Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome?
Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CH...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Banović Marko [verfasserIn] Vasiljević-Pokrajčić Zorana [verfasserIn] Vujisić-Tešić Bosiljka [verfasserIn] Stanković Sanja [verfasserIn] Nedeljković Ivana [verfasserIn] Petrović Olga [verfasserIn] Otašević Petar [verfasserIn] Boričić-Kostić Marija [verfasserIn] Petrović Milan [verfasserIn] Trifunović Danijela [verfasserIn] Ostojić Miodrag [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch ; srp |
| Erschienen: |
2010 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Srpski Arhiv za Celokupno Lekarstvo - Serbian Medical Society, 2010, 138(2010), 3-4, Seite 162-169 |
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| Übergeordnetes Werk: |
volume:138 ; year:2010 ; number:3-4 ; pages:162-169 |
| Links: |
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| DOI / URN: |
10.2298/SARH1004162B |
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| Katalog-ID: |
DOAJ069808805 |
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| 520 | |a Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. | ||
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10.2298/SARH1004162B doi (DE-627)DOAJ069808805 (DE-599)DOAJ7e43035c85ad4b97aa307cc3004e0676 DE-627 ger DE-627 rakwb eng srp Banović Marko verfasserin aut Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome? 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. acute heart failure echocardiography natriuretic Peptides Medicine R Vasiljević-Pokrajčić Zorana verfasserin aut Vujisić-Tešić Bosiljka verfasserin aut Stanković Sanja verfasserin aut Nedeljković Ivana verfasserin aut Petrović Olga verfasserin aut Otašević Petar verfasserin aut Boričić-Kostić Marija verfasserin aut Petrović Milan verfasserin aut Trifunović Danijela verfasserin aut Ostojić Miodrag verfasserin aut In Srpski Arhiv za Celokupno Lekarstvo Serbian Medical Society, 2010 138(2010), 3-4, Seite 162-169 (DE-627)637421205 (DE-600)2577665-4 24060895 nnns volume:138 year:2010 number:3-4 pages:162-169 https://doi.org/10.2298/SARH1004162B kostenfrei https://doaj.org/article/7e43035c85ad4b97aa307cc3004e0676 kostenfrei http://www.doiserbia.nb.rs/img/doi/0370-8179/2010/0370-81791004162B.pdf kostenfrei https://doaj.org/toc/0370-8179 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 138 2010 3-4 162-169 |
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10.2298/SARH1004162B doi (DE-627)DOAJ069808805 (DE-599)DOAJ7e43035c85ad4b97aa307cc3004e0676 DE-627 ger DE-627 rakwb eng srp Banović Marko verfasserin aut Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome? 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. acute heart failure echocardiography natriuretic Peptides Medicine R Vasiljević-Pokrajčić Zorana verfasserin aut Vujisić-Tešić Bosiljka verfasserin aut Stanković Sanja verfasserin aut Nedeljković Ivana verfasserin aut Petrović Olga verfasserin aut Otašević Petar verfasserin aut Boričić-Kostić Marija verfasserin aut Petrović Milan verfasserin aut Trifunović Danijela verfasserin aut Ostojić Miodrag verfasserin aut In Srpski Arhiv za Celokupno Lekarstvo Serbian Medical Society, 2010 138(2010), 3-4, Seite 162-169 (DE-627)637421205 (DE-600)2577665-4 24060895 nnns volume:138 year:2010 number:3-4 pages:162-169 https://doi.org/10.2298/SARH1004162B kostenfrei https://doaj.org/article/7e43035c85ad4b97aa307cc3004e0676 kostenfrei http://www.doiserbia.nb.rs/img/doi/0370-8179/2010/0370-81791004162B.pdf kostenfrei https://doaj.org/toc/0370-8179 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 138 2010 3-4 162-169 |
| allfields_unstemmed |
10.2298/SARH1004162B doi (DE-627)DOAJ069808805 (DE-599)DOAJ7e43035c85ad4b97aa307cc3004e0676 DE-627 ger DE-627 rakwb eng srp Banović Marko verfasserin aut Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome? 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. acute heart failure echocardiography natriuretic Peptides Medicine R Vasiljević-Pokrajčić Zorana verfasserin aut Vujisić-Tešić Bosiljka verfasserin aut Stanković Sanja verfasserin aut Nedeljković Ivana verfasserin aut Petrović Olga verfasserin aut Otašević Petar verfasserin aut Boričić-Kostić Marija verfasserin aut Petrović Milan verfasserin aut Trifunović Danijela verfasserin aut Ostojić Miodrag verfasserin aut In Srpski Arhiv za Celokupno Lekarstvo Serbian Medical Society, 2010 138(2010), 3-4, Seite 162-169 (DE-627)637421205 (DE-600)2577665-4 24060895 nnns volume:138 year:2010 number:3-4 pages:162-169 https://doi.org/10.2298/SARH1004162B kostenfrei https://doaj.org/article/7e43035c85ad4b97aa307cc3004e0676 kostenfrei http://www.doiserbia.nb.rs/img/doi/0370-8179/2010/0370-81791004162B.pdf kostenfrei https://doaj.org/toc/0370-8179 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 138 2010 3-4 162-169 |
