflammation Nutrition. Foods and food supply Brittany Matuska verfasserin aut Laura Peterson verfasserin aut Patrick Wyszynski verfasserin aut Michelle Koo verfasserin aut Jacqueline Sharp verfasserin aut Emily Pennington verfasserin aut Stephanie McCarroll verfasserin aut Sarah Micklewright verfasserin aut Peng Zhang verfasserin aut Mark Aronica verfasserin aut Kristin K. Hoddy verfasserin aut Catherine M. Champagne verfasserin aut Steven B. Heymsfield verfasserin aut Suzy A. A. Comhair verfasserin aut John P. Kirwan verfasserin aut Serpil C. Erzurum verfasserin aut Anny Mulya verfasserin aut In Nutrients MDPI AG, 2009 13(2021), 4, p 1065 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:13 year:2021 number:4, p 1065 https://doi.org/10.3390/nu13041065 kostenfrei https://doaj.org/article/8555df1bb2cf4d1abdb5e40811a71645 kostenfrei https://www.mdpi.com/2072-6643/13/4/1065 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2021 4, p 1065
language	English
source	In Nutrients 13(2021), 4, p 1065 volume:13 year:2021 number:4, p 1065
sourceStr	In Nutrients 13(2021), 4, p 1065 volume:13 year:2021 number:4, p 1065
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	resting energy expenditure body composition nutrition respiratory function airway inflammation Nutrition. Foods and food supply
isfreeaccess_bool	true
container_title	Nutrients
authorswithroles_txt_mv	Jacob T. Mey @@aut@@ Brittany Matuska @@aut@@ Laura Peterson @@aut@@ Patrick Wyszynski @@aut@@ Michelle Koo @@aut@@ Jacqueline Sharp @@aut@@ Emily Pennington @@aut@@ Stephanie McCarroll @@aut@@ Sarah Micklewright @@aut@@ Peng Zhang @@aut@@ Mark Aronica @@aut@@ Kristin K. Hoddy @@aut@@ Catherine M. Champagne @@aut@@ Steven B. Heymsfield @@aut@@ Suzy A. A. Comhair @@aut@@ John P. Kirwan @@aut@@ Serpil C. Erzurum @@aut@@ Anny Mulya @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	610604155
id	DOAJ069280967
language_de	englisch
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callnumber-first	T - Technology
author	Jacob T. Mey
spellingShingle	Jacob T. Mey misc TX341-641 misc resting energy expenditure misc body composition misc nutrition misc respiratory function misc airway inflammation misc Nutrition. Foods and food supply Resting Energy Expenditure Is Elevated in Asthma
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topic_title	TX341-641 Resting Energy Expenditure Is Elevated in Asthma resting energy expenditure body composition nutrition respiratory function airway inflammation
topic	misc TX341-641 misc resting energy expenditure misc body composition misc nutrition misc respiratory function misc airway inflammation misc Nutrition. Foods and food supply
topic_unstemmed	misc TX341-641 misc resting energy expenditure misc body composition misc nutrition misc respiratory function misc airway inflammation misc Nutrition. Foods and food supply
topic_browse	misc TX341-641 misc resting energy expenditure misc body composition misc nutrition misc respiratory function misc airway inflammation misc Nutrition. Foods and food supply
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title	Resting Energy Expenditure Is Elevated in Asthma
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title_full	Resting Energy Expenditure Is Elevated in Asthma
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author_browse	Jacob T. Mey Brittany Matuska Laura Peterson Patrick Wyszynski Michelle Koo Jacqueline Sharp Emily Pennington Stephanie McCarroll Sarah Micklewright Peng Zhang Mark Aronica Kristin K. Hoddy Catherine M. Champagne Steven B. Heymsfield Suzy A. A. Comhair John P. Kirwan Serpil C. Erzurum Anny Mulya
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author-letter	Jacob T. Mey
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title_sort	resting energy expenditure is elevated in asthma
callnumber	TX341-641
title_auth	Resting Energy Expenditure Is Elevated in Asthma
abstract	<b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma.
abstractGer	<b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma.
abstract_unstemmed	<b<Background:</b< Asthma physiology affects respiratory function and inflammation, factors that may contribute to elevated resting energy expenditure (REE) and altered body composition. <b<Objective:</b< We hypothesized that asthma would present with elevated REE compared to weight-matched healthy controls. <b<Methods:</b< Adults with asthma (<i<n</i< = 41) and healthy controls (<i<n</i< = 20) underwent indirect calorimetry to measure REE, dual-energy X-ray absorptiometry (DEXA) to measure body composition, and 3-day diet records. Clinical assessments included spirometry, fractional exhaled nitric oxide (FENO), and a complete blood count. <b<Results:</b< Asthmatics had greater REE than controls amounting to an increase of ~100 kcals/day, even though body mass index (BMI) and body composition were similar between groups. Inclusion of asthma status and FENO in validated REE prediction equations led to improved estimates. Further, asthmatics had higher white blood cell (control vs. asthma (mean ± SD): 4.7 ± 1.1 vs. 5.9 ± 1.6, <i<p</i< < 0.01) and neutrophil (2.8 ± 0.9 vs. 3.6 ± 1.4, <i<p</i< = 0.02) counts that correlated with REE (both <i<p</i< < 0.01). Interestingly, despite higher REE, asthmatics reported consuming fewer calories (25.1 ± 7.5 vs. 20.3 ± 6.0 kcals/kg/day, <i<p</i< < 0.01) and carbohydrates than controls. <b<Conclusion:</b< REE is elevated in adults with mild asthma, suggesting there is an association between REE and the pathophysiology of asthma.
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