Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity

Fifty-seven compounds were purified from the stems of Tinospora sinensis, including three new compounds characterized as a lignan (1), a pyrrole alkaloid (11), and a benzenoid (17), respectively. Their structures were elucidated and established by various spectroscopic and spectrometric analytical m...
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Autor*in:	Sio-Hong Lam [verfasserIn] Po-Hsun Chen [verfasserIn] Hsin-Yi Hung [verfasserIn] Tsong-Long Hwang [verfasserIn] Chih-Chao Chiang [verfasserIn] Tran Dinh Thang [verfasserIn] Ping-Chung Kuo [verfasserIn] Tian-Shung Wu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Menispermaceae lignan pyrrole alkaloid superoxide anion generation elastase release

Übergeordnetes Werk:	In: Molecules - MDPI AG, 2003, 23(2018), 10, p 2541
Übergeordnetes Werk:	volume:23 ; year:2018 ; number:10, p 2541

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/molecules23102541

Katalog-ID:	DOAJ07066336X

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language	English
source	In Molecules 23(2018), 10, p 2541 volume:23 year:2018 number:10, p 2541
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topic_facet	Menispermaceae lignan pyrrole alkaloid superoxide anion generation elastase release Organic chemistry
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authorswithroles_txt_mv	Sio-Hong Lam @@aut@@ Po-Hsun Chen @@aut@@ Hsin-Yi Hung @@aut@@ Tsong-Long Hwang @@aut@@ Chih-Chao Chiang @@aut@@ Tran Dinh Thang @@aut@@ Ping-Chung Kuo @@aut@@ Tian-Shung Wu @@aut@@
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callnumber-first	Q - Science
author	Sio-Hong Lam
spellingShingle	Sio-Hong Lam misc QD241-441 misc Menispermaceae misc lignan misc pyrrole alkaloid misc superoxide anion generation misc elastase release misc Organic chemistry Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity
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topic_title	QD241-441 Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity Menispermaceae lignan pyrrole alkaloid superoxide anion generation elastase release
topic	misc QD241-441 misc Menispermaceae misc lignan misc pyrrole alkaloid misc superoxide anion generation misc elastase release misc Organic chemistry
topic_unstemmed	misc QD241-441 misc Menispermaceae misc lignan misc pyrrole alkaloid misc superoxide anion generation misc elastase release misc Organic chemistry
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title	Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity
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title_full	Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity
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author_browse	Sio-Hong Lam Po-Hsun Chen Hsin-Yi Hung Tsong-Long Hwang Chih-Chao Chiang Tran Dinh Thang Ping-Chung Kuo Tian-Shung Wu
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title_sort	chemical constituents from the stems of tinospora sinensis and their bioactivity
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title_auth	Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity
abstract	Fifty-seven compounds were purified from the stems of Tinospora sinensis, including three new compounds characterized as a lignan (1), a pyrrole alkaloid (11), and a benzenoid (17), respectively. Their structures were elucidated and established by various spectroscopic and spectrometric analytical methods. Among the isolates, fifteen compounds were examined for their anti-inflammatory potential in vitro. The results showed that several compounds displayed moderate inhibition of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.
abstractGer	Fifty-seven compounds were purified from the stems of Tinospora sinensis, including three new compounds characterized as a lignan (1), a pyrrole alkaloid (11), and a benzenoid (17), respectively. Their structures were elucidated and established by various spectroscopic and spectrometric analytical methods. Among the isolates, fifteen compounds were examined for their anti-inflammatory potential in vitro. The results showed that several compounds displayed moderate inhibition of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.
abstract_unstemmed	Fifty-seven compounds were purified from the stems of Tinospora sinensis, including three new compounds characterized as a lignan (1), a pyrrole alkaloid (11), and a benzenoid (17), respectively. Their structures were elucidated and established by various spectroscopic and spectrometric analytical methods. Among the isolates, fifteen compounds were examined for their anti-inflammatory potential in vitro. The results showed that several compounds displayed moderate inhibition of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.
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container_issue	10, p 2541
title_short	Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity
url	https://doi.org/10.3390/molecules23102541 https://doaj.org/article/d5ce2899f1a6437f833a8aeb197a9222 http://www.mdpi.com/1420-3049/23/10/2541 https://doaj.org/toc/1420-3049
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Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity

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