| allfieldsGer |
10.2298/SARH1004162B doi (DE-627)DOAJ069808805 (DE-599)DOAJ7e43035c85ad4b97aa307cc3004e0676 DE-627 ger DE-627 rakwb eng srp Banović Marko verfasserin aut Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome? 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. acute heart failure echocardiography natriuretic Peptides Medicine R Vasiljević-Pokrajčić Zorana verfasserin aut Vujisić-Tešić Bosiljka verfasserin aut Stanković Sanja verfasserin aut Nedeljković Ivana verfasserin aut Petrović Olga verfasserin aut Otašević Petar verfasserin aut Boričić-Kostić Marija verfasserin aut Petrović Milan verfasserin aut Trifunović Danijela verfasserin aut Ostojić Miodrag verfasserin aut In Srpski Arhiv za Celokupno Lekarstvo Serbian Medical Society, 2010 138(2010), 3-4, Seite 162-169 (DE-627)637421205 (DE-600)2577665-4 24060895 nnns volume:138 year:2010 number:3-4 pages:162-169 https://doi.org/10.2298/SARH1004162B kostenfrei https://doaj.org/article/7e43035c85ad4b97aa307cc3004e0676 kostenfrei http://www.doiserbia.nb.rs/img/doi/0370-8179/2010/0370-81791004162B.pdf kostenfrei https://doaj.org/toc/0370-8179 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 138 2010 3-4 162-169 |
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10.2298/SARH1004162B doi (DE-627)DOAJ069808805 (DE-599)DOAJ7e43035c85ad4b97aa307cc3004e0676 DE-627 ger DE-627 rakwb eng srp Banović Marko verfasserin aut Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome? 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. acute heart failure echocardiography natriuretic Peptides Medicine R Vasiljević-Pokrajčić Zorana verfasserin aut Vujisić-Tešić Bosiljka verfasserin aut Stanković Sanja verfasserin aut Nedeljković Ivana verfasserin aut Petrović Olga verfasserin aut Otašević Petar verfasserin aut Boričić-Kostić Marija verfasserin aut Petrović Milan verfasserin aut Trifunović Danijela verfasserin aut Ostojić Miodrag verfasserin aut In Srpski Arhiv za Celokupno Lekarstvo Serbian Medical Society, 2010 138(2010), 3-4, Seite 162-169 (DE-627)637421205 (DE-600)2577665-4 24060895 nnns volume:138 year:2010 number:3-4 pages:162-169 https://doi.org/10.2298/SARH1004162B kostenfrei https://doaj.org/article/7e43035c85ad4b97aa307cc3004e0676 kostenfrei http://www.doiserbia.nb.rs/img/doi/0370-8179/2010/0370-81791004162B.pdf kostenfrei https://doaj.org/toc/0370-8179 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 138 2010 3-4 162-169 |
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Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome? |
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Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. |
| abstractGer |
Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. |
| abstract_unstemmed |
Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p<0.05), urea (12.63 vs 7.82 mmol/l; p<0.05), BNP (1440.11 vs 712.24 pg/ml; p<001) and NTproBNP (9097.00 vs 2827.70 pg/ml; p<0.01) on admission, and lower values of M-mode left ventricular ejection fraction (LVEF) during hospitalization (49.44% vs 42.94%; p<0.05). The follow-up after one year revealed still significantly higher BNP (365.49 vs 164.02 pg/ ml; p<0.05) and lower average values of both LVEF in patients with acutely worsened CHF (46.62% vs 54.41% and 39.52% vs 47.88%; p<0.05). Conclusion. Considering differences in clinical severity on admission, echocardiography and natriuretic peptide values during hospitalization and after one year follow-up, de novo AHF and acutely worsened CHF are two different subgroups of the same syndrome. |
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Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome? |
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https://doi.org/10.2298/SARH1004162B https://doaj.org/article/7e43035c85ad4b97aa307cc3004e0676 http://www.doiserbia.nb.rs/img/doi/0370-8179/2010/0370-81791004162B.pdf https://doaj.org/toc/0370-8179 |
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Vasiljević-Pokrajčić Zorana Vujisić-Tešić Bosiljka Stanković Sanja Nedeljković Ivana Petrović Olga Otašević Petar Boričić-Kostić Marija Petrović Milan Trifunović Danijela Ostojić Miodrag |
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Vasiljević-Pokrajčić Zorana Vujisić-Tešić Bosiljka Stanković Sanja Nedeljković Ivana Petrović Olga Otašević Petar Boričić-Kostić Marija Petrović Milan Trifunović Danijela Ostojić Miodrag |
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