The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits

To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was im...
Ausführliche Beschreibung

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Autor*in:	Ahmed Q. Al-Awadi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	P. aeruginosa, Arthritis, Rabbits.

Übergeordnetes Werk:	In: The Iraqi Journal of Veterinary Medicine - University of Baghdad, College of Veterinary Medicine, 2021, 38(2014), 1
Übergeordnetes Werk:	volume:38 ; year:2014 ; number:1

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.30539/iraqijvm.v38i1.246

Katalog-ID:	DOAJ071568573

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520			\|a To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model.
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allfields	10.30539/iraqijvm.v38i1.246 doi (DE-627)DOAJ071568573 (DE-599)DOAJ82a9751ed71e4211b0826e56c1af2e43 DE-627 ger DE-627 rakwb eng SF600-1100 Ahmed Q. Al-Awadi verfasserin aut The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model. P. aeruginosa, Arthritis, Rabbits. Veterinary medicine In The Iraqi Journal of Veterinary Medicine University of Baghdad, College of Veterinary Medicine, 2021 38(2014), 1 (DE-627)756299616 (DE-600)2726324-1 24107409 nnns volume:38 year:2014 number:1 https://doi.org/10.30539/iraqijvm.v38i1.246 kostenfrei https://doaj.org/article/82a9751ed71e4211b0826e56c1af2e43 kostenfrei https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/246 kostenfrei https://doaj.org/toc/1609-5693 Journal toc kostenfrei https://doaj.org/toc/2410-7409 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2014 1
spelling	10.30539/iraqijvm.v38i1.246 doi (DE-627)DOAJ071568573 (DE-599)DOAJ82a9751ed71e4211b0826e56c1af2e43 DE-627 ger DE-627 rakwb eng SF600-1100 Ahmed Q. Al-Awadi verfasserin aut The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model. P. aeruginosa, Arthritis, Rabbits. Veterinary medicine In The Iraqi Journal of Veterinary Medicine University of Baghdad, College of Veterinary Medicine, 2021 38(2014), 1 (DE-627)756299616 (DE-600)2726324-1 24107409 nnns volume:38 year:2014 number:1 https://doi.org/10.30539/iraqijvm.v38i1.246 kostenfrei https://doaj.org/article/82a9751ed71e4211b0826e56c1af2e43 kostenfrei https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/246 kostenfrei https://doaj.org/toc/1609-5693 Journal toc kostenfrei https://doaj.org/toc/2410-7409 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2014 1
allfields_unstemmed	10.30539/iraqijvm.v38i1.246 doi (DE-627)DOAJ071568573 (DE-599)DOAJ82a9751ed71e4211b0826e56c1af2e43 DE-627 ger DE-627 rakwb eng SF600-1100 Ahmed Q. Al-Awadi verfasserin aut The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model. P. aeruginosa, Arthritis, Rabbits. Veterinary medicine In The Iraqi Journal of Veterinary Medicine University of Baghdad, College of Veterinary Medicine, 2021 38(2014), 1 (DE-627)756299616 (DE-600)2726324-1 24107409 nnns volume:38 year:2014 number:1 https://doi.org/10.30539/iraqijvm.v38i1.246 kostenfrei https://doaj.org/article/82a9751ed71e4211b0826e56c1af2e43 kostenfrei https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/246 kostenfrei https://doaj.org/toc/1609-5693 Journal toc kostenfrei https://doaj.org/toc/2410-7409 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2014 1
allfieldsGer	10.30539/iraqijvm.v38i1.246 doi (DE-627)DOAJ071568573 (DE-599)DOAJ82a9751ed71e4211b0826e56c1af2e43 DE-627 ger DE-627 rakwb eng SF600-1100 Ahmed Q. Al-Awadi verfasserin aut The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model. P. aeruginosa, Arthritis, Rabbits. Veterinary medicine In The Iraqi Journal of Veterinary Medicine University of Baghdad, College of Veterinary Medicine, 2021 38(2014), 1 (DE-627)756299616 (DE-600)2726324-1 24107409 nnns volume:38 year:2014 number:1 https://doi.org/10.30539/iraqijvm.v38i1.246 kostenfrei https://doaj.org/article/82a9751ed71e4211b0826e56c1af2e43 kostenfrei https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/246 kostenfrei https://doaj.org/toc/1609-5693 Journal toc kostenfrei https://doaj.org/toc/2410-7409 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2014 1
allfieldsSound	10.30539/iraqijvm.v38i1.246 doi (DE-627)DOAJ071568573 (DE-599)DOAJ82a9751ed71e4211b0826e56c1af2e43 DE-627 ger DE-627 rakwb eng SF600-1100 Ahmed Q. Al-Awadi verfasserin aut The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model. P. aeruginosa, Arthritis, Rabbits. Veterinary medicine In The Iraqi Journal of Veterinary Medicine University of Baghdad, College of Veterinary Medicine, 2021 38(2014), 1 (DE-627)756299616 (DE-600)2726324-1 24107409 nnns volume:38 year:2014 number:1 https://doi.org/10.30539/iraqijvm.v38i1.246 kostenfrei https://doaj.org/article/82a9751ed71e4211b0826e56c1af2e43 kostenfrei https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/246 kostenfrei https://doaj.org/toc/1609-5693 Journal toc kostenfrei https://doaj.org/toc/2410-7409 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2014 1
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Al-Awadi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. 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callnumber-first	S - Agriculture
author	Ahmed Q. Al-Awadi
spellingShingle	Ahmed Q. Al-Awadi misc SF600-1100 misc P. aeruginosa, Arthritis, Rabbits. misc Veterinary medicine The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits
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topic_title	SF600-1100 The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits P. aeruginosa, Arthritis, Rabbits
topic	misc SF600-1100 misc P. aeruginosa, Arthritis, Rabbits. misc Veterinary medicine
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title	The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits
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title_full	The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits
author_sort	Ahmed Q. Al-Awadi
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title_sort	influence of whole sonicated pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits
callnumber	SF600-1100
title_auth	The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits
abstract	To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model.
abstractGer	To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model.
abstract_unstemmed	To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p. aeruginosa suspension (2×108 cfu/ml), the 2nd group was immunized with WSP Ags, and inoculated intraarticular as in the 1st group. The 3rd group was served as negative control group. At 30 day post inoculation the immunized (2nd) group showed increase in the cellular (DTH and IFN-γ) and humeral (IgG) immunity and moderate bacterial isolation from joints, blood and internal organs comparing with other groups. The 1st group showed sever symptoms and inflammatory reaction as well as very obvious gross and microscopical lesions in their joints including supportive reaction, pyogranulomatous lesions, necrosis, pannus reaction and destruction of the articular cartilage and the lesion extended to the subchondral bone leading to osteomyelitis, the 2nd group (immunized group) expressed mild to moderate inflammatory reaction and the microscopic examination indicate that the lesion was confined in the articular capsule. In conclusion the whole Pseudononas aeruginosa sonicated Ags (WSPAgs) protect the joint from the experimental infection by P. aeruginosa in a rabbit model.
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title_short	The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits
url	https://doi.org/10.30539/iraqijvm.v38i1.246 https://doaj.org/article/82a9751ed71e4211b0826e56c1af2e43 https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/246 https://doaj.org/toc/1609-5693 https://doaj.org/toc/2410-7409
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The influence of whole sonicated Pseudomonas aeruginosa antigens on experimental p. aeruginosa arthritis in rabbits

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